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Comment & Response
April 24, 2024

Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode

Author Affiliations
  • 1Augusta University, Augusta, Georgia
  • 2Medical University of South Carolina, Charleston
JAMA Psychiatry. 2024;81(7):736-737. doi:10.1001/jamapsychiatry.2024.0692

To the Editor Electroconvulsive therapy (ECT) is widely regarded as the most effective short-term treatment for major depressive episodes, including treatment-resistant depression (TRD). Deng et al1 recently reported in JAMA Psychiatry the Clinical Outcomes of Magnetic Seizure Therapy (MST) vs ECT for Major Depressive Episode study, finding that the efficacy of ECT and MST were 鈥渋ndistinguishable.鈥 Expanding the interventions considered effective in TRD is welcome, given the dire need. However, the ECT remission rate after short-term treatment was exceptionally low, limiting confidence in the validity and/or generalizability of the findings.

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