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October 2024 - May 2018

Decade

Year

Issue

February 2023, Vol 6, No. 2

open access Original Investigation

PEDIATRICS

Assessment of Pediatric Telemedicine Using Remote Physical Examinations With a Mobile Medical Device: A Nonrandomized Controlled Trial

This nonrandomized controlled trial assesses the concordance between measurements from a telemedicine physical examination using a mobile medical device and measurements from a conventional in-person physical examination among pediatric patients.

JAMA Netw Open. 2023;6(2):e2252570. doi:10.1001/jamanetworkopen.2022.52570
Abstract Full Text pdf link PDF

ENVIRONMENTAL HEALTH

Association of Long-term Exposure to Air Pollution With Late-Life Depression in Older Adults in the US

This cohort study investigates if long-term exposure to air pollution is associated with increased risk of late-life depression diagnosis among US older adults.

JAMA Netw Open. 2023;6(2):e2253668. doi:10.1001/jamanetworkopen.2022.53668
Abstract Full Text pdf link PDF

GERIATRICS

Comparing the Hospital Frailty Risk Score and the Clinical Frailty Scale Among Older Adults With Chronic Obstructive Pulmonary Disease Exacerbation

This cross-sectional study examines the agreement between the Hospital Frailty Risk Score and the Clinical Frailty Scale among hospitalized individuals with chronic obstructive pulmonary disease (COPD) and examines the sensitivity and specificity of the scales to detect frailty.

JAMA Netw Open. 2023;6(2):e2253692. doi:10.1001/jamanetworkopen.2022.53692
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association Between Antimicrobial Stewardship Programs and Antibiotic Use Globally: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis synthesizes current evidence regarding the association between antimicrobial stewardship programs and the consumption of antibiotics globally.

JAMA Netw Open. 2023;6(2):e2253806. doi:10.1001/jamanetworkopen.2022.53806
Abstract Full Text pdf link PDF

OTOLARYNGOLOGY

Synergistic Association of Hepatitis B Surface Antigen and Plasma Epstein-Barr Virus DNA Load on Distant Metastasis in Patients With Nasopharyngeal Carcinoma

This cohort study investigates the prognostic value and biological associations of hepatitis B surface antigen and plasma Epstein-Barr virus DNA levels with distant metastasis in patients with nasopharyngeal carcinoma.

JAMA Netw Open. 2023;6(2):e2253832. doi:10.1001/jamanetworkopen.2022.53832
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Reports of Guillain-Barré Syndrome After COVID-19 Vaccination in the United States

This cohort study investigates the association of Ad26.COV2.S, BNT162b2, and mRNA-1273 COVID-19 vaccination with rates of Guillain-Barré syndrome among US adults.

JAMA Netw Open. 2023;6(2):e2253845. doi:10.1001/jamanetworkopen.2022.53845
Abstract Full Text pdf link PDF

HEALTH POLICY

Assessment of Consumer Complaint Investigation Scores, Recertification Survey Scores, and Overall Nursing Home Health Inspection Star Quality Rating

This quality improvement study assesses star ratings that are specific to recertification surveys and ratings specific to complaint investigations for the purpose of assessing potential differences between the 2 components.

JAMA Netw Open. 2023;6(2):e2253952. doi:10.1001/jamanetworkopen.2022.53952
Abstract Full Text pdf link PDF

OPHTHALMOLOGY

Low Vision Rehabilitation Service Utilization Before and After Implementation of a Clinical Decision Support System in Ophthalmology

This quality improvement study evaluates low vision rehabilitation service use before and after implementation of an electronic health record–based clinical decision support system at a large ophthalmology department in an academic medical center.

JAMA Netw Open. 2023;6(2):e2254006. doi:10.1001/jamanetworkopen.2022.54006
Abstract Full Text pdf link PDF

NEPHROLOGY

Effectiveness of Mycophenolate Mofetil Among Patients With Progressive IgA Nephropathy: A Randomized Clinical Trial

This randomized clinical trial investigates the risk of kidney outcomes among patients with progressive IgA nephropathy receiving mycophenolate mofetil with supportive care vs supportive care alone.

JAMA Netw Open. 2023;6(2):e2254054. doi:10.1001/jamanetworkopen.2022.54054
Abstract Full Text pdf link PDF

PEDIATRICS

Reclassification of the Etiology of Infant Mortality With Whole-Genome Sequencing

This cohort study examines the association of genetic diseases with infant mortality at a large pediatric hospital system in San Diego County, California.

JAMA Netw Open. 2023;6(2):e2254069. doi:10.1001/jamanetworkopen.2022.54069
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Prevaccination Prevalence of Type-Specific Human Papillomavirus Infection by Grade of Cervical Cytology in Estonia

This cross-sectional study examines the prevaccination prevalence of high-risk human papillomavirus (HPV) and type distribution by cervical cytology grade in Estonia.

JAMA Netw Open. 2023;6(2):e2254075. doi:10.1001/jamanetworkopen.2022.54075
Abstract Full Text pdf link PDF

PEDIATRICS

Acoustic Cry Characteristics in Preterm Infants and Developmental and Behavioral Outcomes at 2 Years of Age

This cohort study evaluates the association between acoustic cry characteristics in preterm infants and developmental and behavioral outcomes at 2 years of age.

JAMA Netw Open. 2023;6(2):e2254151. doi:10.1001/jamanetworkopen.2022.54151
Abstract Full Text pdf link PDF

PEDIATRICS

Assessment of Cancer Predisposition Syndromes in a National Cohort of Children With a Neoplasm

This cohort study examines a Dutch national children’s cancer center’s experience in diagnosing cancer predisposition syndromes before introducing routine next-generation genetic sequencing.

JAMA Netw Open. 2023;6(2):e2254157. doi:10.1001/jamanetworkopen.2022.54157
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Clinical Importance of Clonal Hematopoiesis in Metastatic Gastrointestinal Tract Cancers

This cohort study assesses the association of clonal hematopoiesis with progression-free and overall survival among patients with metastatic colorectal and esophagogastric cancers who were undergoing treatment with first-line chemotherapy or immunotherapy.

JAMA Netw Open. 2023;6(2):e2254221. doi:10.1001/jamanetworkopen.2022.54221
Abstract Full Text pdf link PDF

PEDIATRICS

Assessment of Quality of Life of Transgender and Gender-Diverse Children and Adolescents in Melbourne, Australia, 2017-2020

This cohort study compares the quality of life of transgender and gender-diverse children and adolescents in Australia with that of their age-matched peers.

JAMA Netw Open. 2023;6(2):e2254292. doi:10.1001/jamanetworkopen.2022.54292
Abstract Full Text pdf link PDF

PEDIATRICS

Predictive Value of Early Autism Detection Models Based on Electronic Health Record Data Collected Before Age 1 Year

This diagnostic study evaluates the accuracy of early autism detection models based on electronic health record data collected before age 1 year.

JAMA Netw Open. 2023;6(2):e2254303. doi:10.1001/jamanetworkopen.2022.54303
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial

This randomized clinical trial investigates the physiological, behavioral, neural, and hormonal effects of kisspeptin administration in men with hypoactive sexual desire disorder.

JAMA Netw Open. 2023;6(2):e2254313. doi:10.1001/jamanetworkopen.2022.54313
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Rates of and Factors Associated With Primary and Booster COVID-19 Vaccine Receipt by US Veterans, December 2020 to June 2022

This cohort study examines factors associated with receipt of COVID-19 vaccination and rates of vaccination among US veterans.

JAMA Netw Open. 2023;6(2):e2254387. doi:10.1001/jamanetworkopen.2022.54387
Abstract Full Text pdf link PDF

MEDICAL JOURNALS AND PUBLISHING

Frequency and Characteristics of Trials Using Medical Writer Support in High-Impact Oncology Journals

This cross-sectional study reviews original oncology trials to assess whether the declared use of medical writers is associated with trial success and the use of a particular type of end point.

JAMA Netw Open. 2023;6(2):e2254405. doi:10.1001/jamanetworkopen.2022.54405
Abstract Full Text pdf link PDF

HEMATOLOGY

Comparisons of Severe Maternal Morbidity and Other Adverse Pregnancy Outcomes in Pregnant People With Sickle Cell Disease vs Anemia

This cross-sectional study compares rates and odds of severe maternal morbidity and other adverse pregnancy outcomes among Black pregnant individuals with sickle cell disease vs anemia.

JAMA Netw Open. 2023;6(2):e2254545. doi:10.1001/jamanetworkopen.2022.54545
Abstract Full Text pdf link PDF

HEMATOLOGY

Severe Maternal Morbidity and Mortality in Sickle Cell Disease in the National Inpatient Sample, 2012-2018

This cross-sectional study of deliveries in US hospitals examines pregnancy outcomes for people with sickle cell disease (SCD) and compares adverse outcomes with Black and Non-Black populations without SCD.

JAMA Netw Open. 2023;6(2):e2254552. doi:10.1001/jamanetworkopen.2022.54552
Abstract Full Text pdf link PDF

HEALTH POLICY

Association of Academic Medical Center Presence With Clinical Outcomes at Neighboring Community Hospitals Among Medicare Beneficiaries

This cohort study examines whether market-level academic medical center presence is associated with outcomes for Medicare patients treated at nonteaching hospitals within the same markets.

JAMA Netw Open. 2023;6(2):e2254559. doi:10.1001/jamanetworkopen.2022.54559
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Trends in Out-of-Pocket Costs for and Characteristics of Pharmacy-Dispensed Buprenorphine Medications for Opioid Use Disorder Treatment by Type of Payer, 2015 to 2020

This cross-sectional study evaluates trends in out-of-pocket costs for and characteristics of pharmacy-dispensed buprenorphine medications for opioid use disorder treatment by type of payer from 2015 to 2020.

JAMA Netw Open. 2023;6(2):e2254590. doi:10.1001/jamanetworkopen.2022.54590
Abstract Full Text pdf link PDF

ONCOLOGY

Factor Analysis of Health Care Access With Ovarian Cancer Surgery and Gynecologic Oncologist Consultation

This cohort study assesses health care affordability, availability, and accessibility along with race and ethnicity in association with receipt of guideline-adherent care for ovarian cancer.

JAMA Netw Open. 2023;6(2):e2254595. doi:10.1001/jamanetworkopen.2022.54595
Abstract Full Text pdf link PDF

SURGERY

Outcomes Among Undocumented Immigrant Kidney Transplant Recipients in California

This cohort study evaluates outcomes among undocumented immigrant kidney transplant recipients in California.

JAMA Netw Open. 2023;6(2):e2254660. doi:10.1001/jamanetworkopen.2022.54660
Abstract Full Text pdf link PDF

CARDIOLOGY

Association of Anthracycline With Heart Failure in Patients Treated for Breast Cancer or Lymphoma, 1985-2010

This case-control study compares the long-term incidence of congestive heart failure in patients treated for breast cancer or lymphoma with anthracycline therapy compared with healthy controls from the same community.

JAMA Netw Open. 2023;6(2):e2254669. doi:10.1001/jamanetworkopen.2022.54669
Abstract Full Text pdf link PDF

PSYCHIATRY

Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthy Adults: A Randomized Clinical Trial

This randomized clinical trial compares the pharmacokinetics and pharmacodynamics of orally administered Δ9-tetrahydrocannabinol (THC)-dominant and cannabidiol-dominant cannabis extracts that contained the same Δ9-THC dose in a healthy adult population of US adults.

JAMA Netw Open. 2023;6(2):e2254752. doi:10.1001/jamanetworkopen.2022.54752
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Patterns of Postpartum Primary Care Follow-up and Diabetes-Related Care After Diagnosis of Gestational Diabetes

This cohort study of US insurance claims data examines rates of appropriate postpartum primary care follow-up and diabetes-related care among patients who experienced gestational diabetes.

JAMA Netw Open. 2023;6(2):e2254765. doi:10.1001/jamanetworkopen.2022.54765
Abstract Full Text pdf link PDF

NEUROLOGY

Changes in Alcohol Consumption and Risk of Dementia in a Nationwide Cohort in South Korea

This cohort study investigates the association of comprehensive patterns of changes in alcohol consumption with the incidence of all-cause dementia, Alzheimer disease, and vascular dementia among individuals in Korea.

JAMA Netw Open. 2023;6(2):e2254771. doi:10.1001/jamanetworkopen.2022.54771
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Estimation of Vaccine Effectiveness of CoronaVac and BNT162b2 Against Severe Outcomes Over Time Among Patients With SARS-CoV-2 Omicron

This case-control study examines change over time in estimated vaccine effectiveness against hospitalization and mortality caused by the SARS-CoV-2 Omicron variant among adults in Hong Kong.

JAMA Netw Open. 2023;6(2):e2254777. doi:10.1001/jamanetworkopen.2022.54777
Abstract Full Text pdf link PDF

PEDIATRICS

Circulation of Rhinoviruses and/or Enteroviruses in Pediatric Patients With Acute Respiratory Illness Before and During the COVID-19 Pandemic in the US

This cross-sectional study describes the detection of rhinoviruses and/or enteroviruses by pediatric age group and health care setting.

JAMA Netw Open. 2023;6(2):e2254909. doi:10.1001/jamanetworkopen.2022.54909
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Patterns in the Prevalence of Unvaccinated Children Across 36 States and Union Territories in India, 1993-2021

This cross-sectional study uses data from National Family Health Surveys to examine patterns among children aged 12 to 23 months who have not received a single dose of the diphtheria-tetanus-pertussis vaccine across all states and union territories in India from 1993 to 2021.

JAMA Netw Open. 2023;6(2):e2254919. doi:10.1001/jamanetworkopen.2022.54919
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

US Medical School Admissions Leaders’ Experiences With Barriers to and Advancements in Diversity, Equity, and Inclusion

This qualitative study uses key-informant interviews to describe US medical school admissions leaders’ experiences with barriers to and advances in diversity, equity, and inclusion in admissions policies and processes.

JAMA Netw Open. 2023;6(2):e2254928. doi:10.1001/jamanetworkopen.2022.54928
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Modifiable Risk Factor Score and Fecundability in a Preconception Cohort in Singapore

This cohort study assesses the association between lifestyle factors and probability of conception within a menstrual cycle among females of reproductive age in Singapore.

JAMA Netw Open. 2023;6(2):e2255001. doi:10.1001/jamanetworkopen.2022.55001
Abstract Full Text pdf link PDF

ONCOLOGY

Gefitinib Plus Chemotherapy vs Gefitinib Alone in Untreated EGFR-Mutant Non–Small Cell Lung Cancer in Patients With Brain Metastases: The GAP BRAIN Open-Label, Randomized, Multicenter, Phase 3 Study

This randomized clinical trial compares the use of gefitinib plus chemotherapy with gefitinib monotherapy in patients with untreated EGFR-mutant non–small cell lung cancer brain metastases.

JAMA Netw Open. 2023;6(2):e2255050. doi:10.1001/jamanetworkopen.2022.55050
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Association of War With Vaccination Dropout Among Children Younger Than 2 Years in the North Wollo Zone, Ethiopia

This cross-sectional study assesses the association of war with vaccination dropout among children younger than 2 years in the North Wollo zone of Ethiopia.

JAMA Netw Open. 2023;6(2):e2255098. doi:10.1001/jamanetworkopen.2022.55098
Abstract Full Text pdf link PDF

PHARMACY AND CLINICAL PHARMACOLOGY

Association Between Opioid Tapering and Subsequent Health Care Use, Medication Adherence, and Chronic Condition Control

This cohort study examines outcomes associated with tapering of opioid therapy in patients who have received stable doses for 1 year, including subcohorts of those with hypertension or diabetes.

JAMA Netw Open. 2023;6(2):e2255101. doi:10.1001/jamanetworkopen.2022.55101
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Perspectives of US Youths on Participation of Transgender Individuals in Competitive Sports: A Qualitative Study

This qualitative study surveys adolescents and young adults in the US to assess their experiences and perspectives on the inclusion of transgender individuals in competitive sports.

JAMA Netw Open. 2023;6(2):e2255107. doi:10.1001/jamanetworkopen.2022.55107
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Strategies and Best Practices to Improve Diversity, Equity, and Inclusion Among US Graduate Medical Education Programs

This qualitative study performs an exploratory content analysis to investigate what strategies and best practices are used by graduate medical education programs to improve diversity, equity, and inclusion in their programs with detailed narratives from residency program applicants.

JAMA Netw Open. 2023;6(2):e2255110. doi:10.1001/jamanetworkopen.2022.55110
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Comparison of Chest Radiograph Captions Based on Natural Language Processing vs Completed by Radiologists

This diagnostic study evaluates chest radiography captions generated by natural language processing compared with the diagnostic findings of radiologists.

JAMA Netw Open. 2023;6(2):e2255113. doi:10.1001/jamanetworkopen.2022.55113
Abstract Full Text pdf link PDF

PEDIATRICS

Level of Attention to Motherese Speech as an Early Marker of Autism Spectrum Disorder

This diagnostic study investigates whether attention to high-affect motherese speech can be used as a diagnostic marker of autism spectrum disorder and language and social ability among toddlers aged 12 to 48 months.

JAMA Netw Open. 2023;6(2):e2255125. doi:10.1001/jamanetworkopen.2022.55125
Abstract Full Text pdf link PDF

GERIATRICS

Risk of Discharge to Lower-Quality Nursing Homes Among Hospitalized Older Adults With Alzheimer Disease and Related Dementias

This cross-sectional study investigates whether hospitalized older adults with Alzheimer disease and related dementias are more likely to be discharged to lower-quality skilled nursing facilities following hospitalization.

JAMA Netw Open. 2023;6(2):e2255134. doi:10.1001/jamanetworkopen.2022.55134
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Unilateral Radiotherapy With Contralateral Lymph Node Failure Among Patients With Squamous Cell Carcinoma of the Tonsil: A Systematic Review and Meta-analysis

This systematic review and meta-analysis assesses the risk of nodal failure within the contralateral nonirradiated neck after ipsilateral neck radiotherapy in patients with tonsil cancer.

JAMA Netw Open. 2023;6(2):e2255209. doi:10.1001/jamanetworkopen.2022.55209
Abstract Full Text pdf link PDF

HEALTH POLICY

Financial Toxicity Among Patients With Breast Cancer Worldwide: A Systematic Review and Meta-analysis

This systematic review and meta-analysis examines the rate of financial toxicity among patients with breast cancer worldwide.

JAMA Netw Open. 2023;6(2):e2255388. doi:10.1001/jamanetworkopen.2022.55388
Abstract Full Text pdf link PDF

ONCOLOGY

Association of Modifiable Health Conditions and Social Determinants of Health With Late Mortality in Survivors of Childhood Cancer

This cohort study uses data from the St Jude Lifetime Cohort to assess the association of modifiable chronic health conditions and socioeconomic factors with late mortality among adult survivors of childhood cancer.

JAMA Netw Open. 2023;6(2):e2255395. doi:10.1001/jamanetworkopen.2022.55395
Abstract Full Text pdf link PDF

SURGERY

Patient Characteristics Associated With Occurrence of Preoperative Goals-of-Care Conversations

This cross-sectional study evaluates the association between patient risk of hospitalization or death and goals-of-care conversations documented with a completed Life Sustaining Treatment Decisions Initiative note among individuals undergoing surgery in the Veterans Health Administration.

JAMA Netw Open. 2023;6(2):e2255407. doi:10.1001/jamanetworkopen.2022.55407
Abstract Full Text pdf link PDF

PEDIATRICS

Effect of Silver Diamine Fluoride on Caries Arrest and Prevention: The CariedAway School-Based Randomized Clinical Trial

This randomized clinical trial assessed the noninferiority of silver diamine fluoride with fluoride varnish vs traditional glass ionomer sealants with fluoride varnish after 2 years when provided to children via a school-based health care program.

JAMA Netw Open. 2023;6(2):e2255458. doi:10.1001/jamanetworkopen.2022.55458
Abstract Full Text pdf link PDF

PEDIATRICS

Association of Physical Activity and Screen Time With Body Mass Index Among US Adolescents

This cross-sectional study uses data from the Adolescent Brain Cognitive Development Study to assess the association of physical activity and screen time with overweight or obesity among adolescents in the US.

JAMA Netw Open. 2023;6(2):e2255466. doi:10.1001/jamanetworkopen.2022.55466
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Association of Recent SARS-CoV-2 Infection With New-Onset Alcohol Use Disorder, January 2020 Through January 2022

This cohort study uses electronic health records of 2 821 182 US patients to examine associations of a new diagnosis of alcohol use disorder with COVID-19 over time from January 2020 through January 2022.

JAMA Netw Open. 2023;6(2):e2255496. doi:10.1001/jamanetworkopen.2022.55496
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Breast and Lung Cancer Screening Among Medicare Enrollees During the COVID-19 Pandemic

This cohort study examines the observed vs expected mammography and low-dose computed tomographic scan rates from the beginning of the COVID-19 pandemic through April 2022.

JAMA Netw Open. 2023;6(2):e2255589. doi:10.1001/jamanetworkopen.2022.55589
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Hospital Outcomes of Community-Acquired SARS-CoV-2 Omicron Variant Infection Compared With Influenza Infection in Switzerland

This cohort study compares in-hospital outcomes among patients hospitalized with the SARS-CoV-2 Omicron variant vs those hospitalized with influenza A or B in Switzerland.

JAMA Netw Open. 2023;6(2):e2255599. doi:10.1001/jamanetworkopen.2022.55599
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Accuracy of Gallium-68 Pentixafor Positron Emission Tomography–Computed Tomography for Subtyping Diagnosis of Primary Aldosteronism

This diagnostic study investigates the accuracy of gallium-68 pentixafor positron emission tomography–computed tomography vs adrenal vein sampling in subtyping diagnosis of primary aldosteronism.

JAMA Netw Open. 2023;6(2):e2255609. doi:10.1001/jamanetworkopen.2022.55609
Abstract Full Text pdf link PDF

CARDIOLOGY

Effect of a Telephone Health Coaching Intervention on Hypertension Control in Young Adults: The MyHEART Randomized Clinical Trial

This randomized clinical trial evaluates the effect of the My Hypertension Education And Reaching Target (MyHEART) intervention, a telephone coaching and blood pressure self-monitoring program, compared with usual care on changes in systolic and diastolic blood pressures and behaviors at 6 and 12 months among young adults with uncontrolled hypertension.

JAMA Netw Open. 2023;6(2):e2255618. doi:10.1001/jamanetworkopen.2022.55618
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Association of Perceived Neighborhood Health With Hypertension Self-care

This cross-sectional study examines hypertension self-management in Black individuals in socially disadvantaged settings.

JAMA Netw Open. 2023;6(2):e2255626. doi:10.1001/jamanetworkopen.2022.55626
Abstract Full Text pdf link PDF

PEDIATRICS

Bidirectional Associations Between Adiposity and Cognitive Function and Mediation by Brain Morphology in the ABCD Study

This cohort study assesses bidirectional associations between adiposity and cognitive function in youth in the United States and tests mediational pathways through the lateral prefrontal cortext.

JAMA Netw Open. 2023;6(2):e2255631. doi:10.1001/jamanetworkopen.2022.55631
Abstract Full Text pdf link PDF

PEDIATRICS

Association of Expanded Child Tax Credit Payments With Child Abuse and Neglect Emergency Department Visits

This cross-sectional study evaluates the association between the 2021 expanded child tax credit payments and child abuse and neglect emergency department (ED) visits.

JAMA Netw Open. 2023;6(2):e2255639. doi:10.1001/jamanetworkopen.2022.55639
Abstract Full Text pdf link PDF

GERIATRICS

Comparison of Fractures Among Older Adults Who Are Ambulatory vs Those Who Use Wheelchairs in Sweden

This nationwide cohort study investigates whether immobilized patients who use wheelchairs have a different risk of fracture and injurious falls compared with a matched control group of ambulatory adults in Sweden.

JAMA Netw Open. 2023;6(2):e2255645. doi:10.1001/jamanetworkopen.2022.55645
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Effect of Fractional Carbon Dioxide vs Sham Laser on Sexual Function in Survivors of Breast Cancer Receiving Aromatase Inhibitors for Genitourinary Syndrome of Menopause: The LIGHT Randomized Clinical Trial

This randomized clinical trial assesses the safety and efficacy of carbon dioxide (CO2) vs sham vaginal laser treatment after 6 months of follow-up in survivors of breast cancer receiving aromatase inhibitors with genitourinary syndrome of menopause.

JAMA Netw Open. 2023;6(2):e2255697. doi:10.1001/jamanetworkopen.2022.55697
Abstract Full Text pdf link PDF

CARDIOLOGY

Effect of Rivaroxaban vs Enoxaparin on Major Cardiac Adverse Events and Bleeding Risk in the Acute Phase of Acute Coronary Syndrome: The H-REPLACE Randomized Equivalence and Noninferiority Trial

This randomized equivalence and noninferiority trial compares safety and efficacy of enoxaparin vs rivaroxaban 2.5 or 5 mg for patients with acute coronary syndrome (ACS) in the acute phase.

JAMA Netw Open. 2023;6(2):e2255709. doi:10.1001/jamanetworkopen.2022.55709
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Safety and Tolerability of SER-109 as an Investigational Microbiome Therapeutic in Adults With Recurrent Clostridioides difficile Infection: A Phase 3, Open-Label, Single-Arm Trial

This phase 3, open-label, single-arm trial assesses the safety of SER-109 and the rate of recurrent Clostridioides difficile infection after administration of SER-109 following symptom resolution after antibiotic treatment among adults.

JAMA Netw Open. 2023;6(2):e2255758. doi:10.1001/jamanetworkopen.2022.55758
Abstract Full Text pdf link PDF

PEDIATRICS

Impact of Tele-Emergency Consultations on Pediatric Interfacility Transfers: A Cluster-Randomized Crossover Trial

This cluster randomized trial examines the use of telemedicine by pediatric referral centers to reduce the frequency of interfacility transfers among acutely ill children presenting to rural and community emergency departments.

JAMA Netw Open. 2023;6(2):e2255770. doi:10.1001/jamanetworkopen.2022.55770
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Incidence, Risk, and Severity of SARS-CoV-2 Reinfections in Children and Adolescents Between March 2020 and July 2022 in Serbia

This cohort study of children and adolescents in Vojvodina, Serbia, assesses the reinfection risk of SARS-CoV-2.

JAMA Netw Open. 2023;6(2):e2255779. doi:10.1001/jamanetworkopen.2022.55779
Abstract Full Text pdf link PDF

ORTHOPEDICS

Comparison of Distal Radius Fracture Outcomes in Older Adults Stratified by Chronologic vs Physiologic Age Managed With Casting vs Surgery

This secondary analysis of the Wrist and Radius Injury Surgical Trial examines differences in outcomes after distal radius fracture managed with casting vs surgery in patients stratified by physiologic vs chronologic age.

JAMA Netw Open. 2023;6(2):e2255786. doi:10.1001/jamanetworkopen.2022.55786
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Assessment of Symptom, Disability, and Financial Trajectories in Patients Hospitalized for COVID-19 at 6 Months

This cohort study evaluates long-term physical and financial outcomes of individuals who were hospitalized with COVID-19.

JAMA Netw Open. 2023;6(2):e2255795. doi:10.1001/jamanetworkopen.2022.55795
Abstract Full Text pdf link PDF

OPHTHALMOLOGY

Early vs Deferred Non–Messenger RNA COVID-19 Vaccination Among Chinese Patients With a History of Inactive Uveitis: A Randomized Clinical Trial

This randomized clinical trial compares recommendations for early and deferred non–messenger RNA COVID-19 vaccination with respect to ocular outcomes among patients with inactive uveitis.

JAMA Netw Open. 2023;6(2):e2255804. doi:10.1001/jamanetworkopen.2022.55804
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Identification of Bradycardia Following Remdesivir Administration Through the US Food and Drug Administration American College of Medical Toxicology COVID-19 Toxic Pharmacovigilance Project

This cohort study examines the incidence of bradycardia occurring during or after administration of remdesivir in patients with COVID-19 through the US Food and Drug Administration American College of Medical Toxicology COVID-19 Toxic (FACT) Pharmacovigilance Project.

JAMA Netw Open. 2023;6(2):e2255815. doi:10.1001/jamanetworkopen.2022.55815
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Association of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction

This cohort study of patients with acute myocardial infarction (AMI) assesses whether race and social determinants of health are associated with hospital readmission rates within 1 year of discharge.

JAMA Netw Open. 2023;6(2):e2255843. doi:10.1001/jamanetworkopen.2022.55843
Abstract Full Text pdf link PDF

GERIATRICS

Emergency Department and Hospital Utilization Among Older Adults Before and After Identification of Elder Mistreatment

This case-control study uses Medicare claims data to examine emergency department and hospital utilization among older adults experiencing elder mistreatment during the period surrounding initial mistreatment identification compared with that of other older adults.

JAMA Netw Open. 2023;6(2):e2255853. doi:10.1001/jamanetworkopen.2022.55853
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Seroprevalence of Antibodies to SARS-CoV-2 in Rural Households in Eastern Uganda, 2020-2022

This cohort study estimates SARS-CoV-2 seroprevalence, attack rates, and reinfection in rural eastern Uganda using serologic surveillance from 2020 to early 2022.

JAMA Netw Open. 2023;6(2):e2255978. doi:10.1001/jamanetworkopen.2022.55978
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PEDIATRICS

Prediction of Suicide Attempts and Suicide-Related Events Among Adolescents Seen in Emergency Departments

This cohort study compares the Ask Suicide-Screening Questions instrument with the Computerized Adaptive Screen for Suicidal Youth instrument for the prediction of suicidal behavior among adolescents seen in emergency departments (EDs), across demographic and clinical strata.

JAMA Netw Open. 2023;6(2):e2255986. doi:10.1001/jamanetworkopen.2022.55986
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SURGERY

Clinical Outcomes and Hospital Utilization Among Patients Undergoing Bariatric Surgery With Telemedicine Preoperative Care

This cohort study conducted at a US academic hospital compares clinical outcomes and follow-up hospitalization of patients receiving bariatric surgery utilizing telemedicine for preoperative care with an in-person control group.

JAMA Netw Open. 2023;6(2):e2255994. doi:10.1001/jamanetworkopen.2022.55994
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HEALTH POLICY

Comparison of Simulated Outcomes of Colorectal Cancer Surgery at the Highest-Performing vs Chosen Local Hospitals

This economic evaluation assesses the association of hospital referral choices with mortality risk, and the cost of these choices, in adults who underwent colorectal resection.

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JAMA Netw Open. 2023;6(2):e2255999. doi:10.1001/jamanetworkopen.2022.55999
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SURGERY

Effect of Laparoscopic Proximal Gastrectomy With Double-Tract Reconstruction vs Total Gastrectomy on Hemoglobin Level and Vitamin B12 Supplementation in Upper-Third Early Gastric Cancer: A Randomized Clinical Trial

This randomized clinical trial assesses whether laparoscopic proximal gastrectomy with double-tract reconstruction is superior to laparoscopic total gastrectomy for the surgical treatment of patients with early gastric cancer in the upper third of the stomach.

JAMA Netw Open. 2023;6(2):e2256004. doi:10.1001/jamanetworkopen.2022.56004
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HEALTH POLICY

Factors Associated With Primary Care Physician Decision-making When Making Medication Recommendations vs Surgical Referrals

This qualitative study describes the factors primary care physicians report considering when deciding whether to offer patients prescription medication vs a surgical referral.

JAMA Netw Open. 2023;6(2):e2256086. doi:10.1001/jamanetworkopen.2022.56086
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PUBLIC HEALTH

Association of Post–COVID-19 Condition Symptoms and Employment Status

This survey study evaluates the association of post–COVID-19 condition symptoms with employment status.

JAMA Netw Open. 2023;6(2):e2256152. doi:10.1001/jamanetworkopen.2022.56152
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PEDIATRICS

Trends in Screen Time Use Among Children During the COVID-19 Pandemic, July 2019 Through August 2021

This cohort study evaluates changes in children’s screen time from before the pandemic to during the pandemic, from July 2019 through August 2021.

JAMA Netw Open. 2023;6(2):e2256157. doi:10.1001/jamanetworkopen.2022.56157
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HEALTH POLICY

Regulatory Approval, Reimbursement, and Clinical Use of Cyclin-Dependent Kinase 4/6 Inhibitors in Metastatic Breast Cancer in the Netherlands

This cohort study examines the postapproval processes and timing for making palbociclib, ribociclib, and abemaciclib available to patients with metastatic breast cancer in a high-income country.

JAMA Netw Open. 2023;6(2):e2256170. doi:10.1001/jamanetworkopen.2022.56170
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PEDIATRICS

Trends in In-Hospital Cardiac Arrest and Mortality Among Children With Cardiac Disease in the Intensive Care Unit: A Systematic Review and Meta-analysis

This systematic review and meta-analysis investigates incidence, trends, and factors associated with in-hospital cardiac arrest (IHCA) and mortality in children with cardiac disease in the intensive care unit (ICU).

JAMA Netw Open. 2023;6(2):e2256178. doi:10.1001/jamanetworkopen.2022.56178
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NUTRITION, OBESITY, AND EXERCISE

Association of Accelerometer-Measured Physical Activity Level With Risks of Hospitalization for 25 Common Health Conditions in UK Adults

This cohort study uses accelerometer data from UK Biobank participants to examine the association between physical activity and the risks of hospitalization for 25 common conditions and to estimate the proportion of hospitalizations that may be preventable with higher activity levels.

JAMA Netw Open. 2023;6(2):e2256186. doi:10.1001/jamanetworkopen.2022.56186
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MEDICAL EDUCATION

Identifying Value Factors in Institutional Leaders’ Perspectives on Investing in Health Professions Educators

This qualitative study explores the value factors that health professional leaders placed on educator investment programs, including intramural grants and endowed chairs, through interviews at an urban academic health professions institute in the US.

JAMA Netw Open. 2023;6(2):e2256193. doi:10.1001/jamanetworkopen.2022.56193
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OBSTETRICS AND GYNECOLOGY

Severe Maternal Morbidity and Mortality Among Immigrant and Canadian-Born Women Residing Within Low-Income Neighborhoods in Ontario, Canada

This population-based cohort study compares the risk of severe maternal morbidity or mortality between immigrant and nonimmigrant women residing exclusively within low-income neighborhoods in Ontario, Canada.

JAMA Netw Open. 2023;6(2):e2256203. doi:10.1001/jamanetworkopen.2022.56203
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PUBLIC HEALTH

Vaccination Intention Following Receipt of Vaccine Information Through Interactive Simulation vs Text Among COVID-19 Vaccine–Hesitant Adults During the Omicron Wave in Germany

This cross-sectional study evaluates the vaccination intentions of COVID-19 vaccine hesitant adults during the Omicron wave in Germany following receipt of vaccine information through interactive simulation vs text.

JAMA Netw Open. 2023;6(2):e2256208. doi:10.1001/jamanetworkopen.2022.56208
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PEDIATRICS

Effects of an Immersive Virtual Reality Intervention on Pain and Anxiety Among Pediatric Patients Undergoing Venipuncture: A Randomized Clinical Trial

This randomized clinical trial examines the effects of immersive virtual reality on reducing the pain, anxiety, and stress experienced by pediatric patients undergoing venipuncture.

JAMA Netw Open. 2023;6(2):e230001. doi:10.1001/jamanetworkopen.2023.0001
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ONCOLOGY

Validation of the ONKOTEV Risk Prediction Model for Venous Thromboembolism in Outpatients With Cancer

This prognostic study assesses the ONKOTEV score as a novel risk assessment model to evaluate the risk of venous thromboembolism (VTE) among outpatients with cancer.

JAMA Netw Open. 2023;6(2):e230010. doi:10.1001/jamanetworkopen.2023.0010
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ONCOLOGY

Assessment of Social Vulnerability in Pediatric Head and Neck Cancer Care and Prognosis in the United States

This cohort study evaluates the association of overall social vulnerability and specific social determinants of health with disparities in head and neck cancer care and prognosis among children and adolescents in the United States.

JAMA Netw Open. 2023;6(2):e230016. doi:10.1001/jamanetworkopen.2023.0016
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PEDIATRICS

Monoclonal Antibody for the Prevention of Respiratory Syncytial Virus in Infants and Children: A Systematic Review and Network Meta-analysis

This systematic review and network meta-analysis compares the efficacy and safety of 4 monoclonal antibodies for preventing respiratory syncytial virus among infants and children.

JAMA Netw Open. 2023;6(2):e230023. doi:10.1001/jamanetworkopen.2023.0023
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CARDIOLOGY

Association of Hypertensive Disorders of Pregnancy With Future Cardiovascular Disease

This genetic association study uses mendelian randomization to examine factors associated with long-term outcomes of hypertensive disorders in pregnancy.

JAMA Netw Open. 2023;6(2):e230034. doi:10.1001/jamanetworkopen.2023.0034
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GLOBAL HEALTH

Implementation of a Multimodal Knowledge-Exchange Platform to Provide Trauma Critical Care Education During the Ongoing Conflict in Ukraine

This quality improvement study describes the development and implementation of a multimodal trauma critical care knowledge-exchange platform during the ongoing conflict in Ukraine and evaluates the reach of this intervention, together with participant engagement and satisfaction.

JAMA Netw Open. 2023;6(2):e230050. doi:10.1001/jamanetworkopen.2023.0050
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GERIATRICS

Antipsychotic Medication Use Among Older Adults Following Infection-Related Hospitalization

This cohort study assesses antipsychotic medication use among older US adults, including rates of and patient characteristics associated with discontinuation, following infection-related hospitalization.

JAMA Netw Open. 2023;6(2):e230063. doi:10.1001/jamanetworkopen.2023.0063
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PUBLIC HEALTH

Association of Conditional Cash Transfers With Maternal Mortality Using the 100 Million Brazilian Cohort

This cohort study uses national Brazilian linked data from health and social administrative databases to investigate the association between the Bolsa Família conditional cash transfer program and maternal mortality among women and girls of child-bearing age.

JAMA Netw Open. 2023;6(2):e230070. doi:10.1001/jamanetworkopen.2023.0070
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DIABETES AND ENDOCRINOLOGY

Association of Achieving Time in Range Clinical Targets With Treatment Modality Among Youths With Type 1 Diabetes

This cohort study evaluates the the association of different treatment modalities with achieving recommended glucose levels in a large, diverse, international cohort of children, adolescents, and young adults with type 1 diabetes.

JAMA Netw Open. 2023;6(2):e230077. doi:10.1001/jamanetworkopen.2023.0077
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ONCOLOGY

Evaluation of Concomitant Systemic Treatment in Older Adults With Head and Neck Squamous Cell Carcinoma Undergoing Definitive Radiotherapy

This cohort study examines the outcomes of adding chemotherapy or cetuximab to radiotherapy treatment in older adults with locoregionally advanced head and neck squamous cell carcinoma.

JAMA Netw Open. 2023;6(2):e230090. doi:10.1001/jamanetworkopen.2023.0090
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ONCOLOGY

Effect of Epirubicin Plus Paclitaxel vs Epirubicin and Cyclophosphamide Followed by Paclitaxel on Disease-Free Survival Among Patients With Operable ERBB2-Negative and Lymph Node–Positive Breast Cancer: A Randomized Clinical Trial

This randomized clinical trial compares the long-term efficacy and toxic effects of epirubicin plus paclitaxel and the standard epirubicin and cyclophosphamide followed by paclitaxel regimen among women with ERBB2-negative, lymph node–positive breast cancer.

JAMA Netw Open. 2023;6(2):e230122. doi:10.1001/jamanetworkopen.2023.0122
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PEDIATRICS

Evaluation of Maternal Infection During Pregnancy and Childhood Leukemia Among Offspring in Denmark

This cohort study used national registry data for all children born in Denmark between 1978 to 2015 to examine the association of maternal infection during pregnancy with childhood leukemia among offspring.

JAMA Netw Open. 2023;6(2):e230133. doi:10.1001/jamanetworkopen.2023.0133
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HEALTH POLICY

Association of Skilled Nursing Facility Ownership by Health Care Networks With Utilization and Spending

This cross-sectional study assesses differences in surgical outcomes and spending for Medicare beneficiaries undergoing elective hip replacement procedures in hospital networks that have vertical integration of skilled nursing facilities vs those that do not.

JAMA Netw Open. 2023;6(2):e230140. doi:10.1001/jamanetworkopen.2023.0140
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PSYCHIATRY

Effect of Adjunctive Simvastatin on Depressive Symptoms Among Adults With Treatment-Resistant Depression: A Randomized Clinical Trial

This randomized clinical trial of adults with treatment-resistant depression assesses whether adjunctive simvastatin therapy improves depressive symptoms compared with placebo.

JAMA Netw Open. 2023;6(2):e230147. doi:10.1001/jamanetworkopen.2023.0147
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PEDIATRICS

Measures of Brain Connectivity and Cognition by Sex in US Children

This cross-sectional study of US children aged 9 to 11 years assesses functional connectivity hubs displaying prominent sex differences and the association between global functional connectivity density and total cognitive scores.

JAMA Netw Open. 2023;6(2):e230157. doi:10.1001/jamanetworkopen.2023.0157
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ONCOLOGY

Cumulative 6-Year Risk of Screen-Detected Ductal Carcinoma In Situ by Screening Frequency

This cohort study of US women aged 40 to 74 years undergoing mammography screening uses a risk prediction model to determine the cumulative 6-year risk of screen-detected ductal carcinoma in situ.

JAMA Netw Open. 2023;6(2):e230166. doi:10.1001/jamanetworkopen.2023.0166
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OBSTETRICS AND GYNECOLOGY

Association of the COVID-19 Pandemic With Unstable and/or Unsafe Living Situations and Intimate Partner Violence Among Pregnant Individuals

This cross-sectional study compares the rates of unstable and/or unsafe living situations and intimate partner violence in individuals who were pregnant before vs during the COVID-19 pandemic.

JAMA Netw Open. 2023;6(2):e230172. doi:10.1001/jamanetworkopen.2023.0172
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ONCOLOGY

Association of Neighborhood-Level Household Income With 21-Gene Recurrence Score and Survival Among Patients With Estrogen Receptor–Positive Breast Cancer

This cohort study of US women with estrogen receptor (ER)-positive breast cancer examines the association of income levels with 21-gene recurrence scores and survival outcomes.

JAMA Netw Open. 2023;6(2):e230179. doi:10.1001/jamanetworkopen.2023.0179
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STATISTICS AND RESEARCH METHODS

Using Haplotype-Based Artificial Intelligence to Evaluate SARS-CoV-2 Novel Variants and Mutations

This cross-sectional study investigates the use of haplotype-based artificial intelligence to identify novel SARS-COV-2 variants and mutations.

JAMA Netw Open. 2023;6(2):e230191. doi:10.1001/jamanetworkopen.2023.0191
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ENVIRONMENTAL HEALTH

Exposure to Air Pollution and Emergency Department Visits During the First Year of Life Among Preterm and Full-term Infants

This cohort study examines the association of air pollution exposure and emergency department visits in the first year of life in full-term and preterm infants in California.

JAMA Netw Open. 2023;6(2):e230262. doi:10.1001/jamanetworkopen.2023.0262
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COMPLEMENTARY AND ALTERNATIVE MEDICINE

Effects of Electroacupuncture for Opioid-Induced Constipation in Patients With Cancer in China: A Randomized Clinical Trial

This randomized clinical trial assesses the effect of electroacupuncture for opioid-induced constipation in patients with cancer in China.

JAMA Netw Open. 2023;6(2):e230310. doi:10.1001/jamanetworkopen.2023.0310
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CRITICAL CARE MEDICINE

Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors: A Secondary Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Randomized Clinical Trial

This secondary analysis of a randomized clinical trial reports on the cognitive performance, risk of posttraumatic stress disorder and depression, and functional status 6 months after the administration of a treatment regimen consisting of antioxidants and hydrocortisone infusion in adults with sepsis.

JAMA Netw Open. 2023;6(2):e230380. doi:10.1001/jamanetworkopen.2023.0380
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ONCOLOGY

Incidence of Aggressive End-of-Life Care Among Older Adults With Metastatic Cancer Living in Nursing Homes and Community Settings

This cohort study uses data from the Surveillance, Epidemiology, and End Results database to compare markers of aggressive end-of-life care between older adults with metastatic cancer who are nursing home residents and their community-dwelling counterparts.

JAMA Netw Open. 2023;6(2):e230394. doi:10.1001/jamanetworkopen.2023.0394
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ONCOLOGY

Association Between Survival and Metastatic Site in Mismatch Repair–Deficient Metastatic Colorectal Cancer Treated With First-line Pembrolizumab

This cohort study assesses the clinicopathological features, outcomes, and adverse events of older patients with metastatic colorectal adenocarcinomas.

JAMA Netw Open. 2023;6(2):e230400. doi:10.1001/jamanetworkopen.2023.0400
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STATISTICS AND RESEARCH METHODS

Use of Bayesian Statistics to Reanalyze Data From the Pragmatic Randomized Optimal Platelet and Plasma Ratios Trial

This quality improvement study describes the outcomes of bayesian statistical approaches using data from the Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial.

JAMA Netw Open. 2023;6(2):e230421. doi:10.1001/jamanetworkopen.2023.0421
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OBSTETRICS AND GYNECOLOGY

Characteristics of Maternal Mortality Missed by Vital Statistics in Hong Kong, 2000-2019

This cross-sectional study assesses causes and timing of maternal death in Hong Kong and identifies deaths and their causes that were missed by the vital statistics database.

JAMA Netw Open. 2023;6(2):e230429. doi:10.1001/jamanetworkopen.2023.0429
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DIABETES AND ENDOCRINOLOGY

Sodium-Glucose Transport Protein 2 Inhibitor Use for Type 2 Diabetes and the Incidence of Acute Kidney Injury in Taiwan

This cohort study investigates the association of sodium-glucose transport protein 2 inhibitor (SGLT2i) use and the incidence of acute kidney injury (AKI) in patients with type 2 diabetes in Taiwan.

JAMA Netw Open. 2023;6(2):e230453. doi:10.1001/jamanetworkopen.2023.0453
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INFECTIOUS DISEASES

Association of Proton Pump Inhibitor Use With Risk of Acquiring Drug-Resistant Enterobacterales

This case-control study assesses the association between the use of proton pump inhibitors and the risk of acquiring drug-resistant Enterobacterales and examines interactions with possible microbiome-altering agents among adult hospitalized patients.

JAMA Netw Open. 2023;6(2):e230470. doi:10.1001/jamanetworkopen.2023.0470
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ONCOLOGY

Association of Brain Metastases With Survival in Patients With Limited or Stable Extracranial Disease: A Systematic Review and Meta-analysis

This meta-analysis evaluates overall survival, progression-free survival, and intracranial progression-free survival in patients with stable vs progressive intracranial metastatic disease secondary to any primary cancer.

JAMA Netw Open. 2023;6(2):e230475. doi:10.1001/jamanetworkopen.2023.0475
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SURGERY

Characterizing Moral Injury and Distress in US Military Surgeons Deployed to Far-Forward Combat Environments in Afghanistan and Iraq

This qualitative study examines moral injury and distress among US military surgeons deployed to Iraq and Afghanistan during periods of high casualty volumes through a mixed-methods approach.

JAMA Netw Open. 2023;6(2):e230484. doi:10.1001/jamanetworkopen.2023.0484
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HEALTH POLICY

Multinational Analysis of Estimated Health Care Costs Related to Extended-Interval Fixed Dosing of Checkpoint Inhibitors

This economic evaluation estimates the health care costs associated with using extended-interval fixed dosing instead of standard-interval fixed dosing of immune checkpoint inhibitors in a simulated cohort of patients with urothelial cancer.

JAMA Netw Open. 2023;6(2):e230490. doi:10.1001/jamanetworkopen.2023.0490
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HEALTH INFORMATICS

A Competition, Benchmark, Code, and Data for Using Artificial Intelligence to Detect Lesions in Digital Breast Tomosynthesis

This diagnostic study describes a grand challenge for using artificial intelligence (AI) to detect cancer in digital breast tomosynthesis images.

JAMA Netw Open. 2023;6(2):e230524. doi:10.1001/jamanetworkopen.2023.0524
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INFECTIOUS DISEASES

Detection of the Omicron BA.1 Variant of SARS-CoV-2 in Wastewater From a Las Vegas Tourist Area

This cross-sectional study leverages spatial and temporal differences in wastewater whole-genome sequencing data to quantify relative SARS-CoV-2 contributions from visitors to southern Nevada.

JAMA Netw Open. 2023;6(2):e230550. doi:10.1001/jamanetworkopen.2023.0550
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ENVIRONMENTAL HEALTH

Association of Long-term Exposure to Particulate Air Pollution With Cardiovascular Events in California

This cohort study examines associations between long-term fine particulate air pollution and cardiovascular events using electronic health record and geocoded address data.

JAMA Netw Open. 2023;6(2):e230561. doi:10.1001/jamanetworkopen.2023.0561
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ONCOLOGY

Risk Prediction Models for Cardiotoxicity of Chemotherapy Among Patients With Breast Cancer: A Systematic Review

This systematic review evaluates risk prediction models of cardiotoxicity for patients with breast cancer.

JAMA Netw Open. 2023;6(2):e230569. doi:10.1001/jamanetworkopen.2023.0569
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INFECTIOUS DISEASES

Transmission of COVID-19 in Nightlife, Household, and Health Care Settings in Tokyo, Japan, in 2020

This case series describes the characteristics of COVID-19 transmission within different social settings in Tokyo, Japan, and evaluates which settings are associated with onward transmission.

JAMA Netw Open. 2023;6(2):e230589. doi:10.1001/jamanetworkopen.2023.0589
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ONCOLOGY

Evaluation of Systemic Treatments of Small Intestinal Adenocarcinomas: A Systematic Review and Meta-analysis

This systematic review and meta-analysis explores the survival benefit associated with systemic treatment in patients with small intestinal adenocarcinomas.

JAMA Netw Open. 2023;6(2):e230631. doi:10.1001/jamanetworkopen.2023.0631
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ONCOLOGY

Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility

This case-control study pools and analyzes individual-level data from 8 Ovarian Cancer Association Consortium case-control studies to evaluate whether a polygenic score modifies the association of frequent aspirin use with ovarian cancer.

JAMA Netw Open. 2023;6(2):e230666. doi:10.1001/jamanetworkopen.2023.0666
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GENETICS AND GENOMICS

Analysis of Pregnancy Complications and Epigenetic Gestational Age of Newborns

This cohort study evaluates whether exposure to each of 3 pregnancy complications (gestational diabetes, gestational hypertension, and preeclampsia) is associated with accelerated or decelerated gestational biological age in children at birth.

JAMA Netw Open. 2023;6(2):e230672. doi:10.1001/jamanetworkopen.2023.0672
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PEDIATRICS

Assessment of Alcohol Exposure From Alcohol-Based Disinfectants Among Premature Infants in Neonatal Incubators in Japan

This quality improvement study examines blood alcohol concentrations in premature infants and evaporated alcohol concentrations within neonatal incubators before and after implementation of a practice limiting exposure of the infants to alcohol disinfectants.

JAMA Netw Open. 2023;6(2):e230691. doi:10.1001/jamanetworkopen.2023.0691
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ONCOLOGY

Outcomes of Chemoimmunotherapy Among Patients With Extensive-Stage Small Cell Lung Cancer According to Potential Clinical Trial Eligibility

This cohort study compares the outcomes of patients with extensive-stage small cell lung cancer who were included in clinical trials with outcomes of patients who were ineligible for those trials.

JAMA Netw Open. 2023;6(2):e230698. doi:10.1001/jamanetworkopen.2023.0698
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HEALTH POLICY

Cost-effectiveness of Intensive vs Standard Blood Pressure Control Among Older Patients With Hypertension

This economic evaluation estimates the lifetime direct medical costs and quality-adjusted life-years of intensive and standard systolic blood pressure treatments among the older population with hypertension in China, the UK, and the US to examine their cost-effectiveness.

JAMA Netw Open. 2023;6(2):e230708. doi:10.1001/jamanetworkopen.2023.0708
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OBSTETRICS AND GYNECOLOGY

Association of Central Sensitization Inventory Scores With Pain Outcomes After Endometriosis Surgery

This cohort study explores the association between Central Sensitization Inventory scores and persistent pain after endometriosis surgery.

JAMA Netw Open. 2023;6(2):e230780. doi:10.1001/jamanetworkopen.2023.0780
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ONCOLOGY

Evaluation of Lung Cancer Risk Among Persons Undergoing Screening or Guideline-Concordant Monitoring of Lung Nodules in the Mississippi Delta

This cohort study compares the cumulative incidence of lung cancer in screening-age populations within a lung nodule monitoring program and a lung cancer screening program in the Mississippi Delta.

JAMA Netw Open. 2023;6(2):e230787. doi:10.1001/jamanetworkopen.2023.0787
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SURGERY

Association of Variation in US County-Level Rates of Liver Surgical Resection for Colorectal Liver Metastasis With Poverty Rates in 2010

This cross-sectional study uses Surveillance, Epidemiology, and End Results Research Plus data to examine the association of US county-level variation in receipt of liver metastasectomy for colorectal liver metastasis with poverty rates in 2010.

JAMA Netw Open. 2023;6(2):e230797. doi:10.1001/jamanetworkopen.2023.0797
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EQUITY, DIVERSITY, AND INCLUSION

Assessment of US Federal Funding of Incarceration-Related Research, 1985 to 2022

This cross-sectional study compares the number of incarceration-related projects funded at the National Institutes of Health, US Department of Justice, and National Science Foundation compared with other social and behavioral risk–related projects.

JAMA Netw Open. 2023;6(2):e230803. doi:10.1001/jamanetworkopen.2023.0803
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HEALTH POLICY

Association of the End-Stage Renal Disease Treatment Choices Payment Model With Home Dialysis Use at Kidney Failure Onset From 2016 to 2022

This cohort study examines changes in the use of home dialysis among patients with kidney failure after implementation of the End-Stage Renal Disease Treatment Choices payment model.

JAMA Netw Open. 2023;6(2):e230806. doi:10.1001/jamanetworkopen.2023.0806
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HEALTH INFORMATICS

Predicting the Survival of Patients With Cancer From Their Initial Oncology Consultation Document Using Natural Language Processing

This prognostic study develops and evaluates neural natural language processing models that predict the survival of patients with general cancer using their initial oncologist consultation.

JAMA Netw Open. 2023;6(2):e230813. doi:10.1001/jamanetworkopen.2023.0813
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SURGERY

Effect of a Combined Drug Approach on the Severity of Ischemia-Reperfusion Injury During Liver Transplant: A Randomized Clinical Trial

This randomized clinical trial investigates the effect of a combined drug approach targeting the preimplantation liver graft and recipient on the severity of ischemia-reperfusion injury during transplant.

JAMA Netw Open. 2023;6(2):e230819. doi:10.1001/jamanetworkopen.2023.0819
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NUTRITION, OBESITY, AND EXERCISE

Analysis of Cardiorespiratory Fitness in Early Adulthood and Midlife With All-Cause Mortality and Fatal or Nonfatal Cardiovascular Disease

This cohort study evaluates whether cardiovascular fitness during the early periods of life is associated with morbidity and mortality outcomes and whether the outcomes vary by sex and race.

JAMA Netw Open. 2023;6(2):e230842. doi:10.1001/jamanetworkopen.2023.0842
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UROLOGY

Comparison of Sequential Intravesical Gemcitabine and Docetaxel vs Bacillus Calmette-Guérin for the Treatment of Patients With High-Risk Non–Muscle-Invasive Bladder Cancer

This cohort study compares outcomes of treatment with sequential intravesical gemcitabine and docetaxel vs bacillus Calmette-Guérin among patients with high-risk non–muscle-invasive bladder cancer.

JAMA Netw Open. 2023;6(2):e230849. doi:10.1001/jamanetworkopen.2023.0849
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EQUITY, DIVERSITY, AND INCLUSION

Gender, Racial, and Ethnic Inequities in Receipt of Multiple National Institutes of Health Research Project Grants

This cross-sectional study of National Institutes of Health (NIH) grants examines trends in gender, racial, and ethnic diversity among principal investigators, with a particular focus on investigators holding 3 or more research project grants.

JAMA Netw Open. 2023;6(2):e230855. doi:10.1001/jamanetworkopen.2023.0855
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CARDIOLOGY

Clinicians’ and Patients’ Perspectives on Hypertension Care in a Racially and Ethnically Diverse Population in Primary Care

This qualitative study of 15 patients and 15 clinicians examinged the barriers and facilitators to hypertension control within a racially and ethnically diverse health care system.

JAMA Netw Open. 2023;6(2):e230977. doi:10.1001/jamanetworkopen.2023.0977
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INFECTIOUS DISEASES

Portable Breath-Based Volatile Organic Compound Monitoring for the Detection of COVID-19 During the Circulation of the SARS-CoV-2 Delta Variant and the Transition to the SARS-CoV-2 Omicron Variant

This diagnostic study evaluates the accuracies of breath analysis on detecting patients with COVID-19 in periods when the Delta and Omicron variants were most prevalent.

JAMA Netw Open. 2023;6(2):e230982. doi:10.1001/jamanetworkopen.2023.0982
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PEDIATRICS

Dental Caries in Medicaid-Insured Preschool Children With or Without Special Health Care Needs in Northeast Ohio

This cross-sectional study uses data from Pediatric Providers Against Cavities in Children’s Teeth study to investigate caries experience, including untreated decay, among Medicaid-enrolled preschoolers with or without special health care needs.

JAMA Netw Open. 2023;6(2):e230999. doi:10.1001/jamanetworkopen.2023.0999
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CARDIOLOGY

Assessment of Sex Disparities in Nonacceptance of Statin Therapy and Low-Density Lipoprotein Cholesterol Levels Among Patients at High Cardiovascular Risk

This cohort study assesses sex disparities in nonacceptance of statin therapy and assess their association with low-density lipoprotein (LDL) cholesterol control.

JAMA Netw Open. 2023;6(2):e231047. doi:10.1001/jamanetworkopen.2023.1047
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PUBLIC HEALTH

Rural-Urban Variation in the Association of Adolescent Violence and Handgun Carrying in the United States, 2002-2019

This cross-sectional study examines differences in associations of adolescent interpersonal violence with handgun carrying across the rural-urban continuum.

JAMA Netw Open. 2023;6(2):e231153. doi:10.1001/jamanetworkopen.2023.1153
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INFECTIOUS DISEASES

Acute and Postacute COVID-19 Outcomes Among Immunologically Naive Adults During Delta vs Omicron Waves

This cohort study examines acute and postacute clinical outcomes of SARS-CoV-2 infection during the Delta and Omicron waves among previously immunologically naive adults.

JAMA Netw Open. 2023;6(2):e231181. doi:10.1001/jamanetworkopen.2023.1181
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open access Special Communication

STATISTICS AND RESEARCH METHODS

Introducing the Library of Guidance for Health Scientists (LIGHTS): A Living Database for Methods Guidance

This Special Communication introduces the Library of Guidance for Health Researchers (LIGHTS), a new searchable database for methods guidance for health research involving humans and human populations.

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JAMA Netw Open. 2023;6(2):e2253198. doi:10.1001/jamanetworkopen.2022.53198
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open access Consensus Statement

SURGERY

Development of an Enhanced Recovery After Surgery Surgical Safety Checklist Through a Modified Delphi Process

This consensus statement uses expert-derived consensus using a modified Delphi process to identify enhanced recovery after surgery topics that could be appropriately addressed within the context of a modified surgical safety checklist.

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JAMA Netw Open. 2023;6(2):e2248460. doi:10.1001/jamanetworkopen.2022.48460
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open access Invited Commentary

SURGERY

Equitable Policies and Center-Level Commitment May Be Associated With Improved Access to Kidney Transplantation for Undocumented Immigrants

JAMA Netw Open. 2023;6(2):e2254666. doi:10.1001/jamanetworkopen.2022.54666
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CARDIOLOGY

Heart Failure in Patients With Cancer Treated With Anthracyclines—Revisiting the Foundation of Cardio-Oncology

JAMA Netw Open. 2023;6(2):e2254677. doi:10.1001/jamanetworkopen.2022.54677
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GERIATRICS

New Evidence of the Continuing Need to Improve Nursing Facility Care for Patients With Dementia

JAMA Netw Open. 2023;6(2):e2255141. doi:10.1001/jamanetworkopen.2022.55141
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PUBLIC HEALTH

Opening the Windows for More Effective and Equitable Cancer Screening

JAMA Netw Open. 2023;6(2):e2255596. doi:10.1001/jamanetworkopen.2022.55596
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OBSTETRICS AND GYNECOLOGY

Genitourinary Syndrome of Menopause and the False Promise of Vaginal Laser Therapy

JAMA Netw Open. 2023;6(2):e2255706. doi:10.1001/jamanetworkopen.2022.55706
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CARDIOLOGY

Rivaroxaban for Patients With Acute Coronary Syndromes—Where Do We Stand?

JAMA Netw Open. 2023;6(2):e2255724. doi:10.1001/jamanetworkopen.2022.55724
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CRITICAL CARE MEDICINE

Critical Care and the Postintensive Care Syndrome

JAMA Netw Open. 2023;6(2):e230391. doi:10.1001/jamanetworkopen.2023.0391
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STATISTICS AND RESEARCH METHODS

Transfusion Strategies and the Pragmatic Appeal of Bayesian Analysis for Trauma Research

JAMA Netw Open. 2023;6(2):e230426. doi:10.1001/jamanetworkopen.2023.0426
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ONCOLOGY

Predicting Risk of Cardiotoxic Effects in Breast Cancer: Are We There Yet?

JAMA Netw Open. 2023;6(2):e230577. doi:10.1001/jamanetworkopen.2023.0577
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EQUITY, DIVERSITY, AND INCLUSION

Understanding and Addressing How Racism Can Affect Medical School Admissions—Making the Invisible Visible

JAMA Netw Open. 2023;6(2):e232291. doi:10.1001/jamanetworkopen.2023.2291
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NUTRITION, OBESITY, AND EXERCISE

Importance of Optimizing Cardiorespiratory Fitness in Early Adulthood and Through Midlife

JAMA Netw Open. 2023;6(2):e233637. doi:10.1001/jamanetworkopen.2023.3637
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open access Research Letter

PUBLIC HEALTH

Association of Flavor Perception With Blue vs Purple Cigar Packaging Among US Adults

This survey study examines the association of cigar flavor perception with blue vs purple packaging among US adults.

JAMA Netw Open. 2023;6(2):e2254003. doi:10.1001/jamanetworkopen.2022.54003
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OBSTETRICS AND GYNECOLOGY

Changes in Pregnancy-Associated Deaths in the US During the COVID-19 Pandemic in 2020

This cross-sectional study assesses changes in pregnancy-associated mortality from drug overdose, homicide, suicide, and other causes in the US from 2018 through 2020.

JAMA Netw Open. 2023;6(2):e2254287. doi:10.1001/jamanetworkopen.2022.54287
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ALLERGY

Incidence of Chronic Spontaneous Urticaria Following Receipt of the COVID-19 Vaccine Booster in Switzerland

This cohort study examines the association of the COVID-19 vaccine booster with chronic spontaneous urticaria in Swiss patients.

JAMA Netw Open. 2023;6(2):e2254298. doi:10.1001/jamanetworkopen.2022.54298
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HEALTH POLICY

Association of the Chantix Recall With US Prescribing of Varenicline and Other Medications for Nicotine Dependence

This cross-sectional study evaluates the association between the 2021 varenicline tartrate recall and prescribing of varenicline and other medications for nicotine dependence in a large US national patient cohort.

JAMA Netw Open. 2023;6(2):e2254655. doi:10.1001/jamanetworkopen.2022.54655
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HEALTH POLICY

Dispensing of Ivermectin From Veterans Administration Pharmacies During the COVID-19 Pandemic

This cohort study compares changes in ivermectin dispensing during the COVID-19 pandemic between the Veterans Administration (VA) and retail pharmacy settings and examines the association of the VA national formulary restriction with ivermectin dispensing.

JAMA Netw Open. 2023;6(2):e2254859. doi:10.1001/jamanetworkopen.2022.54859
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PSYCHIATRY

Analysis of Psychiatric Disorders by Age Among Children Following a Mass Terrorist Attack in Nice, France, on Bastille Day, 2016

This cross-sectional study examines psychiatric disorders among children after a mass terrorist attack in Nice, France, in 2016.

JAMA Netw Open. 2023;6(2):e2255472. doi:10.1001/jamanetworkopen.2022.55472
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PUBLIC HEALTH

Analysis of Silver Alert Reporting System Activations for Missing Adults With Dementia in Texas, 2017 to 2022

This cross-sectional study analyzes data from Silver Alert activations in Texas from 2017 to 2022 to identify temporal, geographic, and wandering characteristics of missing adults with dementia.

JAMA Netw Open. 2023;6(2):e2255830. doi:10.1001/jamanetworkopen.2022.55830
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CARDIOLOGY

Prevalence and Incidence of Atrial Fibrillation Among Older Primary Care Patients

This cohort study is a secondary analysis of the VITAL-AF trial and assesses the prevalence and incidence of atrial fibrillation among the trial’s control participants.

JAMA Netw Open. 2023;6(2):e2255838. doi:10.1001/jamanetworkopen.2022.55838
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HEALTH POLICY

Evaluation of Prices for Surgical Procedures Within and Outside Hospital Networks in the US

This economic evaluation examines variations in prices for surgical procedures under the Hospital Price Transparency Rule at hospitals within and outside hospital networks in the US.

JAMA Netw Open. 2023;6(2):e2255849. doi:10.1001/jamanetworkopen.2022.55849
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INFECTIOUS DISEASES

Association of COVID-19 Vaccination With Risk for Incident Diabetes After COVID-19 Infection

This cohort study compares the risk of new-onset hypertension, hyperlipidemia, and diabetes before and after COVID-19 infection among patients who were vaccinated vs unvaccinated before infection.

JAMA Netw Open. 2023;6(2):e2255965. doi:10.1001/jamanetworkopen.2022.55965
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ONCOLOGY

Evaluation of the Incidence of Human Papillomavirus–Associated Squamous Cell Carcinoma of the Sinonasal Tract Among US Adults

This case series assesses the incidence of human papillomavirus (HPV)-associated sinonasal squamous cell carcinoma (SNSCC) and the prevalence of HPV-positive SNSCC among US adults.

JAMA Netw Open. 2023;6(2):e2255971. doi:10.1001/jamanetworkopen.2022.55971
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NEUROLOGY

Benzodiazepine Receptor Agonists Prescribing for Insomnia Among Adults in Primary Health Care Facilities in Beijing, China

This cross-sectional study examines the benzodiazepine receptor agonists (BZRA) prescribing rate for insomnia among adult patients in primary health care facilities (PHFs) in China.

JAMA Netw Open. 2023;6(2):e230044. doi:10.1001/jamanetworkopen.2023.0044
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ONCOLOGY

Navigating the Expanded Access Pathway to Investigational Drugs as an Academic Oncologist

This qualitative study explores academic oncologists’ needs and satisfaction with expanded patient access to investigational drugs.

JAMA Netw Open. 2023;6(2):e230060. doi:10.1001/jamanetworkopen.2023.0060
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PUBLIC HEALTH

Accessibility of State and Territory Public Health Department Website Information on COVID-19 Outpatient Treatments in the US

This cross-sectional study assesses the reading level and accessibility of information on COVID-19 treatments posted on US public health websites for states, territories, and Washington, DC.

JAMA Netw Open. 2023;6(2):e230186. doi:10.1001/jamanetworkopen.2023.0186
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PUBLIC HEALTH

Rates of Spontaneous Abortion in Israel Before and During the COVID-19 Pandemic

This cross-sectional study uses electronic health record data to compare monthly incidence rates of spontaneous abortion in Israel before and during the COVID-19 pandemic.

JAMA Netw Open. 2023;6(2):e230233. doi:10.1001/jamanetworkopen.2023.0233
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PSYCHIATRY

Characterization of Mental Health in US Veterans Before, During, and 2 Years After the Onset of the COVID-19 Pandemic

This cohort study of US veterans reports changes in rates of anxiety and depressive disorders following the COVID-19 pandemic.

JAMA Netw Open. 2023;6(2):e230463. doi:10.1001/jamanetworkopen.2023.0463
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open access Correction

Incomplete Sentence in Discussion Section

JAMA Netw Open. 2023;6(2):e230341. doi:10.1001/jamanetworkopen.2023.0341
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Error in Figure 2B

JAMA Netw Open. 2023;6(2):e230734. doi:10.1001/jamanetworkopen.2023.0734
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Errors in Figure

JAMA Netw Open. 2023;6(2):e231218. doi:10.1001/jamanetworkopen.2023.1218
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Errors in Figure 2

JAMA Netw Open. 2023;6(2):e231256. doi:10.1001/jamanetworkopen.2023.1256
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Error in Figure 1B

JAMA Netw Open. 2023;6(2):e231365. doi:10.1001/jamanetworkopen.2023.1365
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Errors in Methods Section and Supplement

JAMA Netw Open. 2023;6(2):e231692. doi:10.1001/jamanetworkopen.2023.1692
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Errors in Figure 1

JAMA Netw Open. 2023;6(2):e232158. doi:10.1001/jamanetworkopen.2023.2158
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Errors in the Byline and Figure

JAMA Netw Open. 2023;6(2):e232452. doi:10.1001/jamanetworkopen.2023.2452
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Error in Table, Abstract, and Results

JAMA Netw Open. 2023;6(2):e233305. doi:10.1001/jamanetworkopen.2023.3305
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Errors in Figure 3 and Supplement 1

JAMA Netw Open. 2023;6(2):e233459. doi:10.1001/jamanetworkopen.2023.3459
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Error in Visual Abstract

JAMA Netw Open. 2023;6(2):e234174. doi:10.1001/jamanetworkopen.2023.4174
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JAMA Netw Open. 2023;6(2):e230249. doi:10.1001/jamanetworkopen.2023.0249
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