AS MEMBERS of the National Bioethics Advisory Commission (NBAC), we are grateful to Oldham et al for their careful and thoughtful analysis and critique of the NBAC's most recent report.¹ Their analysis demonstrates a clear grasp of both what the NBAC recommended and what reasoning lay behind these recommendations. We are pleased that they agree that many—perhaps most—of the NBAC's recommendations identify valuable protections for potential research subjects. We offer a few observations and responses to their article.

First, Oldham et al² refer to the NBAC's division into "2 formal subcommittees, the Human Subjects Subcommittee and the Genetics Subcommittee." Although the Human Subjects Subcommittee did some preliminary work on the topic of this report, everything in the report and all the recommendations were considered by the commission as a whole. The report is the NBAC's product.