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Issue

December 2018, Vol 178, No. 12, Pages 1573-1736

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1573-1736. doi:10.1001/jamainternmed.2017.5244
Viewpoint

Probiotic Safety—No Guarantees

Abstract Full Text
JAMA Intern Med. 2018;178(12):1577-1578. doi:10.1001/jamainternmed.2018.5403

This Viewpoint examines the risks and benefits of consuming probiotic products and current labelling practices in the United States.

Less Is More

Does the Term Intensive Care Unit Promote Aggressive Treatment?

Abstract Full Text
JAMA Intern Med. 2018;178(12):1579-1580. doi:10.1001/jamainternmed.2018.5400

This Viewpoint examines how the term intensive care unit may contribute to patient and physician expectations of more invasive and aggressive therapies, and suggests that a change in the nomenclature may be a first step in realigning patient and physician expectations from burdensome treatment towoard a more patient-centered approach.

Health Care Reform

Dialysis for Patients With End-stage Renal Disease Who Are Homeless

Abstract Full Text
JAMA Intern Med. 2018;178(12):1581-1582. doi:10.1001/jamainternmed.2018.5470

This Viewpoint highlights the challenges faced by patients with end-stage renal disease who are homeless, recommends measures to determine the prevalence and outcomes of homelessness among Medicare beneficiaries with end-stage renal disease, and proposes approaches to improve outcomes through supportive housing.

Editorial

Addressing Intimate Partner Violence and Abuse of Older or Vulnerable Adults in the Health Care Setting—Beyond Screening

Abstract Full Text
JAMA Intern Med. 2018;178(12):1583-1585. doi:10.1001/jamainternmed.2018.6523
Original Investigation

Evaluating Progression-Free Survival as a Surrogate Outcome for Health-Related Quality of Life in Oncology: A Systematic Review and Quantitative Analysis

Abstract Full Text
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JAMA Intern Med. 2018;178(12):1586-1596. doi:10.1001/jamainternmed.2018.4710

This systematic review and quantitative analysis evaluates progression-free survival as a surrogate outcome for health-related quality of life in oncology.

Association of Frequency of Organic Food Consumption With Cancer Risk: Findings From the NutriNet-Santé Prospective Cohort Study

Abstract Full Text
free access has audio
JAMA Intern Med. 2018;178(12):1597-1606. doi:10.1001/jamainternmed.2018.4357

This population-based cohort study investigates the association between organic food consumption and the risk of cancer in a large cohort of French adults.

Combustible and Electronic Tobacco and Marijuana Products in Hip-Hop Music Videos, 2013-2017

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1608-1615. doi:10.1001/jamainternmed.2018.4488

This content analysis of 796 hip-hop music videos assesses the prevalence of electronic tobacco and marijuana products and brand placement in the most popular music videos from 2013 to 2017.

Engaging Diverse English- and Spanish-Speaking Older Adults in Advance Care Planning: The PREPARE Randomized Clinical Trial

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1616-1625. doi:10.1001/jamainternmed.2018.4657

This randomized clinical trial compares the efficacy of a patient-directed, online advance care planning program plus an easy-to-read advance directive with that of an advance directive alone to increase advance care planning and patient-reported engagement among English- and Spanish-speaking populations.

Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension

Abstract Full Text
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JAMA Intern Med. 2018;178(12):1626-1634. doi:10.1001/jamainternmed.2018.4684

This cohort study uses electronic health record data from the Clinical Practice Research Datalink database to examine the association between antihypertensive treatment prescriptions and all-cause mortality, cardiovascular disease, and adverse events in low-risk patients with mild hypertension.

Effect of Community Health Worker Support on Clinical Outcomes of Low-Income Patients Across Primary Care Facilities: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1635-1643. doi:10.1001/jamainternmed.2018.4630

This randomized clinical trial evaluates the effectiveness of IMPaCT, a patient-centered program that uses trained community health workers to assist patients receiving treatment at 3 different facilities with the socioeconomic and behavioral aspects of their health.

Evaluation of Interventions Intended to Increase Colorectal Cancer Screening Rates in the United States: A Systematic Review and Meta-analysis

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1645-1658. doi:10.1001/jamainternmed.2018.4637

This systematic review and meta-analysis examines interventions used to increase the rates of colorectal cancer screening tests.

Association of Short Interpregnancy Interval With Pregnancy Outcomes According to Maternal Age

Abstract Full Text
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JAMA Intern Med. 2018;178(12):1661-1670. doi:10.1001/jamainternmed.2018.4696

This population-based cohort study examines the risk of maternal mortality or severe morbidity, adverse fetal and infant outcomes, and spontaneous preterm delivery after short interpregnancy intervals in both younger and older Canadian women.

Less Is More

Assessment of Attitudes Toward Deprescribing in Older Medicare Beneficiaries in the United States

Abstract Full Text
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JAMA Intern Med. 2018;178(12):1673-1680. doi:10.1001/jamainternmed.2018.4720

This population-based survey study uses data from the US National Health and Aging Trends Study to describe the attitudes of older Medicare beneficiaries toward deprescribing and whether individual characteristics are associated with these attitudes.

Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With Outcomes After Acute Kidney Injury

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1681-1690. doi:10.1001/jamainternmed.2018.4749

This study uses data from the Alberta Kidney Disease Network population database to evaluate the association of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use with posthospitalization outcomes in patients with acute kidney injury.

Invited Commentary

Organic Foods for Cancer Prevention—Worth the Investment?

Abstract Full Text
has audio
JAMA Intern Med. 2018;178(12):1606-1607. doi:10.1001/jamainternmed.2018.4363

How Community Health Workers Can Affect Health Care

Abstract Full Text
JAMA Intern Med. 2018;178(12):1643-1644. doi:10.1001/jamainternmed.2018.4626

Colorectal Cancer Control: Where Have We Been and Where Should We Go Next?

Abstract Full Text
JAMA Intern Med. 2018;178(12):1658-1660. doi:10.1001/jamainternmed.2018.4627

Balancing the Risks and Desires for Pregnancy in Older Mothers: Increasing Morbidity, Declining Fertility

Abstract Full Text
JAMA Intern Med. 2018;178(12):1671-1672. doi:10.1001/jamainternmed.2018.4734

Use of Renin Angiotensin System Blockers After Acute Kidney Injury: Balancing Tradeoffs

Abstract Full Text
JAMA Intern Med. 2018;178(12):1690-1692. doi:10.1001/jamainternmed.2018.4757

Sodium Restriction in Heart Failure: Too Much Uncertainty—Do the Trials

Abstract Full Text
JAMA Intern Med. 2018;178(12):1700-1701. doi:10.1001/jamainternmed.2018.4653

Making It Easier for Hospitals to Participate in, and Succeed Under, Bundled Payments

Abstract Full Text
JAMA Intern Med. 2018;178(12):1717-1719. doi:10.1001/jamainternmed.2018.4739
Editor's Note

Decreased Admission Rate From the Emergency Department With Increased Emergency Department Visits—The Good and the Bad

Abstract Full Text
JAMA Intern Med. 2018;178(12):1710-1711. doi:10.1001/jamainternmed.2018.5163

Continuing Problems With Financial Conflicts of Interest and Clinical Practice Guidelines

Abstract Full Text
JAMA Intern Med. 2018;178(12):1715. doi:10.1001/jamainternmed.2018.4974

The Persistent Problem of Overuse of Diagnostic Testing Among House Staff—Time to Move Forward

Abstract Full Text
JAMA Intern Med. 2018;178(12):1721. doi:10.1001/jamainternmed.2018.3503

Regulating the Dietary Supplement Industry: The Taming of the Slew

Abstract Full Text
JAMA Intern Med. 2018;178(12):1723. doi:10.1001/jamainternmed.2018.5097
Review

Reduced Salt Intake for Heart Failure: A Systematic Review

Abstract Full Text
JAMA Intern Med. 2018;178(12):1693-1700. doi:10.1001/jamainternmed.2018.4673

This systematic review assessed the evidence suggesting that reduced dietary salt intake benefits patients with heart failure in randomized clinical trials.

Teachable Moment

Less Is More

Inappropriate Use of Fecal Occult Blood Testing

Abstract Full Text
JAMA Intern Med. 2018;178(12):1702-1703. doi:10.1001/jamainternmed.2018.5553

This Teachable Moment describes the case of a 58-year-old man with bilateral knee osteoarthritis who presented to the emergency department with 1 week of dizziness and intermittent dark stools.

Challenges in Clinical Electrocardiography

Electrical Alternans in Disguise—A Curious Case of Atrial Flutter

Abstract Full Text
JAMA Intern Med. 2018;178(12):1704-1705. doi:10.1001/jamainternmed.2018.5291

This case report describes the occurrence of atrial flutter presenting on an electrocardiogram as electrical alternans.

Research Letter

Financial Burden of Employer-Sponsored High-Deductible Health Plans for Low-Income Adults With Chronic Health Conditions

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1706-1708. doi:10.1001/jamainternmed.2018.4706

This cohort study examines the prevalence of high out-of-pocket health care spending across health plans with different deductible levels among adults in low-income families who have chronic conditions.

Trends in Emergency Department Visits and Admission Rates Among US Acute Care Hospitals

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1708-1710. doi:10.1001/jamainternmed.2018.4725

This observational study describes trends in emergency department visits and admission rates among US acute care hospitals using data from the National Emergency Department Survey.

Health Care Policy and Law

Evaluation of Industry Relationships Among Authors of Clinical Practice Guidelines in Gastroenterology

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1711-1712. doi:10.1001/jamainternmed.2018.4730

This study examines the prevalence of conflicts of interest among authors of clinical practice guidelines and failure to accurately report financial relationships among authors and industry.

Prevalence of Financial Conflicts of Interest Among Authors of Clinical Guidelines Related to High-Revenue Medications

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1712-1715. doi:10.1001/jamainternmed.2018.5106

This study examines the presence and extent of undeclared financial conflicts of interest among authors of clinical practice guidelines related to high-revenue medications.

Health Care Policy and Law

Characteristics of Hospitals Exiting the Newly Voluntary Comprehensive Care for Joint Replacement Program

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1715-1717. doi:10.1001/jamainternmed.2018.4743

This survey of Medicare claims data compares the medical and financial performance of hospitals that exited and hospitals that remained in the Comprehensive Care for Joint Replacement Program.

Less Is More

Analysis of Diagnostic Test Ordering Habits Among Internal Medicine Residents

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1719-1721. doi:10.1001/jamainternmed.2018.3519

This study analyzes electronic diagnostic test ordering habits of internal medicine resident physicians at an academic medical center and during academic year 2016-2017.

Prohibited Stimulants in Dietary Supplements After Enforcement Action by the US Food and Drug Administration

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1721-1723. doi:10.1001/jamainternmed.2018.4846

This analysis of dietary supplements purchased in 2014 and purchased again in 2017 examines whether stimulants that were initially present were still present after issuance of public notices by the US Food and Drug Administration to remove potentially hazardous ingredients.

Comment & Response

The Alleged Health-Protective Effects of Coffee

Abstract Full Text
JAMA Intern Med. 2018;178(12):1723-1724. doi:10.1001/jamainternmed.2018.5798

The Alleged Health-Protective Effects of Coffee

Abstract Full Text
JAMA Intern Med. 2018;178(12):1724-1725. doi:10.1001/jamainternmed.2018.5807

The Alleged Health-Protective Effects of Coffee

Abstract Full Text
JAMA Intern Med. 2018;178(12):1725. doi:10.1001/jamainternmed.2018.5810

The Alleged Health-Protective Effects of Coffee

Abstract Full Text
JAMA Intern Med. 2018;178(12):1725-1726. doi:10.1001/jamainternmed.2018.6071

The Alleged Health-Protective Effects of Coffee—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(12):1726. doi:10.1001/jamainternmed.2018.6545

The Alleged Health-Protective Effects of Coffee—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(12):1726-1727. doi:10.1001/jamainternmed.2018.5795

Poor Sleep in Hospitalized Patients: Are Hospital-Related Factors at Fault?

Abstract Full Text
JAMA Intern Med. 2018;178(12):1727-1728. doi:10.1001/jamainternmed.2018.6152

Poor Sleep in Hospitalized Patients: Are Hospital-Related Factors at Fault?—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(12):1728-1729. doi:10.1001/jamainternmed.2018.6159

Discharge Home From Critical Care: Comparing Different Health Care Systems

Abstract Full Text
JAMA Intern Med. 2018;178(12):1729. doi:10.1001/jamainternmed.2018.6533

Discharge Home From Critical Care: Comparing Different Healthcare Systems—Reply

Abstract Full Text
JAMA Intern Med. 2018;178(12):1729-1730. doi:10.1001/jamainternmed.2018.6548

Updated Disclosure Statement for Invited Commentary

Abstract Full Text
JAMA Intern Med. 2018;178(12):1730. doi:10.1001/jamainternmed.2018.7330

Protocol Deviations, Reanalyses, and Corrections to Derivative Studies of the PREDIMED Trial

Abstract Full Text
JAMA Intern Med. 2018;178(12):1730-1731. doi:10.1001/jamainternmed.2018.6456
Correction

Updated Disclosure Statement for Invited Commentary

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1731. doi:10.1001/jamainternmed.2018.7305

Protocol Deviations and Reanalyses in Derivative Studies of the PREDIMED Trial

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1731-1732. doi:10.1001/jamainternmed.2018.6460

Errors in Figures

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1732. doi:10.1001/jamainternmed.2018.5747

Incorrect Colors in Figure Keys

Abstract Full Text
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JAMA Intern Med. 2018;178(12):1732. doi:10.1001/jamainternmed.2018.6618

Rewording of Conclusions and Corrected Data in Table 1

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1732. doi:10.1001/jamainternmed.2018.6902

Omitted Funding Source

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1732. doi:10.1001/jamainternmed.2018.7341
Images From Our Readers

East River Greenway, New York City

Abstract Full Text
JAMA Intern Med. 2018;178(12):1735. doi:10.1001/jamainternmed.2018.5390
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
free access
JAMA Intern Med. 2018;178(12):1576. doi:10.1001/jamainternmed.2017.5245
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