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JAMA Oncology Clinical Challenge
June 27, 2024

A Case of Gastric Thickening and a Large Ovarian Mass

Author Affiliations
  • 1Division of Hematology Oncology, Mayo Clinic, Phoenix, Arizona
  • 2Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, Arizona
JAMA Oncol. 2024;10(9):1282-1283. doi:10.1001/jamaoncol.2024.1816

A 35-year-old female patient with hypothyroidism and Ehler-Danlos syndrome presented with fatigue, abdominal distension, and dyspnea. She was in good health until 3 weeks prior when she noticed an enlarging nontender right axillary mass. During the previous 2 weeks, she also experienced increasing abdominal distension and indigestion that was worse after food intake. Two days before presentation, she developed dyspnea with exertion. The patient occasionally felt hot but denied fever, night sweats, or weight loss. Her review of systems was negative for chest pain, palpitations, recent sickness contact, or travel. She denied recreational substance use or occupational exposure to carcinogens. She had a relative with breast cancer.

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