Magdalena Janecka, PhD; Arad Kodesh, MD; Stephen Z. Levine, PhD; et al.
free access
has audio
JAMA Psychiatry. 2018;75(12):1217-1224. doi:10.1001/jamapsychiatry.2018.2728
This population-based case-control study investigates the association of prenatal exposure to medications that interfere with different neurotransmitter systems with the risk of autism spectrum disorders in offspring in a birth cohort of individuals with and without the disorder.
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Podcast:
Association of Autism Spectrum Disorder with Prenatal Exposure to Medication Affecting Neurotransmitter Systems
Andrea L. Roberts, PhD; Laura D. Kubzansky, PhD; Susan Malspeis, MS; et al.
free access
JAMA Psychiatry. 2018;75(12):1225-1233. doi:10.1001/jamapsychiatry.2018.2462
This longitudinal cohort study of nearly 200 000 women participating for 20 years in the Nurses’ Health Study and the Nurses’ Health Study II assesses whether an association exists between depression and risk of incident systemic lupus erythematosus.
Pirathiv Kugathasan, MSc; Henriette Thisted Horsdal, MSc, PhD; Jørgen Aagaard, MD, DMSc; et al.
free access
JAMA Psychiatry. 2018;75(12):1234-1240. doi:10.1001/jamapsychiatry.2018.2742
This study uses the Danish nationwide health care registries to investigate the association of secondary preventive cardiovascular treatment with all-cause mortality after myocardial infarction in patients with schizophrenia compared with those without schizophrenia.
Heather E. Acuff, PhD; Amelia Versace, MD; Michele A. Bertocci, PhD; et al.
free access
JAMA Psychiatry. 2018;75(12):1241-1251. doi:10.1001/jamapsychiatry.2018.2318
This cross-sectional, longitudinal study examines neuroimaging measures of emotion processing and regulation neural circuitries with symptoms of bipolar disorder in offspring of parents with bipolar disorder compared with offspring of parents with non–bipolar disroder psychopathologies and offspring of healthy parents.
Tara A. Niendam, PhD; Kimberly L. Ray, PhD; Ana-Maria Iosif, PhD; et al.
free access
JAMA Psychiatry. 2018;75(12):1252-1260. doi:10.1001/jamapsychiatry.2018.2538
This naturalistic functional magnetic resonance imaging study examines the association of age at onset and longitudinal course of prefrontal activity in youths with early-onset schizophrenia compared with age-matched healthy control individuals.
Qiang Wang, MD, PhD; Hei Man Wu, PhD; Weihua Yue, MD, PhD; et al.
open access
JAMA Psychiatry. 2018;75(12):1261-1269. doi:10.1001/jamapsychiatry.2018.3039
This randomized clinical trial examines genes and gene sets using exome sequencing technology to determine the genetic mechanism behind the responses to antipsychotic drugs prescribed to patients with schizophrenia.
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Invited Commentary
Successes and Challenges in Precision Medicine in Psychiatry
Edwin J. C. G. van den Oord, PhD; Robin F. Chan, PhD; Karolina A. Aberg, PhD
JAMA Psychiatry
Gregory P. Strauss, PhD; Alicia Nuñez, MPH; Anthony O. Ahmed, PhD; et al.
free access
JAMA Psychiatry. 2018;75(12):1271-1279. doi:10.1001/jamapsychiatry.2018.2475
This cross-sectional study used confirmatory factor analysis to evaluate the fit of 4 models regarding the latent structure of negative symptoms using confirmatory factor analysis in a population of outpatients with schizophrenia.