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October 30, 2024
Original Investigation

Psychometric Properties and Meaningful Change Thresholds of the Vitiligo Area Scoring Index

Abstract Full Text
open access
JAMA Dermatol. Published online October 30, 2024. doi:10.1001/jamadermatol.2024.4534

This mixed-methods study assessed the concept validity and measurement performance of the Total Vitiligo Area Scoring Index and the Facial Vitiligo Area Scoring Index and determined meaningful change thresholds in patients with nonsegmental vitiligo.

Brief Report

Low-Dose Naltrexone Use in Biopsy-Proven Lichen Planus of the Nails

Abstract Full Text
JAMA Dermatol. Published online October 30, 2024. doi:10.1001/jamadermatol.2024.4098

This case series examines the effectiveness of low-dose naltrexone in treating nail lichen planus.

Review

Impact of Clinical Information on Melanocytic Skin Lesion Pathology Diagnosis: A Scoping Review

Abstract Full Text
has active quiz
JAMA Dermatol. Published online October 30, 2024. doi:10.1001/jamadermatol.2024.4281

This scoping review examines the impact of clinical information on the histopathologic diagnosis of melanocytic skin lesions.

JAMA Dermatology Clinicopathological Challenge

Penile Persistent Yellow Plaques With Recurrent Ulcerations

Abstract Full Text
has active quiz
JAMA Dermatol. Published online October 30, 2024. doi:10.1001/jamadermatol.2024.4183

A man in his 30s presented with a painful ulcer on the ventral aspect of the penile shaft that had appeared 3 months before. Physical examination disclosed discrete penile swelling with an indurated yellowish plaque diffusely involving the ventral surface. What is your diagnosis?

Observation

Successful Treatment of Recalcitrant Chloracne With Adalimumab in an Older Man

Abstract Full Text
JAMA Dermatol. Published online October 30, 2024. doi:10.1001/jamadermatol.2024.4263

This case report describes a man in his 60s with recalcitrant chloracne caused by chlorantraniliprole, a chlorinated pesticide, exposure successfully treated with adalimumab.

Correction

Errors in Axis Labels For Figures 1 and 2

Abstract Full Text
free access
JAMA Dermatol. Published online October 30, 2024. doi:10.1001/jamadermatol.2024.4851
October 23, 2024
Original Investigation

Upadacitinib in Adolescents With Moderate to Severe Atopic Dermatitis: Analysis of 3 Phase 3 Randomized Clinical Trials Through 76 Weeks

Abstract Full Text
open access
JAMA Dermatol. Published online October 23, 2024. doi:10.1001/jamadermatol.2024.3696

This study using data from 3 phase 3 randomized clinical trials evaluates the efficacy and adverse events of upadacitinib in adolescent patients with moderate to severe atopic dermatitis through 76 weeks.

Pregabalin for Neuropathic Pain and Itch in Recessive Dystrophic Epidermolysis Bullosa: A Randomized Crossover Trial

Abstract Full Text
JAMA Dermatol. Published online October 23, 2024. doi:10.1001/jamadermatol.2024.3767

This multicenter randomized crossover trial evaluates the use of pregabalin in the treatment of neuropathic pain and itch in patients with RDEB.

Images in Dermatology

Monilethrix

Abstract Full Text
has active quiz
JAMA Dermatol. Published online October 23, 2024. doi:10.1001/jamadermatol.2024.3892

This case report describes sparse, unruly, fragile, and easily breakable hair, with patchy alopecia with diffuse follicular papules throughout the scalp as well as short hair with an alternation of darker elliptical nodes, with paler nonmedullated paler internodes giving a necklace appearance.

Research Letter

Prevalence and Patient Characteristics of Pachyonychia Congenita

Abstract Full Text
JAMA Dermatol. Published online October 23, 2024. doi:10.1001/jamadermatol.2024.3727

This cross-sectional study estimates the prevalence of genetically confirmed cases of pachyonychia congenita in Denmark.

October 16, 2024
Original Investigation

Hidradenitis Suppurativa and Maternal and Offspring Outcomes

Abstract Full Text
has audio
JAMA Dermatol. Published online October 16, 2024. doi:10.1001/jamadermatol.2024.3584

This population-based longitudinal cohort study examines the effects of maternal HS on adverse pregnancy outcomes as well as the peripartum and long-term health outcomes of mothers and their offspring.

Drug Survival of Dupilumab, Methotrexate, and Cyclosporine A in Children With Atopic Dermatitis

Abstract Full Text
JAMA Dermatol. Published online October 16, 2024. doi:10.1001/jamadermatol.2024.3717

This multicenter daily practice cohort study investigates the drug survival of dupilumab, methotrexate, and cyclosporine A in pediatric patients with atopic dermatitis.

Brief Report

Lipodermatosclerosis and Pulmonary Hypertension in Systemic Sclerosis

Abstract Full Text
JAMA Dermatol. Published online October 16, 2024. doi:10.1001/jamadermatol.2024.3929

This cohort study evaluates the association of lipodermatosclerosis with vascular outcomes, particularly pulmonary hypertension, among patients with systemic sclerosis.

October 9, 2024
Original Investigation

Genetic Susceptibility to Hidradenitis Suppurativa and Predisposition to Cardiometabolic Disease

Abstract Full Text
JAMA Dermatol. Published online October 9, 2024. doi:10.1001/jamadermatol.2024.3779

This cohort study examines the genetic association of hidradenitis suppurativa with coronary artery disease and diabetes in individuals of European ancestry from the UK Biobank.

Editor's Note

Relative, Absolute, and Excess Risk of Second Primary Melanomas Among Multiple Racial and Ethnic Groups—Analysis of Rare Events

Abstract Full Text
JAMA Dermatol. Published online October 9, 2024. doi:10.1001/jamadermatol.2024.3551
JAMA Dermatology Clinicopathological Challenge

Peristomal Erosion in a Man With Crohn Disease

Abstract Full Text
has active quiz
JAMA Dermatol. Published online October 9, 2024. doi:10.1001/jamadermatol.2024.2770

A man in his 50s with a 10-year history of Crohn disease had intermittent bowel obstructions leading to total proctocolectomy and ileostomy, and 5 weeks after surgery he developed a painful, erosive lesion around his stoma on the anterior abdominal wall. What is your diagnosis?

JAMA Dermatology Patient Page

Seborrheic Dermatitis

Abstract Full Text
free access
JAMA Dermatol. Published online October 9, 2024. doi:10.1001/jamadermatol.2024.1074

This Patient Page describes the symptoms, diagnosis, and treatment of seborrheic dermatitis.

Research Letter

Racial and Ethnic Differences in the Risk of Second Primary Melanoma

Abstract Full Text
JAMA Dermatol. Published online October 9, 2024. doi:10.1001/jamadermatol.2024.3450

This cohort study assesses the incidence of a second melanoma diagnosis after initial diagnosis among racial and ethnic minority populations.

Observation

Tralokinumab and Acitretin for the Treatment of Lamellar Ichthyosis

Abstract Full Text
JAMA Dermatol. Published online October 9, 2024. doi:10.1001/jamadermatol.2024.3443

This case report describes a man in his 30s who presented with severe and generalized congenital ichthyosis and was treated with a combination of tralokinumab and acitretin.

October 2, 2024
Original Investigation

Incidence, In-Hospital and Long-Term Mortality, and Sequelae of Epidermal Necrolysis in Adults

Abstract Full Text
JAMA Dermatol. Published online October 2, 2024. doi:10.1001/jamadermatol.2024.3575

This cohort study assesses the incidence of and compares factors associated with in-hospital and postdischarge mortality and sequelae among patients with epidermal necrolysis.

Research Letter

Validation of the Delphi Consensus Diagnostic Criteria for Necrobiotic Xanthogranuloma

Abstract Full Text
JAMA Dermatol. Published online October 2, 2024. doi:10.1001/jamadermatol.2024.3198

This diagnostic study validates the Delphi consensus diagnostic criteria for necrobiotic xanthogranuloma compared with its mimics.

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