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April 1, 2012, Vol 69, No. 4, Pages 336-434

This Month in Archives of General Psychiatry

This Month in Archives of General Psychiatry

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Arch Gen Psychiatry. 2012;69(4):336. doi:10.1001/archgenpsychiatry.2011.1199
Art and Images in Psychiatry

Diego Rivera's Man at the Crossroads

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Arch Gen Psychiatry. 2012;69(4):337-338. doi:10.1001/archgenpsychiatry.2012.102
Original Article

Reduced Dopamine Receptor Sensitivity as an Intermediate Phenotype in Alcohol Dependence and the Role of the COMT Val158Met and DRD2 Taq1A Genotypes

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Arch Gen Psychiatry. 2012;69(4):339-348. doi:10.1001/archgenpsychiatry.2011.1335

Schellekens and coauthors conducted a case-control pharmacogenetic challenge study to test central dopamine receptor sensitivity as an intermediate phenotype for alcohol dependence.

Overlapping and Segregating Structural Brain Abnormalities in Twins With Schizophrenia or Bipolar Disorder

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Arch Gen Psychiatry. 2012;69(4):349-359. doi:10.1001/archgenpsychiatry.2011.1615

Whether patients with schizophrenia and patients with bipolar disorder display overlapping abnormalities in brain volumes and cortical thickness and whether these are caused by shared genetic or environmental influences were investigated by Hulshoff Pol et al.

Dorsolateral Prefrontal Cortex Activation During Emotional Anticipation and Neuropsychological Performance in Posttraumatic Stress Disorder

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Arch Gen Psychiatry. 2012;69(4):360-371. doi:10.1001/archgenpsychiatry.2011.1539

Aupperle and coauthors conducted a case-control, cross-sectional study to determine whether posttraumatic stress disorder (PTSD) relates to greater disruption in prefrontal-subcortical networks during emotional anticipation.

Prevalence, Persistence, and Sociodemographic Correlates of DSM-IV Disorders in the National Comorbidity Survey Replication Adolescent Supplement

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Arch Gen Psychiatry. 2012;69(4):372-380. doi:10.1001/archgenpsychiatry.2011.160

Kessler et al present estimates of 12-month and 30-day prevalence, persistence (12-month prevalence among lifetime cases and 30-day prevalence among 12-month cases), and sociodemographic correlates of commonly occurring DSM-IV disorders among adolescents in the National Comorbidity Survey Replication Adolescent Supplement (NCS-A).

Severity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication Adolescent Supplement

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Arch Gen Psychiatry. 2012;69(4):381-389. doi:10.1001/archgenpsychiatry.2011.1603

Kessler et al present national data on the 12-month prevalence and sociodemographic correlates of serious emotional disturbances.

Use and Abuse of Alcohol and Illicit Drugs in US Adolescents: Results of the National Comorbidity Survey–Adolescent Supplement

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Arch Gen Psychiatry. 2012;69(4):390-398. doi:10.1001/archgenpsychiatry.2011.1503

Swendsen et al examine the prevalence, age at onset, and sociodemographic correlates of alcohol and illicit drug use and abuse among US adolescents.

Evidence for Chronically Altered Serotonin Function in the Cerebral Cortex of Female 3,4-Methylenedioxymethamphetamine Polydrug Users

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Arch Gen Psychiatry. 2012;69(4):399-409. doi:10.1001/archgenpsychiatry.2011.156

In a cross-sectional case-control study comparing serotonin2A receptor levels in abstinent female MDMA (3,4-methylenedioxymethamphetamine) polydrug users with those in women who did not use MDMA, Di Iorio and coauthors determine whether MDMA use is associated with chronic reductions in serotonin signaling in the cerebral cortex of women as reflected by increased serotonin2A receptor levels.

Association of Depression With Increased Risk of Dementia in Patients With Type 2 Diabetes: The Diabetes and Aging Study

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Arch Gen Psychiatry. 2012;69(4):410-417. doi:10.1001/archgenpsychiatry.2011.154

Katon et al determine whether comorbid depression in patients with type 2 diabetes increases the risk of development of dementia.

Sex Differences in Availability of β2*-Nicotinic Acetylcholine Receptors in Recently Abstinent Tobacco Smokers

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Arch Gen Psychiatry. 2012;69(4):418-427. doi:10.1001/archgenpsychiatry.2011.1465

The availability of nicotinic acetylcholine receptors containing the β2 subunit (β2*-nAChRs) in male and female smokers vs nonsmokers was studied by Cosgrove et al and the associations among nicotinic acetylcholine receptors containing the β2 subunit availability, tobacco smoking characteristics, and female sex steroid hormone levels was determined.

Psychiatric Disorders With Postpartum Onset: Possible Early Manifestations of Bipolar Affective Disorders

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Arch Gen Psychiatry. 2012;69(4):428-434. doi:10.1001/archgenpsychiatry.2011.157

Using a population-based cohort, Munk-Olsen et al study to what extent psychiatric disorders with postpartum onset are early manifestations of an underlying bipolar affective disorder.

Reviewers List

Reviewers Who Completed a Review During 2011

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Arch Gen Psychiatry. 2012;69(4):E1-E8. doi:10.1001/archgenpsychiatry.2012.112
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