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Issue

September 2015, Vol 175, No. 9, Pages 1433-1588

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1433-1435. doi:10.1001/jamainternmed.2014.5084
Viewpoint

Medicine in a Disaster Area: Lessons From the 2015 Earthquake in Nepal

Abstract Full Text
JAMA Intern Med. 2015;175(9):1437-1438. doi:10.1001/jamainternmed.2015.3985

This Viewpoint identifies strategies for the appropriate and efficient emergency medical team assistance to other countries following natural disasters.

Less Is More

The Divide Between Breast Density Notification Laws and Evidence-Based Guidelines for Breast Cancer Screening: Legislating Practice

Abstract Full Text
JAMA Intern Med. 2015;175(9):1439-1440. doi:10.1001/jamainternmed.2015.3040

This Viewpoint considers that breast density notification laws are unlikely to improve our understanding of breast cancer risk, screening, and diagnosis or to save lives and instead may result in substantial personal harms and societal costs.

Inside Story

Less Is More

鈥淢om, You Have to Trust Me鈥

Abstract Full Text
JAMA Intern Med. 2015;175(9):1441. doi:10.1001/jamainternmed.2015.3659

Less Is More

Listen Doctor, the Patient Just Might Be Right

Abstract Full Text
JAMA Intern Med. 2015;175(9):1442-1443. doi:10.1001/jamainternmed.2015.2708
Original Investigation

Cognitive Tests to Detect Dementia: A Systematic Review and Meta-analysis

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1450-1458. doi:10.1001/jamainternmed.2015.2152

This systematic review and meta-analysis suggest that the Mini-Cog test and Addenbrooke鈥檚 Cognitive Examination鈥揜evised are the best screening tests for dementia.

Cognitive Behavioral Therapy for Insomnia Comorbid With Psychiatric and Medical Conditions: A Meta-analysis

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1461-1472. doi:10.1001/jamainternmed.2015.3006

This meta-analysis evaluates the use of cognitive behavioral therapy for treatment of insomnia in patients with comorbid medical or psychiatric conditions.

Long-term Clinical Outcomes of Splanchnic Vein Thrombosis: Results of an International Registry

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1474-1480. doi:10.1001/jamainternmed.2015.3184

This cohort study evaluates the long-term outcomes of splanchnic vein thrombosis in patients with differing risk factors and treatments.

Less Is More

Breast Cancer Screening, Incidence, and Mortality Across US Counties

Abstract Full Text
free access has audio
JAMA Intern Med. 2015;175(9):1483-1489. doi:10.1001/jamainternmed.2015.3043

This ecological study using data from the SEER cancer registries examines the associations between rates of mammography screening and the incidence of breast cancer, mortality from breast cancer, and tumor size.

Information Sharing Preferences of Older Patients and Their Families

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1492-1497. doi:10.1001/jamainternmed.2015.2903

This qualitative study examines how patients older than 75 years share their health information with their caregivers, as well as how elderly patients and their caregivers approach the spectrum of health information sharing and control.

Industry Relationships Among Academic Institutional Review Board Members: Changes From 2005 Through 2014

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1500-1506. doi:10.1001/jamainternmed.2015.3167

This survey study examined the nature, extent, and perceived consequences of industry relationships among institutional review board members in academic health centers and compared the results with findings from 2005.

Primary Care Provider-Delivered Smoking Cessation Interventions and Smoking Cessation Among Participants in the National Lung Screening Trial

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1509-1516. doi:10.1001/jamainternmed.2015.2391

This case-control study found that when physicians assisted and arranged follow-up for smokers, rates of quitting smoking increased.

Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1518-1526. doi:10.1001/jamainternmed.2015.3528

This population-based study looks at the development of autoimmune diseases in first-degree relatives and spouses of patients with systemic lupus erythematosus.

Attitudes and Perceptions About Smoking Cessation in the Context of Lung Cancer Screening

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1530-1537. doi:10.1001/jamainternmed.2015.3558

This qualitative interview study reports how the availability of lung cancer screening influenced current smokers鈥 motivation regarding smoking cessation.

Clinical and Radiologic Disease in Smokers With Normal Spirometry

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1539-1549. doi:10.1001/jamainternmed.2015.2735

Among individuals from the COPDGene cross-sectional observational study, clinical and radiologic evidence of smoking-related disease was identified in a cohort of current and former smokers who did not meet spirometric criteria for chronic obstructive pulmonary disease.

Health Care Reform

Allopurinol Use and Risk of Fatal Hypersensitivity Reactions: A Nationwide Population-Based Study in Taiwan

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1550-1557. doi:10.1001/jamainternmed.2015.3536

This retrospective nationwide population study conducted using data from the Taiwan National Health Insurance Research Database investigates the incidence of, risk factors for, and mortality associated with allopurinol hypersensitivity in new users of allopurinol.

Invited Commentary

Copyright and Bedside Cognitive Testing: Why We Need Alternatives to the Mini-Mental State Examination

Abstract Full Text
JAMA Intern Med. 2015;175(9):1459-1460. doi:10.1001/jamainternmed.2015.2159

Treating Insomnia Disorder in the Context of Medical and Psychiatric Comorbidities

Abstract Full Text
JAMA Intern Med. 2015;175(9):1472-1473. doi:10.1001/jamainternmed.2015.3015

The Subtle Benefit of Anticoagulant Therapy for Splanchnic Vein Thrombosis

Abstract Full Text
JAMA Intern Med. 2015;175(9):1481-1482. doi:10.1001/jamainternmed.2015.3196

The commentary discusses the implications of the study on anticoagulant therapy for splanchnic vein thrombosis from the International Society on Thrombosis and Hemostasis registry.

Effect of Screening Mammography on Cancer Incidence and Mortality

Abstract Full Text
JAMA Intern Med. 2015;175(9):1490-1491. doi:10.1001/jamainternmed.2015.3056

A User-Centered Design Approach to Information Sharing for Older Patients and Their Families

Abstract Full Text
JAMA Intern Med. 2015;175(9):1498-1499. doi:10.1001/jamainternmed.2015.2907

Advancing Science in the Service of Humanity: Professionalism and Ethical Safeguards

Abstract Full Text
JAMA Intern Med. 2015;175(9):1506-1508. doi:10.1001/jamainternmed.2015.3172

Tobacco Cessation鈥擶e Can Do Better

Abstract Full Text
JAMA Intern Med. 2015;175(9):1516-1517. doi:10.1001/jamainternmed.2015.2402

Nationwide Population Science: Lessons From the Taiwan National Health Insurance Research Database

Abstract Full Text
JAMA Intern Med. 2015;175(9):1527-1529. doi:10.1001/jamainternmed.2015.3540

Less Is More

The Psychological Effects of Lung Cancer Screening on Heavy Smokers: Another Reason for Concern

Abstract Full Text
JAMA Intern Med. 2015;175(9):1537-1538. doi:10.1001/jamainternmed.2015.3571

This Invited Commentary discusses the potential harms to heavy smokers undergoing screening for lung cancer.

Editor's Note

Reducing Life-Threatening Allopurinol Hypersensitivity

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1558. doi:10.1001/jamainternmed.2015.3546

Maximizing the EMR鈥檚 Educational Potential

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1562-1563. doi:10.1001/jamainternmed.2015.2070

Promoting Evidence-Based High-Value Health Care

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1564. doi:10.1001/jamainternmed.2015.3543

Improving Manufacturer Reporting of Adverse Events to the US Food and Drug Administration

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1566-1567. doi:10.1001/jamainternmed.2015.3574

Informed Consent and Communicating Risk and Benefits of Research on Higher-Risk Medications

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1568-1569. doi:10.1001/jamainternmed.2015.3555
Evidence to Practice

Comparative Clinical Effectiveness and Value of Novel Interferon-Free Combination Therapy for Hepatitis C Genotype 1: Summary of California Technology Assessment Forum Report

Abstract Full Text
JAMA Intern Med. 2015;175(9):1559-1560. doi:10.1001/jamainternmed.2015.3348

This evidence report on interferon-free therapy for chronic hepatitis C virus infection includes a systematic review of the literature, a cost-effectiveness model, and a budget impact assessment to support a December 2014 public meeting of the California Technology Assessment Forum.

Teachable Moment

Less Is More

When Do Not Resuscitate Is a Nonchoice Choice: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(9):1444-1445. doi:10.1001/jamainternmed.2015.2326

This Teachable Moment describes the experience of a spouse who was asked to make the decision regarding withholding cardipulmonary resuscitation for a patient whose death from surgical complications was judged by the surgeon to be imminent.

Less Is More

Hidden Risks of Blood Transfusions: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(9):1445-1446. doi:10.1001/jamainternmed.2015.2933

In this case, a patient was exposed to several potential harms to prevent consequences of a low-risk procedure.

Less Is More

Prompt Extubation After Intensive Care Unit Procedures: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(9):1447-1448. doi:10.1001/jamainternmed.2015.3656

The earliest safe withdrawal of sedation and mechanical ventilation leads to reduced risk of complications, reduced ICU and hospital stay, as well as reduced costs and utilization of resources.

Downstream Complications of Total Parenteral Nutrition鈥擳he Domino Effect: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(9):1448-1449. doi:10.1001/jamainternmed.2015.2299

This Teachable Moment highlights the importance of advance risk-benefit analysis before initiating total parenteral nutrition administration.

Research Letter

Less Is More

A Decision Support Tool to Reduce Overtesting for Ceruloplasmin and Improve Adherence With Clinical Guidelines

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1561-1562. doi:10.1001/jamainternmed.2015.2062

This before-and-after comparison study reports that physician ordering patterns of ceruloplasmin tests decreased after a decision pop-up tool was added to the electronic medical record system at Beth Israel Deaconess Medical Center.

Less Is More

Concordance of Outpatient Esophagogastroduodenoscopy of the Upper Gastrointestinal Tract With Evidence-Based Guidelines

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1563-1564. doi:10.1001/jamainternmed.2015.3533

This study investigated the factors associated with discordance with the American College of Physician guidelines for esophagogastroduodenoscopy in adult outpatients.

Drug Manufacturers鈥 Delayed Disclosure of Serious and Unexpected Adverse Events to the US Food and Drug Administration

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1565-1566. doi:10.1001/jamainternmed.2015.3565

This study investigates patient and event characteristics associated with manufacturers鈥 delayed submission of expedited adverse event reports to the US Food and Drug Administration.

Disclosure of Boxed Warnings to Research Participants

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1567-1568. doi:10.1001/jamainternmed.2015.3552

This database review assesses the disclosure to study participants of boxed warning risks on consent forms.

Contemporary Nationwide Patterns of Active Surveillance Use for Prostate Cancer

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1569-1571. doi:10.1001/jamainternmed.2015.2835

This study examined the use of active surveillance and its predictors in prostate cancer treatment, finding that its use is low and should increase to reduce the overtreatment of screening-detected prostate cancer.

Reporting of Limitations of Observational Research

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1571-1572. doi:10.1001/jamainternmed.2015.2147

This research letter assesses the reporting limitations of observational studies published in major internal medicine journals and associated news stories, specifically focusing on inference of causality.

Retrieval of Inferior Vena Cava Filters With Prolonged Dwell Time: A Single-Center Experience in 648 Retrieval Procedures

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1572-1574. doi:10.1001/jamainternmed.2015.2561

This single-center review reports that retrieval of inferior vena cava filters after a prolonged dwell time has a high rate of safety and success in patients at risk for pulmonary embolism.

Deaths Due to Cigarette Smoking for 12 Smoking-Related Cancers in the United States

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1574-1576. doi:10.1001/jamainternmed.2015.2398

This study estimated the number of deaths attributable to cigarette smoking for 12 smoking-related cancers and found that continued progress in reducing cancer mortality requires more comprehensive tobacco control.

Comment & Response

Anticholinergic Use With Incident Dementia

Abstract Full Text
JAMA Intern Med. 2015;175(9):1577. doi:10.1001/jamainternmed.2015.2565

Anticholinergic Use With Incident Dementia鈥擱eply

Abstract Full Text
JAMA Intern Med. 2015;175(9):1577. doi:10.1001/jamainternmed.2015.2574

Working to Shift Clinician Perception

Abstract Full Text
JAMA Intern Med. 2015;175(9):1577-1578. doi:10.1001/jamainternmed.2015.3132

Dietary Sodium Intake and Risk of Cardiovascular Disease

Abstract Full Text
JAMA Intern Med. 2015;175(9):1578-1579. doi:10.1001/jamainternmed.2015.2558

Working to Shift Clinician Perceptions鈥擱eply

Abstract Full Text
JAMA Intern Med. 2015;175(9):1578. doi:10.1001/jamainternmed.2015.3135

Dietary Sodium Intake and Risk of Cardiovascular Disease

Abstract Full Text
JAMA Intern Med. 2015;175(9):1579. doi:10.1001/jamainternmed.2015.2555

Dietary Sodium Intake and Risk of Cardiovascular Disease鈥擱eply

Abstract Full Text
JAMA Intern Med. 2015;175(9):1579-1580. doi:10.1001/jamainternmed.2015.2571

Ongoing Attention to Injurious Inpatient Falls and Pressure Ulcers

Abstract Full Text
JAMA Intern Med. 2015;175(9):1580-1581. doi:10.1001/jamainternmed.2015.2549

Ongoing Attention to Injurious Inpatient Falls and Pressure Ulcers

Abstract Full Text
JAMA Intern Med. 2015;175(9):1581-1582. doi:10.1001/jamainternmed.2015.2552

Ongoing Attention to Injurious Inpatient Falls and Pressure Ulcers鈥擱eply

Abstract Full Text
JAMA Intern Med. 2015;175(9):1582. doi:10.1001/jamainternmed.2015.2568

Prescription Opioid Duration of Action and the Risk of Unintentional Overdose

Abstract Full Text
JAMA Intern Med. 2015;175(9):1582-1583. doi:10.1001/jamainternmed.2015.3256

Prescription Opioid Duration of Action and the Risk of Unintentional Overdose鈥擱eply

Abstract Full Text
JAMA Intern Med. 2015;175(9):1583. doi:10.1001/jamainternmed.2015.3259

Problems Assessing Indoor Tanning-Related Injuries

Abstract Full Text
JAMA Intern Med. 2015;175(9):1583-1584. doi:10.1001/jamainternmed.2015.3351

Problems Assessing Indoor Tanning-Related Injuries鈥擱eply

Abstract Full Text
JAMA Intern Med. 2015;175(9):1584. doi:10.1001/jamainternmed.2015.3357

In Defense of Documentary Cameras

Abstract Full Text
JAMA Intern Med. 2015;175(9):1584-1585. doi:10.1001/jamainternmed.2015.3401

In Defense of Documentary Cameras鈥擱eply

Abstract Full Text
JAMA Intern Med. 2015;175(9):1585-1586. doi:10.1001/jamainternmed.2015.3404

Better Choices Concerning Rheumatoid Factor Testing

Abstract Full Text
JAMA Intern Med. 2015;175(9):1586-1587. doi:10.1001/jamainternmed.2015.3012

Eu-estrogenemia, KNDy Neurons, and Vasomotor Symptoms

Abstract Full Text
JAMA Intern Med. 2015;175(9):1586. doi:10.1001/jamainternmed.2015.3577

A Potential Solution for Research Misconduct

Abstract Full Text
JAMA Intern Med. 2015;175(9):1587. doi:10.1001/jamainternmed.2015.3229
Correction

Error in Text and Table

Abstract Full Text
free access
JAMA Intern Med. 2015;175(9):1587-1588. doi:10.1001/jamainternmed.2015.4006

Error in Author Affiliation

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1588. doi:10.1001/jamainternmed.2015.4706
Images From Our Readers

Twilight

Abstract Full Text
JAMA Intern Med. 2015;175(9):1588. doi:10.1001/jamainternmed.2015.3354
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
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JAMA Intern Med. 2015;175(9):1436. doi:10.1001/jamainternmed.2014.5085
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