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August 1, 2012, Vol 69, No. 8, Pages 762-860

This Month in Archives of General Psychiatry

This Month in Archives of General Psychiatry

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Arch Gen Psychiatry. 2012;69(8):763. doi:10.1001/archgenpsychiatry.2011.1219
Art and Images in Psychiatry

William Blake's The Great Red Dragon and the Woman Clothed With the Sun

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Arch Gen Psychiatry. 2012;69(8):765. doi:10.1001/archgenpsychiatry.2012.107
Original Article

Association of Mental Disorders in Early Adulthood and Later Psychiatric Hospital Admissions and Mortality in a Cohort Study of More Than 1 Million Men

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Arch Gen Psychiatry. 2012;69(8):823-831. doi:10.1001/archgenpsychiatry.2011.2000

Gale and colleagues investigate whether the risks of death associated with mental disorders diagnosed in young men are similar to the risks associated with hospital admission for these disorders.

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Reduced Natural Oscillatory Frequency of Frontal Thalamocortical Circuits in Schizophrenia

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Arch Gen Psychiatry. 2012;69(8):766-774. doi:10.1001/archgenpsychiatry.2012.147

Ferrarelli et al assess the natural frequency of the posterior parietal, motor, premotor, and prefrontal cortices in patients with schizophrenia and healthy control subjects.

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Prenatal Antipsychotic Exposure and Neuromotor Performance During Infancy

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Arch Gen Psychiatry. 2012;69(8):787-794. doi:10.1001/archgenpsychiatry.2012.160

In a prospective controlled study, Johnson et al examined whether intrauterine antipsychotic exposure is associated with deficits in neuromotor performance and habituation in 6-month-old infants.

Randomized Trial of Behavior Therapy for Adults With Tourette Syndrome

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Arch Gen Psychiatry. 2012;69(8):795-803. doi:10.1001/archgenpsychiatry.2011.1528

Wilhelm et al discuss the efficacy of a comprehensive behavioral intervention for tics in adults with Tourette syndrome of at least moderate severity.

Interactive Effect of Apolipoprotein E Genotype and Age on Hippocampal Activation During Memory Processing in Healthy Adults

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Arch Gen Psychiatry. 2012;69(8):804-813. doi:10.1001/archgenpsychiatry.2011.1893

Nichols and coauthors evaluated the interaction between age and the variation in the effect of the apolipoprotein E (APOE) e4 allele on hippocampal function during episodic memory in adults of 2 age groups.

Neural Responses to Affective and Cognitive Theory of Mind in Children With Conduct Problems and Varying Levels of Callous-Unemotional Traits

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Arch Gen Psychiatry. 2012;69(8):814-822. doi:10.1001/archgenpsychiatry.2011.2070

Sebastian and colleagues studied 31 boys with conduct problems and 16 control subjects to broaden understanding of neural processing in conduct problems using an affective-processing task including an empathy component. The study’s goal was also to explore dimensional contributions of conduct problems symptoms and callous-unemotional traits to variance in affective neural responses.

Neural Mechanisms of Decision Making in Hoarding Disorder

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Arch Gen Psychiatry. 2012;69(8):832-841. doi:10.1001/archgenpsychiatry.2011.1980

The neural mechanisms of impaired decision-making in hoarding disorder in patients with well-defined primary HD compared with patients with obsessive-compulsive disorder and healthy control subjects is examined by Tolin and colleagues.

Effect of Brain Structure, Brain Function, and Brain Connectivity on Relapse in Alcohol-Dependent Patients

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Arch Gen Psychiatry. 2012;69(8):842-852. doi:10.1001/archgenpsychiatry.2011.2026

To determine whether results from structural and functional magnetic resonance imaging are associated with relapse in detoxified alcohol-dependent patients, Beck and coauthors performed a cue-reactivity functional magnetic resonance experiment with alcohol-associated and neutral stimuli.

Meta-analysis

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The Nature of Dopamine Dysfunction in Schizophrenia and What This Means for Treatment: Meta-analysis of Imaging Studies

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Arch Gen Psychiatry. 2012;69(8):776-786. doi:10.1001/archgenpsychiatry.2012.169

Howes and coauthors investigate the nature of the dopaminergic dysfunction in schizophrenia using meta-analysis of in vivo studies.

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

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Arch Gen Psychiatry. 2012;69(8):854-860. doi:10.1001/archgenpsychiatry.2012.124

Hartz and coauthors reviewed available genetic studies containing measures of cigarettes per day and the genotype of rs16969968 or its proxy to determine whether the association between rs16969968 and smoking is modified by age at onset of regular smoking.

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