Sagnik Bhattacharyya, MBBS, MD, PhD; Robin Wilson, MBBS, MRCPsych; Elizabeth Appiah-Kusi, MSc; et al.
free access
JAMA Psychiatry. 2018;75(11):1107-1117. doi:10.1001/jamapsychiatry.2018.2309
This randomized clinical trial investigates the neurocognitive mechanisms that underlie the therapeutic effects of cannabidiol vs placebo in people at clinical high risk of psychosis.
Martin J. De Vita, MS; Dezarie Moskal, MS; Stephen A. Maisto, PhD; et al.
free access
has audio
JAMA Psychiatry. 2018;75(11):1118-1127. doi:10.1001/jamapsychiatry.2018.2503
This study examines findings from decades of published research to determine whether use of cannabinoid analgesia is associated with experimental pain relief among healthy adults.
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Podcast:
Association of Cannabinoid Administration With Experimental Pain in Healthy Adults
Ceri Price, MSc; Christina Dalman, PhD; Stanley Zammit, PhD; et al.
open access
JAMA Psychiatry. 2018;75(11):1128-1136. doi:10.1001/jamapsychiatry.2018.2233
This cohort study examines the association of residential mobility during childhood, adolescence, and adulthood with risk of developing nonaffective psychosis in young people in Sweden.
Mark Wade, PhD; Nathan A. Fox, PhD; Charles H. Zeanah, MD; et al.
free access
JAMA Psychiatry. 2018;75(11):1137-1145. doi:10.1001/jamapsychiatry.2018.2556
This randomized clinical trial examines trajectories of latent psychopathology factors—general, internalizing, and externalizing—among children reared in institutions and evaluates whether randomization to foster care is associated with reductions in psychopathology from middle childhood through adolescence.
Thomas Wolfers, MSc; Nhat Trung Doan, PhD; Tobias Kaufmann, PhD; et al.
free access
JAMA Psychiatry. 2018;75(11):1146-1155. doi:10.1001/jamapsychiatry.2018.2467
This study uses normative modeling to map regional brain alterations to examine brain structural heterogeneity in adults with schizophrenia and bipolar disorder vs healthy individuals.
Nikolaos Koutsouleris, MD; Lana Kambeitz-Ilankovic, PhD; Stephan Ruhrmann, MD; et al.
free access
JAMA Psychiatry. 2018;75(11):1156-1172. doi:10.1001/jamapsychiatry.2018.2165
This cohort study assesses whether machine learning based on clinical and imaging data can determine predictors associated with social and role functioning in patients with recent-onset depression or in clinical high-risk states for psychosis.
Alexandra Rouquette, MD, PhD; Jean-Baptiste Pingault, PhD; Eiko I. Fried, PhD; et al.
free access
JAMA Psychiatry. 2018;75(11):1173-1181. doi:10.1001/jamapsychiatry.2018.2119
This population-based network analysis examines the association between emotional and behavior symptoms demonstrated by elementary school girls and later diagnoses of anxiety disorder and depression in adolescence and early adulthood.
Kenneth S. Kendler, MD; Henrik Ohlsson, PhD; Abigail A. Fagan, PhD; et al.
free access
JAMA Psychiatry. 2018;75(11):1182-1188. doi:10.1001/jamapsychiatry.2018.2337
To clarify the nature of the association between adolescent academic achievement and drug abuse into middle adulthood, this study uses 2 methods for assessing associations in observational studies, instrumental variable (with month of birth as the instrument) and co-relative analyses, and long-term follow-up to assess data from 934 462 individuals born in Sweden between 1971 and 1982.
Jeffrey F. Scherrer, PhD; Joanne Salas, MPH; Patrick J. Lustman, PhD; et al.
free access
JAMA Psychiatry. 2018;75(11):1189-1198. doi:10.1001/jamapsychiatry.2018.2028
This cohort study assesses a veteran population with and without posttraumatic stress disorder (PTSD) to determine if obesity can account for the increased risk of incident type 2 diabetes in patients with PTSD.