Hsien-Yuan Lane, MD, PhD; Ching-Hua Lin, MD, PhD; Michael F. Green, PhD; et al.
free access
JAMA Psychiatry. 2013;70(12):1267-1275. doi:10.1001/jamapsychiatry.2013.2159
Lane and coauthors examine the clinical and cognitive efficacy and safety of add-on treatment of sodium benzoate for schizophrenia.
Roman Kotov, PhD; Shirley H. Leong, PhD; Ramin Mojtabai, MD, PhD, MPH; et al.
free access
has audio
JAMA Psychiatry. 2013;70(12):1276-1286. doi:10.1001/jamapsychiatry.2013.2350
Kotov et al examine the associations between symptom course and long-term outcome to identify natural boundaries within psychotic disorders. Kendler provides an editorial.
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Podcast:
Boundaries of Schizoaffective Disorder: Revisiting Kraepelin
Catherine Winsper, PhD; Swaran P. Singh, MBBS, MD, DM, FRCPsych; Steven Marwaha, PhD; et al.
free access
JAMA Psychiatry. 2013;70(12):1287-1293. doi:10.1001/jamapsychiatry.2013.2445
Winsper and colleagues aimed to determine whether there are subgroups of psychotic individuals characterized by different developmental trajectories to violent behavior.
Nina V. Kraguljac, MD; David M. White, MPH, MPA; Meredith A. Reid, MS; et al.
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has audio
JAMA Psychiatry. 2013;70(12):1294-1302. doi:10.1001/jamapsychiatry.2013.2437
In a combined 3-T structural magnetic resonance imaging and single-voxel proton magnetic resonance spectroscopy study, Kraguljac and coauthors evaluate hippocampal volumetric measures and neurometabolite levels in unmedicated patients with schizophrenia and the correlations between these markers. See the editorial by 脰ng眉r.
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Podcast:
Increased Hippocampal Glutamate and Volumetric Deficits in Unmedicated Patients With Schizophrenia
Danai Dima, PhD; Jigar Jogia, PhD; David Collier, PhD; et al.
free access
JAMA Psychiatry. 2013;70(12):1303-1311. doi:10.1001/jamapsychiatry.2013.2099
Dima et al determine whether genetic risk for bipolar disorder associated with CACNA1C rs1006737 and ANK3 rs10994336 is mediated through changes in regional activation and interregional connectivity of the facial affect鈥損rocessing network.
Rebecca M. Pearson, PhD; Jonathan Evans, MD; Daphne Kounali, PhD; et al.
free access
JAMA Psychiatry. 2013;70(12):1312-1319. doi:10.1001/jamapsychiatry.2013.2163
Pearson et al investigate the hypothesis that there are independent associations between antenatal and postnatal depression with offspring depression and that the risk pathways are different.
Robert S. Wilson, PhD; Sukriti Nag, MD, PhD; Patricia A. Boyle, PhD; et al.
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JAMA Psychiatry. 2013;70(12):1320-1328. doi:10.1001/jamapsychiatry.2013.2224
To test the hypothesis that neurodegeneration and neuronal density in brainstem aminergic nuclei are related to late-life depression, Wilson et al performed a clinicopathological cohort study among 124 older persons without dementia who had annual evaluations (with self-report of depressive symptoms), died, and underwent a postmortem neuropathological examination.
Hazel McCarthy, MSc; Norbert Skokauskas, MD, PhD; Aisling Mulligan, MB; et al.
free access
JAMA Psychiatry. 2013;70(12):1329-1337. doi:10.1001/jamapsychiatry.2013.2174
McCarthy et al compare adults with a childhood diagnosis of attention-deficit/hyperactivity disorder (ADHD) and control subjects to determine the specific location of possible ADHD-related differences in resting-state functional connectivity.
Bankole A. Johnson, DSc, MD; Nassima Ait-Daoud, MD; Xin-Qun Wang, MS; et al.
free access
JAMA Psychiatry. 2013;70(12):1338-1346. doi:10.1001/jamapsychiatry.2013.2295
Johnson et al determine the efficacy of topiramate vs placebo as a treatment for cocaine dependence.
Stacey C. Sigmon, PhD; Kelly E. Dunn, PhD; Kathryn Saulsgiver, PhD; et al.
free access
JAMA Psychiatry. 2013;70(12):1347-1354. doi:10.1001/jamapsychiatry.2013.2216
Sigmon et al evaluate the relative efficacy of 1-, 2-, and 4-week buprenorphine tapering regimens and subsequent naltrexone therapy in outpatients with prescription opioid dependence.
Hefei Wen, BA; Janet R. Cummings, PhD; Jason M. Hockenberry, PhD; et al.
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JAMA Psychiatry. 2013;70(12):1355-1362. doi:10.1001/jamapsychiatry.2013.2169
Wen et al examine the effect of state-level substance use disorder (SUD) parity laws on state-aggregate SUD treatment rates and the effect of recent federal SUD parity legislation.
Ana S. Iltis, PhD; Sahana Misra, MD; Laura B. Dunn, MD; et al.
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JAMA Psychiatry. 2013;70(12):1363-1371. doi:10.1001/jamapsychiatry.2013.2105
Iltis et al provide mental health researchers with practical approaches to (1) identify and define various intrinsic research risks, (2) communicate these risks to others (eg, potential participants, regulatory bodies, and society), (3) manage these risks during the course of a study, and (4) justify the risks.