To the Editor.—Ìý Transfer factor (TF) improves cellular immunity¹ and is useful in treating viral illnesses. We report the case of a patient with Guillain-Barré syndrome that was treated with TF.

Report of a Case.—Ìý A 50-year-old man, a general surgeon, had nausea, vomiting, and diarrhea on Dec 3, 1977. On Dec 10, he experienced cramps and weakness in his legs. During the following week, he noticed numbness and weakness in all four limbs. He needed help to stand and could not walk alone. The spinal fluid protein level was increased (123 mg/dL), with normal chloride and glucose levels. There were no cells. Blood glucose and BUN levels, a chest roentgenogram, and a cholecystogram were normal, as were the results of a VDRL test and a gastrointestinal x-ray film series. A diagnosis of Guillain-Barré syndrome was made.He was given a total of five injections of methylprednisolone sodium succinate