Explore the latest in head and neck cancers, including advances in understanding epidemiology, risk factors, staging, and management.
This quality improvement study evaluates the experiences of patients with head and neck cancer and next of kin with a hybrid palliative care pathway.
This Viewpoint describes how frailty assessments should be incorporated into surgical oncology decision-making for older adults with head and neck cancer.
This Viewpoint discusses prophylactic antidepressant use for depression prevention in patients with head and neck cancer and the need to include recommendations for depression prevention in guidelines for these patients.
This cohort study compares the prevalence of depression between adult patients with head and neck cancer and those with other cancers in the US.
This cohort study aims to refine the understanding of human papillomavirus−positive oropharyngeal squamous cell carcinoma recurrence and inform optimal imaging surveillance strategies.
This diagnostic study examines the formation of the ninth version of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC) tumor-node-metastasis (TNM) staging system.
This meta-analysis reviews pooled data from studies of frozen section analysis used to evaluate sentinel nodes in patients with cT1-T2 N0 oral squamous cell cancer.
This cohort study explores whether the different energy sources used and differing surgical philosophy of transoral robotic surgery and laser microsurgery are associated with postoperative early swallowing function, feeding tube use, and specific factors related to quality of life among patients with human papillovirus–positive oropharyngeal squamous cell carcinoma.
This case series study evaluates the safety and outcomes of stent-graft placement for treatment of carotid blowout syndrome in patients with head and neck cancer.
This cohort study assesses whether tumor hypoxia on 18F-fluoromisonidazole positron emission tomography (PET) scan is associated with distant metastasis among patients with head and neck squamous cell carcinoma (SCC).
This prospective case-control study nested in 3 large, well-established, prospective US cohorts examines whether the oral bacterial and fungal microbiome is associated with subsequent head and neck squamous cell cancer risk.
This cohort study examines key determinants of prognosis in patients with nodal metastatic head and neck cutaneous squamous cell carcinoma.
This diagnostic study assesses the performance metrics of tumor tissue–modified human papillomavirus (HPV) DNA testing for diagnosing oropharyngeal squamous cell carcinoma in patients with a lateral neck mass.
This economic evaluation assesses changes to patient out-of-pocket spending for oral cancer medications before and after the Inflation Reduction Act.
This cohort study evaluates the incidence of oropharynx cancer in patients with incidental asymmetric oropharynx positron emission tomography uptake.
This cohort study investigates survival in US patients receiving immune checkpoint inhibitor–based treatment for recurrent or metastatic head and neck squamous cell carcinoma (HNSCC), outcomes of treatment discontinuation vs continuation at 1 or 2 years, and outcomes after immunotherapy rechallenge.
This multi-institutional nonrandomized clinical trial testing a novel diagnostic/screening assay aims to determine whether soluble CD44 and total protein are useful for monitoring head and neck cancer recurrence, either used in a point-of-care test or as individual laboratory-based biomarkers.
This cohort study examines the clinical association between cannabis use and head and neck cancer.
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