Keeping Up With Outcomes for Infants Born at Extremely Low Gestational Ages

Original Investigation

Survival and Morbidity of Preterm Children

Pierre-Yves聽Ancel,聽PhD; Fran莽ois聽Goffinet,聽PhD; and the EPIPAGE-2 Writing Group; Pierre聽Kuhn,聽PhD; Bruno聽Langer,聽MD; Jacqueline聽Matis,聽MD; Xavier聽Hernandorena,聽MD; Pierre聽Chabanier; Laurence聽Joly-Pedespan,聽MD; B茅n茅dicte聽Lecomte,聽MD; Fran莽oise聽Vendittelli,聽PhD; Michel聽Dreyfus,聽MD; Bernard聽Guillois,聽MD; Antoine聽Burguet,聽PhD; Pierre聽Sagot,聽MD; Jacques聽Sizun,聽MD; Alain聽Beuch茅e,聽MD; Florence聽Rouget,聽MD; Am茅lie聽Favreau,聽MD; Elie聽Saliba,聽PhD; Nathalie聽Bednarek,聽PhD; Patrice聽Morville,聽MD; G茅rard聽Thiriez,聽PhD; Lo茂c聽Marpeau,聽MD; St茅phane聽Marret,聽PhD; Gilles聽Kayem,聽PhD; Xavier聽Durrmeyer,聽MD; Mich猫le聽Granier,聽MD; Olivier聽Baud,聽PhD; Pierre-Henri聽Jarreau,聽PhD; Delphine聽Mitanchez,聽PhD; Pascal聽Boileau,聽PhD; Pierre聽Boulot,聽MD; Gilles聽Cambonie,聽PhD; Hubert聽Daud茅,聽MD; Antoine聽B茅du,聽PhD; Fabienne聽Mons,聽PhD; Jeanne聽Fresson,聽PhD; Rachel聽Vieux,聽PhD; Corine聽Alberge,聽MD; Catherine聽Arnaud,聽PhD; Christophe聽Vayssi猫re,聽MD; Patrick聽Truffert,聽PhD; V茅ronique聽Pierrat,聽PhD; Damien聽Subtil,聽PhD; Claude聽D鈥橢rcole,聽MD; Catherine聽Gire,聽MD; Umberto聽Simeoni,聽MD; Andr茅聽Bongain,聽PhD; Lo茂c聽Sentilhes,聽PhD; Jean-Christophe聽Roz茅,聽PhD; Jean聽Gondry,聽MD; Andr茅聽Leke,聽PhD; Michel聽Deiber,聽MD; Olivier聽Claris,聽PhD; Jean-Charles聽Picaud,聽PhD; Anne聽Ego,聽PhD; Thierry聽Debillon,聽PhD; Anne聽Poulichet,聽MD; Eliane聽Colin茅,聽MD; Anne聽Favre,聽MD; Olivier聽Fl茅chelles,聽MSc; Sylvain聽Samperiz,聽MD; Duksha聽Ramful,聽MD; Bernard聽Branger; Val茅rie聽Benhammou,聽PhD; Laurence聽Foix-L鈥橦茅lias,聽PhD; Laetitia聽Marchand-Martin,聽MSc; Monique聽Kaminski,聽MSc

JAMA Pediatrics
Comment & Response

Behavioral Epigenetics of Family-Centered Care in the Neonatal Intensive Care Unit

Livio聽Provenzi,聽PsyD; Serena聽Barello,聽PhD

JAMA Pediatrics

Neonatal intensive care has been one of the success stories of the past 30 years, with steadily improving survival and slowly improving long-term outcomes for infants born early. In the 1980s, few infants born at 25 through 26 weeks of gestation survived, but now high survival and low morbidity rates are expected throughout the developed world. The outcome for infants born at the decreasing limit of viability has continually evoked anxiety in terms of the balance between poor survival with high rates of neuroimpairment and the burden of providing intensive care for many weeks or months. In 1980, this limit was 25 through 26 weeks; now it is 23 weeks. This issue is frequently described as an ethical dilemma as to whether intensive care should be instituted for these children.¹

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