PEDIATRICS
Rafaela Wagner, BS; Thalita Cecília Lima, BS; Marielen Ribeiro Tavares da Silva, BS; et al.
This nonrandomized controlled trial assesses the concordance between measurements from a telemedicine physical examination using a mobile medical device and measurements from a conventional in-person physical examination among pediatric patients.
JAMA Netw Open. 2023;6(2):e2252570. doi:10.1001/jamanetworkopen.2022.52570
ENVIRONMENTAL HEALTH
Xinye Qiu, PhD; Liuhua Shi, ScD; Laura D. Kubzansky, PhD; et al.
This cohort study investigates if long-term exposure to air pollution is associated with increased risk of late-life depression diagnosis among US older adults.
JAMA Netw Open. 2023;6(2):e2253668. doi:10.1001/jamanetworkopen.2022.53668
GERIATRICS
Melanie Chin, MD, MScHQ; Tetyana Kendzerska, MD, PhD; Jiro Inoue, PhD; et al.
This cross-sectional study examines the agreement between the Hospital Frailty Risk Score and the Clinical Frailty Scale among hospitalized individuals with chronic obstructive pulmonary disease (COPD) and examines the sensitivity and specificity of the scales to detect frailty.
JAMA Netw Open. 2023;6(2):e2253692. doi:10.1001/jamanetworkopen.2022.53692
PUBLIC HEALTH
Kyaw Zay Ya, MB, BS, MPH; Phyo Thet Naing Win, MB, BS, MPH; Julia Bielicki, PhD; et al.
This systematic review and meta-analysis synthesizes current evidence regarding the association between antimicrobial stewardship programs and the consumption of antibiotics globally.
JAMA Netw Open. 2023;6(2):e2253806. doi:10.1001/jamanetworkopen.2022.53806
OTOLARYNGOLOGY
Haojiang Li, MD; Di Cao, MD; Shuqi Li, MM; et al.
This cohort study investigates the prognostic value and biological associations of hepatitis B surface antigen and plasma Epstein-Barr virus DNA levels with distant metastasis in patients with nasopharyngeal carcinoma.
JAMA Netw Open. 2023;6(2):e2253832. doi:10.1001/jamanetworkopen.2022.53832
INFECTIOUS DISEASES
Winston E. Abara, MD; Julianne Gee, MPH; Paige Marquez, MSPH; et al.
This cohort study investigates the association of Ad26.COV2.S, BNT162b2, and mRNA-1273 COVID-19 vaccination with rates of Guillain-Barré syndrome among US adults.
JAMA Netw Open. 2023;6(2):e2253845. doi:10.1001/jamanetworkopen.2022.53845
HEALTH POLICY
Lindsay J. Peterson, PhD; John R. Bowblis, PhD
This quality improvement study assesses star ratings that are specific to recertification surveys and ratings specific to complaint investigations for the purpose of assessing potential differences between the 2 components.
JAMA Netw Open. 2023;6(2):e2253952. doi:10.1001/jamanetworkopen.2022.53952
OPHTHALMOLOGY
Xinxing Guo, MD, PhD; Michael V. Boland, MD, PhD; Bonnie K. Swenor, PhD, MPH; et al.
This quality improvement study evaluates low vision rehabilitation service use before and after implementation of an electronic health record–based clinical decision support system at a large ophthalmology department in an academic medical center.
JAMA Netw Open. 2023;6(2):e2254006. doi:10.1001/jamanetworkopen.2022.54006
NEPHROLOGY
Fan Fan Hou, MD, PhD; Di Xie, MD, PhD; Jun Wang, MD, PhD; et al.
This randomized clinical trial investigates the risk of kidney outcomes among patients with progressive IgA nephropathy receiving mycophenolate mofetil with supportive care vs supportive care alone.
JAMA Netw Open. 2023;6(2):e2254054. doi:10.1001/jamanetworkopen.2022.54054
PEDIATRICS
Mallory J. Owen, MB, ChB; Meredith S. Wright, PhD; Sergey Batalov, MS; et al.
This cohort study examines the association of genetic diseases with infant mortality at a large pediatric hospital system in San Diego County, California.
JAMA Netw Open. 2023;6(2):e2254069. doi:10.1001/jamanetworkopen.2022.54069
INFECTIOUS DISEASES
Anneli Uusküla, PhD; Marek Oja, PhD; Sirli Tamm, MS; et al.
This cross-sectional study examines the prevaccination prevalence of high-risk human papillomavirus (HPV) and type distribution by cervical cytology grade in Estonia.
JAMA Netw Open. 2023;6(2):e2254075. doi:10.1001/jamanetworkopen.2022.54075
PEDIATRICS
Andrew W. Manigault, PhD; Stephen J. Sheinkopf, PhD; Brian S. Carter, MD; et al.
This cohort study evaluates the association between acoustic cry characteristics in preterm infants and developmental and behavioral outcomes at 2 years of age.
JAMA Netw Open. 2023;6(2):e2254151. doi:10.1001/jamanetworkopen.2022.54151
PEDIATRICS
Jette J. Bakhuizen, MD; Saskia M. J. Hopman, MD, PhD; Machteld I. Bosscha, MD; et al.
This cohort study examines a Dutch national children’s cancer center’s experience in diagnosing cancer predisposition syndromes before introducing routine next-generation genetic sequencing.
JAMA Netw Open. 2023;6(2):e2254157. doi:10.1001/jamanetworkopen.2022.54157
GENETICS AND GENOMICS
Bill H. Diplas, MD, PhD; Ryan Ptashkin, MS; Joanne F. Chou, MPH; et al.
This cohort study assesses the association of clonal hematopoiesis with progression-free and overall survival among patients with metastatic colorectal and esophagogastric cancers who were undergoing treatment with first-line chemotherapy or immunotherapy.
JAMA Netw Open. 2023;6(2):e2254221. doi:10.1001/jamanetworkopen.2022.54221
PEDIATRICS
Lidia Engel, PhD; Ishani Majmudar, MSc; Cathrine Mihalopoulos, PhD; et al.
This cohort study compares the quality of life of transgender and gender-diverse children and adolescents in Australia with that of their age-matched peers.
JAMA Netw Open. 2023;6(2):e2254292. doi:10.1001/jamanetworkopen.2022.54292
PEDIATRICS
Matthew M. Engelhard, MD, PhD; Ricardo Henao, PhD; Samuel I. Berchuck, PhD; et al.
This diagnostic study evaluates the accuracy of early autism detection models based on electronic health record data collected before age 1 year.
JAMA Netw Open. 2023;6(2):e2254303. doi:10.1001/jamanetworkopen.2022.54303
DIABETES AND ENDOCRINOLOGY
Edouard G. Mills, MD, PhD; Natalie Ertl, MSci; Matthew B. Wall, PhD; et al.
This randomized clinical trial investigates the physiological, behavioral, neural, and hormonal effects of kisspeptin administration in men with hypoactive sexual desire disorder.
JAMA Netw Open. 2023;6(2):e2254313. doi:10.1001/jamanetworkopen.2022.54313
INFECTIOUS DISEASES
Kristina L. Bajema, MD, MSc; Mazhgan Rowneki, MPH; Kristin Berry, PhD; et al.
This cohort study examines factors associated with receipt of COVID-19 vaccination and rates of vaccination among US veterans.
JAMA Netw Open. 2023;6(2):e2254387. doi:10.1001/jamanetworkopen.2022.54387
MEDICAL JOURNALS AND PUBLISHING
Eva Buck; Alyson Haslam, PhD; Jordan Tuia, BA; et al.
This cross-sectional study reviews original oncology trials to assess whether the declared use of medical writers is associated with trial success and the use of a particular type of end point.
JAMA Netw Open. 2023;6(2):e2254405. doi:10.1001/jamanetworkopen.2022.54405
HEMATOLOGY
Macy L. Early, BA; Ahizechukwu C. Eke, MBChB; Alison Gemmill, PhD; et al.
This cross-sectional study compares rates and odds of severe maternal morbidity and other adverse pregnancy outcomes among Black pregnant individuals with sickle cell disease vs anemia.
JAMA Netw Open. 2023;6(2):e2254545. doi:10.1001/jamanetworkopen.2022.54545
HEMATOLOGY
Macy L. Early, BA; Ahizechukwu C. Eke, MBChB, PhD; Alison Gemmill, PhD; et al.
This cross-sectional study of deliveries in US hospitals examines pregnancy outcomes for people with sickle cell disease (SCD) and compares adverse outcomes with Black and Non-Black populations without SCD.
JAMA Netw Open. 2023;6(2):e2254552. doi:10.1001/jamanetworkopen.2022.54552
HEALTH POLICY
Laura G. Burke, MD, MPH; Ryan C. Burke, PhD, MPH; E. John Orav, PhD; et al.
This cohort study examines whether market-level academic medical center presence is associated with outcomes for Medicare patients treated at nonteaching hospitals within the same markets.
JAMA Netw Open. 2023;6(2):e2254559. doi:10.1001/jamanetworkopen.2022.54559
SUBSTANCE USE AND ADDICTION
Andrea E. Strahan, PhD, MPP; Shaina Desai, MPH; Kun Zhang, PhD; et al.
This cross-sectional study evaluates trends in out-of-pocket costs for and characteristics of pharmacy-dispensed buprenorphine medications for opioid use disorder treatment by type of payer from 2015 to 2020.
JAMA Netw Open. 2023;6(2):e2254590. doi:10.1001/jamanetworkopen.2022.54590
ONCOLOGY
Anjali Gupta, BS; Quan Chen, PhD; Lauren E. Wilson, PhD; et al.
This cohort study assesses health care affordability, availability, and accessibility along with race and ethnicity in association with receipt of guideline-adherent care for ovarian cancer.
JAMA Netw Open. 2023;6(2):e2254595. doi:10.1001/jamanetworkopen.2022.54595
SURGERY
Natsuki Eguchi, BS; Ekamol Tantisattamo, MD, MPH; Dean Chung, BS; et al.
This cohort study evaluates outcomes among undocumented immigrant kidney transplant recipients in California.
JAMA Netw Open. 2023;6(2):e2254660. doi:10.1001/jamanetworkopen.2022.54660
CARDIOLOGY
Carolyn M. Larsen, MD; Mariana Garcia Arango, MD; Harika Dasari, MBBS; et al.
This case-control study compares the long-term incidence of congestive heart failure in patients treated for breast cancer or lymphoma with anthracycline therapy compared with healthy controls from the same community.
JAMA Netw Open. 2023;6(2):e2254669. doi:10.1001/jamanetworkopen.2022.54669
PSYCHIATRY
C. Austin Zamarripa, PhD; Tory R. Spindle, PhD; Renuka Surujunarain; et al.
This randomized clinical trial compares the pharmacokinetics and pharmacodynamics of orally administered Δ9-tetrahydrocannabinol (THC)-dominant and cannabidiol-dominant cannabis extracts that contained the same Δ9-THC dose in a healthy adult population of US adults.
JAMA Netw Open. 2023;6(2):e2254752. doi:10.1001/jamanetworkopen.2022.54752
PUBLIC HEALTH
Rachel D’Amico, MD; Djhenne Dalmacy, MS; Jenifer A. Akinduro, MD, MS; et al.
This cohort study of US insurance claims data examines rates of appropriate postpartum primary care follow-up and diabetes-related care among patients who experienced gestational diabetes.
JAMA Netw Open. 2023;6(2):e2254765. doi:10.1001/jamanetworkopen.2022.54765
NEUROLOGY
Keun Hye Jeon, MD; Kyungdo Han, PhD; Su-Min Jeong, MD; et al.
This cohort study investigates the association of comprehensive patterns of changes in alcohol consumption with the incidence of all-cause dementia, Alzheimer disease, and vascular dementia among individuals in Korea.
JAMA Netw Open. 2023;6(2):e2254771. doi:10.1001/jamanetworkopen.2022.54771
PUBLIC HEALTH
Yuchen Wei, PhD; Katherine Min Jia, MSc; Shi Zhao, PhD; et al.
This case-control study examines change over time in estimated vaccine effectiveness against hospitalization and mortality caused by the SARS-CoV-2 Omicron variant among adults in Hong Kong.
JAMA Netw Open. 2023;6(2):e2254777. doi:10.1001/jamanetworkopen.2022.54777
PEDIATRICS
Danielle A. Rankin, PhD, MPH, CIC; Andrew J. Spieker, PhD; Ariana Perez, MPH; et al.
This cross-sectional study describes the detection of rhinoviruses and/or enteroviruses by pediatric age group and health care setting.
JAMA Netw Open. 2023;6(2):e2254909. doi:10.1001/jamanetworkopen.2022.54909
GLOBAL HEALTH
Sunil Rajpal, PhD; Akhil Kumar; Mira Johri, PhD; et al.
This cross-sectional study uses data from National Family Health Surveys to examine patterns among children aged 12 to 23 months who have not received a single dose of the diphtheria-tetanus-pertussis vaccine across all states and union territories in India from 1993 to 2021.
JAMA Netw Open. 2023;6(2):e2254919. doi:10.1001/jamanetworkopen.2022.54919
EQUITY, DIVERSITY, AND INCLUSION
Michelle Ko, MD, PhD; Mark C. Henderson, MD; Tonya L. Fancher, MD, MPH; et al.
This qualitative study uses key-informant interviews to describe US medical school admissions leaders’ experiences with barriers to and advances in diversity, equity, and inclusion in admissions policies and processes.
JAMA Netw Open. 2023;6(2):e2254928. doi:10.1001/jamanetworkopen.2022.54928
OBSTETRICS AND GYNECOLOGY
See Ling Loy, PhD; Chee Wai Ku, MD; Michelle Mei Ying Tiong, BMed; et al.
This cohort study assesses the association between lifestyle factors and probability of conception within a menstrual cycle among females of reproductive age in Singapore.
JAMA Netw Open. 2023;6(2):e2255001. doi:10.1001/jamanetworkopen.2022.55001
ONCOLOGY
Xue Hou, MD; Meichen Li, PhD; Guowu Wu, MSc; et al.
This randomized clinical trial compares the use of gefitinib plus chemotherapy with gefitinib monotherapy in patients with untreated EGFR-mutant non–small cell lung cancer brain metastases.
JAMA Netw Open. 2023;6(2):e2255050. doi:10.1001/jamanetworkopen.2022.55050
PUBLIC HEALTH
Muluemebet Kassa Mezen, MPH; Getasew Assefa Lemlem, MSc; Yemisrach Belete Biru, MPH; et al.
This cross-sectional study assesses the association of war with vaccination dropout among children younger than 2 years in the North Wollo zone of Ethiopia.
JAMA Netw Open. 2023;6(2):e2255098. doi:10.1001/jamanetworkopen.2022.55098
PHARMACY AND CLINICAL PHARMACOLOGY
Elizabeth M. Magnan, MD, PhD; Daniel J. Tancredi, PhD; Guibo Xing, PhD; et al.
This cohort study examines outcomes associated with tapering of opioid therapy in patients who have received stable doses for 1 year, including subcohorts of those with hypertension or diabetes.
JAMA Netw Open. 2023;6(2):e2255101. doi:10.1001/jamanetworkopen.2022.55101
EQUITY, DIVERSITY, AND INCLUSION
Alexander Waselewski, MD; Marika Waselewski, MPH; Eric Waselewski, MD; et al.
This qualitative study surveys adolescents and young adults in the US to assess their experiences and perspectives on the inclusion of transgender individuals in competitive sports.
JAMA Netw Open. 2023;6(2):e2255107. doi:10.1001/jamanetworkopen.2022.55107
EQUITY, DIVERSITY, AND INCLUSION
Dowin Boatright, MD, MBA, MHS; Maya London, BS; Arra Jane Soriano, MA; et al.
This qualitative study performs an exploratory content analysis to investigate what strategies and best practices are used by graduate medical education programs to improve diversity, equity, and inclusion in their programs with detailed narratives from residency program applicants.
JAMA Netw Open. 2023;6(2):e2255110. doi:10.1001/jamanetworkopen.2022.55110
HEALTH INFORMATICS
Yaping Zhang, MD, PhD; Mingqian Liu, MSc; Lu Zhang, MD; et al.
This diagnostic study evaluates chest radiography captions generated by natural language processing compared with the diagnostic findings of radiologists.
JAMA Netw Open. 2023;6(2):e2255113. doi:10.1001/jamanetworkopen.2022.55113
PEDIATRICS
Karen Pierce, PhD; Teresa H. Wen, PhD; Javad Zahiri, PhD; et al.
This diagnostic study investigates whether attention to high-affect motherese speech can be used as a diagnostic marker of autism spectrum disorder and language and social ability among toddlers aged 12 to 48 months.
JAMA Netw Open. 2023;6(2):e2255125. doi:10.1001/jamanetworkopen.2022.55125
GERIATRICS
Cyrus M. Kosar, PhD; Vincent Mor, PhD; Rachel M. Werner, MD, PhD; et al.
This cross-sectional study investigates whether hospitalized older adults with Alzheimer disease and related dementias are more likely to be discharged to lower-quality skilled nursing facilities following hospitalization.
JAMA Netw Open. 2023;6(2):e2255134. doi:10.1001/jamanetworkopen.2022.55134
ONCOLOGY
Niema B. Razavian, MD; Ralph B. D’Agostino Jr, PhD; Cole R. Steber, MD; et al.
This systematic review and meta-analysis assesses the risk of nodal failure within the contralateral nonirradiated neck after ipsilateral neck radiotherapy in patients with tonsil cancer.
JAMA Netw Open. 2023;6(2):e2255209. doi:10.1001/jamanetworkopen.2022.55209
HEALTH POLICY
Anam N. Ehsan, MBBS; Catherine A. Wu, MD; Alexandra Minasian, MS; et al.
This systematic review and meta-analysis examines the rate of financial toxicity among patients with breast cancer worldwide.
JAMA Netw Open. 2023;6(2):e2255388. doi:10.1001/jamanetworkopen.2022.55388
ONCOLOGY
Matthew J. Ehrhardt, MD, MS; Qi Liu, MS; Stephanie B. Dixon, MD, MS; et al.
This cohort study uses data from the St Jude Lifetime Cohort to assess the association of modifiable chronic health conditions and socioeconomic factors with late mortality among adult survivors of childhood cancer.
JAMA Netw Open. 2023;6(2):e2255395. doi:10.1001/jamanetworkopen.2022.55395
SURGERY
Kyung Mi Kim, PhD, RN; Karleen F. Giannitrapani, PhD; Ariadna Garcia, MS; et al.
This cross-sectional study evaluates the association between patient risk of hospitalization or death and goals-of-care conversations documented with a completed Life Sustaining Treatment Decisions Initiative note among individuals undergoing surgery in the Veterans Health Administration.
JAMA Netw Open. 2023;6(2):e2255407. doi:10.1001/jamanetworkopen.2022.55407
PEDIATRICS
Ryan Richard Ruff, PhD; Tamarinda Barry-Godín, DDS; Richard Niederman, DMD
This randomized clinical trial assessed the noninferiority of silver diamine fluoride with fluoride varnish vs traditional glass ionomer sealants with fluoride varnish after 2 years when provided to children via a school-based health care program.
JAMA Netw Open. 2023;6(2):e2255458. doi:10.1001/jamanetworkopen.2022.55458
PEDIATRICS
Jason M. Nagata, MD, MSc; Natalia Smith, BS; Sana Alsamman, BA; et al.
This cross-sectional study uses data from the Adolescent Brain Cognitive Development Study to assess the association of physical activity and screen time with overweight or obesity among adolescents in the US.
JAMA Netw Open. 2023;6(2):e2255466. doi:10.1001/jamanetworkopen.2022.55466
SUBSTANCE USE AND ADDICTION
Veronica R. Olaker, BS; Ellen K. Kendall, BA; Christina X. Wang, BA; et al.
This cohort study uses electronic health records of 2 821 182 US patients to examine associations of a new diagnosis of alcohol use disorder with COVID-19 over time from January 2020 through January 2022.
JAMA Netw Open. 2023;6(2):e2255496. doi:10.1001/jamanetworkopen.2022.55496
PUBLIC HEALTH
Christopher Doan, BS; Shuang Li, PhD; James S. Goodwin, MD
This cohort study examines the observed vs expected mammography and low-dose computed tomographic scan rates from the beginning of the COVID-19 pandemic through April 2022.
JAMA Netw Open. 2023;6(2):e2255589. doi:10.1001/jamanetworkopen.2022.55589
INFECTIOUS DISEASES
Lea Portmann, BSc; Marlieke E. A. de Kraker, PhD; Georg Fröhlich, MD; et al.
This cohort study compares in-hospital outcomes among patients hospitalized with the SARS-CoV-2 Omicron variant vs those hospitalized with influenza A or B in Switzerland.
JAMA Netw Open. 2023;6(2):e2255599. doi:10.1001/jamanetworkopen.2022.55599
DIABETES AND ENDOCRINOLOGY
Jinbo Hu, MD, PhD; Tingting Xu, MD; Hang Shen, MD; et al.
This diagnostic study investigates the accuracy of gallium-68 pentixafor positron emission tomography–computed tomography vs adrenal vein sampling in subtyping diagnosis of primary aldosteronism.
JAMA Netw Open. 2023;6(2):e2255609. doi:10.1001/jamanetworkopen.2022.55609
CARDIOLOGY
Kara K. Hoppe, DO, MS; Maureen Smith, MD, MPH, PhD; Jennifer Birstler, MS; et al.
This randomized clinical trial evaluates the effect of the My Hypertension Education And Reaching Target (MyHEART) intervention, a telephone coaching and blood pressure self-monitoring program, compared with usual care on changes in systolic and diastolic blood pressures and behaviors at 6 and 12 months among young adults with uncontrolled hypertension.
JAMA Netw Open. 2023;6(2):e2255618. doi:10.1001/jamanetworkopen.2022.55618
EQUITY, DIVERSITY, AND INCLUSION
Joseph Lunyera, MBChB, MSc; Clemontina A. Davenport, PhD; Patti Ephraim, MPH; et al.
This cross-sectional study examines hypertension self-management in Black individuals in socially disadvantaged settings.
JAMA Netw Open. 2023;6(2):e2255626. doi:10.1001/jamanetworkopen.2022.55626
PEDIATRICS
Mohammad Nazmus Sakib, MBBS, MSc, PhD; John R. Best, PhD; Peter A. Hall, PhD
This cohort study assesses bidirectional associations between adiposity and cognitive function in youth in the United States and tests mediational pathways through the lateral prefrontal cortext.
JAMA Netw Open. 2023;6(2):e2255631. doi:10.1001/jamanetworkopen.2022.55631
PEDIATRICS
Lindsey Rose Bullinger, PhD; Angela Boy, DrPH
This cross-sectional study evaluates the association between the 2021 expanded child tax credit payments and child abuse and neglect emergency department (ED) visits.
JAMA Netw Open. 2023;6(2):e2255639. doi:10.1001/jamanetworkopen.2022.55639
GERIATRICS
Kristian F. Axelsson, MD, PhD; Henrik Litsne; Mattias Lorentzon, MD, PhD
This nationwide cohort study investigates whether immobilized patients who use wheelchairs have a different risk of fracture and injurious falls compared with a matched control group of ambulatory adults in Sweden.
JAMA Netw Open. 2023;6(2):e2255645. doi:10.1001/jamanetworkopen.2022.55645
OBSTETRICS AND GYNECOLOGY
Eduard Mension, MD, MSc; Inmaculada Alonso, MD, PhD; Sònia Anglès-Acedo, MD, PhD; et al.
This randomized clinical trial assesses the safety and efficacy of carbon dioxide (CO2) vs sham vaginal laser treatment after 6 months of follow-up in survivors of breast cancer receiving aromatase inhibitors with genitourinary syndrome of menopause.
JAMA Netw Open. 2023;6(2):e2255697. doi:10.1001/jamanetworkopen.2022.55697
CARDIOLOGY
Shenghua Zhou, MD; Yichao Xiao, MD; Chonglun Zhou, MD; et al.
This randomized equivalence and noninferiority trial compares safety and efficacy of enoxaparin vs rivaroxaban 2.5 or 5 mg for patients with acute coronary syndrome (ACS) in the acute phase.
JAMA Netw Open. 2023;6(2):e2255709. doi:10.1001/jamanetworkopen.2022.55709
INFECTIOUS DISEASES
Matthew D. Sims, MD, PhD; Sahil Khanna, MBBS, MS; Paul Feuerstadt, MD; et al.
This phase 3, open-label, single-arm trial assesses the safety of SER-109 and the rate of recurrent Clostridioides difficile infection after administration of SER-109 following symptom resolution after antibiotic treatment among adults.
JAMA Netw Open. 2023;6(2):e2255758. doi:10.1001/jamanetworkopen.2022.55758
PEDIATRICS
James P. Marcin, MD, MPH; Hadley S. Sauers-Ford, MPH; Jamie L. Mouzoon, MA, MS, AMFT; et al.
This cluster randomized trial examines the use of telemedicine by pediatric referral centers to reduce the frequency of interfacility transfers among acutely ill children presenting to rural and community emergency departments.
JAMA Netw Open. 2023;6(2):e2255770. doi:10.1001/jamanetworkopen.2022.55770
INFECTIOUS DISEASES
Snežana Medić, MD, PhD; Cleo Anastassopoulou, PhD; Zagorka Lozanov-Crvenković, PhD; et al.
This cohort study of children and adolescents in Vojvodina, Serbia, assesses the reinfection risk of SARS-CoV-2.
JAMA Netw Open. 2023;6(2):e2255779. doi:10.1001/jamanetworkopen.2022.55779
ORTHOPEDICS
Mayank Jayaram, BS; Hao Wu, BE; Alfred P. Yoon, MD; et al.
This secondary analysis of the Wrist and Radius Injury Surgical Trial examines differences in outcomes after distal radius fracture managed with casting vs surgery in patients stratified by physiologic vs chronologic age.
JAMA Netw Open. 2023;6(2):e2255786. doi:10.1001/jamanetworkopen.2022.55786
CRITICAL CARE MEDICINE
Andrew J. Admon, MD, MPH, MS; Theodore J. Iwashyna, MD, PhD; Lee A. Kamphuis, MPH; et al.
This cohort study evaluates long-term physical and financial outcomes of individuals who were hospitalized with COVID-19.
JAMA Netw Open. 2023;6(2):e2255795. doi:10.1001/jamanetworkopen.2022.55795
OPHTHALMOLOGY
Zhenyu Zhong, MD; Qiuying Wu, MD; Yuxian Lai, MD; et al.
This randomized clinical trial compares recommendations for early and deferred non–messenger RNA COVID-19 vaccination with respect to ocular outcomes among patients with inactive uveitis.
JAMA Netw Open. 2023;6(2):e2255804. doi:10.1001/jamanetworkopen.2022.55804
PUBLIC HEALTH
Jason M. Devgun, MD; Rongmei Zhang, PhD; Jeffrey Brent, MD, PhD; et al.
This cohort study examines the incidence of bradycardia occurring during or after administration of remdesivir in patients with COVID-19 through the US Food and Drug Administration American College of Medical Toxicology COVID-19 Toxic (FACT) Pharmacovigilance Project.
JAMA Netw Open. 2023;6(2):e2255815. doi:10.1001/jamanetworkopen.2022.55815
EQUITY, DIVERSITY, AND INCLUSION
Chinenye M. Okafor, MD, MPH; Cenjing Zhu, MPhil; Valeria Raparelli, MD, PhD; et al.
This cohort study of patients with acute myocardial infarction (AMI) assesses whether race and social determinants of health are associated with hospital readmission rates within 1 year of discharge.
JAMA Netw Open. 2023;6(2):e2255843. doi:10.1001/jamanetworkopen.2022.55843
GERIATRICS
Tony Rosen, MD, MPH; Hao Zhang, PhD; Katherine Wen, PhD; et al.
This case-control study uses Medicare claims data to examine emergency department and hospital utilization among older adults experiencing elder mistreatment during the period surrounding initial mistreatment identification compared with that of other older adults.
JAMA Netw Open. 2023;6(2):e2255853. doi:10.1001/jamanetworkopen.2022.55853
INFECTIOUS DISEASES
Jessica Briggs, MD; Saki Takahashi, PhD; Patience Nayebare, MSc; et al.
This cohort study estimates SARS-CoV-2 seroprevalence, attack rates, and reinfection in rural eastern Uganda using serologic surveillance from 2020 to early 2022.
JAMA Netw Open. 2023;6(2):e2255978. doi:10.1001/jamanetworkopen.2022.55978
PEDIATRICS
David A. Brent, MD; Lisa M. Horowitz, PhD, MPH; Jacqueline Grupp-Phelan, MD, MPH; et al.
This cohort study compares the Ask Suicide-Screening Questions instrument with the Computerized Adaptive Screen for Suicidal Youth instrument for the prediction of suicidal behavior among adolescents seen in emergency departments (EDs), across demographic and clinical strata.
JAMA Netw Open. 2023;6(2):e2255986. doi:10.1001/jamanetworkopen.2022.55986
SURGERY
Callie Hlavin, MD; Phoebe Ingraham, MS; Tamara Byrd, MD; et al.
This cohort study conducted at a US academic hospital compares clinical outcomes and follow-up hospitalization of patients receiving bariatric surgery utilizing telemedicine for preoperative care with an in-person control group.
JAMA Netw Open. 2023;6(2):e2255994. doi:10.1001/jamanetworkopen.2022.55994
HEALTH POLICY
Caitlin B. Finn, MD; Chris Wirtalla, MBMI; Sanford E. Roberts, MD; et al.
This economic evaluation assesses the association of hospital referral choices with mortality risk, and the cost of these choices, in adults who underwent colorectal resection.
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JAMA Netw Open. 2023;6(2):e2255999. doi:10.1001/jamanetworkopen.2022.55999
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Podcast:
Simulated Outcomes of Colorectal Cancer Surgery at Highest-Performing vs Chosen Hospitals
SURGERY
Do Joong Park, MD, PhD; Sang-Uk Han, MD, PhD; Woo Jin Hyung, MD, PhD; et al.
This randomized clinical trial assesses whether laparoscopic proximal gastrectomy with double-tract reconstruction is superior to laparoscopic total gastrectomy for the surgical treatment of patients with early gastric cancer in the upper third of the stomach.
JAMA Netw Open. 2023;6(2):e2256004. doi:10.1001/jamanetworkopen.2022.56004
HEALTH POLICY
Anusha Naik, BS; Solomiya Syvyk, BA; Jason Tong, MD; et al.
This qualitative study describes the factors primary care physicians report considering when deciding whether to offer patients prescription medication vs a surgical referral.
JAMA Netw Open. 2023;6(2):e2256086. doi:10.1001/jamanetworkopen.2022.56086
PUBLIC HEALTH
Roy H. Perlis, MD, MSc; Kristin Lunz Trujillo, PhD; Alauna Safarpour, PhD; et al.
This survey study evaluates the association of post–COVID-19 condition symptoms with employment status.
JAMA Netw Open. 2023;6(2):e2256152. doi:10.1001/jamanetworkopen.2022.56152
PEDIATRICS
Monique M. Hedderson, PhD; Traci A. Bekelman, PhD, MPH; Mingyi Li, MHS; et al.
This cohort study evaluates changes in children’s screen time from before the pandemic to during the pandemic, from July 2019 through August 2021.
JAMA Netw Open. 2023;6(2):e2256157. doi:10.1001/jamanetworkopen.2022.56157
HEALTH POLICY
Marianne Luyendijk, MSc; Hedwig Blommestein, PhD; Carin Uyl-de Groot, PhD; et al.
This cohort study examines the postapproval processes and timing for making palbociclib, ribociclib, and abemaciclib available to patients with metastatic breast cancer in a high-income country.
JAMA Netw Open. 2023;6(2):e2256170. doi:10.1001/jamanetworkopen.2022.56170
PEDIATRICS
Francesca Sperotto, MD, PhD; Marco Daverio, MD, PhD; Angela Amigoni, MD; et al.
This systematic review and meta-analysis investigates incidence, trends, and factors associated with in-hospital cardiac arrest (IHCA) and mortality in children with cardiac disease in the intensive care unit (ICU).
JAMA Netw Open. 2023;6(2):e2256178. doi:10.1001/jamanetworkopen.2022.56178
NUTRITION, OBESITY, AND EXERCISE
Eleanor L. Watts, DPhil; Pedro F. Saint-Maurice, PhD; Aiden Doherty, PhD; et al.
This cohort study uses accelerometer data from UK Biobank participants to examine the association between physical activity and the risks of hospitalization for 25 common conditions and to estimate the proportion of hospitalizations that may be preventable with higher activity levels.
JAMA Netw Open. 2023;6(2):e2256186. doi:10.1001/jamanetworkopen.2022.56186
MEDICAL EDUCATION
Ann Poncelet, MD; Sally Collins, MA, MSc; Darren Fiore, MD; et al.
This qualitative study explores the value factors that health professional leaders placed on educator investment programs, including intramural grants and endowed chairs, through interviews at an urban academic health professions institute in the US.
JAMA Netw Open. 2023;6(2):e2256193. doi:10.1001/jamanetworkopen.2022.56193
OBSTETRICS AND GYNECOLOGY
Jennifer A. Jairam, MSc; Simone N. Vigod, MD, MSc; Arjumand Siddiqi, ScD; et al.
This population-based cohort study compares the risk of severe maternal morbidity or mortality between immigrant and nonimmigrant women residing exclusively within low-income neighborhoods in Ontario, Canada.
JAMA Netw Open. 2023;6(2):e2256203. doi:10.1001/jamanetworkopen.2022.56203
PUBLIC HEALTH
Odette Wegwarth, PhD; Ulrich Mansmann, PhD; Fred Zepp, MD; et al.
This cross-sectional study evaluates the vaccination intentions of COVID-19 vaccine hesitant adults during the Omicron wave in Germany following receipt of vaccine information through interactive simulation vs text.
JAMA Netw Open. 2023;6(2):e2256208. doi:10.1001/jamanetworkopen.2022.56208
PEDIATRICS
Cho Lee Wong, RN, PhD; Kai Chow Choi, PhD
This randomized clinical trial examines the effects of immersive virtual reality on reducing the pain, anxiety, and stress experienced by pediatric patients undergoing venipuncture.
JAMA Netw Open. 2023;6(2):e230001. doi:10.1001/jamanetworkopen.2023.0001
ONCOLOGY
Chiara A. Cella, MD, PhD; Maren Knoedler, MD; Marcia Hall, MD; et al.
This prognostic study assesses the ONKOTEV score as a novel risk assessment model to evaluate the risk of venous thromboembolism (VTE) among outpatients with cancer.
JAMA Netw Open. 2023;6(2):e230010. doi:10.1001/jamanetworkopen.2023.0010
ONCOLOGY
David J. Fei-Zhang, BA; Daniel C. Chelius, MD; Urjeet A. Patel, MD; et al.
This cohort study evaluates the association of overall social vulnerability and specific social determinants of health with disparities in head and neck cancer care and prognosis among children and adolescents in the United States.
JAMA Netw Open. 2023;6(2):e230016. doi:10.1001/jamanetworkopen.2023.0016
PEDIATRICS
Mingyao Sun; Honghao Lai; Feiyang Na, MD; et al.
This systematic review and network meta-analysis compares the efficacy and safety of 4 monoclonal antibodies for preventing respiratory syncytial virus among infants and children.
JAMA Netw Open. 2023;6(2):e230023. doi:10.1001/jamanetworkopen.2023.0023
CARDIOLOGY
Bilal Rayes, BSc; Maddalena Ardissino, MBBS; Eric A. W. Slob, PhD; et al.
This genetic association study uses mendelian randomization to examine factors associated with long-term outcomes of hypertensive disorders in pregnancy.
JAMA Netw Open. 2023;6(2):e230034. doi:10.1001/jamanetworkopen.2023.0034
GLOBAL HEALTH
Lucrezia Rovati, MD; Simon Zec, MD; Dmytro Dziuba, MD; et al.
This quality improvement study describes the development and implementation of a multimodal trauma critical care knowledge-exchange platform during the ongoing conflict in Ukraine and evaluates the reach of this intervention, together with participant engagement and satisfaction.
JAMA Netw Open. 2023;6(2):e230050. doi:10.1001/jamanetworkopen.2023.0050
GERIATRICS
Yichi Zhang, MS; James M. Wilkins, MD; Lily Gui Bessette, MS; et al.
This cohort study assesses antipsychotic medication use among older US adults, including rates of and patient characteristics associated with discontinuation, following infection-related hospitalization.
JAMA Netw Open. 2023;6(2):e230063. doi:10.1001/jamanetworkopen.2023.0063
PUBLIC HEALTH
Flávia Jôse O. Alves, PhD; Dandara Ramos, PhD; Enny S. Paixão, PhD; et al.
This cohort study uses national Brazilian linked data from health and social administrative databases to investigate the association between the Bolsa FamÃlia conditional cash transfer program and maternal mortality among women and girls of child-bearing age.
JAMA Netw Open. 2023;6(2):e230070. doi:10.1001/jamanetworkopen.2023.0070
DIABETES AND ENDOCRINOLOGY
Klemen Dovc, MD; Stefanie Lanzinger, PhD; Roque Cardona-Hernandez, MD; et al.
This cohort study evaluates the the association of different treatment modalities with achieving recommended glucose levels in a large, diverse, international cohort of children, adolescents, and young adults with type 1 diabetes.
JAMA Netw Open. 2023;6(2):e230077. doi:10.1001/jamanetworkopen.2023.0077
ONCOLOGY
Alexander Rühle, MD; Sebastian Marschner, MD; Marlen Haderlein, MD; et al.
This cohort study examines the outcomes of adding chemotherapy or cetuximab to radiotherapy treatment in older adults with locoregionally advanced head and neck squamous cell carcinoma.
JAMA Netw Open. 2023;6(2):e230090. doi:10.1001/jamanetworkopen.2023.0090
ONCOLOGY
Peng Yuan, MD; Yikun Kang, MD; Fei Ma, MD; et al.
This randomized clinical trial compares the long-term efficacy and toxic effects of epirubicin plus paclitaxel and the standard epirubicin and cyclophosphamide followed by paclitaxel regimen among women with ERBB2-negative, lymph node–positive breast cancer.
JAMA Netw Open. 2023;6(2):e230122. doi:10.1001/jamanetworkopen.2023.0122
PEDIATRICS
Jian-Rong He, DPhil; Yongfu Yu, PhD; Fang Fang, PhD; et al.
This cohort study used national registry data for all children born in Denmark between 1978 to 2015 to examine the association of maternal infection during pregnancy with childhood leukemia among offspring.
JAMA Netw Open. 2023;6(2):e230133. doi:10.1001/jamanetworkopen.2023.0133
HEALTH POLICY
Stanley Kalata, MD, MS; Ryan Howard, MD, MSc; Adrian Diaz, MD, MPH; et al.
This cross-sectional study assesses differences in surgical outcomes and spending for Medicare beneficiaries undergoing elective hip replacement procedures in hospital networks that have vertical integration of skilled nursing facilities vs those that do not.
JAMA Netw Open. 2023;6(2):e230140. doi:10.1001/jamanetworkopen.2023.0140
PSYCHIATRY
M. Ishrat Husain, MBBS, MD; Imran B. Chaudhry, MD; Ameer B. Khoso, MPhil; et al.
This randomized clinical trial of adults with treatment-resistant depression assesses whether adjunctive simvastatin therapy improves depressive symptoms compared with placebo.
JAMA Netw Open. 2023;6(2):e230147. doi:10.1001/jamanetworkopen.2023.0147
PEDIATRICS
Dardo Tomasi, PhD; Nora D. Volkow, MD
This cross-sectional study of US children aged 9 to 11 years assesses functional connectivity hubs displaying prominent sex differences and the association between global functional connectivity density and total cognitive scores.
JAMA Netw Open. 2023;6(2):e230157. doi:10.1001/jamanetworkopen.2023.0157
ONCOLOGY
Brian L. Sprague, PhD; Shuai Chen, PhD; Diana L. Miglioretti, PhD; et al.
This cohort study of US women aged 40 to 74 years undergoing mammography screening uses a risk prediction model to determine the cumulative 6-year risk of screen-detected ductal carcinoma in situ.
JAMA Netw Open. 2023;6(2):e230166. doi:10.1001/jamanetworkopen.2023.0166
OBSTETRICS AND GYNECOLOGY
Lyndsay A. Avalos, PhD, MPH; G. Thomas Ray, MBA; Stacey E. Alexeeff, PhD; et al.
This cross-sectional study compares the rates of unstable and/or unsafe living situations and intimate partner violence in individuals who were pregnant before vs during the COVID-19 pandemic.
JAMA Netw Open. 2023;6(2):e230172. doi:10.1001/jamanetworkopen.2023.0172
ONCOLOGY
Sung Jun Ma, MD; Jasmin Gill; Olivia Waldman, BSc; et al.
This cohort study of US women with estrogen receptor (ER)-positive breast cancer examines the association of income levels with 21-gene recurrence scores and survival outcomes.
JAMA Netw Open. 2023;6(2):e230179. doi:10.1001/jamanetworkopen.2023.0179
STATISTICS AND RESEARCH METHODS
Lue Ping Zhao, PhD; Seth Cohen, MD; Michael Zhao, BS; et al.
This cross-sectional study investigates the use of haplotype-based artificial intelligence to identify novel SARS-COV-2 variants and mutations.
JAMA Netw Open. 2023;6(2):e230191. doi:10.1001/jamanetworkopen.2023.0191
ENVIRONMENTAL HEALTH
Anaïs Teyton, MPH; Rebecca J. Baer, MPH; Tarik Benmarhnia, PhD; et al.
This cohort study examines the association of air pollution exposure and emergency department visits in the first year of life in full-term and preterm infants in California.
JAMA Netw Open. 2023;6(2):e230262. doi:10.1001/jamanetworkopen.2023.0262
COMPLEMENTARY AND ALTERNATIVE MEDICINE
Weiming Wang, MD, PhD; Yan Liu, MD; Xiaofang Yang, MD, PhD; et al.
This randomized clinical trial assesses the effect of electroacupuncture for opioid-induced constipation in patients with cancer in China.
JAMA Netw Open. 2023;6(2):e230310. doi:10.1001/jamanetworkopen.2023.0310
CRITICAL CARE MEDICINE
Shawniqua Williams Roberson, MEng, MD; Samuel Nwosu, MS; Erin M. Collar, MPH; et al.
This secondary analysis of a randomized clinical trial reports on the cognitive performance, risk of posttraumatic stress disorder and depression, and functional status 6 months after the administration of a treatment regimen consisting of antioxidants and hydrocortisone infusion in adults with sepsis.
JAMA Netw Open. 2023;6(2):e230380. doi:10.1001/jamanetworkopen.2023.0380
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Invited Commentary
Critical Care and the Postintensive Care Syndrome
Micah T. Long, MD; Robert D. Sanders, MD, PhD; Jean-Charles Preiser, MD, PhD
JAMA Netw Open
ONCOLOGY
Siran M. Koroukian, PhD; Sara L. Douglas, PhD, RN; Long Vu, MS; et al.
This cohort study uses data from the Surveillance, Epidemiology, and End Results database to compare markers of aggressive end-of-life care between older adults with metastatic cancer who are nursing home residents and their community-dwelling counterparts.
JAMA Netw Open. 2023;6(2):e230394. doi:10.1001/jamanetworkopen.2023.0394
ONCOLOGY
Bahar Saberzadeh-Ardestani, MD, MPH, MHPE; Jeremy C. Jones, MD; Joleen M. Hubbard, MD; et al.
This cohort study assesses the clinicopathological features, outcomes, and adverse events of older patients with metastatic colorectal adenocarcinomas.
JAMA Netw Open. 2023;6(2):e230400. doi:10.1001/jamanetworkopen.2023.0400
STATISTICS AND RESEARCH METHODS
Daniel Lammers, MD; Joshua Richman, MD, PhD; John B. Holcomb, MD; et al.
This quality improvement study describes the outcomes of bayesian statistical approaches using data from the Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial.
JAMA Netw Open. 2023;6(2):e230421. doi:10.1001/jamanetworkopen.2023.0421
OBSTETRICS AND GYNECOLOGY
Ka Wang Cheung, MD; Mimi Tin-Yan Seto, MBBS; Weilan Wang, PhD; et al.
This cross-sectional study assesses causes and timing of maternal death in Hong Kong and identifies deaths and their causes that were missed by the vital statistics database.
JAMA Netw Open. 2023;6(2):e230429. doi:10.1001/jamanetworkopen.2023.0429
DIABETES AND ENDOCRINOLOGY
Mu-Chi Chung, MD; Peir-Haur Hung, MD; Po-Jen Hsiao, MD; et al.
This cohort study investigates the association of sodium-glucose transport protein 2 inhibitor (SGLT2i) use and the incidence of acute kidney injury (AKI) in patients with type 2 diabetes in Taiwan.
JAMA Netw Open. 2023;6(2):e230453. doi:10.1001/jamanetworkopen.2023.0453
INFECTIOUS DISEASES
Roel P. J. Willems, MD; Martijn C. Schut, PhD; Anna M. Kaiser, MSc; et al.
This case-control study assesses the association between the use of proton pump inhibitors and the risk of acquiring drug-resistant Enterobacterales and examines interactions with possible microbiome-altering agents among adult hospitalized patients.
JAMA Netw Open. 2023;6(2):e230470. doi:10.1001/jamanetworkopen.2023.0470
ONCOLOGY
Alyssa Y. Li, BA; Karolina Gaebe, BMath; Amna Zulfiqar, MSc; et al.
This meta-analysis evaluates overall survival, progression-free survival, and intracranial progression-free survival in patients with stable vs progressive intracranial metastatic disease secondary to any primary cancer.
JAMA Netw Open. 2023;6(2):e230475. doi:10.1001/jamanetworkopen.2023.0475
SURGERY
Madeline Y. Ryu, BS; Matthew J. Martin, MD; Alexander H. Jin, AB; et al.
This qualitative study examines moral injury and distress among US military surgeons deployed to Iraq and Afghanistan during periods of high casualty volumes through a mixed-methods approach.
JAMA Netw Open. 2023;6(2):e230484. doi:10.1001/jamanetworkopen.2023.0484
HEALTH POLICY
Daniel A. Goldstein, MD; Gary M. Ginsberg, DrPH; Dorit Hofnung-Gabbay, MSc; et al.
This economic evaluation estimates the health care costs associated with using extended-interval fixed dosing instead of standard-interval fixed dosing of immune checkpoint inhibitors in a simulated cohort of patients with urothelial cancer.
JAMA Netw Open. 2023;6(2):e230490. doi:10.1001/jamanetworkopen.2023.0490
HEALTH INFORMATICS
Nicholas Konz, BS; Mateusz Buda, MS; Hanxue Gu, BS; et al.
This diagnostic study describes a grand challenge for using artificial intelligence (AI) to detect cancer in digital breast tomosynthesis images.
JAMA Netw Open. 2023;6(2):e230524. doi:10.1001/jamanetworkopen.2023.0524
INFECTIOUS DISEASES
Van Vo, PhD; Richard L. Tillett, PhD; Katerina Papp, PhD; et al.
This cross-sectional study leverages spatial and temporal differences in wastewater whole-genome sequencing data to quantify relative SARS-CoV-2 contributions from visitors to southern Nevada.
JAMA Netw Open. 2023;6(2):e230550. doi:10.1001/jamanetworkopen.2023.0550
ENVIRONMENTAL HEALTH
Stacey E. Alexeeff, PhD; Kamala Deosaransingh, MPH; Stephen Van Den Eeden, PhD; et al.
This cohort study examines associations between long-term fine particulate air pollution and cardiovascular events using electronic health record and geocoded address data.
JAMA Netw Open. 2023;6(2):e230561. doi:10.1001/jamanetworkopen.2023.0561
ONCOLOGY
Elisé G. Kaboré, MD; Conor Macdonald, PhD; Ahmed Kaboré, PhD; et al.
This systematic review evaluates risk prediction models of cardiotoxicity for patients with breast cancer.
JAMA Netw Open. 2023;6(2):e230569. doi:10.1001/jamanetworkopen.2023.0569
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Invited Commentary
Predicting Risk of Cardiotoxic Effects in Breast Cancer: Are We There Yet?
Tauben Averbuch, MD; Mamas A. Mamas, MD, PhD; Harriette G. C. Van Spall, MD, MPH
JAMA Netw Open
INFECTIOUS DISEASES
Takeaki Imamura, PhD; Aika Watanabe, PhD; Yusuke Serizawa, MD; et al.
This case series describes the characteristics of COVID-19 transmission within different social settings in Tokyo, Japan, and evaluates which settings are associated with onward transmission.
JAMA Netw Open. 2023;6(2):e230589. doi:10.1001/jamanetworkopen.2023.0589
ONCOLOGY
Tim de Back, MD; Isabelle Nijskens, MD; Pascale Schafrat, MD; et al.
This systematic review and meta-analysis explores the survival benefit associated with systemic treatment in patients with small intestinal adenocarcinomas.
JAMA Netw Open. 2023;6(2):e230631. doi:10.1001/jamanetworkopen.2023.0631
ONCOLOGY
Lauren M. Hurwitz, PhD, MHS; Penelope M. Webb, DPhil; Susan J. Jordan, PhD; et al.
This case-control study pools and analyzes individual-level data from 8 Ovarian Cancer Association Consortium case-control studies to evaluate whether a polygenic score modifies the association of frequent aspirin use with ovarian cancer.
JAMA Netw Open. 2023;6(2):e230666. doi:10.1001/jamanetworkopen.2023.0666
GENETICS AND GENOMICS
Christine Ladd-Acosta, PhD; Elizabeth Vang, BHSc, BASc; Emily S. Barrett, PhD; et al.
This cohort study evaluates whether exposure to each of 3 pregnancy complications (gestational diabetes, gestational hypertension, and preeclampsia) is associated with accelerated or decelerated gestational biological age in children at birth.
JAMA Netw Open. 2023;6(2):e230672. doi:10.1001/jamanetworkopen.2023.0672
PEDIATRICS
Daisuke Hitaka, MD; Satoshi Fujiyama, MD, PhD; Yukiko Nishihama, PhD; et al.
This quality improvement study examines blood alcohol concentrations in premature infants and evaporated alcohol concentrations within neonatal incubators before and after implementation of a practice limiting exposure of the infants to alcohol disinfectants.
JAMA Netw Open. 2023;6(2):e230691. doi:10.1001/jamanetworkopen.2023.0691
ONCOLOGY
Daichi Fujimoto, MD, PhD; Takeshi Morimoto, MD, PhD, MPH; Motohiro Tamiya, MD; et al.
This cohort study compares the outcomes of patients with extensive-stage small cell lung cancer who were included in clinical trials with outcomes of patients who were ineligible for those trials.
JAMA Netw Open. 2023;6(2):e230698. doi:10.1001/jamanetworkopen.2023.0698
HEALTH POLICY
Chia-Te Liao, MD; Han Siong Toh, MD; Li Sun, PhD; et al.
This economic evaluation estimates the lifetime direct medical costs and quality-adjusted life-years of intensive and standard systolic blood pressure treatments among the older population with hypertension in China, the UK, and the US to examine their cost-effectiveness.
JAMA Netw Open. 2023;6(2):e230708. doi:10.1001/jamanetworkopen.2023.0708
OBSTETRICS AND GYNECOLOGY
Natasha L. Orr, PhD; Alice J. Huang, BSc; Yang Doris Liu, MS; et al.
This cohort study explores the association between Central Sensitization Inventory scores and persistent pain after endometriosis surgery.
JAMA Netw Open. 2023;6(2):e230780. doi:10.1001/jamanetworkopen.2023.0780
ONCOLOGY
Raymond U. Osarogiagbon, MBBS; Wei Liao, PhD; Nicholas R. Faris, MDiv; et al.
This cohort study compares the cumulative incidence of lung cancer in screening-age populations within a lung nodule monitoring program and a lung cancer screening program in the Mississippi Delta.
JAMA Netw Open. 2023;6(2):e230787. doi:10.1001/jamanetworkopen.2023.0787
SURGERY
George Molina, MD, MPH; Mengyuan Ruan, MS; Stuart R. Lipsitz, ScD; et al.
This cross-sectional study uses Surveillance, Epidemiology, and End Results Research Plus data to examine the association of US county-level variation in receipt of liver metastasectomy for colorectal liver metastasis with poverty rates in 2010.
JAMA Netw Open. 2023;6(2):e230797. doi:10.1001/jamanetworkopen.2023.0797
EQUITY, DIVERSITY, AND INCLUSION
Samantha J. Boch, PhD, RN; Aaron W. Murnan, PhD, LMFT; Jordan F. Pollard, MEd, MSW; et al.
This cross-sectional study compares the number of incarceration-related projects funded at the National Institutes of Health, US Department of Justice, and National Science Foundation compared with other social and behavioral risk–related projects.
JAMA Netw Open. 2023;6(2):e230803. doi:10.1001/jamanetworkopen.2023.0803
HEALTH POLICY
Kirsten L. Johansen, MD; Shuling Li, PhD; Jiannong Liu, PhD; et al.
This cohort study examines changes in the use of home dialysis among patients with kidney failure after implementation of the End-Stage Renal Disease Treatment Choices payment model.
JAMA Netw Open. 2023;6(2):e230806. doi:10.1001/jamanetworkopen.2023.0806
HEALTH INFORMATICS
John-Jose Nunez, MD, MSc; Bonnie Leung, MN-NP(F); Cheryl Ho, MD; et al.
This prognostic study develops and evaluates neural natural language processing models that predict the survival of patients with general cancer using their initial oncologist consultation.
JAMA Netw Open. 2023;6(2):e230813. doi:10.1001/jamanetworkopen.2023.0813
SURGERY
Nicolas Meurisse, MD; Markoen Mertens, MD; Steffen Fieuws, PhD; et al.
This randomized clinical trial investigates the effect of a combined drug approach targeting the preimplantation liver graft and recipient on the severity of ischemia-reperfusion injury during transplant.
JAMA Netw Open. 2023;6(2):e230819. doi:10.1001/jamanetworkopen.2023.0819
NUTRITION, OBESITY, AND EXERCISE
Kelley Pettee Gabriel, PhD; Byron C. Jaeger, PhD; Cora E. Lewis, MD, MSPH; et al.
This cohort study evaluates whether cardiovascular fitness during the early periods of life is associated with morbidity and mortality outcomes and whether the outcomes vary by sex and race.
JAMA Netw Open. 2023;6(2):e230842. doi:10.1001/jamanetworkopen.2023.0842
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Invited Commentary
Importance of Optimizing Cardiorespiratory Fitness in Early Adulthood and Through Midlife
Hermes Florez, MD, PhD, MPH; JacKetta R. Cobbs, PhD, MPH; Mathew J. Gregoski, PhD, MSc
JAMA Netw Open
UROLOGY
Ian M. McElree, MS; Ryan L. Steinberg, MD; Sarah L. Mott, MS; et al.
This cohort study compares outcomes of treatment with sequential intravesical gemcitabine and docetaxel vs bacillus Calmette-Guérin among patients with high-risk non–muscle-invasive bladder cancer.
JAMA Netw Open. 2023;6(2):e230849. doi:10.1001/jamanetworkopen.2023.0849
EQUITY, DIVERSITY, AND INCLUSION
Mytien Nguyen, MS; Sarwat I. Chaudhry, MD; Mayur M. Desai, PhD, MPH; et al.
This cross-sectional study of National Institutes of Health (NIH) grants examines trends in gender, racial, and ethnic diversity among principal investigators, with a particular focus on investigators holding 3 or more research project grants.
JAMA Netw Open. 2023;6(2):e230855. doi:10.1001/jamanetworkopen.2023.0855
CARDIOLOGY
Julie C. Lauffenburger, PharmD, PhD; Renee A. Barlev, MD, MPH; Rasha Khatib, PhD; et al.
This qualitative study of 15 patients and 15 clinicians examinged the barriers and facilitators to hypertension control within a racially and ethnically diverse health care system.
JAMA Netw Open. 2023;6(2):e230977. doi:10.1001/jamanetworkopen.2023.0977
INFECTIOUS DISEASES
Ruchi Sharma, PhD; Wenzhe Zang, PhD; Ali Tabartehfarahani, PhD; et al.
This diagnostic study evaluates the accuracies of breath analysis on detecting patients with COVID-19 in periods when the Delta and Omicron variants were most prevalent.
JAMA Netw Open. 2023;6(2):e230982. doi:10.1001/jamanetworkopen.2023.0982
PEDIATRICS
Sarah D. Ronis, MD, MPH; David Selvaraj, MS; Jeffrey M. Albert, PhD; et al.
This cross-sectional study uses data from Pediatric Providers Against Cavities in Children’s Teeth study to investigate caries experience, including untreated decay, among Medicaid-enrolled preschoolers with or without special health care needs.
JAMA Netw Open. 2023;6(2):e230999. doi:10.1001/jamanetworkopen.2023.0999
CARDIOLOGY
C. Justin Brown, PharmD; Lee-Shing Chang, MD; Naoshi Hosomura, DDS, DMSc, MBA; et al.
This cohort study assesses sex disparities in nonacceptance of statin therapy and assess their association with low-density lipoprotein (LDL) cholesterol control.
JAMA Netw Open. 2023;6(2):e231047. doi:10.1001/jamanetworkopen.2023.1047
PUBLIC HEALTH
Julia P. Schleimer, MPH; Emma Gause, MS, MA; Kimberly Dalve, MA; et al.
This cross-sectional study examines differences in associations of adolescent interpersonal violence with handgun carrying across the rural-urban continuum.
JAMA Netw Open. 2023;6(2):e231153. doi:10.1001/jamanetworkopen.2023.1153
INFECTIOUS DISEASES
Margaret K. Doll, PhD, MPH; Alpana Waghmare, MD; Antje Heit, MD, PhD; et al.
This cohort study examines acute and postacute clinical outcomes of SARS-CoV-2 infection during the Delta and Omicron waves among previously immunologically naive adults.
JAMA Netw Open. 2023;6(2):e231181. doi:10.1001/jamanetworkopen.2023.1181