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October 2024 - July 1959

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Issue

July 2021, Vol 78, No. 7, Pages 693-796

Viewpoint

Psychiatry and Deaths of Despair

Abstract Full Text
JAMA Psychiatry. 2021;78(7):695-696. doi:10.1001/jamapsychiatry.2021.0256

This Viewpoint discusses how psychiatry is well positioned to define and measure despair.

Three Important Considerations for Studies Examining Pathophysiological Pathways in Psychiatric Illness: In-depth Phenotyping, Biological Assessment, and Causal Inferences

Abstract Full Text
JAMA Psychiatry. 2021;78(7):697-698. doi:10.1001/jamapsychiatry.2021.0022

This Viewpoint discusses the importance of in-depth phenotyping, biological assessment, and causal inferences in studying the etiology of psychiatric disorders.

A New Consensus Framework for Phenotyping and Treatment Selecting in Addiction and Obsessive-Compulsive–Related Disorders

Abstract Full Text
JAMA Psychiatry. 2021;78(7):699-700. doi:10.1001/jamapsychiatry.2021.0243

This Viewpoint assesses a consensus framework for phenotyping and treatment selecting in addiction and obsessive-compulsive–related disorders.

Moving Beyond Medications That Act at the μ Receptor in the Treatment of Opioid Use Disorder

Abstract Full Text
JAMA Psychiatry. 2021;78(7):701-702. doi:10.1001/jamapsychiatry.2021.0259

This Viewpoint discusses the potential use of non-μ treatments of opioid use disorder and provides an overview of considerations for the field as it moves to develop such agents.

Healing Ethno-Racial Trauma in Black Communities: Cultural Humility as a Driver of Innovation

Abstract Full Text
JAMA Psychiatry. 2021;78(7):703-704. doi:10.1001/jamapsychiatry.2021.0537

This Viewpoint invites decision-makers and innovators to emphasize cultural humility as a mechanism for promoting healing from ethno-racial trauma in Black communities and for developing health equity in the long term.

Original Investigation

Therapist-Guided Internet-Delivered Cognitive Behavioral Therapy vs Internet-Delivered Supportive Therapy for Children and Adolescents With Social Anxiety Disorder: A Randomized Clinical Trial

Abstract Full Text
open access has audio
JAMA Psychiatry. 2021;78(7):705-713. doi:10.1001/jamapsychiatry.2021.0469

This randomized clinical trial assesses the efficacy and cost-effectiveness of therapist-guided internet-delivered cognitive behavioral therapy for social anxiety disorder in youths compared with internet-delivered supportive therapy.

Effects of SlowMo, a Blended Digital Therapy Targeting Reasoning, on Paranoia Among People With Psychosis: A Randomized Clinical Trial

Abstract Full Text
open access
JAMA Psychiatry. 2021;78(7):714-725. doi:10.1001/jamapsychiatry.2021.0326

This randomized clinical trial investigates the effects and mechanisms of action of SlowMo, a digitally supported reasoning intervention, plus usual care compared with usual care only among individuals with clinical paranoia.

Racial/Ethnic Disparities in the Performance of Prediction Models for Death by Suicide After Mental Health Visits

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):726-734. doi:10.1001/jamapsychiatry.2021.0493

This diagnostic/prognostic study of outpatient mental health visits evaluates racial/ethnic differences in the performance of statistical models that predict suicide.

Family Genetic Risk Scores and the Genetic Architecture of Major Affective and Psychotic Disorders in a Swedish National Sample

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):735-743. doi:10.1001/jamapsychiatry.2021.0336

This national cohort study assesses whether family genetic risk scores, calculated for the entire Swedish population, can elucidate the genetic association between major affective and psychotic disorders and clarify the effect of genetic risk on important clinical features of disease.

Discriminating Heterogeneous Trajectories of Resilience and Depression After Major Life Stressors Using Polygenic Scores

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):744-752. doi:10.1001/jamapsychiatry.2021.0228

This cohort study examines the use of combined polygenic scores using deep neural networks in discriminating symptom trajectories in individuals following major life stressors.

Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):753-766. doi:10.1001/jamapsychiatry.2021.0638

This case-control study investigates baseline structural magnetic resonance imaging (MRI) differences between individuals at clinical high risk and healthy controls as well as between participants at clinical high risk who later developed a psychotic disorder and those who did not.

Cost-effectiveness of Treatments for Opioid Use Disorder

Abstract Full Text
free access has audio
JAMA Psychiatry. 2021;78(7):767-777. doi:10.1001/jamapsychiatry.2021.0247

This study evaluates the cost-effectiveness of medication-assisted treatment and treatment add-ons (eg, contingency management) for opioid use disorder.

Association of Multigenerational Family History of Depression With Lifetime Depressive and Other Psychiatric Disorders in Children: Results from the Adolescent Brain Cognitive Development (ABCD) Study

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):778-787. doi:10.1001/jamapsychiatry.2021.0350

This secondary analysis of the Adolescent Brain Cognitive Development study examines the association of multigenerational family history of depression with lifetime depressive disorders and other psychopathology in children.

Neuroscience and Psychiatry

Neuromelanin-Sensitive Magnetic Resonance Imaging as a Proxy Marker for Catecholamine Function in Psychiatry

Abstract Full Text
JAMA Psychiatry. 2021;78(7):788-789. doi:10.1001/jamapsychiatry.2021.0927

This article describes the use of neuromelanin-sensitive magnetic resonance imaging for the monitoring of the catecholamine neuromodulators dopamine and norepinephrine in the brains of individuals with mental illness.

Research Letter

Neural Correlates of Affective Benefit From Real-life Social Contact and Implications for Psychiatric Resilience

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):790-792. doi:10.1001/jamapsychiatry.2021.0560

This cohort study examines the association of daily-life social affective benefit with brain structure and psychiatric risk and resilience measures in 2 independent community-based samples.

Polygenic Liability and Recurrence of Depression in Patients With First-Onset Depression Treated in Hospital-Based Settings

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):792-795. doi:10.1001/jamapsychiatry.2021.0701

This cohort study examines the association of polygenic risk score for major depression with risk of recurrence in individuals diagnosed with unipolar depression in hospital-based settings and estimates the absolute risk of recurrence based on polygenic risk.

Comment & Response

Improving the Assessment of COVID-19–Associated Posttraumatic Stress Disorder

Abstract Full Text
JAMA Psychiatry. 2021;78(7):795. doi:10.1001/jamapsychiatry.2021.1123

Improving the Assessment of COVID-19–Associated Posttraumatic Stress Disorder—Reply

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):795-796. doi:10.1001/jamapsychiatry.2021.1126
Correction

Errors in Text

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):796. doi:10.1001/jamapsychiatry.2021.0531

Error in Title and Text

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):796. doi:10.1001/jamapsychiatry.2021.1113
JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(7):693. doi:10.1001/jamapsychiatry.2020.3140
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