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October 30, 2024
Original Investigation

Outcomes of Balloon-Expandable Transcatheter Aortic Valve Replacement in Younger Patients in the Low-Risk Era

Abstract Full Text
open access
JAMA Cardiol. Published online October 30, 2024. doi:10.1001/jamacardio.2024.4237

This cohort study assesses characteristics and outcomes of younger patients undergoing transcatheter aortic valve replacement.

Validation of the Kansas City Cardiomyopathy Questionnaire in Patients With Tricuspid Regurgitation

Abstract Full Text
JAMA Cardiol. Published online October 30, 2024. doi:10.1001/jamacardio.2024.4266

This cohort study evaluates the psychometric properties of the Kansas City Cardiomyopathy Questionnaire in patients with tricuspid regurgitation using pooled data from 11 manufacturer-sponsored trials of transcatheter tricuspid valve interventions.

Invited Commentary

Measuring Health Status in Patients With Tricuspid Regurgitation

Abstract Full Text
JAMA Cardiol. Published online October 30, 2024. doi:10.1001/jamacardio.2024.4287
Editor's Note

TAVR in Young Patients With Aortic Stenosis: Appropriate Use or Indication Creep?

Abstract Full Text
JAMA Cardiol. Published online October 30, 2024. doi:10.1001/jamacardio.2024.4300
October 29, 2024
Original Investigation

Cerebral Embolic Protection by Geographic Region: A Post Hoc Analysis of the PROTECTED TAVR Randomized Clinical Trial

Abstract Full Text
open access
JAMA Cardiol. Published online October 29, 2024. doi:10.1001/jamacardio.2024.4278

This randomized clinical trial evaluates regional differences in the association between stroke outcomes and cerebral embolic protection.

October 27, 2024
Original Investigation

Microaxial Flow Pump Hemodynamic and Metabolic Effects in Infarct-Related Cardiogenic Shock: A Substudy of the DanGer Shock Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online October 27, 2024. doi:10.1001/jamacardio.2024.4197

This substudy of the Danish-German (DanGer) Shock randomized clinical trial investigates if the use of a microaxial flow pump reduces the need for pharmacological support and what the effects are on hemodynamics and lactate clearance in patients with ST-elevation myocardial infarction–induced cardiogenic shock.

Editorial

Evidence for Mechanical Circulatory Support in Cardiogenic Shock

Abstract Full Text
JAMA Cardiol. Published online October 27, 2024. doi:10.1001/jamacardio.2024.4225
October 23, 2024
Original Investigation

Utility of a Systolic Blood Pressure Polygenic Risk Score With Chlorthalidone Response

Abstract Full Text
JAMA Cardiol. Published online October 23, 2024. doi:10.1001/jamacardio.2024.3649

This genetic association study uses data from Black participants in the the Genetics of Hypertension Associated Treatments (GenHAT) study to investigate the ability of systolic blood pressure polygenic risk scores to predict antihypertensive treatment response and apparent treatment-resistant hypertension.

Editor's Note

Precision Medicine to Guide Blood Pressure Control?

Abstract Full Text
JAMA Cardiol. Published online October 23, 2024. doi:10.1001/jamacardio.2024.3662
October 16, 2024
Original Investigation

Coronary Revascularization Guided With Fractional Flow Reserve or Instantaneous Wave-Free Ratio: A 5-Year Follow-Up of the DEFINE FLAIR Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online October 16, 2024. doi:10.1001/jamacardio.2024.3314

This study compares long-term outcomes of instantaneous wave-free ratio and fractional flow reserve-based strategies to guide revascularization.

Trends in Transcatheter Aortic Valve Replacement Outcomes: Insights From the STS/ACC TVT Registry

Abstract Full Text
JAMA Cardiol. Published online October 16, 2024. doi:10.1001/jamacardio.2024.3453

This cohort study examines changes in risk-adjusted transcatheter aortic valve replacement (TAVR) outcomes from 2019 to 2022 using data from the Society of Thoracic Surgeons (STS)/American College of Cardiology (ACC) Transcatheter Valve Therapies (TVT) Registry.

Viewpoint

Age-Stratified Risk Categories for Cardiovascular Disease Prevention Therapies

Abstract Full Text
JAMA Cardiol. Published online October 16, 2024. doi:10.1001/jamacardio.2024.3544

This Viewpoint describes age-specific risk thresholds for cardiovascular disease prevention therapies.

Review

Aortic Stenosis, Heart Failure, and Aortic Valve Replacement

Abstract Full Text
has active quiz
JAMA Cardiol. Published online October 16, 2024. doi:10.1001/jamacardio.2024.3486

This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.

Comment & Response

Influenza Vaccine in High-Risk Cardiovascular Diseases—Define the Target

Abstract Full Text
JAMA Cardiol. Published online October 16, 2024. doi:10.1001/jamacardio.2024.3466

Influenza Vaccine in High-Risk Cardiovascular Diseases—Define the Target—Reply

Abstract Full Text
JAMA Cardiol. Published online October 16, 2024. doi:10.1001/jamacardio.2024.3463
Editor's Note

Parsing Signal vs Noise—Secondary Analyses of RCTs

Abstract Full Text
JAMA Cardiol. Published online October 16, 2024. doi:10.1001/jamacardio.2024.3329
October 9, 2024
Original Investigation

Short-Term Dual Antiplatelet Therapy After Drug-Eluting Stenting in Patients With Acute Coronary Syndromes: A Systematic Review and Network Meta-Analysis

Abstract Full Text
JAMA Cardiol. Published online October 9, 2024. doi:10.1001/jamacardio.2024.3216

This systematic review and network meta-analysis investigates the optimal duration of dual antiplatelet therapy in patients with acute coronary syndromes (ACS) undergoing percutaneous coronary intervention with drug-eluting stents.

Transcatheter Aortic Valve Implantation by Valve Type in Women With Small Annuli: Results From the SMART Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online October 9, 2024. doi:10.1001/jamacardio.2024.3241

This prespecified secondary analysis of a randomized clinical trial evaluates clinical and hemodynamic outcomes by valve type in transcatheter aortic valve replacement among women with small aortic annuli.

Cardiovascular Images

Ventricular Septal Rupture After ST-Segment Elevation Myocardial Infarction

Abstract Full Text
has active quiz has multimedia
JAMA Cardiol. Published online October 9, 2024. doi:10.1001/jamacardio.2024.3308

This case report describes a diagnosis of ventricular septal rupture in a patient in his 70s after ST-segment elevation myocardial infarction (STEMI) due to right coronary artery occlusion.

Correction

Error in Figure 1

Abstract Full Text
free access
JAMA Cardiol. Published online October 9, 2024. doi:10.1001/jamacardio.2024.3703
October 2, 2024
Original Investigation

Amiodarone or Implantable Cardioverter-Defibrillator in Chagas Cardiomyopathy: The CHAGASICS Randomized Clinical Trial

Abstract Full Text
open access
JAMA Cardiol. Published online October 2, 2024. doi:10.1001/jamacardio.2024.3169

This randomized clinical trial assesses whether cardioverter-defibrillator implantation is more effective than amiodarone therapy for the primary prevention of all-cause mortality and secondary prevention of sudden cardiac death, hospitalization for heart failure, and use of a pacemaker among patients with chronic Chagas cardiomyopathy.

Endovascular Ablation of the Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: The REBALANCE-HF Randomized Clinical Trial

Abstract Full Text
JAMA Cardiol. Published online October 2, 2024. doi:10.1001/jamacardio.2024.2612

This randomized clinical trial investigates the feasibility, safety, and efficacy of endovascular right-sided splanchnic nerve ablation for volume management in heart failure with preserved ejection fraction (HFpEF).

Brief Report

Global Impact of Optimal Implementation of Guideline-Directed Medical Therapy in Heart Failure

Abstract Full Text
JAMA Cardiol. Published online October 2, 2024. doi:10.1001/jamacardio.2024.3023

This study examines the projected population-level benefit of optimal guideline-directed medical therapy use globally among patients with heart failure with reduced ejection fraction.

Comment & Response

Frailty in an Elderly Cohort With Myocardial Infarction and High Bleeding Risk

Abstract Full Text
JAMA Cardiol. Published online October 2, 2024. doi:10.1001/jamacardio.2024.3017

Frailty in an Elderly Cohort With Myocardial Infarction and High Bleeding Risk—Reply

Abstract Full Text
JAMA Cardiol. Published online October 2, 2024. doi:10.1001/jamacardio.2024.3020
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