October 1, 2020 Issue of JAMA Internal Medicine

October 2020, Vol 180, No. 10, Pages 1272-1405

Viewpoint

Policy Implications of the Orphan Drug Designation for Remdesivir to Treat COVID-19

Kao-Ping Chua, MD, PhD; Rena M. Conti, PhD

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1273-1274. doi:10.1001/jamainternmed.2020.2759

This Viewpoint highlights loopholes in US orphan drug policy as exemplified by the use of remdesivir to treat coronavirus disease 2019.

Health Care Policy and Law

The Affordable Care Act Returns to the Supreme Court: Maine Community Health Options v United States

Marcia M. Boumil, JD, LLM; Gregory Curfman, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1275-1276. doi:10.1001/jamainternmed.2020.3549

This Viewpoint examines the consequences of the government withholding on its monetary promises made to private insurance companies owing to the passing of the Affordable Care Act.

Perspective

Physician Work Environment and Well-Being

Dystopian Diary of a Medical Resident

Allison Sarah Vise, MD

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1277. doi:10.1001/jamainternmed.2020.2780

This essay describes the author鈥檚 adaptations to dystopian changes in hospital procedures and the reverberations throughout her life brought on by the COVID-19 pandemic.

Physician Work Environment and Well-Being

Thank You for Your Flexibility During These Unprecedented Times

Amy Ou, MD; Christian L. Torres, MD; Milna Rufin, MD

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1278-1279. doi:10.1001/jamainternmed.2020.3020

This essay discusses chief residents鈥� experience at a large internal medicine program in New York City during the coronavirus disease 2019 pandemic.

Original Investigation

Group-Based vs Individual Pelvic Floor Muscle Training to Treat Urinary Incontinence in Older Women: A Randomized Clinical Trial

Chantale Dumoulin, PhD; Mélanie Morin, PhD; Coraline Danieli, PhD; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1284-1293. doi:10.1001/jamainternmed.2020.2993

This randomized clinical trial demonstrates that outcomes of women participating in group-based pelvic floor muscle training are not inferior to outcomes of women receiving individualized training.

Diagnostic Accuracy of Symptoms, Physical Signs, and Laboratory Tests for Giant Cell Arteritis: A Systematic Review and Meta-analysis

Kornelis S. M. van der Geest, MD, PhD; Maria Sandovici, MD, PhD; Elisabeth Brouwer, MD, PhD; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1295-1304. doi:10.1001/jamainternmed.2020.3050

This systematic review and meta-analysis evaluate the diagnostic accuracy of symptoms, physical signs, and laboratory tests in patients with suspected giant cell arteritis.

Effect of Sustained-Release Morphine for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease on Health Status: A Randomized Clinical Trial

Cornelia A. Verberkt, MSc; Marieke H. J. van den Beuken-van Everdingen, MD, PhD; Jos M. G. A. Schols, MD, PhD; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1306-1314. doi:10.1001/jamainternmed.2020.3134

This randomized clinical trial evaluates the health effects of using oral sustained-release morphine to treat moderate to very severe breathlessness in patients with advanced chronic obstructive pulmonary disease.

Less Is More

Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018

Rohan Khera, MD, MS; Eric A. Secemsky, MD, MSc; Yongfei Wang, MS; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1317-1327. doi:10.1001/jamainternmed.2020.3276

This cohort study evaluates patterns in the use of multivessel vs culprit-vessel percutaneous coronary intervention in acute myocardial infarction and cardiogenic shock in the US from 2009 to 2018.

Editorial
Multivessel or Culprit Vessel鈥揙nly Percutaneous Coronary Intervention for Patients With Acute Myocardial Infarction and Cardiogenic Shock: Real-World Evidence in Support of CULPRIT-SHOCK
Colette DeJong, MD; Rita F. Redberg, MD

JAMA Intern Med

Trends in Emergency Department Visits and Hospital Admissions in Health Care Systems in 5 States in the First Months of the COVID-19 Pandemic in the US

Molly M. Jeffery, PhD; Gail D鈥橭nofrio, MD, MS; Hyung Paek, MD; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1328-1333. doi:10.1001/jamainternmed.2020.3288

This cross-sectional study examines trends in emergency department visits and visits that led to hospitalizations during a 4-month period leading up to and during the COVID-19 outbreak in the US.

Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020

Daniel M. Weinberger, PhD; Jenny Chen, BS; Ted Cohen, MD, DPH; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1336-1344. doi:10.1001/jamainternmed.2020.3391

This observational study uses NCHS data to evaluate weekly changes in US deaths due to any cause and deaths due to pneumonia, influenza, or COVID-19, by state, from March 1 through May 30, 2020.

Podcast: Estimation of Excess Deaths From COVID-19 in the United States, March to May 2020

Editorial
Mortality and Morbidity: The Measure of a Pandemic
Jody W. Zylke, MD; Howard Bauchner, MD

JAMA
- Podcast: Estimation of Excess Deaths From COVID-19 in the United States, March to May 2020

Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy

Giacomo Grasselli, MD; Massimiliano Greco, MD; Alberto Zanella, MD; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1345-1355. doi:10.1001/jamainternmed.2020.3539

This cohort study evaluates the independent risk factors associated with mortality of patients with COVID-19 requiring treatment in the intensive care unit in the Lombardy region of Italy.

Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China

Fan Wu, PhD; Mei Liu, MS; Aojie Wang, MS; et al.

Abstract Full Text

open access

JAMA Intern Med. 2020;180(10):1356-1362. doi:10.1001/jamainternmed.2020.4616

This cohort study examines the levels of neutralizing antibodies to severe acute respiratory syndrome coronavirus 2 in patients who recovered from mild coronavirus disease 2019.

Editor's Note
Neutralizing Antibodies Against SARS-CoV-2鈥擨mportant Questions, Unclear Answers
Mitchell H. Katz, MD

JAMA Intern Med

Editorial

Less Is More

Multivessel or Culprit Vessel鈥揙nly Percutaneous Coronary Intervention for Patients With Acute Myocardial Infarction and Cardiogenic Shock: Real-World Evidence in Support of CULPRIT-SHOCK

Colette DeJong, MD; Rita F. Redberg, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1280-1283. doi:10.1001/jamainternmed.2020.3400

Invited Commentary

Pelvic Floor Therapy for Older Women With Urinary Incontinence鈥擟an Group-Based Training Reduce the Population-Level Burden of This Condition?

Alison J. Huang, MD, MAS

Abstract Full Text

JAMA Intern Med. 2020;180(10):1293-1294. doi:10.1001/jamainternmed.2020.2983

Clinical Diagnosis鈥擨s There Any Other Type?

Gurpreet Dhaliwal, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1304-1305. doi:10.1001/jamainternmed.2020.3048

The Role of Opioids in Patients With Chronic Obstructive Pulmonary Disease and Chronic Breathlessness

Eric W. Widera, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1315-1316. doi:10.1001/jamainternmed.2020.3133

Learning From the Decrease in US Emergency Department Visits in Response to the Coronavirus Disease 2019 Pandemic

David L. Schriger, MD, MPH

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1334-1335. doi:10.1001/jamainternmed.2020.3265

Less Is More

Screening Asymptomatic Kidney Transplant Candidates鈥�Primum Non Nocere

Joshua A. Beckman, MD; Matthew D. McEvoy, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1366-1367. doi:10.1001/jamainternmed.2020.2674

Less Is More

The Problem of Daily Imaging in the Intensive Care Unit: When You Care So Much It Hurts

Christopher G. Choukalas, MD, MS; Thanh-Giang Vu, MD

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1369-1370. doi:10.1001/jamainternmed.2020.2667

Editor's Note

Neutralizing Antibodies Against SARS-CoV-2鈥擨mportant Questions, Unclear Answers

Mitchell H. Katz, MD

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1362. doi:10.1001/jamainternmed.2020.4624

Time to End 鈥淢anels鈥� in Clinical Trial Leadership

Tracy Y. Wang, MD, MHS, MSc; Jacqueline Talea DesJardin, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1383-1384. doi:10.1001/jamainternmed.2020.2489

Setting Expectations for Clinical Research During the COVID-19 Pandemic

James W Salazar, MD, MAS; J. Michael McWilliams Jr, MD, PhD; Tracy Y. Wang, MD, MHS, MSc

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1400-1401. doi:10.1001/jamainternmed.2020.2882

Teachable Moment

Less Is More

Diagnostic Imaging for Breast Pain: A Teachable Moment

Colin P. Bergstrom, MD; Neil Keshvani, MD; Suzanne D. Conzen, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1363-1364. doi:10.1001/jamainternmed.2020.2432

This Teachable Moment suggests that diagnostic imaging is unnecessary in most patients with breast pain, particularly in those with normal examination results and no family history of breast cancer.

Less Is More

Time to Rethink Surveillance Testing Prior to Kidney Transplant: A Teachable Moment

Mohammed Ruzieh, MD; Andrew J. Foy, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1365-1366. doi:10.1001/jamainternmed.2020.2668

This Teachable Moment describes a patient awaiting kidney transplant who underwent a preoperative stress test.

Less Is More

Low-Value Diagnostic Imaging in the Intensive Care Unit: A Teachable Moment

Jason H. Maley, MD; Jennifer P. Stevens, MD, MS

Abstract Full Text

JAMA Intern Med. 2020;180(10):1368-1369. doi:10.1001/jamainternmed.2020.2681

This Teachable Moment discusses potential problems arising from interpretation of routine daily chest radiographs that are ordered without specific clinical indication for patients requiring mechanical ventilators.

Preventing Opioid-Induced Constipation: A Teachable Moment

Srishti Saha, MD; Piyush Nathani, MD; Arjun Gupta, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1371-1372. doi:10.1001/jamainternmed.2020.3285

This Teachable Moment discusses opioid-induced constipation and preventive strategies.

Less Is More

Overuse of Respiratory Viral Panels: A Teachable Moment

Anya Greenberg, MBA; Peter Barish, MD; Ari Hoffman, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1373-1374. doi:10.1001/jamainternmed.2020.3535

This Teachable Moment describes a woman in her 40s with a medical history of recurrent ear infections who presented to the emergency department with one day of left ear pain, nausea, and vomiting.

Research Letter

Representation of Women in Cardiovascular Clinical Trial Leadership

Kara J. Denby, MD; Natalie Szpakowski, MD; Julie Silver, MD; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1382-1383. doi:10.1001/jamainternmed.2020.2485

This quality improvement study describes representation of women within leadership committees of clinical trials and in lead authorship positions of ensuing cardiovascular trial publications.

Editor's Note
Time to End 鈥淢anels鈥� in Clinical Trial Leadership
Tracy Y. Wang, MD, MHS, MSc; Jacqueline Talea DesJardin, MD

JAMA Intern Med

US Hydroxychloroquine, Chloroquine, and Azithromycin Outpatient Prescription Trends, October 2019 Through March 2020

Nadine Shehab, PharmD, MPH; Maribeth Lovegrove, MPH; Daniel S. Budnitz, MD, MPH

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1384-1386. doi:10.1001/jamainternmed.2020.2594

This study examines how the prescription of hydroxychloroquine and chloroquine to outpatients has changed in the United States during the coronavirus disease 2019 pandemic.

Health Care Policy and Law

Assessment of Disparities in Digital Access Among Medicare Beneficiaries and Implications for Telemedicine

Eric T. Roberts, PhD; Ateev Mehrotra, MD, MPH

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1386-1389. doi:10.1001/jamainternmed.2020.2666

This cross-sectional study uses data from the 2018 American Community Survey to assess disparities in digital access among Medicare beneficiaries by demographic and socioeconomic characteristics.

Health Care Policy and Law

Assessing Telemedicine Unreadiness Among Older Adults in the United States During the COVID-19 Pandemic

Kenneth Lam, MD; Amy D. Lu, MD; Ying Shi, PhD; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1389-1391. doi:10.1001/jamainternmed.2020.2671

This cross-sectional study uses 2018 data from the National Health and Aging Trends Study to assess the prevalence among older adults in the United States of unreadiness to access video or telephone telemedicine because of disability or inexperience with technology.

Gender Differences in Endowed Chairs in Medicine at Top Schools

Jessica A. Gold, MD, MS; Danielle Roubinov, PhD; Lena S. Jia, MPHS; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1391-1394. doi:10.1001/jamainternmed.2020.2677

This cross-sectional study examines the gender distribution of endowed chairs in departments of medicine and the association of gender with holding an endowed chair.

Trends in e-Cigarette Use in Adults in the United States, 2016-2018

Olufunmilayo H. Obisesan, MD, MPH; Albert D. Osei, MD, MPH; S. M. Iftekhar Uddin, MBBS, MSPH; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1394-1398. doi:10.1001/jamainternmed.2020.2817

This cross-sectional study uses data from the Behavioral Risk Factor Surveillance System to assess trends in e-cigarette use in the United States.

Characteristics and Strength of Evidence of COVID-19 Studies Registered on ClinicalTrials.gov

Krishna Pundi, MD; Alexander C. Perino, MD; Robert A. Harrington, MD; et al.

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1398-1400. doi:10.1001/jamainternmed.2020.2904

This cross-sectional study evaluates the characteristics and expected strength of evidence of coronavirus disease 2019 studies registered on ClinicalTrials.gov.

Editor's Note
Setting Expectations for Clinical Research During the COVID-19 Pandemic
James W Salazar, MD, MAS; J. Michael McWilliams Jr, MD, PhD; Tracy Y. Wang, MD, MHS, MSc

JAMA Intern Med

Challenges in Clinical Electrocardiography

Tachycardia in a Patient With Heart Failure: Telemetry Tales

Naga Venkata Pothineni, MD; Swathi Kovelamudi, MD; Hakan Paydak, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1375-1377. doi:10.1001/jamainternmed.2020.2455

This case report presents the electrocardiographic findings of a woman in her 60s with symptoms of worsening dyspnea on exertion and pedal edema.

External Automated Defibrillator鈥揂ssisted Diagnosis of Patient After Bringing Him Back to Life

José de Almeida, MD; Francisco Gonçalves, MD; Lino Gonçalves, MD, PhD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1378-1379. doi:10.1001/jamainternmed.2020.2549

This case report describes a young man with no previous disease who was found dead and subsequently revived using an automated external defibrillator.

The Weak LINQ鈥擟ontinuous Rhythm Monitoring During Sudden Death

Emily R. Siegel, BS; James W. Salazar, MD, MAS; Zian H. Tseng, MD, MAS

Abstract Full Text

JAMA Intern Med. 2020;180(10):1380-1381. doi:10.1001/jamainternmed.2020.2630

This case report describes a person in their 70s found unconscious and unresponsive who had a history of hypertension, dyslipidemia, atrial fibrillation, seizure disorder, and coronary artery disease and an implantable loop recorder placed 6 months prior.

Comment & Response

Medicaid Expansion and Rates of Opioid-Related Hospital Use

Arshjot Khokhar, BS; Anuj V. Mehta, BS; Kenneth John, MD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1401-1402. doi:10.1001/jamainternmed.2020.2740

Medicaid Expansion and Rates of Opioid-Related Hospital Use鈥擱eply

Aparna Soni, PhD

Abstract Full Text

JAMA Intern Med. 2020;180(10):1402-1403. doi:10.1001/jamainternmed.2020.2737

Weight Management and Healthy Lifestyles

Theodore K. Kyle, RPh, MBA; Joseph F. Nadglowski, BA; Fatima Cody Stanford, MD, MPH, MPA

Abstract Full Text

JAMA Intern Med. 2020;180(10):1403. doi:10.1001/jamainternmed.2020.2743

Weight Management and Healthy Lifestyles

Katherine D. Hoerster, PhD, MPH; Kristen Gray, PhD, MS; Susan D. Raffa, PhD

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1403-1404. doi:10.1001/jamainternmed.2020.2765

Weight Management and Healthy Lifestyles鈥擱eply

Solja T. Nyberg, PhD; Archana Singh-Manoux, PhD; Mika Kivimäki, PhD

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1404-1405. doi:10.1001/jamainternmed.2020.2762

Correction

Error in Abstract Results

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1405. doi:10.1001/jamainternmed.2020.5576

Errors in the Text

Abstract Full Text

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JAMA Intern Med. 2020;180(10):1405. doi:10.1001/jamainternmed.2020.5608

Editorial
Multivessel or Culprit Vessel鈥揙nly Percutaneous Coronary Intervention for Patients With Acute Myocardial Infarction and Cardiogenic Shock: Real-World Evidence in Support of CULPRIT-SHOCK
Colette DeJong, MD; Rita F. Redberg, MD

JAMA Intern Med

October 2024 - January 1908

Decade

Year

Issue

October 2020, Vol 180, No. 10, Pages 1272-1405

Health Care Policy and Law

Physician Work Environment and Well-Being

Physician Work Environment and Well-Being

Less Is More

Less Is More

Less Is More

Less Is More

Less Is More

Less Is More

Less Is More

Less Is More

Health Care Policy and Law

Health Care Policy and Law