LET ME assure the reader who may have a response to a presumptious title that what follows does not comprise any final view or comprehensive statement; in this case at least, the appearance is not the reality. Rather, my discussion proceeds from a particular point of view (or bias, if you wish) 鈥攏amely, that of a psychopharmacologist over 30 years of age, who has learned from experience that subjective effects of drugs鈥� ie, changes in feelings and perceptions reported verbally by the subject鈥攄o not always correspond to the observable behavior manifested by the subject. When ther is a discrepancy, the subject's observable behavior is the better prognosticator of consequences for his health and for the health of others in his social milieu. Consider the drunkard, or, to stray from psychopharmacology proper, consider the manic or schizophrenic with delusions of grandeur. I am tempted, at this point, to even further