Eugenia Oviedo-Joekes, PhD; Daphne Guh, MSc; Suzanne Brissette, MD; et al.
free access
JAMA Psychiatry. 2016;73(5):447-455. doi:10.1001/jamapsychiatry.2016.0109
The SALOME randomized clinical trial tests if injectable hydromorphone is noninferior to injectable diacetylmorphine in reducing illicit heroin use after 6 months of intervention.
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Editorial
Meeting the Growing Need for Heroin Addiction Treatment
Richard S. Schottenfeld, MD; Stephanie S. O鈥橫alley, PhD
JAMA Psychiatry
Isidoor O. Bergfeld, MSc; Mariska Mantione, PhD; Mechteld L. C. Hoogendoorn, PhD; et al.
free access
JAMA Psychiatry. 2016;73(5):456-464. doi:10.1001/jamapsychiatry.2016.0152
This randomized clinical trial evaluates the effects of deep brain stimulation in patients with treatment-resistant depression and, in a crossover design, compares active and sham phases for possible detection of placebo effects.
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Editorial
Deep Brain Stimulation for Depression: Keeping an Eye on a Moving Target
Helen S. Mayberg, MD; Patricio Riva-Posse, MD; Andrea L. Crowell, MD
JAMA Psychiatry
Kenneth S. Kendler, MD; Henrik Ohlsson, PhD; Briana Mezuk, PhD; et al.
free access
JAMA Psychiatry. 2016;73(5):465-471. doi:10.1001/jamapsychiatry.2016.0053
This cohort study determines whether the developmental processes that predispose to schizophrenia are better reflected by the observed cognitive performance in adolescence or the deviation of that performance from an individual鈥檚 familial cognitive aptitude.
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Editorial
Predicting Schizophrenia
Richard S. E. Keefe, PhD; Abraham Reichenberg, PhD
JAMA Psychiatry
Richard Sherva, PhD; Qian Wang, MS; Henry Kranzler, MD; et al.
free access
has audio
JAMA Psychiatry. 2016;73(5):472-480. doi:10.1001/jamapsychiatry.2016.0036
This genome-wide association study assesses analyses from 3 studies of substance use disorder genetics to identify DSM-IV criteria for cannabis dependence in a large African American and European American cohort.
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Podcast:
Genome-wide Association Study of Cannabis Dependence (JAMA Psychiatry)
Daniel Kessler, BS; Michael Angstadt, MAS; Chandra Sripada, MD, PhD
free access
JAMA Psychiatry. 2016;73(5):481-489. doi:10.1001/jamapsychiatry.2016.0088
This study uses data from the Philadelphia Neurodevelopmental Cohort to evaluate the charting of brain intrinsic connectivity network patterns to serve as a measure of attention functioning in youth.
Jon E. Grant, JD, MD, MPH; Samuel R. Chamberlain, MD, PhD; Sarah A. Redden, BA; et al.
free access
JAMA Psychiatry. 2016;73(5):490-496. doi:10.1001/jamapsychiatry.2016.0060
This randomized clinical trial evaluates the use of N-acetylcysteine in short-term treatment of skin-picking disorder.
Divya Mehta, PhD; Felix C. Tropf, MSc; Jacob Gratten, PhD; et al.
free access
JAMA Psychiatry. 2016;73(5):497-505. doi:10.1001/jamapsychiatry.2016.0129
This investigation uses multiple independent genome-wide association study data sets to determine if there is a genetic association between schizophrenia and age at first birth using genetically informative but independently ascertained data sets.
Carolina Montano, BS; Margaret A. Taub, PhD; Andrew Jaffe, PhD; et al.
free access
JAMA Psychiatry. 2016;73(5):506-514. doi:10.1001/jamapsychiatry.2016.0144
This epigenome-wide association study examines differentially methylated positions across the genome in blood-derived DNA samples in a discovery and a replication set.
Theodore D. Satterthwaite, MD, MA; Daniel H. Wolf, MD, PhD; Monica E. Calkins, PhD; et al.
free access
JAMA Psychiatry. 2016;73(5):515-524. doi:10.1001/jamapsychiatry.2015.3463
Using a subsample of individuals from the Philadelphia Neurodevelopmental Cohort, this study investigates the presence of structural brain abnormalities in youth with psychosis spectrum symptoms.
Allison R. Kaup, PhD; Amy L. Byers, PhD, MPH; Cherie Falvey, MPH; et al.
free access
JAMA Psychiatry. 2016;73(5):525-531. doi:10.1001/jamapsychiatry.2016.0004
This prospective cohort study of black and white community-dwelling older adults in the Health, Aging, and Body Composition study investigates the association between trajectories of depressive symptoms and risk of dementia in older adults.