Nursing home (NH) residents are at excess risks of atrial fibrillation (AF)–related stroke and oral anticoagulant (OAC)–related bleeding. In older adults (aged ≥65 years) with multimorbidity and AF, clinicians may select aspirin rather than OAC for stroke prophylaxis to limit bleeding risk. However, antiplatelets are unequivocally ineffective for preventing cardioembolic stroke in AF,1 while increasing bleeding risk.2 In another common scenario, patients with AF treated with OAC may also be prescribed an antiplatelet without indication. Studies reported prevalence of OAC use in long-stay NH residents with AF of 30% to 35%,3,4 but these claims-based studies were unable to capture aspirin use. In this study, we estimate the use of OAC and antiplatelets, including aspirin, among residents with AF.