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Day

September 30, 2024
Brief Report

Cardiac Myosin Inhibition in Heart Failure With Normal and Supranormal Ejection Fraction: Primary Results of the EMBARK-HFpEF Trial

Abstract Full Text
JAMA Cardiol. Published online September 30, 2024. doi:10.1001/jamacardio.2024.3810

The EMBARK-HFpEF multicenter, open-label trial examines the effects of cardiac myosin inhibition with mavacamten in patients with heart failure with preserved ejection fraction with a left ventricular ejection fraction of 60% or greater.

September 27, 2024
Brief Report

Estimated Long-Term Benefits of Finerenone in Heart Failure: A Prespecified Secondary Analysis of the FINEARTS-HF Randomized Clinical Trial

Abstract Full Text
open access
JAMA Cardiol. Published online September 27, 2024. doi:10.1001/jamacardio.2024.3782

This prespecified analysis of the Finerenone Trial to Investigate the Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) randomized clinical trial investigates the long-term effects of treatment with the nonsteroidal mineralocorticoid receptor antagonist, finerenone, in patients with heart failure with mildly reduced or preserved ejection fraction.

September 25, 2024
From the Heart

The Cotton Plant

Abstract Full Text
JAMA Cardiol. Published online September 25, 2024. doi:10.1001/jamacardio.2024.2960

This essay describes the author’s experience when her father had cardiac arrest.

September 18, 2024
Comment & Response

Importance of Prolonged QRS Duration in Detecting Complete Conduction Block

Abstract Full Text
JAMA Cardiol. Published online September 18, 2024. doi:10.1001/jamacardio.2024.2963

Importance of Prolonged QRS Duration in Detecting Complete Conduction Block—Reply

Abstract Full Text
JAMA Cardiol. Published online September 18, 2024. doi:10.1001/jamacardio.2024.2966
September 2, 2024
Original Investigation

Lesion-Level Effects of LDL-C–Lowering Therapy in Patients With Acute Myocardial Infarction: A Post Hoc Analysis of the PACMAN-AMI Trial

Abstract Full Text
JAMA Cardiol. Published online September 2, 2024. doi:10.1001/jamacardio.2024.3200

This post hoc analysis of a randomized clinical trial analyzes imaging data for atheroma volume at the lesion level from patients who received intensive lipid-lowering therapy with alirocumab plus statin compared with a statin alone.

Invited Commentary

What We Have Learned About Reducing Low-Density Lipoprotein Cholesterol and Coronary Plaques

Abstract Full Text
JAMA Cardiol. Published online September 2, 2024. doi:10.1001/jamacardio.2024.3213
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