Melinda C. Power, ScD; Erin E. Bennett, MPH; Robert W. Turner, PhD; et al.
free access
JAMA Neurol. 2021;78(3):275-284. doi:10.1001/jamaneurol.2020.4471
This cohort study uses data from the Health and Retirement Study to assess for changes in racial disparities in Alzheimer dementia prevalence and incidence among non-Hispanic Black and White individuals in the US from 2000 to 2016.
Elizabeth A. Thiele, MD, PhD; E. Martina Bebin, MD, MPA; Hari Bhathal, MD; et al.
open access
JAMA Neurol. 2021;78(3):285-292. doi:10.1001/jamaneurol.2020.4607
This double-blind, placebo-controlled, randomized clinical trial evaluates the safety of 2 dosages of cannabidiol for treatment of seizures in patients with tuberous sclerosis complex.
Reisa Sperling, MD; David Henley, MD; Paul S. Aisen, MD; et al.
free access
JAMA Neurol. 2021;78(3):293-301. doi:10.1001/jamaneurol.2020.4857
This randomized clinical trial evaluates the short-term effects of atabecestat in preclinical Alzheimer disease.
Roopa Rajan, MD, DM; Achal K. Srivastava, DM; Reghu Anandapadmanabhan, MTech; et al.
free access
has audio
JAMA Neurol. 2021;78(3):302-311. doi:10.1001/jamaneurol.2020.4766
This randomized clinical trial assesses the effect of botulinum neurotoxin injections on tremor in patients with upper-extremity dystonic tremor.
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Podcast:
Assessment of Botulinum Neurotoxin Injection for Dystonic Hand Tremor
Tanya Simuni, MD; Brian Fiske, PhD; Kalpana Merchant, PhD; et al.
open access
JAMA Neurol. 2021;78(3):312-320. doi:10.1001/jamaneurol.2020.4725
This randomized clinical trial assesses safety and tolerability of nilotinib in participants with moderately advanced Parkinson disease.
Pierre Seners, MD; Wagih Ben Hassen, MD; Bertrand Lapergue, MD; et al.
free access
JAMA Neurol. 2021;78(3):321-328. doi:10.1001/jamaneurol.2020.4557
This cohort study aims to develop and validate an easily applicable predictive score of early neurological deterioration of presumed ischemic origin following intravenous thrombolysis in patients with minor stroke and large vessel occlusion (LVO).
Linda D鈥橝ntona, MD, MBBS; Melida Andrea Jaime Merchan, MD; Anna Vassiliou, iBSc; et al.
open access
JAMA Neurol. 2021;78(3):329-337. doi:10.1001/jamaneurol.2020.4799
This systematic review and meta-analysis provides an objective summary of the available evidence on the clinical presentation, investigations findings, and treatment outcomes for spontaneous intracranial hypotension.
Sebastiaan M. Bossers, MD; Stephan A. Loer, PhD; Frank W. Bloemers, PhD; et al.
free access
JAMA Neurol. 2021;78(3):338-345. doi:10.1001/jamaneurol.2020.4596
This cohort study investigates the mortality and functional outcomes of individuals who received a prehospital dose of tranexamic acid for suspected severe traumatic brain injury.