Lars Tanum, MD, DMSci; Kristin Klemmetsby Solli, MSc; Zill-e-Huma Latif, MD; et al.
free access
JAMA Psychiatry. 2017;74(12):1197-1205. doi:10.1001/jamapsychiatry.2017.3206
This randomized clinical trial compares the effectiveness of extended-release naltrexone with that of buprenorphine-naloxone in maintaining short-term abstinence from heroin and other illicit substances.
Sameer Jauhar, MRCPsych; Matthew M. Nour, MRCPsych; Mattia Veronese, PhD; et al.
open access
JAMA Psychiatry. 2017;74(12):1206-1213. doi:10.1001/jamapsychiatry.2017.2943
This cross-sectional case-control positron emission tomographic study tests whether dopamine synthesis capacity is elevated in bipolar disorder with psychosis and how this compares with schizophrenia and matched controls.
Yuri Milaneschi, PhD; Femke Lamers, PhD; Wouter J. Peyrot, MD, PhD; et al.
free access
JAMA Psychiatry. 2017;74(12):1214-1225. doi:10.1001/jamapsychiatry.2017.3016
This consortium study of multiple data sets assesses whether patients with major depressive disorder had different degrees of genetic overlap with obesity-related traits.
Fernando Pires Hartwig, MSc; Maria Carolina Borges, PhD; Bernardo Lessa Horta, PhD; et al.
open access
JAMA Psychiatry. 2017;74(12):1226-1233. doi:10.1001/jamapsychiatry.2017.3191
This study uses mendelian randomization of candidate gene or genome-wide association studies to evaluate the association between inflammatory biomarkers and the risk of schizophrenia.
Hang Zhou, PhD; Renato Polimanti, PhD; Bao-Zhu Yang, PhD; et al.
free access
JAMA Psychiatry. 2017;74(12):1234-1241. doi:10.1001/jamapsychiatry.2017.3275
This genome-wide association study uses data from the Yale-Penn study to detect genetic risk variants for comorbid alcohol dependence and major depression and to determine whether polygenic risk alleles are shared with neuropsychiatric traits or subcortical brain volumes.
Jorim J. Tielbeek, MSc; Ada Johansson, PhD; Tinca J. C. Polderman, PhD; et al.
free access
JAMA Psychiatry. 2017;74(12):1242-1250. doi:10.1001/jamapsychiatry.2017.3069
This study estimates the single-nucleotide polymorphism鈥揵ased heritability of antisocial behavior; identifies novel genetic risk variants, genes, or biological pathways; tests for pleiotropic effects with other psychiatric traits; and reevaluates the candidate gene era data through the Broad Antisocial Behavior Consortium.
Gregory H. Cohen, MPhil, MSW; Shailesh Tamrakar, MS; Sarah Lowe, PhD; et al.
free access
JAMA Psychiatry. 2017;74(12):1251-1258. doi:10.1001/jamapsychiatry.2017.3037
This simulation study compares a stepped care case-finding intervention vs a moderate-strength single-level intervention on treatment effectiveness and cost-effectiveness in the 2 years after a natural disaster.
Antonio Terracciano, PhD; Yang An, MS; Angelina R. Sutin, PhD; et al.
free access
JAMA Psychiatry. 2017;74(12):1259-1265. doi:10.1001/jamapsychiatry.2017.2816
This cohort study examines whether changes in personality traits develop before the onset of mild cognitive impairment or dementia in individuals with no initial impairment.
Sanjeev Kumar, MD; Reza Zomorrodi, PhD; Zaid Ghazala, MD; et al.
free access
JAMA Psychiatry. 2017;74(12):1266-1274. doi:10.1001/jamapsychiatry.2017.3292
This cross-sectional study assesses the dorsolateral prefrontal cortex plasticity and its association with working memory in patients with early Alzheimer disease.