Patients with localized prostate cancer who pursued active treatment, especially surgery, were more likely to express regret than those who chose active surveillance, researchers reported in JAMA Oncology.
The study鈥檚 authors analyzed treatment-related regret among 2072 men 5 years after they received radical prostatectomy, radiotherapy, or active surveillance. Among patients who chose surveillance, 7% reported regret compared with 11% of those who chose radiotherapy and 16% of those who chose surgery. After adjusting for baseline differences, men who underwent surgery but not radiotherapy were significantly more likely to experience regret than those who received active surveillance.