Sohei Kimoto, MD, PhD; Mark M. Zaki; H. Holly Bazmi, MS; et al.
free access
JAMA Psychiatry. 2015;72(8):747-756. doi:10.1001/jamapsychiatry.2015.0533
This study of brain tissue suggests that lower expression of NARP may lower the excitatory drive in schizophrenia.
Bridget F. Grant, PhD; Risë B. Goldstein, PhD, MPH; Tulshi D. Saha, PhD; et al.
free access
JAMA Psychiatry. 2015;72(8):757-766. doi:10.1001/jamapsychiatry.2015.0584
This national epidemiologic survey finds that alcohol use disorder is highly prevalent, highly comorbid, and disabling, with an urgent need for education of the public and policy makers, destigmatization of the disorder, and encouragement of those with the disorder to seek treatment.
Leonardo Cerliani, PhD; Maarten Mennes, PhD; Rajat M. Thomas, PhD; et al.
free access
JAMA Psychiatry. 2015;72(8):767-777. doi:10.1001/jamapsychiatry.2015.0101
This resting-state functional magnetic resonance imaging study compares the intrinsic functional connectivity between brain networks in a large sample of individuals with autism spectrum disorder and typically developing control subjects.
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Editorial
Resting-State Functional Connectivity in Psychiatric Disorders
Neil D. Woodward, PhD; Carissa J. Cascio, PhD
JAMA Psychiatry
Shulamite A. Green, PhD; Leanna Hernandez, MA; Nim Tottenham, PhD; et al.
free access
JAMA Psychiatry. 2015;72(8):778-786. doi:10.1001/jamapsychiatry.2015.0737
This fMRI study determines differences in brain responses, habituation, and connectivity during exposure to mildly aversive sensory stimuli in youth with autism spectrum disorders (ASDs) and sensory overresponsivity (SOR) compared with youth with ASDs without SOR and control subjects.
David Mataix-Cols, PhD; Kayoko Isomura, MD, PhD; Ana Pérez-Vigil, MD; et al.
free access
JAMA Psychiatry. 2015;72(8):787-793. doi:10.1001/jamapsychiatry.2015.0627
This population cohort, multigenerational, family study found that chronic tic disorders, including Tourette syndrome, cluster in families because of genetic disorders.
Andreas Frick, MSc; Fredrik Åhs, PhD; Jonas Engman, MSc; et al.
free access
JAMA Psychiatry. 2015;72(8):794-802. doi:10.1001/jamapsychiatry.2015.0125
This cross-sectional positron emission tomography study describes an overactive presynaptic serotonin system, with increased serotonin synthesis and transporter availability, in patients with social anxiety disorder.
Manabu Kubota, MD, PhD; Neeltje E. M. van Haren, PhD; Sander V. Haijma, MD; et al.
free access
JAMA Psychiatry. 2015;72(8):803-812. doi:10.1001/jamapsychiatry.2015.0712
This case-control study investigates the association between IQ and brain measures in patients with schizophrenia across time.
Yoji Hirano, MD, PhD; Naoya Oribe, MD, PhD; Shigenobu Kanba, MD, PhD; et al.
free access
JAMA Psychiatry. 2015;72(8):813-821. doi:10.1001/jamapsychiatry.2014.2642
This cross-sectional study reports an increase in spontaneous gamma activity during auditory steady-state stimulation in schizophrenia, reflecting a disruption in the normal balance of excitation and inhibition.
Kenneth L. Subotnik, PhD; Laurie R. Casaus, MD; Joseph Ventura, PhD; et al.
free access
JAMA Psychiatry. 2015;72(8):822-829. doi:10.1001/jamapsychiatry.2015.0270
This randomized clinical trial shows that long-acting injectable risperidone resulted in better clinical outcomes than oral risperidone.
Joris Berwaerts, MD; Yanning Liu, MS; Srihari Gopal, MD, MHS; et al.
free access
JAMA Psychiatry. 2015;72(8):830-839. doi:10.1001/jamapsychiatry.2015.0241
This placebo-controlled randomized clinical trial evaluates the safety and efficacy of the 3-month formulation of paliperidone palmitate in delaying time to relapse of schizophrenia symptoms.