Glenn T. Konopaske, MD; Nicholas Lange, DSc; Joseph T. Coyle, MD; et al.
free access
JAMA Psychiatry. 2014;71(12):1323-1331. doi:10.1001/jamapsychiatry.2014.1582
This study assesses dendritic spine loss in the dorsolateral prefrontal cortex in individuals with schizophrenia and individuals with bipolar disorder and suggests that the 2 disorders may share some common pathophysiological features.
Richard A. Bryant, PhD; Lucy Kenny, PhD; Amy Joscelyne, PhD; et al.
free access
JAMA Psychiatry. 2014;71(12):1332-1339. doi:10.1001/jamapsychiatry.2014.1600
This randomized clinical trial shows that cognitive behavior therapy that includes exposure therapy to treat prolonged grief disorder facilitates emotional responses that reduce symptoms.
Thomas Vanicek, MD; Marie Spies, MD; Christina Rami-Mark, MSc; et al.
free access
JAMA Psychiatry. 2014;71(12):1340-1349. doi:10.1001/jamapsychiatry.2014.1226
This prospective study does not identify any involvement of changes in brain norepinephrine transporter availability or distribution in the pathogenesis of attention-deficit/hyperactivity disorder.
Christoph U. Correll, MD; Delbert G. Robinson, MD; Nina R. Schooler, PhD; et al.
free access
JAMA Psychiatry. 2014;71(12):1350-1363. doi:10.1001/jamapsychiatry.2014.1314
This study assesses cardiometabolic risk in patients with first-episode schizophrenia spectrum disorders.
Martin Gevonden, MSc; Jan Booij, PhD, MD; Wim van den Brink, PhD, MD; et al.
free access
JAMA Psychiatry. 2014;71(12):1364-1372. doi:10.1001/jamapsychiatry.2014.1325
This study presents preliminary evidence of dopamine sensitization in a socially excluded group of people with hearing impairment.
Snehal M. Pinto Pereira, PhD; Marie-Claude Geoffroy, PhD; Christine Power, PhD
free access
JAMA Psychiatry. 2014;71(12):1373-1380. doi:10.1001/jamapsychiatry.2014.1240
This prospective cohort study suggests that activity may alleviate depressive symptoms in the general population, whereas depressive symptoms in early adulthood may be a barrier to physical activity.
Meta-analysis
Ole Köhler, MD; Michael E. Benros, PhD; Merete Nordentoft, PhD; et al.
free access
JAMA Psychiatry. 2014;71(12):1381-1391. doi:10.1001/jamapsychiatry.2014.1611
This meta-analysis supports a proof-of-concept concerning use of anti-inflammatory treatment in depression.
Lynn M. Almli, PhD; Richard Duncan, PhD; Hao Feng, MSPH; et al.
free access
JAMA Psychiatry. 2014;71(12):1392-1399. doi:10.1001/jamapsychiatry.2014.1339
This study concludes that the robust joint test be used in candidate-gene and genome-wide association studies of psychiatric outcomes that consider environmental interactions.
Kate M. Scott, PhD; Ali Obaid Al-Hamzawi, DM, FICMS; Laura H. Andrade, MD, PhD; et al.
free access
JAMA Psychiatry. 2014;71(12):1400-1408. doi:10.1001/jamapsychiatry.2014.1337
This cross-sectional study conducted in 18 countries reports significant inverse associations between subjective social status and numerous DSM-IV mental disorders.
Meta-analysis
Bret R. Rutherford, MD; Emily Pott, BA; Jane M. Tandler, BA; et al.
free access
JAMA Psychiatry. 2014;71(12):1409-1421. doi:10.1001/jamapsychiatry.2014.1319
This meta-analysis reports that the average treatment change associated with placebo treatment in antipsychotic trials increased since 1960, while the change associated with medication treatment decreased.