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October 2024 - May 2018

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November 2023, Vol 6, No. 11

open access Original Investigation

NUTRITION, OBESITY, AND EXERCISE

Adapted Mindfulness Training for Interoception and Adherence to the DASH Diet: A Phase 2 Randomized Clinical Trial

This randomized clinical trial assesses the effects of a Mindfulness-Based Blood Pressure Reduction program on interoceptive awareness and adherence to the DASH (Dietary Approaches to Stop Hypertension) diet among adults with elevated unattended office blood pressure.

JAMA Netw Open. 2023;6(11):e2339243. doi:10.1001/jamanetworkopen.2023.39243
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Polygenic Risk Score, Environmental Tobacco Smoke, and Risk of Lung Adenocarcinoma in Never-Smoking Women in Taiwan

This case-control study estimates the risk of lung adenocarcinoma among never-smoking women in Taiwan using data on environmental tobacco smoke and a polygenic risk score.

JAMA Netw Open. 2023;6(11):e2339254. doi:10.1001/jamanetworkopen.2023.39254
Abstract Full Text pdf link PDF

PSYCHIATRY

Adverse Life Experiences and Brain Function: A Meta-Analysis of Functional Magnetic Resonance Imaging Findings

This meta-analysis investigates the association of adverse life experiences and altered brain reactivity measured with functional magnetic resonance imaging (MRI).

JAMA Netw Open. 2023;6(11):e2340018. doi:10.1001/jamanetworkopen.2023.40018
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Family-Centered Prevention to Reduce Discrimination-Related Depressive Symptoms Among Black Adolescents: Secondary Analysis of a Randomized Clinical Trial

This secondary analysis of a randomized clinical trial investigates whether participation in the Strong African American Families program moderates Black adolescents’ depressive symptoms associated with experience of racial discrimination.

JAMA Netw Open. 2023;6(11):e2340567. doi:10.1001/jamanetworkopen.2023.40567
Abstract Full Text pdf link PDF

PEDIATRICS

Extrauterine Placental Perfusion and Oxygenation in Infants With Very Low Birth Weight: A Randomized Clinical Trial

This randomized clinical trial investigates the effect of extrauterine placental perfusion compared with delayed cord clamping on mean hematocrit levels in infants with very low birth weight.

JAMA Netw Open. 2023;6(11):e2340597. doi:10.1001/jamanetworkopen.2023.40597
Abstract Full Text pdf link PDF

PEDIATRICS

Streptococcus salivarius Probiotics to Prevent Acute Otitis Media in Children: A Randomized Clinical Trial

This randomized clinical trial investigates the clinical effectiveness of commercially available Streptococcus salivarius K12 oral probiotic products in the primary prevention of acute otitis media in children attending day care.

JAMA Netw Open. 2023;6(11):e2340608. doi:10.1001/jamanetworkopen.2023.40608
Abstract Full Text pdf link PDF

ONCOLOGY

Incidence of Lung Adenocarcinoma by Age, Sex, and Smoking Status in Taiwan

This cohort study compares incidence rates of lung adenocarcinoma between men and women in Taiwan by smoking status, age, and disease stage.

JAMA Netw Open. 2023;6(11):e2340704. doi:10.1001/jamanetworkopen.2023.40704
Abstract Full Text pdf link PDF

ONCOLOGY

Mortality Risk for Docetaxel-Treated, High-Grade Prostate Cancer With Low PSA Levels: A Meta-Analysis

This meta-analysis evaluates whether adding docetaxel to testosterone suppression plus curative local treatment was associated with decreased mortality among patients with high-grade, localized or locally advanced, nonmetastatic prostate cancer with low serum levels of prostate-specific antigen (PSA).

JAMA Netw Open. 2023;6(11):e2340787. doi:10.1001/jamanetworkopen.2023.40787
Abstract Full Text pdf link PDF

PUBLIC HEALTH

E-Cigarette Use Among US Adults in the 2021 Behavioral Risk Factor Surveillance System Survey

This cross-sectional study uses data from the 2021 Behavioral Risk Factor Surveillance System survey to assess recent patterns in current and daily e-cigarette use among US adults.

JAMA Netw Open. 2023;6(11):e2340859. doi:10.1001/jamanetworkopen.2023.40859
Abstract Full Text pdf link PDF

OPHTHALMOLOGY

Cost-Effectiveness Analysis of Myopia Progression Interventions in Children

This economic evaluation study uses a Markov model to assess the cost-effectiveness of the current myopia progression interventions in a hypothetical cohort of children aged 10 years.

JAMA Netw Open. 2023;6(11):e2340986. doi:10.1001/jamanetworkopen.2023.40986
Abstract Full Text pdf link PDF

PEDIATRICS

Use of Dexmedetomidine and Opioids in Hospitalized Preterm Infants

This cohort study examines the use of dexmedetomidine compared with opioids in premature infants from 2010 to 2020 throughout the US.

JAMA Netw Open. 2023;6(11):e2341033. doi:10.1001/jamanetworkopen.2023.41033
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Electronic Nicotine Delivery Systems and E-Liquid Modifications to Vape Cannabis Depicted in Online Videos

This qualitative study assesses the content of YouTube videos showing use and modifications of electronic nicotine delivery systems to vape cannabis.

JAMA Netw Open. 2023;6(11):e2341075. doi:10.1001/jamanetworkopen.2023.41075
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Racial Disparities in Candidates for Hepatocellular Carcinoma Liver Transplant After 6-Month Wait Policy Change

This cohort study evaluates racial disparities among candidates for hepatocellular carcinoma liver transplant following a 6-month wait policy change.

JAMA Netw Open. 2023;6(11):e2341096. doi:10.1001/jamanetworkopen.2023.41096
Abstract Full Text pdf link PDF

ONCOLOGY

Antitumor Activity and Safety of Dostarlimab Monotherapy in Patients With Mismatch Repair Deficient Solid Tumors: A Nonrandomized Controlled Trial

This nonrandomized controlled trial assesses the antitumor activity and safety of dostarlimab in patients with advanced or recurrent mismatch repair deficiency (dMMR) solid tumors.

JAMA Netw Open. 2023;6(11):e2341165. doi:10.1001/jamanetworkopen.2023.41165
Abstract Full Text pdf link PDF

CARDIOLOGY

Cost of Pacing in Pediatric Patients With Postoperative Heart Block After Congenital Heart Surgery

This economic evaluation study assesses the trends in permanent pacemaker implantation after pediatric congenital heart surgery and estimates the 20-year financial burden to patients and their families.

JAMA Netw Open. 2023;6(11):e2341174. doi:10.1001/jamanetworkopen.2023.41174
Abstract Full Text pdf link PDF

SURGERY

Perceptions of Use of Names, Recognition of Roles, and Teamwork After Labeling Surgical Caps

This quality improvement study assesses frequency of name use and role recognition among perioperative teams before and after the use of caps labeled with individuals' names and roles.

JAMA Netw Open. 2023;6(11):e2341182. doi:10.1001/jamanetworkopen.2023.41182
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Speed and Nighttime Usage Restrictions and the Incidence of Shared Electric Scooter Injuries

This cohort study evaluates the association of restrictions on top speed and nighttime usage on the incidence of electric scooter–related injuries.

JAMA Netw Open. 2023;6(11):e2341194. doi:10.1001/jamanetworkopen.2023.41194
Abstract Full Text pdf link PDF

PSYCHIATRY

Posttraumatic Stress Disorder Symptoms and Cardiovascular and Brain Health in Women

This cross-sectional study assesses associations of posttraumatic stress disorder (PTSD) symptoms with carotid intima media thickness and white matter hyperintensity volume among midlife women and by APOEε4 status.

JAMA Netw Open. 2023;6(11):e2341388. doi:10.1001/jamanetworkopen.2023.41388
Abstract Full Text pdf link PDF

ONCOLOGY

Analysis of the Breast Cancer Journey in Namibia

This cohort study describes the breast cancer journey of Namibian women by race using the World Health Organization Global Breast Cancer Initiative framework.

JAMA Netw Open. 2023;6(11):e2341402. doi:10.1001/jamanetworkopen.2023.41402
Abstract Full Text pdf link PDF

HEALTH POLICY

Cost-Effectiveness of Pharmacist Prescribing for Managing Hypertension in the United States

This economic evaluation estimates the cost-effectiveness of implementing a pharmacist-prescribing intervention to improve blood pressure control in the US.

JAMA Netw Open. 2023;6(11):e2341408. doi:10.1001/jamanetworkopen.2023.41408
Abstract Full Text pdf link PDF

HEALTH POLICY

Changes in the Place of Death of Patients With Cancer After the Introduction of Insurance-Covered, Home-Based Hospice Care in Korea

This cohort study investigates the changes in the place of death of patients with cancer after the introduction of insurance-covered, home-based hospice care services in Korea.

JAMA Netw Open. 2023;6(11):e2341422. doi:10.1001/jamanetworkopen.2023.41422
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Shared Genetic Risk in the Association of Screen Time With Psychiatric Problems in Children

This cohort study evaluates the extent of genetic confounding in the association of screen time with mental health problems among preadolescent children.

JAMA Netw Open. 2023;6(11):e2341502. doi:10.1001/jamanetworkopen.2023.41502
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Time to Endoscopy or Colonoscopy Among Adults Younger Than 50 Years With Iron-Deficiency Anemia and/or Hematochezia in the VHA

This cohort study evaluates the rate of diagnostic endoscopy or colonoscopy and the time to testing among veterans younger than 50 years with iron-deficiency anemia (IDA) and hematochezia.

JAMA Netw Open. 2023;6(11):e2341516. doi:10.1001/jamanetworkopen.2023.41516
Abstract Full Text pdf link PDF

ONCOLOGY

Guideline-Based Follow-Up Outcomes in Patients With Gastrointestinal Stromal Tumor With Low Risk of Recurrence: A Report From the Italian Sarcoma Group

This cohort study examines the outcomes observed after guideline-based 5- and 10-year follow-up in patients with gastrointestinal stromal tumor at low risk of recurrence following surgery.

JAMA Netw Open. 2023;6(11):e2341522. doi:10.1001/jamanetworkopen.2023.41522
Abstract Full Text pdf link PDF

PEDIATRICS

Parents’ Views on Autopsy, Organ Donation, and Research Donation After Neonatal Death

This qualitative study evaluates parents’ view on autopsy, organ donation, and research donation after neonatal death.

JAMA Netw Open. 2023;6(11):e2341533. doi:10.1001/jamanetworkopen.2023.41533
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Fairness of Machine Learning Algorithms for Predicting Foregone Preventive Dental Care for Adults

This prognostic study uses machine learning to predict foregone preventive dental care among adults overall and in sociodemographic subgroups and assesses the algorithmic fairness.

JAMA Netw Open. 2023;6(11):e2341625. doi:10.1001/jamanetworkopen.2023.41625
Abstract Full Text pdf link PDF

PEDIATRICS

Differences in Cerebral Tissue Oxygenation in Preterm Neonates Receiving Adult or Cord Blood Red Blood Cell Transfusions

This cohort study assessed whether adult or allogeneic cord blood packed red blood cell (RBC) transfusions were associated with different cerebral tissue oxygenation kinetics of 17 preterm neonates.

JAMA Netw Open. 2023;6(11):e2341643. doi:10.1001/jamanetworkopen.2023.41643
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Neighborhood Deprivation and DNA Methylation and Expression of Cancer Genes in Breast Tumors

This cross-sectional study examines differences in breast tumor DNA methylation among Black and White women with breast cancer living in areas of low and high neighborhood deprivation.

JAMA Netw Open. 2023;6(11):e2341651. doi:10.1001/jamanetworkopen.2023.41651
Abstract Full Text pdf link PDF

HEALTH POLICY

Tiered Physician Network Plans and Patient Choices of Specialist Physicians

This cross-sectional study examines whether tiered physician networks are associated with patient choice of physician when the plans have been in place for 8 to 12 years and whether there are inequities in patient out-of-pocket costs associated with inequities in access to physicians in a lower-copay tier.

JAMA Netw Open. 2023;6(11):e2341836. doi:10.1001/jamanetworkopen.2023.41836
Abstract Full Text pdf link PDF

ANESTHESIOLOGY

Automated Electronic Frailty Index–Identified Frailty Status and Associated Postsurgical Adverse Events

This cohort study evaluates the use of a frailty index to estimate risk of postoperative adverse outcomes in patients 55 years or older who are recovering from noncardiac surgery.

JAMA Netw Open. 2023;6(11):e2341915. doi:10.1001/jamanetworkopen.2023.41915
Abstract Full Text pdf link PDF

CARDIOLOGY

Presentation and Outcomes of Adults With Overdose-Related Out-of-Hospital Cardiac Arrest

This cohort study evaluates survival and outcomes of adult patients with drug overdose–related out-of-hospital cardiac arrest (OHCA) compared with patients with OHCA unrelated to overdose.

JAMA Netw Open. 2023;6(11):e2341921. doi:10.1001/jamanetworkopen.2023.41921
Abstract Full Text pdf link PDF

SURGERY

Early Integrated Palliative Care Within a Surgical Oncology Clinic

This cohort study analyzes early palliative care integration and its association with changes in advance directive designations among patients with cancer who underwent surgery.

JAMA Netw Open. 2023;6(11):e2341928. doi:10.1001/jamanetworkopen.2023.41928
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Nosocomial SARS-CoV-2 Infections and Mortality During Unique COVID-19 Epidemic Waves

This cohort study describes the incidence rate of nosocomial SARS-CoV-2 infections across all hospitals in Region Stockholm, Sweden, during the COVID-19 pandemic and investigates associated 30-day mortality.

JAMA Netw Open. 2023;6(11):e2341936. doi:10.1001/jamanetworkopen.2023.41936
Abstract Full Text pdf link PDF

PUBLIC HEALTH

COVID-19 Hospitalization in Solid Organ Transplant Recipients on Immunosuppressive Therapy

This cohort study assesses whether patient health conditions and immunosuppressive drug use for the prevention of graft rejection are associated with risk of COVID-19–related hospitalization in solid organ transplant recipients.

JAMA Netw Open. 2023;6(11):e2342006. doi:10.1001/jamanetworkopen.2023.42006
Abstract Full Text pdf link PDF

HEALTH POLICY

Ambulatory Intensive Care for Medically Complex Patients at a Health Care Clinic for Individuals Experiencing Homelessness: The SUMMIT Randomized Clinical Trial

This randomized clinical trial examines the effect of a multidisciplinary ambulatory intensive care unit intervention on health care utilization and patient-reported outcomes among medically and socially complex patients experiencing homelessness.

JAMA Netw Open. 2023;6(11):e2342012. doi:10.1001/jamanetworkopen.2023.42012
Abstract Full Text pdf link PDF

ONCOLOGY

Pembrolizumab Plus Chemotherapy Followed by Pembrolizumab in Patients With Early Triple-Negative Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial

This secondary analysis of the KEYNOTE-522 randomized clinical trial evaluates efficacy and safety outcomes of neoadjuvant and adjuvant pembrolizumab for patients enrolled in East and Southeast Asia.

JAMA Netw Open. 2023;6(11):e2342107. doi:10.1001/jamanetworkopen.2023.42107
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Estimated Effectiveness of Coadministration of the BNT162b2 BA.4/5 COVID-19 Vaccine With Influenza Vaccine

This comparative effectiveness study compares the estimated effectiveness of coadministration of the BNT162b2 BA.4/5 bivalent mRNA COVID-19 vaccine and seasonal influenza vaccine vs administration of each vaccine separately in adults.

JAMA Netw Open. 2023;6(11):e2342151. doi:10.1001/jamanetworkopen.2023.42151
Abstract Full Text pdf link PDF

HEMATOLOGY

Adverse Event Reporting in Randomized Clinical Trials for Multiple Myeloma

This cohort study examines the use of minimizing terms in adverse event reporting in multiple myeloma randomized clinical trials published between 2015 and early 2023.

JAMA Netw Open. 2023;6(11):e2342195. doi:10.1001/jamanetworkopen.2023.42195
Abstract Full Text pdf link PDF

GERIATRICS

Algorithmic Fairness of Machine Learning Models for Alzheimer Disease Progression

This prognostic study investigates the algorithmic fairness by sex, race, and ethnicity of machine learning models predicting Alzheimer disease progression.

JAMA Netw Open. 2023;6(11):e2342203. doi:10.1001/jamanetworkopen.2023.42203
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Low-Value Surgical Procedures in Low- and Middle-Income Countries: A Systematic Scoping Review

This systematic review investigates the factors associated with, extent and consequences of, and potential solutions for the overuse of low-value or unnecessary surgical procedures in low- and middle-income countries.

JAMA Netw Open. 2023;6(11):e2342215. doi:10.1001/jamanetworkopen.2023.42215
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Recent Incarceration, Substance Use, Overdose, and Service Use Among People Who Use Drugs in Rural Communities

This cross-sectional study analyzes data from the Rural Opioid Initiative research consortium survey to assess associations between recent incarceration, overdose, and substance use disorder treatment access among rural people who use drugs.

JAMA Netw Open. 2023;6(11):e2342222. doi:10.1001/jamanetworkopen.2023.42222
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Overdose Prevention Centers, Crime, and Disorder in New York City

This cohort study uses administrative data to evaluate the changes in crime and disorder associated with the opening of 2 overdose prevention centers in New York City.

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JAMA Netw Open. 2023;6(11):e2342228. doi:10.1001/jamanetworkopen.2023.42228
Abstract Full Text pdf link PDF

CARDIOLOGY

Frailty, Home Time, and Health Care Costs in Older Adults With Atrial Fibrillation Receiving Oral Anticoagulants

This cohort study of Medicare beneficiaries with arial fibrillation compares home time, health care cost, and clinical events associated with commonly prescribed oral anticoagulants by frailty level.

JAMA Netw Open. 2023;6(11):e2342264. doi:10.1001/jamanetworkopen.2023.42264
Abstract Full Text pdf link PDF

ONCOLOGY

Survival Outcomes in Premenopausal Patients With Invasive Lobular Carcinoma

This cohort study uses data from 2 large national registries and a single-center database to compare long-term survival outcomes in premenopausal patients with invasive lobular carcinoma vs those with invasive ductal carcinoma.

JAMA Netw Open. 2023;6(11):e2342270. doi:10.1001/jamanetworkopen.2023.42270
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Neighborhood Disadvantage, Race and Ethnicity, and Postpartum Depression

This large cross-sectional study of individuals in California evaluates the association between neighborhood disadvantage and postpartum depression and assesses whether any association differs by race and ethnicity among postpartum individuals 15 years or older.

JAMA Netw Open. 2023;6(11):e2342398. doi:10.1001/jamanetworkopen.2023.42398
Abstract Full Text pdf link PDF

HEALTH POLICY

Effect of a Peer Comparison and Educational Intervention on Medical Test Conversation Quality: A Randomized Clinical Trial

This randomized clinical trial evaluates the effects of a peer compairson and education intervention on medical test conversation quality between primary care physicians and patients during annual visits.

JAMA Netw Open. 2023;6(11):e2342464. doi:10.1001/jamanetworkopen.2023.42464
Abstract Full Text pdf link PDF

PEDIATRICS

mRNA SARS-CoV-2 Vaccination Before vs During Pregnancy and Omicron Infection Among Infants

This cohort study investigates the association of maternal vaccination against SARS-CoV-2 Omicron variants before vs during pregnancy with risk of infection among infants.

JAMA Netw Open. 2023;6(11):e2342475. doi:10.1001/jamanetworkopen.2023.42475
Abstract Full Text pdf link PDF

COMPLEMENTARY AND ALTERNATIVE MEDICINE

Acupuncture vs Massage for Pain in Patients Living With Advanced Cancer: The IMPACT Randomized Clinical Trial

This randomized clinical trial compares the effectiveness of acupuncture and massage as treatment for musculoskeletal pain in patients with advanced cancer.

JAMA Netw Open. 2023;6(11):e2342482. doi:10.1001/jamanetworkopen.2023.42482
Abstract Full Text pdf link PDF

ANESTHESIOLOGY

NT-proBNP or Self-Reported Functional Capacity in Estimating Risk of Cardiovascular Events After Noncardiac Surgery

This cohort study surgery compares the addition of N-terminal pro–brain natriuretic peptide measures vs self-reported functional capacity to clinical scores estimating the risk of major adverse cardiovascular events among patients undergoing noncardiac surgery.

JAMA Netw Open. 2023;6(11):e2342527. doi:10.1001/jamanetworkopen.2023.42527
Abstract Full Text pdf link PDF

GLOBAL HEALTH

Economic Growth and Childhood Malnutrition in Low- and Middle-Income Countries

This cross-sectional study investigates the association between per-capita gross domestic product and children’s risk of being malnourished in low- and middle-income countries (LMICs) and evaluates contributing factors that provide the broadest scope for economic growth to reduce malnutrition.

JAMA Netw Open. 2023;6(11):e2342654. doi:10.1001/jamanetworkopen.2023.42654
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Reduction of Financial Health Incentives and Changes in Physical Activity

This case-control study of Canadian users of a phone app focused on physical fitness and health examines the association of partial withdrawal of financial incentives with physical activity.

JAMA Netw Open. 2023;6(11):e2342663. doi:10.1001/jamanetworkopen.2023.42663
Abstract Full Text pdf link PDF

NEUROLOGY

Constricting Life Space and Likelihood of Neurodegenerative Disease in Community-Dwelling Older Men

This cohort study evaluates associations of change in life space, a measure of the frequency, range, and independence of movement through the environment, with cognitive decline or incident neurodegenerative disease over 7 years among community-dwelling older men.

JAMA Netw Open. 2023;6(11):e2342670. doi:10.1001/jamanetworkopen.2023.42670
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Comorbid Prolonged Grief, PTSD, and Depression Trajectories for Bereaved Family Surrogates

This cohort study examines the prevalence and co-occurrence of prolonged grief disorder, posttraumatic stress disorder (PTSD), and depressive symptom trajectories among family surrogates of patients who died in intensive care in Taiwan.

JAMA Netw Open. 2023;6(11):e2342675. doi:10.1001/jamanetworkopen.2023.42675
Abstract Full Text pdf link PDF

ONCOLOGY

Patient Preferences for Lung Cancer Interception Therapy

This survey study explores preferences of individuals at high risk for lung cancer for potential interception therapies to reduce this risk.

JAMA Netw Open. 2023;6(11):e2342681. doi:10.1001/jamanetworkopen.2023.42681
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Age at Diagnosis of Atrial Fibrillation and Incident Dementia

This cohort study examines whether age at diagnosis of atrial fibrillation is associated with risk of incident dementia and its subtypes.

JAMA Netw Open. 2023;6(11):e2342744. doi:10.1001/jamanetworkopen.2023.42744
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

External Validation and Updating of a Statistical Civilian-Based Suicide Risk Model in US Naval Primary Care

This cohort study externally validates and updates a statistical suicide risk model initially developed in a civilian setting with an emphasis on primary care for use among US Navy service members.

JAMA Netw Open. 2023;6(11):e2342750. doi:10.1001/jamanetworkopen.2023.42750
Abstract Full Text pdf link PDF

HEALTH POLICY

Geographic Variation in Qualified Health Plan Coverage and Prior Authorization Requirements for HIV Preexposure Prophylaxis

This cross-sectional study analyzes coverage and prior authorization requirements for HIV preexposure prophylaxis among qualified health plans from 2018 to 2020.

JAMA Netw Open. 2023;6(11):e2342781. doi:10.1001/jamanetworkopen.2023.42781
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Adoption of Emergency Department–Initiated Buprenorphine for Patients With Opioid Use Disorder: Secondary Analysis of a Cluster Randomized Trial

This secondary analysis of a cluster randomized trial examines the factors, including social contagion, associated with the adoption of the practice of emergency department (ED) initiation of buprenorphine for patients with opioid use disorder.

JAMA Netw Open. 2023;6(11):e2342786. doi:10.1001/jamanetworkopen.2023.42786
Abstract Full Text pdf link PDF

ONCOLOGY

Posttreatment Surveillance Imaging After Radiation for Head and Neck Cancer

This comparative effectiveness research study assesses the use of surveillance imaging in asymptomatic patients with head and neck cancer in remission after completion of chemoradiation.

JAMA Netw Open. 2023;6(11):e2342825. doi:10.1001/jamanetworkopen.2023.42825
Abstract Full Text pdf link PDF

CARDIOLOGY

Obesity and Cardiac Conduction Block Disease in China

This cohort study investigates the association of obesity with risk of developing cardiac conduction block and subtypes among patients in China.

JAMA Netw Open. 2023;6(11):e2342831. doi:10.1001/jamanetworkopen.2023.42831
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Ascertainment of Minimal Clinically Important Differences in the Diabetes Distress Scale–17: A Secondary Analysis of a Randomized Clinical Trial

This secondary analysis uses randomized clinical trial data to establish a distribution-based metric for minimal clinically important differences in Diabetes Distress Scale–17 scores and assesses whether changes on these levels are associated with changes in glycated hemoglobin management.

JAMA Netw Open. 2023;6(11):e2342950. doi:10.1001/jamanetworkopen.2023.42950
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Police Violence in Health Care Settings in US Media Coverage

This qualitative study evaluates the harms exerted by health care–affiliated police and security personnel as reported in US media coverage.

JAMA Netw Open. 2023;6(11):e2342998. doi:10.1001/jamanetworkopen.2023.42998
Abstract Full Text pdf link PDF

PSYCHIATRY

Regional Vulnerability Indices in Youth With Persistent and Distressing Psychoticlike Experiences

This cohort study examines the use of cortical and subcortical regional vulnerability indices to estimate the degree to which persistent and distressing psychoticlike experiences in children exhibit neural metrics that show similarity to adults with chronic psychiatric and neurologic conditions.

JAMA Netw Open. 2023;6(11):e2343081. doi:10.1001/jamanetworkopen.2023.43081
Abstract Full Text pdf link PDF

HEALTH POLICY

The Patient Protection and Affordable Care Act and Pediatric Medical Clinicians’ Application of Fluoride Varnish

This cohort study examines whether changes in the rate of application of fluoride varnish in children occurred following mandate of the Patient Protection and Affordable Care Act.

JAMA Netw Open. 2023;6(11):e2343087. doi:10.1001/jamanetworkopen.2023.43087
Abstract Full Text pdf link PDF

ONCOLOGY

Geographic Variation in Late-Stage Cervical Cancer Diagnosis

This cross-sectional study investigates geospatial clusters of late-stage cervical cancer at time of diagnosis in Texas.

JAMA Netw Open. 2023;6(11):e2343152. doi:10.1001/jamanetworkopen.2023.43152
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Perceived Interpersonal Racism and Incident Stroke Among US Black Women

This cohort study examines the association of perceived interpersonal racism with incident stroke among US Black women.

JAMA Netw Open. 2023;6(11):e2343203. doi:10.1001/jamanetworkopen.2023.43203
Abstract Full Text pdf link PDF

PSYCHIATRY

Pathological Networking of Gray Matter Dendritic Density With Classic Brain Morphometries in OCD

This case-control study examines whether dendritic morphology is altered in patients with obsessive-compulsive disorder (OCD) compared with healthy controls and whether such alterations are associated with other brain structural metrics in pathological networks.

JAMA Netw Open. 2023;6(11):e2343208. doi:10.1001/jamanetworkopen.2023.43208
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Progression of Gastrointestinal Injury During Antiplatelet Therapy After Percutaneous Coronary Intervention: A Secondary Analysis of the OPT-PEACE Randomized Clinical Trial

This secondary analysis of a randomized clinical trial assesses the association of aspirin, clopidogrel, and their combination with gastrointestinal injury progression among patients in China without high bleeding risk after percutaneous coronary intervention.

JAMA Netw Open. 2023;6(11):e2343219. doi:10.1001/jamanetworkopen.2023.43219
Abstract Full Text pdf link PDF

ONCOLOGY

Second Primary Lung Cancer Among Lung Cancer Survivors Who Never Smoked

This cohort study characterizes and quantifies second primary lung cancer incidence and disease burden among lung cancer survivors who never vs ever smoked.

JAMA Netw Open. 2023;6(11):e2343278. doi:10.1001/jamanetworkopen.2023.43278
Abstract Full Text pdf link PDF

HEALTH POLICY

National Comprehensive Cancer Network Guideline Recommendations of Cancer Drugs With Accelerated Approval

This cross-sectional study evaluates the basis for the supporting evidence and treatment preference ratings for cancer drugs and indications recommended by the National Comprehensive Cancer Network (NCCN) guidelines committees.

JAMA Netw Open. 2023;6(11):e2343285. doi:10.1001/jamanetworkopen.2023.43285
Abstract Full Text pdf link PDF

NEPHROLOGY

Mendelian Randomization Analysis of Genetic Proxies of Thiazide Diuretics and the Reduction of Kidney Stone Risk

This genetic association study including genome-wide association study summary statistics of US and European adults uses mendelian randomization analysis to examine the association of genetic proxies of thiazide diuretics with the risk of kidney stones.

JAMA Netw Open. 2023;6(11):e2343290. doi:10.1001/jamanetworkopen.2023.43290
Abstract Full Text pdf link PDF

CARDIOLOGY

Cardiovascular Outcomes of α-Blockers vs 5-α Reductase Inhibitors for Benign Prostatic Hyperplasia

This cohort study compares the cardiovascular safety profile of α-blockers vs 5-α reductase inhibitors for patients with benign prostatic hyperplasia.

JAMA Netw Open. 2023;6(11):e2343299. doi:10.1001/jamanetworkopen.2023.43299
Abstract Full Text pdf link PDF

PEDIATRICS

Severe Respiratory Disease Among Children With and Without Medical Complexity During the COVID-19 Pandemic

This cross-sectional study compares respiratory-related hospitalizations, intensive care unit admissions, and mortality during the pandemic vs prepandemic among children with and without medical complexity.

JAMA Netw Open. 2023;6(11):e2343318. doi:10.1001/jamanetworkopen.2023.43318
Abstract Full Text pdf link PDF

PUBLIC HEALTH

Human Papillomavirus Awareness by Educational Level and by Race and Ethnicity

This cross-sectional study assesses the weighted prevalence of human papillomavirus awareness by educational attainment and race and ethnicity among US noninstitutionalized adults.

JAMA Netw Open. 2023;6(11):e2343325. doi:10.1001/jamanetworkopen.2023.43325
Abstract Full Text pdf link PDF

ONCOLOGY

Type 2 Diabetes and Colorectal Cancer Risk

This cohort study evaluates the association of diabetes with colorectal cancer risk in an African American, low-income population.

JAMA Netw Open. 2023;6(11):e2343333. doi:10.1001/jamanetworkopen.2023.43333
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Molecular Diagnostic Yield of Exome Sequencing in Patients With Congenital Hydrocephalus: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis explores whether exome sequencing should be used as a test for the molecular diagnosis of congenital hydrocephalus.

JAMA Netw Open. 2023;6(11):e2343384. doi:10.1001/jamanetworkopen.2023.43384
Abstract Full Text pdf link PDF

GASTROENTEROLOGY AND HEPATOLOGY

Cost-Effectiveness of Liquid Biopsy for Colorectal Cancer Screening in Patients Who Are Unscreened

This economic evaluation estimates the cost-effectiveness of liquid biopsy for colorectal screening in the US.

JAMA Netw Open. 2023;6(11):e2343392. doi:10.1001/jamanetworkopen.2023.43392
Abstract Full Text pdf link PDF

CARDIOLOGY

Mortality in ST-Segment Elevation Myocardial Infarction With Nonobstructive Coronary Arteries and Mimickers

This cohort study evaluates mortality in ST-segment elevation myocardial infarction with nonobstructive coronary arteries.

JAMA Netw Open. 2023;6(11):e2343402. doi:10.1001/jamanetworkopen.2023.43402
Abstract Full Text pdf link PDF

NEUROLOGY

Multimodal Analysis of Secondary Cerebellar Alterations After Pediatric Traumatic Brain Injury

This cohort study analyzes alterations in subregional cerebellum volume and cerebral white matter microstructure and its association with executive function after pediatric traumatic brain injury (TBI).

JAMA Netw Open. 2023;6(11):e2343410. doi:10.1001/jamanetworkopen.2023.43410
Abstract Full Text pdf link PDF

HEALTH POLICY

Completion of Recommended Tests and Referrals in Telehealth vs In-Person Visits

This cohort study examines the rates of completion of referrals for tests among patients with telehealth, in-person, and no visits.

JAMA Netw Open. 2023;6(11):e2343417. doi:10.1001/jamanetworkopen.2023.43417
Abstract Full Text pdf link PDF

STATISTICS AND RESEARCH METHODS

Industry Involvement and Transparency in the Most Cited Clinical Trials, 2019-2022

This cross-sectional study evaluates the modes of industry involvement and the transparency features of the most cited recent clinical trials across medicine.

JAMA Netw Open. 2023;6(11):e2343425. doi:10.1001/jamanetworkopen.2023.43425
Abstract Full Text pdf link PDF

PEDIATRICS

Remote Monitoring for Seizures During Therapeutic Hypothermia in Neonates With Hypoxic-Ischemic Encephalopathy

This cohort study evaluates electroencephalography characteristics in newborns with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia.

JAMA Netw Open. 2023;6(11):e2343429. doi:10.1001/jamanetworkopen.2023.43429
Abstract Full Text pdf link PDF

ONCOLOGY

Patient-Reported Outcomes, Tumor Markers, and Survival Outcomes in Advanced GI Cancer

This cohort study examines the association of 1-month changes in patient-reported outcomes and serum tumor markers with treatment response and survival among patients with gastrointestinal cancer.

JAMA Netw Open. 2023;6(11):e2343512. doi:10.1001/jamanetworkopen.2023.43512
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Brain Volume in Fetal Alcohol Spectrum Disorders Over a 20-Year Span

This cohort studies uses magnetic resonance images taken 20 years apart to assess whether brain tissue declines faster with aging in individuals with fetal alcohol spectrum disorders compared with unexposed controls.

JAMA Netw Open. 2023;6(11):e2343618. doi:10.1001/jamanetworkopen.2023.43618
Abstract Full Text pdf link PDF

ONCOLOGY

Leveraging Large Language Models for Decision Support in Personalized Oncology

This diagnostic study evaluates treatment recommendations for 10 fictional patients with advanced cancer made by 4 large language models, as evaluated by members of a molecular tumor board.

JAMA Netw Open. 2023;6(11):e2343689. doi:10.1001/jamanetworkopen.2023.43689
Abstract Full Text pdf link PDF

HEALTH POLICY

Ranking Decision-Making Criteria for Early Adoption of Innovative Surgical Technologies

This decision analytical modeling study investigates the weighting of criteria used by surgeons, surgical administrators, and health technology assessment experts to make decisions concerning the early adoption of innovative surgical technologies.

JAMA Netw Open. 2023;6(11):e2343703. doi:10.1001/jamanetworkopen.2023.43703
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Prevalence of Perinatal Anxiety and Related Disorders in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis examines the prevalence of anxiety and related disorders among perinatal women living in low- and middle-income countries.

JAMA Netw Open. 2023;6(11):e2343711. doi:10.1001/jamanetworkopen.2023.43711
Abstract Full Text pdf link PDF

PEDIATRICS

Educational Outcomes for Children at 7 to 9 Years of Age After Birth at 39 vs 40 to 42 Weeks’ Gestation

This cohort study, using a causal inference framework based on target trial emulation, evaluates the association of birth at 39 weeks’ gestation with childhood numeracy and literacy scores at 7 to 9 years of age compared with birth at 40 to 42 weeks’ gestation.

JAMA Netw Open. 2023;6(11):e2343721. doi:10.1001/jamanetworkopen.2023.43721
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Antenatal Corticosteroid Treatment During the Late-Preterm Period and Neonatal Outcomes for Twin Pregnancies

This cohort study evaluates whether antenatal corticosteroid treatment during the late-preterm period in twin pregnancies is associated with a lower risk of newborn morbidity.

JAMA Netw Open. 2023;6(11):e2343781. doi:10.1001/jamanetworkopen.2023.43781
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Research Priorities for Pediatric Emergency Care to Address Disparities by Race, Ethnicity, and Language

This survey study investigates research priorities among medical personnel, researchers, and community organizations to address disparities in pediatric emergency care.

JAMA Netw Open. 2023;6(11):e2343791. doi:10.1001/jamanetworkopen.2023.43791
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Cancer Screening Disparities Before and After the COVID-19 Pandemic

This cross-sectional study analyzes changes in breast, cervical, and colorectal cancer screening before and after the COVID-19 pandemic among adults in Ontario, Canada.

JAMA Netw Open. 2023;6(11):e2343796. doi:10.1001/jamanetworkopen.2023.43796
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Preeclampsia and Long-Term Risk of Venous Thromboembolism

This cohort study examines the association between preeclampsia and the risk of venous thromboembolism during pregnancy, during the puerperium, and after the puerperium.

JAMA Netw Open. 2023;6(11):e2343804. doi:10.1001/jamanetworkopen.2023.43804
Abstract Full Text pdf link PDF

PEDIATRICS

Cognitive and Emotional Well-Being of Preschool Children Before and During the COVID-19 Pandemic

This cross-sectional study compares cognitive and emotional development scores of preschool-aged Canadian children exposed to the COVID-19 pandemic with scores of children assessed prior to the pandemic.

JAMA Netw Open. 2023;6(11):e2343814. doi:10.1001/jamanetworkopen.2023.43814
Abstract Full Text pdf link PDF

CARDIOLOGY

Plasma Ceramides and Sphingomyelins and Sudden Cardiac Death in the Cardiovascular Health Study

This cohort study addresses whether ceramide and sphingomyelin species containing very-long-chain saturated fatty acids were associated with a reduced risk of sudden cardiac death (SCD) and whether species containing palmitic acid were associated with an increased risk of SCD among participants in the Cardiovascular Health Study.

JAMA Netw Open. 2023;6(11):e2343854. doi:10.1001/jamanetworkopen.2023.43854
Abstract Full Text pdf link PDF

ONCOLOGY

Statin Use, Cholesterol Level, and Mortality Among Females With Breast Cancer

This cohort study evaluates the association of serum cholesterol level and statin use with breast cancer (BC)–specific and overall mortality in females with invasive BC.

JAMA Netw Open. 2023;6(11):e2343861. doi:10.1001/jamanetworkopen.2023.43861
Abstract Full Text pdf link PDF

ONCOLOGY

Chemotherapy-Related Amenorrhea and Quality of Life Among Premenopausal Women With Breast Cancer

This cohort study assesses factors associated with chemotherapy-related amenorrhea and evaluates its association with long-term quality of life among premenopausal women with breast cancer.

JAMA Netw Open. 2023;6(11):e2343910. doi:10.1001/jamanetworkopen.2023.43910
Abstract Full Text pdf link PDF

CARDIOLOGY

Genetic and Environmental Factors and Cardiovascular Disease Risk in Adolescents

This cohort study examines the role of genetic and environmental factors shared by full siblings in the association of cardiovascular risk factors during adolescence with future cardiovascular disease.

JAMA Netw Open. 2023;6(11):e2343947. doi:10.1001/jamanetworkopen.2023.43947
Abstract Full Text pdf link PDF

PEDIATRICS

Infertility and Risk of Autism Spectrum Disorder in Children

This cohort study evaluates the association between infertility and autism spectrum disorder in children in Canada.

JAMA Netw Open. 2023;6(11):e2343954. doi:10.1001/jamanetworkopen.2023.43954
Abstract Full Text pdf link PDF

ONCOLOGY

Deficit Accumulation Index and Biological Markers of Aging in Survivors of Childhood Cancer

This cross-sectional study assesses the use of a deficit accumulation index to measure aging-related conditions, such as epigenetic age and telomere length, in adult survivors of acute lymphoblastic leukemia, Hodgkin lymphoma, or central nervous system tumors.

JAMA Netw Open. 2023;6(11):e2344015. doi:10.1001/jamanetworkopen.2023.44015
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Intake of Energy Drinks Before and During Pregnancy and Adverse Pregnancy Outcomes

This cohort study uses data from the Nurses’ Health Study and the Growing Up Today Study to assess the association of energy drink intake before and during pregnancy with risk of adverse pregnancy outcomes.

JAMA Netw Open. 2023;6(11):e2344023. doi:10.1001/jamanetworkopen.2023.44023
Abstract Full Text pdf link PDF

PULMONARY MEDICINE

Accuracy of Expected Symptoms and Subsequent Quality of Life Measures Among Adults With COPD

This cohort study compares what patients with severe chronic obstructive pulmonary disease expect to experience at diagnosis with reported experiences over a 24-month period.

JAMA Netw Open. 2023;6(11):e2344030. doi:10.1001/jamanetworkopen.2023.44030
Abstract Full Text pdf link PDF

CARDIOLOGY

Social Determinants of Health and Cardiologist Involvement in the Care of Adults Hospitalized for Heart Failure

This cohort study examines whether social determinants of health are associated with cardiologist involvement in the management of adults hospitalized with heart failure (HF).

JAMA Netw Open. 2023;6(11):e2344070. doi:10.1001/jamanetworkopen.2023.44070
Abstract Full Text pdf link PDF

PSYCHIATRY

App-Based Interventions for Moderate to Severe Depression: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis examines the treatment efficacy associated with mobile application (app) interventions for moderate to severe depression and identifies factors associated with better treatment outcomes.

JAMA Netw Open. 2023;6(11):e2344120. doi:10.1001/jamanetworkopen.2023.44120
Abstract Full Text pdf link PDF

OTOLARYNGOLOGY

Survival of Patients With Head and Neck Merkel Cell Cancer: Findings From the Pan-Canadian Merkel Cell Cancer Collaborative

This cohort study evaluates the overall survival of patients in Canada with head and neck Merkel cell carcinoma according to American Joint Committee on Cancer 8th edition staging and treatment modalities.

JAMA Netw Open. 2023;6(11):e2344127. doi:10.1001/jamanetworkopen.2023.44127
Abstract Full Text pdf link PDF

PEDIATRICS

Pancreatic Replacement Therapy for Maladaptive Behaviors in Preschool Children With Autism Spectrum Disorder

This cohort study evaluates the use of pancreatic replacement therapy for maladaptive behaviors in preschool children with autism spectrum disorder.

JAMA Netw Open. 2023;6(11):e2344136. doi:10.1001/jamanetworkopen.2023.44136
Abstract Full Text pdf link PDF

GERIATRICS

Food Insecurity, Memory, and Dementia Among US Adults Aged 50 Years and Older

This cohort study examines cognitive outcomes in older individuals with food insecurity.

JAMA Netw Open. 2023;6(11):e2344186. doi:10.1001/jamanetworkopen.2023.44186
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Plasma Biomarkers of Alzheimer Disease in Women With and Without HIV

This cohort study analyzes whether biomarkers for Alzheimer disease are associated with neuropsychological performance among women with and without HIV.

JAMA Netw Open. 2023;6(11):e2344194. doi:10.1001/jamanetworkopen.2023.44194
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

Economic Evaluation of Blood Pressure Monitoring Techniques in Patients With Hypertension: A Systematic Review

This systematic review examines evidence for the cost-effectiveness of at-home blood pressure (BP) self-monitoring vs monitoring in a clinical setting among patients with hypertension.

JAMA Netw Open. 2023;6(11):e2344372. doi:10.1001/jamanetworkopen.2023.44372
Abstract Full Text pdf link PDF

CRITICAL CARE MEDICINE

Patient Outcomes After Long-Term Acute Care Hospital Closures

This cohort study estimates the association of long-term acute care hospital closures with short-stay hospital care patterns and patient outcomes.

JAMA Netw Open. 2023;6(11):e2344377. doi:10.1001/jamanetworkopen.2023.44377
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Projected Life Expectancy Gains From Improvements in HIV Care in Black and White Men Who Have Sex With Men

This decision analytical model evaluates the projected life expectancy gains from improvements in HIV care in men who have sex with men.

JAMA Netw Open. 2023;6(11):e2344385. doi:10.1001/jamanetworkopen.2023.44385
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Physicians’ Perceptions of Clinical Decision Support to Treat Patients With Heart Failure in the ED

This qualitative study evaluates clinical decision support usability and workflow integration among emergency department (ED) physicians who use it in clinical practice.

JAMA Netw Open. 2023;6(11):e2344393. doi:10.1001/jamanetworkopen.2023.44393
Abstract Full Text pdf link PDF

NEUROLOGY

Concussion Characteristics in the National Hockey League Before and After the Introduction of Rule 48

This cohort study compares the incidence and proportion of concussions among National Hockey League (NHL) players due to a hit to the head before (2006 to 2010) and after (2014 to 2019) the implementation of Rule 48 (Illegal Check to the Head).

JAMA Netw Open. 2023;6(11):e2344399. doi:10.1001/jamanetworkopen.2023.44399
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Unstable Housing and Mortality Among US Veterans Receiving Dialysis

This cohort study identifies characteristics associated with unstable housing among US veterans receiving dialysis and estimates the association between unstable housing and mortality risk.

JAMA Netw Open. 2023;6(11):e2344448. doi:10.1001/jamanetworkopen.2023.44448
Abstract Full Text pdf link PDF

NUTRITION, OBESITY, AND EXERCISE

Cardiometabolic Effects of Omnivorous vs Vegan Diets in Identical Twins: A Randomized Clinical Trial

This randomized clinical trial of identical twin pairs compares the cardiometabolic effects of a healthy vegan diet with a healthy omnivorous diet.

JAMA Netw Open. 2023;6(11):e2344457. doi:10.1001/jamanetworkopen.2023.44457
Abstract Full Text pdf link PDF

PEDIATRICS

Skin-to-Skin Contact at Birth for Very Preterm Infants and Mother-Infant Interaction Quality at 4 Months: A Secondary Analysis of the IPISTOSS Randomized Clinical Trial

This secondary analysis of the IPISTOSS randomized clinical trial examines the effect of immediate skin-to-skin contact at birth for very preterm infants on mother-infant interaction quality at 4 months of corrected infant age.

JAMA Netw Open. 2023;6(11):e2344469. doi:10.1001/jamanetworkopen.2023.44469
Abstract Full Text pdf link PDF

ONCOLOGY

Racial and Ethnic Disparity in Preoperative Chemosensitivity and Survival in Patients With Early-Stage Breast Cancer

This cohort study examines the association of chemosensitivity with survival by race and ethnicity in patients with early-stage breast cancer.

JAMA Netw Open. 2023;6(11):e2344517. doi:10.1001/jamanetworkopen.2023.44517
Abstract Full Text pdf link PDF

SUBSTANCE USE AND ADDICTION

Rapid Access Addiction Medicine Clinics for People With Problematic Opioid Use

This cohort study of people with problematic opioid use examines the effectiveness of rapid access addiction medicine clinics on emergency department visits, hospital admissions, and mortality.

JAMA Netw Open. 2023;6(11):e2344528. doi:10.1001/jamanetworkopen.2023.44528
Abstract Full Text pdf link PDF

CARDIOLOGY

Catheter Ablation With Morphologic Repetitiveness Mapping for Persistent Atrial Fibrillation

This randomized clinical trial assesses whether adding ablation guided by periodicity and similarity mapping to pulmonary vein isolation among patients with persistent arial fibrillation (AF) may increase the chances of maintaining sinus rhythm.

JAMA Netw Open. 2023;6(11):e2344535. doi:10.1001/jamanetworkopen.2023.44535
Abstract Full Text pdf link PDF

HEMATOLOGY

Use of Disease-Modifying Treatments in Patients With Sickle Cell Disease

This cross-sectional study describes patient characteristics associated with use of disease-modifying treatments and evaluates the observed annual patterns of individual and composite use among adults and children with sickle cell disease.

JAMA Netw Open. 2023;6(11):e2344546. doi:10.1001/jamanetworkopen.2023.44546
Abstract Full Text pdf link PDF

HEALTH POLICY

Participation in Conditional Cash Transfer Program During Pregnancy and Birth Weight–Related Outcomes

This cohort study investigates the association of participation in the Bolsa Família cash transfer program with birth weight–related outcomes.

JAMA Netw Open. 2023;6(11):e2344691. doi:10.1001/jamanetworkopen.2023.44691
Abstract Full Text pdf link PDF

HEALTH POLICY

Estimated US Cancer Deaths Prevented With Increased Use of Lung, Colorectal, Breast, and Cervical Cancer Screening

This decision analytical model study estimates the number of cancer deaths that could be prevented with a 10–percentage point increase in the use of US Preventive Services Task Force (USPSTF)-recommended screening.

JAMA Netw Open. 2023;6(11):e2344698. doi:10.1001/jamanetworkopen.2023.44698
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Racial and Ethnic Discrimination and Hypertension by Educational Attainment Among a Cohort of US Women

This case-control study investigates educational attainment as a potential effect modifier of associations between racial and ethnic discrimination and hypertension risk among US women.

JAMA Netw Open. 2023;6(11):e2344707. doi:10.1001/jamanetworkopen.2023.44707
Abstract Full Text pdf link PDF

HEALTH INFORMATICS

System-Level Factors and Time Spent on Electronic Health Records by Primary Care Physicians

This cross-sectional study assesses the time primary care physicians spent on the electronic health record in 31 primary care clinics in 2 academic medical center–based primary care networks in 2021.

JAMA Netw Open. 2023;6(11):e2344713. doi:10.1001/jamanetworkopen.2023.44713
Abstract Full Text pdf link PDF

GENETICS AND GENOMICS

Racial and Ethnic Residential Segregation and Monocyte DNA Methylation Age Acceleration

This cohort study examines associations of residential racial and ethnic segregation and census tract–level poverty with DNA methylation age using 4 DNA methylation clocks.

JAMA Netw Open. 2023;6(11):e2344722. doi:10.1001/jamanetworkopen.2023.44722
Abstract Full Text pdf link PDF

HEALTH POLICY

Transitional Care Interventions From Hospital to Community to Reduce Health Care Use and Improve Patient Outcomes: A Systematic Review and Network Meta-Analysis

This systematic review and network meta-analysis evaluates the comparative effectiveness associated with transitional care interventions with different complexity levels at improving health care utilization and patient outcomes in the transition from hospitals to the community.

JAMA Netw Open. 2023;6(11):e2344825. doi:10.1001/jamanetworkopen.2023.44825
Abstract Full Text pdf link PDF

ONCOLOGY

Factors in Parenting Stress in Young Patients With Breast Cancer and Implications for Children’s Emotional Development: The PSYCHE Study

This cross-sectional study examines the clinical factors in parenting stress in mothers with breast cancer and the association of maternal depression and parenting stress with their children's emotional development.

JAMA Netw Open. 2023;6(11):e2344835. doi:10.1001/jamanetworkopen.2023.44835
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Sociodemographic Variations in Women’s Reports of Discussions With Clinicians About Breast Density

This survey study examines the content of women’s reports of breast density discussions with clinicians as well as variations in these discussions by women’s sociodemographic characteristics.

JAMA Netw Open. 2023;6(11):e2344850. doi:10.1001/jamanetworkopen.2023.44850
Abstract Full Text pdf link PDF

ONCOLOGY

Cost-Effectiveness of Annual Prostate MRI and Potential MRI-Guided Biopsy After Prostate-Specific Antigen Test Results

This economic evaluation compares the cost-effectiveness of integrating annual magnetic resonance imaging and potential magnetic resonance imaging–guided biopsy vs standard biopsy as part of clinical decision-making for men after being screened for prostate cancer.

JAMA Netw Open. 2023;6(11):e2344856. doi:10.1001/jamanetworkopen.2023.44856
Abstract Full Text pdf link PDF

OBSTETRICS AND GYNECOLOGY

Access to Reproductive Health Services Among People With Disabilities

This cross-sectional study examines the logistical, access, cost, privacy, and interpersonal barriers to reproductive health care in females with varying disabilities and levels of functioning.

JAMA Netw Open. 2023;6(11):e2344877. doi:10.1001/jamanetworkopen.2023.44877
Abstract Full Text pdf link PDF

PSYCHIATRY

Age Disparities in Prevalence of Anxiety and Depression Among US Adults During the COVID-19 Pandemic

This cross-sectional study investigates age disparities in anxiety and depression throughout the COVID-19 pandemic.

JAMA Netw Open. 2023;6(11):e2345073. doi:10.1001/jamanetworkopen.2023.45073
Abstract Full Text pdf link PDF

PHARMACY AND CLINICAL PHARMACOLOGY

Low-Dose Methotrexate and Serious Adverse Events Among Older Adults With Chronic Kidney Disease

This cohort study compares the 90-day risk of serious adverse events among adults with chronic kidney disease (CKD) who started low-dose methotrexate vs those who started hydroxychloroquine.

JAMA Netw Open. 2023;6(11):e2345132. doi:10.1001/jamanetworkopen.2023.45132
Abstract Full Text pdf link PDF

COMPLEMENTARY AND ALTERNATIVE MEDICINE

Efficacy and Safety of Auricular Acupuncture for Depression: A Randomized Clinical Trial

This randomized clinical trial analyzes the safety and efficacy of auricular acupuncture as a treatment for depression.

JAMA Netw Open. 2023;6(11):e2345138. doi:10.1001/jamanetworkopen.2023.45138
Abstract Full Text pdf link PDF

NEUROLOGY

Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer Disease

This cross-sectional study evaluates whether glial markers are associated with neuropsychiatric symptoms in individuals across the Alzheimer disease continuum.

JAMA Netw Open. 2023;6(11):e2345175. doi:10.1001/jamanetworkopen.2023.45175
Abstract Full Text pdf link PDF

ONCOLOGY

Sodium Levels and Outcomes in Patients With Metastatic Renal Cell Carcinoma Receiving Nivolumab

This cohort study examines the association of serum sodium levels with clinical outcomes in patients with metastatic renal cell carcinoma (RCC) receiving nivolumab.

JAMA Netw Open. 2023;6(11):e2345185. doi:10.1001/jamanetworkopen.2023.45185
Abstract Full Text pdf link PDF

PEDIATRICS

Patent Ductus Arteriosus and Bronchopulmonary Dysplasia–Associated Pulmonary Hypertension: A Bayesian Meta-Analysis

This bayesian meta-analysis examines the association of patent ductus arteriosus with bronchopulmonary dysplasia–associated pulmonary hypertension in extremely preterm infants.

JAMA Netw Open. 2023;6(11):e2345299. doi:10.1001/jamanetworkopen.2023.45299
Abstract Full Text pdf link PDF

EMERGENCY MEDICINE

Race and Ethnicity and Emergency Department Discharge Against Medical Advice

This cross-sectional study assesses the odds of discharge against medical advice from the emergency department by patient race and ethnicity in the US.

JAMA Netw Open. 2023;6(11):e2345437. doi:10.1001/jamanetworkopen.2023.45437
Abstract Full Text pdf link PDF

EQUITY, DIVERSITY, AND INCLUSION

Patient and Care Team Perspectives on Social Determinants of Health Screening in Primary Care: A Qualitative Study

This qualitative analysis uses patient and care team member feedback to identify barriers and facilitators to social determinants of health screening within primary care to inform future screening.

JAMA Netw Open. 2023;6(11):e2345444. doi:10.1001/jamanetworkopen.2023.45444
Abstract Full Text pdf link PDF

HEALTH POLICY

Breast Cancer Screening Among Females With and Without Schizophrenia

This case-control study examines the association between schizophrenia diagnosis, mammography rate, and physician reimbursement structures in Ontario, Canada.

JAMA Netw Open. 2023;6(11):e2345530. doi:10.1001/jamanetworkopen.2023.45530
Abstract Full Text pdf link PDF

HEALTH POLICY

Emergency Medical Responses at US Immigration and Customs Enforcement Detention Centers in California

This cross-sectional study describes emergency medical services– and US Immigration and Customs Enforcement (ICE)–reported medical emergencies in California detention centers.

JAMA Netw Open. 2023;6(11):e2345540. doi:10.1001/jamanetworkopen.2023.45540
Abstract Full Text pdf link PDF

CARDIOLOGY

Intravascular Imaging in Patients With Complex Coronary Lesions and Chronic Kidney Disease

This cohort study evaluates whether the outcomes of intravascular imaging–guided procedural optimization would be different according to the presence of chronic kidney disease.

JAMA Netw Open. 2023;6(11):e2345554. doi:10.1001/jamanetworkopen.2023.45554
Abstract Full Text pdf link PDF

INFECTIOUS DISEASES

Gray Matter Thickness and Subcortical Nuclear Volume in Men After SARS-CoV-2 Omicron Infection

This cohort study explores clinical symptoms and changes to gray matter thickness and subcortical nuclear volume in the acute and 3-month follow-up phases of SARS-CoV-2 Omicron infection among adult male patients.

JAMA Netw Open. 2023;6(11):e2345626. doi:10.1001/jamanetworkopen.2023.45626
Abstract Full Text pdf link PDF

HEALTH POLICY

Economic Evaluation of Exercise or Cognitive and Social Enrichment Activities for Improved Cognition After Stroke

This economic evaluation is a cost-effectiveness and cost-utility analysis of multicomponent exercise or cognitive and social enrichment activities compared with a balance and tone program using data from a randomized clinical trial.

JAMA Netw Open. 2023;6(11):e2345687. doi:10.1001/jamanetworkopen.2023.45687
Abstract Full Text pdf link PDF

PSYCHIATRY

Psychiatric Comorbidities and Schizophrenia in Youths With Attention-Deficit/Hyperactivity Disorder

This cohort study evaluates the association between psychiatric comorbidities and schizophrenia in children and adolescents with attention-deficit/hyperactivity disorder.

JAMA Netw Open. 2023;6(11):e2345793. doi:10.1001/jamanetworkopen.2023.45793
Abstract Full Text pdf link PDF

ONCOLOGY

KRAS Sequence Variation as Prognostic Marker in Patients With Young- vs Late-Onset Colorectal Cancer

This cross-sectional study investigates the association of KRAS sequence variation with survival among patients with young- vs late-onset colorectal cancer.

JAMA Netw Open. 2023;6(11):e2345801. doi:10.1001/jamanetworkopen.2023.45801
Abstract Full Text pdf link PDF

DIABETES AND ENDOCRINOLOGY

Parental Income Level and Risk of Developing Type 2 Diabetes in Youth

This cohort study examines the association of family income level with the risk of youth-onset type 2 diabetes among children and adolescents in Taiwan.

JAMA Netw Open. 2023;6(11):e2345812. doi:10.1001/jamanetworkopen.2023.45812
Abstract Full Text pdf link PDF

PHARMACY AND CLINICAL PHARMACOLOGY

Aneurysm and Artery Dissection After Oral VEGFR-TKI Use in Adults With Cancer

This cohort study investigates the association of tyrosine kinase inhibitors targeting vascular endothelial growth factor receptors with aneurysm and artery dissection in patients with cancer.

JAMA Netw Open. 2023;6(11):e2345977. doi:10.1001/jamanetworkopen.2023.45977
Abstract Full Text pdf link PDF
open access Special Communication

RHEUMATOLOGY

Control Groups in RCTs Supporting Approval of Drugs for Systemic Rheumatic Diseases, 2012-2022

This study investigates the proportion of pivotal randomized clinical trials supporting newly approved systemic rheumatic disease drugs that used optimal control groups

has active quiz
JAMA Netw Open. 2023;6(11):e2344767. doi:10.1001/jamanetworkopen.2023.44767
Abstract Full Text pdf link PDF CME & MOC
open access Editorial

The Planning Fallacy in Patients With Chronic Lung Disease

JAMA Netw Open. 2023;6(11):e2343988. doi:10.1001/jamanetworkopen.2023.43988
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Is Nosocomial SARS-CoV-2 Still Worth Preventing?

JAMA Netw Open. 2023;6(11):e2344704. doi:10.1001/jamanetworkopen.2023.44704
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open access Invited Commentary

PSYCHIATRY

Meta-Analytic Evidence for Association of Adversity With Brain Function

JAMA Netw Open. 2023;6(11):e2339966. doi:10.1001/jamanetworkopen.2023.39966
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PEDIATRICS

Placental Perfusion Rather Than Placental Transfusion—Key to Umbilical Cord Management at Birth?

JAMA Netw Open. 2023;6(11):e2340490. doi:10.1001/jamanetworkopen.2023.40490
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EQUITY, DIVERSITY, AND INCLUSION

Mitigating the Negative Mental Health Impact of Racism on Black Adolescents—A Preventive Perspective

JAMA Netw Open. 2023;6(11):e2340577. doi:10.1001/jamanetworkopen.2023.40577
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OCCUPATIONAL HEALTH

Sleep and Burnout Among Health Care Professionals—The Role of the Individual

JAMA Netw Open. 2023;6(11):e2341882. doi:10.1001/jamanetworkopen.2023.41882
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SURGERY

Teaming Up With Palliative Care to Improve Perioperative Goals of Care Communication

JAMA Netw Open. 2023;6(11):e2341892. doi:10.1001/jamanetworkopen.2023.41892
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CARDIOLOGY

Anticoagulation in Patients With Atrial Fibrillation Who Are Frail—Toward Better Care

JAMA Netw Open. 2023;6(11):e2342258. doi:10.1001/jamanetworkopen.2023.42258
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HEALTH POLICY

We Need to Talk About Low-Value Care

JAMA Netw Open. 2023;6(11):e2342445. doi:10.1001/jamanetworkopen.2023.42445
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HEALTH POLICY

Commercial Determinants of Access to HIV Preexposure Prophylaxis

JAMA Netw Open. 2023;6(11):e2342759. doi:10.1001/jamanetworkopen.2023.42759
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SUBSTANCE USE AND ADDICTION

Invoking a Medical Axiom for Buprenorphine Initiation—See One, Do One, Teach One

JAMA Netw Open. 2023;6(11):e2342980. doi:10.1001/jamanetworkopen.2023.42980
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GENETICS AND GENOMICS

Implications of Exome Sequencing for Patients With Congenital Hydrocephalus

JAMA Netw Open. 2023;6(11):e2343343. doi:10.1001/jamanetworkopen.2023.43343
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GASTROENTEROLOGY AND HEPATOLOGY

Cost-Effectiveness of Blood-Based Biomarkers for Colorectal Cancer Screening—An Ounce of Prevention Is Worth a Pound of Cure

JAMA Netw Open. 2023;6(11):e2343346. doi:10.1001/jamanetworkopen.2023.43346
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SURGERY

Developing Practical Strategies to Enable Better Teamwork and Communication

JAMA Netw Open. 2023;6(11):e2343474. doi:10.1001/jamanetworkopen.2023.43474
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PEDIATRICS

Candidate Pathways Underlying Exposure to the COVID-19 Pandemic and Early Child Development—Risk and Resilience

JAMA Netw Open. 2023;6(11):e2343770. doi:10.1001/jamanetworkopen.2023.43770
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CARDIOLOGY

Mapping Atrial Fibrillation to Improve Ablation Outcomes

JAMA Netw Open. 2023;6(11):e2344481. doi:10.1001/jamanetworkopen.2023.44481
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EQUITY, DIVERSITY, AND INCLUSION

Hypertension Among Black Women—College-Educated But More at Risk?

JAMA Netw Open. 2023;6(11):e2344681. doi:10.1001/jamanetworkopen.2023.44681
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GENETICS AND GENOMICS

Neighborhood Deprivation Measures and DNA Methylation Clocks—Understanding the Real Needs of Each Person

JAMA Netw Open. 2023;6(11):e2344688. doi:10.1001/jamanetworkopen.2023.44688
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HEALTH POLICY

Research in US Immigration Detention—Transparency Through Policy

JAMA Netw Open. 2023;6(11):e2345495. doi:10.1001/jamanetworkopen.2023.45495
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open access Research Letter

PUBLIC HEALTH

Political Ideology and Trust in Government Health Agencies for Cancer Information

This cross-sectional study assesses the association between political ideology and trust in government health agencies for cancer information.

JAMA Netw Open. 2023;6(11):e2341191. doi:10.1001/jamanetworkopen.2023.41191
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EMERGENCY MEDICINE

Clinical Features vs CT Findings to Estimate Need for Surgery in Small Bowel Obstruction

This comparative effectiveness research compares the ability of clinical features vs clinical features with computed tomography (CT) to estimate the need for small bowel obstruction surgery.

JAMA Netw Open. 2023;6(11):e2341376. doi:10.1001/jamanetworkopen.2023.41376
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SUBSTANCE USE AND ADDICTION

Factors Associated With Abrupt Discontinuation of Long-Term High-Dose Opioid Treatment

This cohort study investigates factors associated with abrupt discontinuation of long-term high-dose opioid treatment at the national level and across US states.

JAMA Netw Open. 2023;6(11):e2341416. doi:10.1001/jamanetworkopen.2023.41416
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HEALTH POLICY

Teleworking, Parenting Stress, and the Health of Mothers and Fathers

This cross-sectional study examines the associations of telework during the COVID-19 pandemic with parents’ general health, changes to mental health, and parenting stress.

JAMA Netw Open. 2023;6(11):e2341844. doi:10.1001/jamanetworkopen.2023.41844
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OCCUPATIONAL HEALTH

Sleep Disturbance and Burnout in Emergency Department Health Care Workers

This cross-sectional study examines the association of sleep disturbances with burnout among emergency medicine health care workers.

JAMA Netw Open. 2023;6(11):e2341910. doi:10.1001/jamanetworkopen.2023.41910
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HEALTH POLICY

False or Misleading Claims in Online Direct-to-Consumer Ketamine Advertising in Maryland

This cross-sectional study evaluates the prevalence of false or misleading information in online direct-to-consumer advertising for off-label and unapproved ketamine in Maryland.

JAMA Netw Open. 2023;6(11):e2342210. doi:10.1001/jamanetworkopen.2023.42210
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INFECTIOUS DISEASES

Self-Reported Neuropsychiatric Post–COVID-19 Condition and CSF Markers of Neuroinflammation

This case-control study assesses cerebrospinal fluid markers of neuroinflammation and blood-brain barrier disruption in individuals with post–COVID-19 condition who reported neuropsychiatric symptoms.

JAMA Netw Open. 2023;6(11):e2342741. doi:10.1001/jamanetworkopen.2023.42741
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PEDIATRICS

School Closures and ED Visits for Suicidality in Youths Before and During the COVID-19 Pandemic

This cohort study investigates the association of COVID-19–related school closures with rates of emergency department suicidality visits among youths ages 12 to 25 years.

JAMA Netw Open. 2023;6(11):e2343001. doi:10.1001/jamanetworkopen.2023.43001
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HEALTH INFORMATICS

Patient Usage of Apps to Access Online Medical Records

This cross-sectional study analyzes the use of patient portal apps and third-party apps for managing multiple patient portals between 2019 and 2022.

JAMA Netw Open. 2023;6(11):e2343312. doi:10.1001/jamanetworkopen.2023.43312
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HEALTH POLICY

Mystery Shopper Study of State Medicaid Coverage for Out-of-State Abortion Care

This cross-sectional study uses a mystery shopper survey to examine variation in state Medicaid agency responses to coverage questions on out-of-state abortion care.

JAMA Netw Open. 2023;6(11):e2343569. doi:10.1001/jamanetworkopen.2023.43569
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HEALTH POLICY

Expiration of State Licensure Waivers and Out-of-State Telemedicine Relationships

This cross-sectional study compares the use of telemedicine in states where COVID-19 pandemic–related licensure waivers expired vs states where waivers continued.

JAMA Netw Open. 2023;6(11):e2343697. doi:10.1001/jamanetworkopen.2023.43697
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PEDIATRICS

DOACs in Patients With Giant Coronary Artery Aneurysms After Kawasaki Disease

This case series examines outcomes among patients with giant coronary artery aneurysms after Kawasaki disease treated with direct oral anticoagulants (DOACs).

JAMA Netw Open. 2023;6(11):e2343801. doi:10.1001/jamanetworkopen.2023.43801
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PEDIATRICS

Video Education in Early Pregnancy and Parent Knowledge of Neonatal Resuscitation Options: A Secondary Analysis of a Randomized Clinical Trial

This secondary analysis of a randomized clinical trial investigates the proportion of correct answers on neonatal resuscitation options among parents after seeing a video on these options.

has multimedia
JAMA Netw Open. 2023;6(11):e2344645. doi:10.1001/jamanetworkopen.2023.44645
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HEALTH POLICY

Hospital Prices in Medicaid Managed Care

This cross-sectional study uses hospitals’ self-disclosed pricing information to characterize Medicaid managed care hospital prices.

JAMA Netw Open. 2023;6(11):e2344841. doi:10.1001/jamanetworkopen.2023.44841
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ONCOLOGY

Analysis of BRCA1- and BRCA2-Related Pancreatic Cancer and Survival

This cohort study compares the outcomes of patients with BRCA1 and BRCA-related pancreatic cancers using 2 large data sets.

JAMA Netw Open. 2023;6(11):e2345013. doi:10.1001/jamanetworkopen.2023.45013
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INFECTIOUS DISEASES

Testing for Cytomegalovirus Among Individuals Who Were Immunocompromised, 2018-2022

This cohort study investigates rates of cytomegalovirus testing before and during the COVID-19 pandemic among individuals who were immunocompromised.

JAMA Netw Open. 2023;6(11):e2345126. doi:10.1001/jamanetworkopen.2023.45126
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HEALTH POLICY

State-Level Variability in Hospital Presumptive Eligibility Programs

This cross-sectional study examines state-level variability in hospital presumptive eligibility programs to understand discrepancies in access by Medicaid expansion status.

JAMA Netw Open. 2023;6(11):e2345244. doi:10.1001/jamanetworkopen.2023.45244
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EQUITY, DIVERSITY, AND INCLUSION

Socioeconomic and Regional Disparities in Industry-Sponsored Clinical Trials in Multiple Sclerosis

This cross-sectional study examines the geographical and socioeconomic factors associated with trial distribution and outcome of treatment for multiple sclerosis (MS).

JAMA Netw Open. 2023;6(11):e2345619. doi:10.1001/jamanetworkopen.2023.45619
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open access Correction

Error in Byline

JAMA Netw Open. 2023;6(11):e2343869. doi:10.1001/jamanetworkopen.2023.43869
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Error in Byline

JAMA Netw Open. 2023;6(11):e2344113. doi:10.1001/jamanetworkopen.2023.44113
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Errors in Author Affiliations

JAMA Netw Open. 2023;6(11):e2344501. doi:10.1001/jamanetworkopen.2023.44501
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Error in Table 2

JAMA Netw Open. 2023;6(11):e2345320. doi:10.1001/jamanetworkopen.2023.45320
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Error in Byline

JAMA Netw Open. 2023;6(11):e2345388. doi:10.1001/jamanetworkopen.2023.45388
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Errors in Units

JAMA Netw Open. 2023;6(11):e2346385. doi:10.1001/jamanetworkopen.2023.46385
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Error in End Matter

JAMA Netw Open. 2023;6(11):e2346625. doi:10.1001/jamanetworkopen.2023.46625
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Errors in the Abstract

JAMA Netw Open. 2023;6(11):e2348174. doi:10.1001/jamanetworkopen.2023.48174
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JAMA Netw Open. 2023;6(11):e2344223. doi:10.1001/jamanetworkopen.2023.44223
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