糖心vlog

Object moved to here.

Values and Preferences of Patients and Caregivers Regarding Treatment of Atopic Dermatitis (Eczema): A Systematic Review | Atopic Dermatitis | JAMA Dermatology | 糖心vlog

糖心vlog

[Skip to Navigation]
Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue
糖心vlog Home
JAMA Dermatology
Sign In
full text icon
Full Text
 contents icon
Contents
 figure icon
Figures /
Tables
 multimedia icon
Multimedia
 attach icon
Supplemental
Content
 references icon
References
 related icon
Related
 comments icon
Comments
1.
Boguniewicz 听M锘�, Fonacier 听L锘�, Guttman-Yassky 听E锘�, Ong 听PY锘�, Silverberg 听J锘�, Farrar 听JR锘�. 听Atopic dermatitis yardstick: practical recommendations for an evolving therapeutic landscape.听锘� 听Ann Allergy Asthma Immunol. 2018;120(1):10-22.e2. doi:
2.
Bakaa 听L锘�, Pernica 听JM锘�, Couban 听RJ锘�, 听et al. 听Bleach baths for atopic dermatitis: a systematic review and meta-analysis including unpublished data, Bayesian interpretation, and GRADE.听锘� 听Ann Allergy Asthma Immunol. 2022;128(6):660-668.e9. doi:
3.
Oykhman 听P锘�, Dookie 听J锘�, Al-Rammahy 听H锘�, 听et al. 听Dietary elimination for the treatment of atopic dermatitis: a systematic review and meta-analysis.听锘� 听J Allergy Clin Immunol Pract. 2022;10(10):2657-2666.e8. doi:
4.
Chu 听DK锘�, Golden 听DBK锘�, Guyatt 听GH锘�. 听Translating evidence to optimize patient care using GRADE.听锘� 听J Allergy Clin Immunol Pract. 2021;9(12):4221-4230. doi:
5.
Schneider 听L锘�, Tilles 听S锘�, Lio 听P锘�, 听et al. 听Atopic dermatitis: a practice parameter update 2012.听锘� 听J Allergy Clin Immunol. 2013;131(2):295-9.e1, 27. doi:
6.
Agarwal 听A锘�, Chen 听L锘�, Capozza 听K锘�, 听et al. 听Trustworthy patient-centered guidelines: insights from atopic dermatitis and a proposal for the future.听锘� 听J Allergy Clin Immunol Pract. 2022;10(11):2875-2877. doi:
7.
Thomas 听J锘�, Harden 听A锘�. 听Methods for the thematic synthesis of qualitative research in systematic reviews.听锘� 听BMC Med Res Methodol. 2008;8:45. doi:
8.
Heen 听AF锘�, Lytvyn 听L锘�, Shapiro 听M锘�, 听et al. 听Patient values and preferences on valve replacement for aortic stenosis: a systematic review.听锘� 听贬别补谤迟. 2021;107(16):1289-1295. doi:
9.
Zeng 听L锘�, Lytvyn 听L锘�, Wang 听X锘�, 听et al. 听Values and preferences towards medical cannabis among people living with chronic pain: a mixed-methods systematic review.听锘� 听叠惭闯 Open. 2021;11(9):e050831. doi:
10.
Critical Appraisal Skills Programme. CASP qualitative studies checklist. Accessed December 13, 2022.
11.
Lewin 听S锘�, Bohren 听M锘�, Rashidian 听A锘�, 听et al. 听Applying GRADE-CERQual to qualitative evidence synthesis findings-paper 2: how to make an overall CERQual assessment of confidence and create a Summary of Qualitative Findings table.听锘� 听Implement Sci. 2018;13(suppl 1):10. doi:
12.
de Wijs 听LEM锘�, van Egmond 听S锘�, Devillers 听ACA锘�, Nijsten 听T锘�, Hijnen 听D锘�, Lugtenberg 听M锘�. 听Needs and preferences of patients regarding atopic dermatitis care in the era of new therapeutic options: a qualitative study.听锘� 听Arch Dermatol Res. 2022;1-9. doi:
13.
Clement 听C锘�, Ridd 听MJ锘�, Roberts 听K锘�, 听et al. 听Parents and GPs鈥� understandings and beliefs about food allergy testing in children with eczema: qualitative interview study within the Trial of Eczema allergy Screening Tests (TEST) feasibility trial.听锘� 听叠惭闯 Open. 2020;10(11):e041229. doi:
14.
Ameen 听M锘�, Meller 听S锘�, Pinter 听A锘�, Shear 听NH锘�, Soria 听A锘�; (the BADEL Study Group). 听Perception and experience of biologic therapy in atopic dermatitis: a qualitative focus group study of physicians and patients in Europe and Canada.听锘� 听Dermatol Ther (Heidelb). 2021;11(6):2159-2177. doi:
15.
Aubert-Wastiaux 听H锘�, Moret 听L锘�, Le Rhun 听A锘�, 听et al. 听Topical corticosteroid phobia in atopic dermatitis: a study of its nature, origins and frequency.听锘� 听Br J Dermatol. 2011;165(4):808-814. doi:
16.
Bazen 听A锘�, Sevagamoorthy 听A锘�, Barg 听FK锘�, Takeshita 听J.锘匡豢 听417 Adherence to topical therapy for atopic dermatitis: barriers and facilitators.听锘� 听J Invest Dermatol. 2020;140(7):S54. doi:
17.
Boeri 听M锘�, Sutphin 听J锘�, Hauber 听B锘�, Cappelleri 听JC锘�, Romero 听W锘�, Di Bonaventura 听M锘�. 听Quantifying patient preferences for systemic atopic dermatitis treatments using a discrete-choice experiment.听锘� 听J Dermatolog Treat. 2022;33(3):1449-1458. doi:
18.
Burkhart 听CN锘�, Burkhart 听CG锘�. 听Pilot study of patient satisfaction with nonfluorinated topical steroids compared with a topical immunomodulator in atopiform dermatitis.听锘� 听Int J Dermatol. 2004;43(3):215-219. doi:
19.
Cadmus 听SD锘�, Sebastian 听KR锘�, Warren 听D锘�, 听et al. 听Efficacy and patient opinion of wet-wrap dressings using 0.1% triamcinolone acetonide ointment vs cream in the treatment of pediatric atopic dermatitis: a randomized split-body control study.听锘� 听Pediatr Dermatol. 2019;36(4):437-441. doi:
20.
Capozza 听K锘�, Schwartz 听A锘�. 听Does it work and is it safe: parents鈥� perspectives on adherence to medication for atopic dermatitis.听锘� 听Pediatr Dermatol. 2020;37(1):58-61. doi:
21.
Charman 听CR锘�, Morris 听AD锘�, Williams 听HC锘�. 听Topical corticosteroid phobia in patients with atopic eczema.听锘� 听Br J Dermatol. 2000;142(5):931-936. doi:
22.
Djokic-Gallagher 听J锘�, Rosher 听P锘�, Oliveira 听G锘�, Walker 听J锘�. 听A double-blind, randomised study comparing the skin hydration and acceptability of two emollient products in atopic eczema patients with dry skin.听锘� 听Dermatol Ther (Heidelb). 2017;7(3):397-406. doi:
23.
Draelos 听ZD锘�. 听A clinical evaluation of the comparable efficacy of hyaluronic acid-based foam and ceramide-containing emulsion cream in the treatment of mild-to-moderate atopic dermatitis.听锘� 听J Cosmet Dermatol. 2011;10(3):185-188. doi:
24.
Ervin 听C锘�, Crawford 听R锘�, Evans 听E锘�, 听et al. 听Patient and caregiver preferences on treatment attributes for atopic dermatitis.听锘� 听J Dermatolog Treat. 2022;33(4):2225-2233. doi:
25.
Fenerty 听SD锘�, O鈥橬eill 听JL锘�, Gustafson 听CJ锘�, Feldman 听SR锘�. 听Maternal adherence factors in the treatment of pediatric atopic dermatitis.听锘� 听JAMA Dermatol. 2013;149(2):229-231. doi:
26.
Fukaya 听M锘�. 听Why do patients with atopic dermatitis refuse to apply topical corticosteroids?听锘� 听顿别谤尘补迟辞濒辞驳测. 2000;201(3):242-245. doi:
27.
Gerner 听T锘�, Haugaard 听JH锘�, Vestergaard 听C锘�, 听et al. 听Healthcare utilization in Danish children with atopic dermatitis and parental topical corticosteroid phobia.听锘� 听Pediatr Allergy Immunol. 2021;32(2):331-341. doi:
28.
Ghio 听D锘�, Muller 听I锘�, Greenwell 听K锘�, 听et al. 听鈥業t鈥檚 like the bad guy in a movie who just doesn鈥檛 die:鈥� a qualitative exploration of young people鈥檚 adaptation to eczema and implications for self-care.听锘� 听Br J Dermatol. 2020;182(1):112-118. doi:
29.
Gollnick 听H锘�, Luger 听T锘�, Freytag 听S锘�, Br盲utigam 听M锘�; STABIEL study group. 听StabiEL: stabilization of skin condition with Elidel鈥攁 patients鈥� satisfaction observational study addressing the treatment, with pimecrolimus cream, of atopic dermatitis pretreated with topical corticosteroid.听锘� 听J Eur Acad Dermatol Venereol. 2008;22(11):1319-1325. doi:
30.
Gore 听C锘�, Johnson 听RJ锘�, Caress 听AL锘�, Woodcock 听A锘�, Custovic 听A锘�. 听The information needs and preferred roles in treatment decision-making of parents caring for infants with atopic dermatitis: a qualitative study.听锘� 听础濒濒别谤驳测. 2005;60(7):938-943. doi:
31.
Greenwell 听K锘�, Ghio 听D锘�, Muller 听I锘�, 听et al. 听Taking charge of eczema self-management: a qualitative interview study with young people with eczema.听锘� 听叠惭闯 Open. 2021;11(1):e044005. doi:
32.
Hon 听KLE锘�, Kam 听WYC锘�, Leung 听TF锘�, 听et al. 听Steroid fears in children with eczema.听锘� 听Acta Paediatr. 2006;95(11):1451-1455. doi:
33.
Hon 听KLE锘�, Wang 听SS锘�, Pong 听NH锘�, Leung 听TF锘�. 听The ideal moisturizer: a survey of parental expectations and practice in childhood-onset eczema.听锘� 听J Dermatolog Treat. 2013;24(1):7-12. doi:
34.
Howells 听LM锘�, Chalmers 听JR锘�, Cowdell 听F锘�, Ratib 听S锘�, Santer 听M锘�, Thomas 听KS锘�. 听鈥榃hen it goes back to my normal I suppose鈥�: a qualitative study using online focus groups to explore perceptions of 鈥榗ontrol鈥� among people with eczema and parents of children with eczema in the UK.听锘� 听叠惭闯 Open. 2017;7(11):e017731. doi:
35.
Howells 听L锘�, Thomas 听KS锘�, Sears 听AV锘�, 听et al; Long-term control of eczema working group for the HOME initiative. 听Defining and measuring 鈥榚czema control鈥�: an international qualitative study to explore the views of those living with and treating atopic eczema.听锘� 听J Eur Acad Dermatol Venereol. 2019;33(6):1124-1132. doi:
36.
Joergensen 听KM锘�, Jemec 听GBE锘�. 听Use of moisturizers among Danish atopic dermatitis patients鈥攚hich perceived product characteristics associate with long-term adherence?听锘� 听J Dermatolog Treat. 2018;29(2):116-122. doi:
37.
Johnson 听MC锘�, Heron 听CE锘�, Feldman 听SR锘�. 听Caregiver preferences for the treatment of childhood atopic dermatitis.听锘� 听J Cutan Med Surg. 2021;25(3):336-338. doi:
38.
Johnston 听GA锘�, Bilbao 听RM锘�, Graham-Brown 听RA锘�. 听The use of complementary medicine in children with atopic dermatitis in secondary care in Leicester.听锘� 听Br J Dermatol. 2003;149(3):566-571. doi:
39.
Jung 听HJ锘�, Bae 听JY锘�, Kim 听JE锘�, 听et al. 听Survey of disease awareness, treatment behavior and treatment satisfaction in patients with atopic dermatitis in Korea: a multicenter study.听锘� 听J Dermatol. 2018;45(10):1172-1180. doi:
40.
Kamei 听K锘�, Hirose 听T锘�, Yoshii 听N锘�, Tanaka 听A锘�. 听Burden of illness, medication adherence, and unmet medical needs in Japanese patients with atopic dermatitis: a retrospective analysis of a cross-sectional questionnaire survey.听锘� 听J Dermatol. 2021;48(10):1491-1498. doi:
41.
Kosse 听RC锘�, Bouvy 听ML锘�, Daanen 听M锘�, de Vries 听TW锘�, Koster 听ES锘�. 听Adolescents鈥� perspectives on atopic dermatitis treatment-experiences, preferences, and beliefs.听锘� 听JAMA Dermatol. 2018;154(7):824-827. doi:
42.
Koster 听ES锘�, Philbert 听D锘�, Wagelaar 听KR锘�, Galle 听S锘�, Bouvy 听ML锘�. 听Optimizing pharmaceutical care for pediatric patients with dermatitis: perspectives of parents and pharmacy staff.听锘� 听Int J Clin Pharm. 2019;41(3):711-718. doi:
43.
Kunkiel 听K锘�, Natka艅ska 听A锘�, N臋dzi 听M锘�, Zawadzka-Krajewska 听A锘�, Feleszko 听W锘�. 听Patients鈥� preferences of leave-on emollients: a survey on patients with atopic dermatitis.听锘� 听J Dermatolog Treat. 2022;33(2):1143-1145. doi:
44.
Kurtti 听A锘�, Jagdeo 听J锘�. 听Analysis of Reddit reveals atopic dermatitis patient questions.听锘� 听J Drugs Dermatol. 2021;20(6):653-658. doi:
45.
Lee 听JY锘�, Her 听Y锘�, Kim 听CW锘�, Kim 听SS锘�. 听Topical corticosteroid phobia among parents of children with atopic eczema in Korea.听锘� 听Ann Dermatol. 2015;27(5):499-506. doi:
46.
Rhun 听AL锘�, Wastiaux 听HA锘�, Moret 听L锘�, 听et al. 听Fears regarding the use of topical corticosteroids in atopic dermatitis: looking at the coping strategies and the role of health care providers: a qualitative study.听锘� 听Educ Ther Patient/听Ther Patient Educ. 2015;7(2):20102. doi:
47.
Li 听Y锘�, Han 听T锘�, Li 听W锘�, Li 听Y锘�, Guo 听X锘�, Zheng 听L锘�. 听Awareness of and phobias about topical corticosteroids in parents of infants with eczema in Hangzhou, China.听锘� 听Pediatr Dermatol. 2018;35(4):463-467. doi:
48.
Lundin 听S锘�, Jonsson 听M锘�, Wahlgren 听C锘�, Johansson 听E锘�, Bergstrom 听A锘�, Kull 听I锘�. 听鈥淵ou try to take as little as possible鈥濃�攁 qualitative study of young adults with eczema recruited from the population-based birth cohort (BAMSE).听锘� 听础濒濒别谤驳测. 2019;74(S106):130-331.
49.
Lundin 听S锘�, Jonsson 听M锘�, Wahlgren 听CF锘�, Johansson 听E锘�, Bergstrom 听A锘�, Kull 听I锘�. 听Young adults鈥� perceptions of living with atopic dermatitis in relation to the concept of self-management: a qualitative study.听锘� 听叠惭闯 Open. 2021;11(6):e044777. doi:
50.
Maghen 听P锘�, Unrue 听EL锘�, Oussedik 听E锘�, Cline 听A锘�, Cardwell 听LA锘�, Feldman 听SR锘�. 听Regardless of how risks are framed, patients seem hesitant to use topical steroids for atopic dermatitis.听锘� 听Br J Dermatol. 2019;181(4):842-844. doi:
51.
McAlister 听RO锘�, Tofte 听SJ锘�, Doyle 听JJ锘�, Jackson 听A锘�, Hanifin 听JM锘�. 听Patient and physician perspectives vary on atopic dermatitis.听锘� 听颁耻迟颈蝉. 2002;69(6):461-466.
52.
Noerreslet 听M锘�, Jemec 听GBE锘�, Traulsen 听JM锘�. 听Involuntary autonomy: patients鈥� perceptions of physicians, conventional medicines and risks in the management of atopic dermatitis.听锘� 听Soc Sci Med. 2009;69(9):1409-1415. doi:
53.
N酶rreslet 听M锘�, Bissell 听P锘�, Traulsen 听JM锘�. 听From consumerism to active dependence: patterns of medicines use and treatment decisions among patients with atopic dermatitis.听锘� 听Health (London). 2010;14(1):91-106. doi:
54.
O鈥機onnor 听C锘�, Dhonncha 听EN锘�, Murphy 听M锘�. 听鈥淗is first word was 鈥榗ream鈥�:鈥� the burden of treatment in pediatric atopic dermatitis鈥攁 mixed methods study.听锘� 听Dermatol Ther. 2022;35(3):e15273. doi:
55.
Onumah 听N锘�, Kircik 听L锘�. 听Pimecrolimus cream and tacrolimus ointment in the treatment of atopic dermatitis: a pilot study on patient preference.听锘� 听J Drugs Dermatol. 2013;12(10):1145-1148.
56.
Okubo 听Y锘�, Ho 听KA锘�, Fifer 听S锘�, Fujita 听H锘�, Oki 听Y锘�, Taguchi 听Y锘�. 听Patient and physician preferences for atopic dermatitis injection treatments in Japan.听锘� 听J Dermatolog Treat. 2020;31(8):821-830. doi:
57.
Paller 听AS锘�, McAlister 听RO锘�, Doyle 听JJ锘�, Jackson 听A锘�. 听Perceptions of physicians and pediatric patients about atopic dermatitis, its impact, and its treatment.听锘� 听Clin Pediatr (Phila). 2002;41(5):323-332. doi:
58.
Powell 听K锘�, Le Roux 听E锘�, Banks 听J锘�, Ridd 听MJ锘�. 听GP and parent dissonance about the assessment and treatment of childhood eczema in primary care: a qualitative study.听锘� 听叠惭闯 Open. 2018;8(2):e019633. doi:
59.
Retzler 听J锘�, Smith 听A锘�, Reaney 听M锘�, Rout 听R锘�, Hudson 听R锘�. 听Process utilities for topical treatment in atopic dermatitis.听锘� 听Qual Life Res. 2019;28(9):2373-2381. doi:
60.
Roh 听NK锘�, Han 听SH锘�, Kim 听MJ锘�, 听et al. 听Awareness of atopic dermatitis and attitudes toward different types of medical institutions for its treatment among adult patients and the parents of pediatric patients: a survey of 500 participants.听锘� 听Ann Dermatol. 2016;28(6):725-732. doi:
61.
Santer 听M锘�, Muller 听I锘�, Yardley 听L锘�, Lewis-Jones 听S锘�, Ersser 听S锘�, Little 听P锘�. 听Parents鈥� and carers鈥� views about emollients for childhood eczema: qualitative interview study.听锘� 听叠惭闯 Open. 2016;6(8):e011887. doi:
62.
Santer 听M锘�, Burgess 听H锘�, Yardley 听L锘�, 听et al. 听Experiences of carers managing childhood eczema and their views on its treatment: a qualitative study.听锘� 听Br J Gen Pract. 2012;62(597):e261-e267. doi:
63.
Santer 听M锘�, Burgess 听H锘�, Yardley 听L锘�, 听et al. 听Managing childhood eczema: qualitative study exploring carers鈥� experiences of barriers and facilitators to treatment adherence.听锘� 听J Adv Nurs. 2013;69(11):2493-2501. doi:
64.
Schmitt 听J锘�, Cs枚t枚nyi 听F锘�, Bauer 听A锘�, Meurer 听M锘�. 听Determinants of treatment goals and satisfaction of patients with atopic eczema.听锘� 听J Dtsch Dermatol Ges. 2008;6(6):458-465. doi:
65.
Smith 听SD锘�, Hong 听E锘�, Fearns 听S锘�, Blaszczynski 听A锘�, Fischer 听G锘�. 听Corticosteroid phobia and other confounders in the treatment of childhood atopic dermatitis explored using parent focus groups.听锘� 听Australas J Dermatol. 2010;51(3):168-174. doi:
66.
Steinke 听S锘�, Langenbruch 听A锘�, St盲nder 听S锘�, Franzke 听N锘�, Augustin 听M锘�. 听Therapeutic benefits in atopic dermatitis care from the patients鈥� perspective: results of the German national health care study 鈥楢topic Health鈥�.听锘� 听顿别谤尘补迟辞濒辞驳测. 2014;228(4):350-359. doi:
67.
Teasdale 听EJ锘�, Muller 听I锘�, Santer 听M锘�. 听Carers鈥� views of topical corticosteroid use in childhood eczema: a qualitative study of online discussion forums.听锘� 听Br J Dermatol. 2017;176(6):1500-1507. doi:
68.
Thomas 听C锘�, Raibouaa 听A锘�, Wollenberg 听A锘�, 听et al. 听PMU105 Patient preferences for systemic atopic dermatitis treatments in the UK, France and Spain: a discrete choice experiment.听锘� 听Value Health. 2020;23:S621. doi:
69.
Torrelo 听A锘�, Ortiz 听J锘�, Alomar 听A锘�, Ros 听S锘�, Prieto 听M锘�, Cuervo 听J锘�. 听Atopic dermatitis: impact on quality of life and patients鈥� attitudes toward its management.听锘� 听Eur J Dermatol. 2012;22(1):97-105. doi:
70.
Veenje 听S锘�, Osinga 听H锘�, Antonescu 听I锘�, Bos 听B锘�, de Vries 听TW锘�. 听Focus group parental opinions regarding treatment with topical corticosteroids on children with atopic dermatitis.听锘� 听Allergol Immunopathol (Madr). 2019;47(2):166-171. doi:
71.
Wilson 听F锘�, Harnik 听E锘�, Gore 听C锘�. 听1745 Exploring parental understanding and views on topical corticosteroids (TCS) and TCS labelling in paediatric atopic dermatitis.听锘� 听础濒濒别谤驳测. 2020;75(S109):568-610.
72.
Zuberbier 听T锘�, Orlow 听SJ锘�, Paller 听AS锘�, 听et al. 听Patient perspectives on the management of atopic dermatitis.听锘� 听J Allergy Clin Immunol. 2006;118(1):226-232. doi:
73.
Zeichner 听J锘�, Feldman 听S锘�, Ervin 听C锘�, Crawford 听R锘�, Evans 听E锘�, Zielinski 听M锘�. 听26652 Patient and caregiver perspectives on treatment attributes for atopic dermatitis.听锘� 听J Am Acad Dermatol. 2021;85(3):AB111. doi:
74.
Augustin 听M锘�, Langenbruch 听A锘�, Blome 听C锘�, 听et al. 听Characterizing treatment-related patient needs in atopic eczema: insights for personalized goal orientation.听锘� 听J Eur Acad Dermatol Venereol. 2020;34(1):142-152. doi:
75.
Xie 听F锘�, Zhou 听T锘�. 听Industry sponsorship bias in cost effectiveness analysis: registry based analysis.听锘� 听叠惭闯. 2022;377:e069573. doi:
This Issue
Views 3,097
View Metrics
Review
January 25, 2023

Values and Preferences of Patients and Caregivers Regarding Treatment of Atopic Dermatitis (Eczema): A Systematic Review

Keon Andre听Maleki-Yazdi,听MD, MSc1; Anja Fog听Heen,听MD2; Irene X.听Zhao,听BHSc1; et al Gordon H.听Guyatt,听MD, MSc, OC1,3; Erica A.听Suzumura,听MSc4; 狈颈尘补听惭补办丑诲补尘颈,听惭顿1; 尝颈苍补听颁丑别苍,听叠厂肠5; 罢辞苍测补听奥颈苍诲别谤蝉,听惭叠础6; Kathryn E.听Wheeler,听MD7; 闯耻濒颈别听奥补苍驳,听惭顿8; Jonathan听Spergel,听MD, PhD9; Jonathan I.听Silverberg,听MD, MPH, PhD10; Peck Y.听Ong,听MD11; 惭辞苍颈肠补听翱鈥橞谤颈别苍,听惭叠厂12; Stephen A.听Martin,听MD, EdM13; Peter A.听Lio,听MD14; Mary Laura听Lind,听PhD15; 闯别苍苍颈蹿别谤听尝别叠辞惫颈诲驳别,听笔丑顿16; Elaine听Kim,听BScPhrm, RPh17; 闯辞别测听贬耻测苍丑,听惭笔罢18; Matthew听Greenhawt,听MD, MBA, MSc19; Winfred T.听Frazier,听MD, MPH20; 碍补迟丑测听贰濒濒颈蝉辞苍,听惭贰诲21; 碍辞谤别测听颁补辫辞锄锄补,听惭笔贬22; Anna听De Benedetto,听MD23; 惭补谤办听叠辞驳耻苍颈别飞颈肠锄,听惭顿19,24; Wendy Smith听Begolka,听MBS25; Rachel Netahe听Asiniwasis,听MD, MSc26; Lynda C.听Schneider,听MD16; Derek K.听Chu,听MD, PhD1,3,27
Author Affiliations Article Information
  • 1Department of Medicine, McMaster University, Hamilton, Canada
  • 2Department of Medicine, Lovisenberg Diaconal Hospital, Oslo, Norway
  • 3Department of Health Research Methods, Evidence & Impact, McMaster University, Hamilton, Canada
  • 4Department of Preventive Medicine, Faculdade de Medicina Universidade de Sao Paulo, Sao Paulo, Brazil
  • 5Faculty of Medicine, University of Ottawa, Ontario, Canada
  • 6Allergy & Asthma Network, Vienna, Virginia
  • 7Department of Pediatrics, University of Florida, Gainesville
  • 8Icahn School of Medicine at Mount Sinai, New York City, New York
  • 9Division of Allergy and Immunology, Children鈥檚 Hospital of Philadelphia, Department of Pediatrics鈥揚erelman School of Medicine at University of Pennsylvania, Philadelphia
  • 10Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC
  • 11Children鈥檚 Hospital Los Angeles, University of Southern California, Los Angeles
  • 12Tufts University School of Medicine, Boston, Massachusetts
  • 13University of Massachusetts Chan Medical School, Worcester
  • 14Northwestern University Feinberg School of Medicine, Chicago, Illinois
  • 15School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe
  • 16Boston Children鈥檚 Hospital, Harvard Medical School, Boston, Massachusetts
  • 17Toronto, Ontario
  • 18Orthopedic Neurological Rehabilitation, Northridge, California
  • 19University of Colorado School of Medicine, Aurora
  • 20Department of Family Medicine, UPMC St Margaret, Pittsburgh, Pennsylvania
  • 21Westerville, Ohio
  • 22Global Parents for Eczema Research, California
  • 23Department of Dermatology; University of Rochester Medical Center, Rochester, New York
  • 24National Jewish Health, Denver, Colorado
  • 25National Eczema Association, Novato, California
  • 26Origins Dermatology Centre, University of Saskatchewan, Regina, Saskatchewan, Canada
  • 27The Research Institute of St Joe's Hamilton, Hamilton, Canada
JAMA Dermatol. 2023;159(3):320-330. doi:10.1001/jamadermatol.2022.6045
visual abstract icon
Visual
Abstract
 editorial comment icon
Editorial
Comment
 related articles icon
Related
Articles
 author interview icon
Interviews
 multimedia icon
Multimedia
 audio icon
Listen to
this article
Key Points

Question听 What do patients and caregivers value when choosing treatments for atopic dermatitis?

Findings听 In this systematic synthesis of 62 studies including 19鈥�442 participants, patients and caregivers preferred avoiding adverse effects and valued treatment approaches that relieve itching and burning, are minimally disruptive to daily activities, have limited visibility, and sparingly use topical corticosteroids. Some studies presented varied perspectives, and 18 were at high risk for industry sponsorship bias.

Meaning听 In the first systematic review to address patient values and preferences in the management of atopic dermatitis to our knowledge, 6 key themes that may inform optimal clinical care, practice guidelines, and future research have been identified.

Abstract

Importance听 Patient values and preferences can inform atopic dermatitis (AD) care. Systematic summaries of evidence addressing patient values and preferences have not previously been available.

Objective听 To inform American Academy of Allergy, Asthma & Immunology (AAAAI)/American College of Allergy, Asthma and Immunology (ACAAI) Joint Task Force on Practice Parameters AD guideline development, patient and caregiver values and preferences in the management of AD were systematically synthesized.

Evidence Review听 Paired reviewers independently screened MEDLINE, Embase, PsycINFO, and CINAHL databases from inception until March 20, 2022, for studies of patients with AD or their caregivers, eliciting values and preferences about treatment, rated risk of bias, and extracted data. Thematic and inductive content analysis to qualitatively synthesize the findings was used. Patients, caregivers, and clinical experts provided triangulation. The GRADE-CERQual (Grading of Recommendations Assessment, Development and Evaluation鈥揅onfidence in the Evidence from Reviews of Qualitative Research) informed rating of the quality of evidence.

Findings听 A total of 7780 studies were identified, of which 62 proved eligible (n鈥�=鈥�19鈥�442; median age across studies [range], 15 years [3-44]; 59% female participants). High certainty evidence showed that patients and caregivers preferred to start with nonmedical treatments and to step up therapy with increasing AD severity. Moderate certainty evidence showed that adverse effects from treatment were a substantial concern. Low certainty evidence showed that patients and caregivers preferred odorless treatments that are not visible and have a minimal effect on daily life. Patients valued treatments capable of relieving itching and burning skin and preferred to apply topical corticosteroids sparingly. Patients valued a strong patient-clinician relationship. Some studies presented varied perspectives and 18 were at high risk for industry sponsorship bias.

Conclusions and Relevance听 In the first systematic review to address patient values and preferences in management of AD to our knowledge, 6 key themes that may inform optimal clinical care, practice guidelines, and future research have been identified.

×
Access your subscriptions
Add or change institution
Free access to newly published articles
To register for email alerts, access free PDF, and more
Purchase access
Get full journal access for 1 year
Get unlimited access and a printable PDF ($40.00)鈥�
Sign in or create a free account
Rent this article from DeepDyve
Access your subscriptions
Add or change institution
Free access to newly published articles
To register for email alerts, access free PDF, and more
Purchase access
Get full journal access for 1 year
Get unlimited access and a printable PDF ($40.00)鈥�
Sign in or create a free account
Rent this article from DeepDyve
Sign in to access free PDF
Add or change institution
Free access to newly published articles
To register for email alerts, access free PDF, and more
Save your search
Free access to newly published articles
To register for email alerts, access free PDF, and more
Purchase access
Make a comment
Free access to newly published articles
To register for email alerts, access free PDF, and more
Create a personal account or sign in to:
  • Register for email alerts with links to free full-text articles
  • Access PDFs of free articles
  • Manage your interests
  • Save searches and receive search alerts
Privacy Policy