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Comment & Response
February 16, 2022

Laparoscopic Gastrectomy for Locally Advanced Gastric Cancer

Author Affiliations
  • 1Digestive Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
JAMA Surg. 2022;157(6):545-546. doi:10.1001/jamasurg.2021.7582

To the Editor We read with great interest the article by Huang et al1 who updated the 5-year overall survival data from the Chinese Laparoscopic Gastrointestinal Surgical Study (CLASS-01) trial of laparoscopic vs open distal gastrectomy among patients with locally advanced gastric cancer (LAGC).

At 5 years, the overall survival rates were 72.6% in the laparoscopic distal gastrectomy (LDG) group and 76.3% in the open distal gastrectomy (ODG) group (log-rank P = .19). According to tumor stage, for patients with stage I tumors, the rates of 5-year overall survival were 90.0% in the LDG group vs 88.5% in the ODG group; for patients with stage II tumors, 79.1% in the LDG group vs 84.5% in the ODG group; and for patients with stage III tumors, 58.6% in the LDG group vs 59.5% in the ODG group.1

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