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This cross-sectional study assesses national 30-day and 1-year outcomes of mitral valve surgery and defines the hospital- and surgeon-level volume-outcome associations for mitral valve repair or replacement in patients with primary mitral regurgitation.

This systematic review and meta-analysis examines the natural history of asymptomatic aortic stenosis and the association of early intervention with survival.

This cohort study evaluates the associations of elevated B-type natriuretic peptide levels after transcatheter aortic valve replacement (TAVR) and change in B-type natriuretic peptide levels between follow-up time points with risk of subsequent clinical outcomes.

This pooled analysis of data from 4 completed phase 3 randomized clinical trials assesses the efficacy and safety associated with administration of bempedoic acid vs placebo among patients with hypercholesterolemia and atherosclerotic cardiovascular disease with or without heterozygous familial hypercholesterolemia who were receiving statins and among patients with hypercholesterolemia and statin intolerance.

This secondary analysis of the randomized clinical ACCELERATE trial examines whether lipoprotein(a)-associated cardiovascular risk is modulated by systemic inflammation in optimally treated patients at high risk for cardiovascular disease.

This cohort study defines a molecular basis for cardiometabolic stress and assesses its associations with cardiovascular prognosis.

This cross-sectional study describes the characteristics associated with outpatient cardiac arrests and death during the coronavirus disease 2019 pandemic in New York City.