November 1, 2022 Issue of JAMA Dermatology

November 2022, Vol 158, No. 11, Pages 1235-1333

Editorial

Resurgence of Syphilis in the US鈥擴SPSTF Reaffirms Screening Guidelines

Erin H. Amerson, MD; Herbert B. Castillo Valladares, MD, MHS; Kieron S. Leslie, MD

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1241-1243. doi:10.1001/jamadermatol.2022.3499

Editorial
The Critical Need to Modernize Syphilis Screening
Susan Tuddenham, MD, MPH; Khalil G. Ghanem, MD, PhD

JAMA
- Podcast: USPSTF Recommendation: Syphilis Screening in Nonpregnant Adolescents and Adults
Screening for Syphilis in Nonpregnant Adults and Adolescents
Ronnie M. Gravett, MD; Jeanne Marrazzo, MD, MPH

JAMA Netw Open

Difficult Dermatophytosis

Sunil Dogra, MD; M. Ramam, MD

Abstract Full Text

JAMA Dermatol. 2022;158(11):1243-1244. doi:10.1001/jamadermatol.2022.3736

Original Investigation

Assessment of the Genetic Spectrum of Uncombable Hair Syndrome in a Cohort of 107 Individuals

F. Buket Basmanav, PhD; Nicole Cesarato, MSc; Sheetal Kumar, MD; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1245-1253. doi:10.1001/jamadermatol.2022.2319

This cohort study aims to elucidate the genetic spectrum of uncombable hair syndrome among 107 included patients.

Association of Risk of Incident Venous Thromboembolism With Atopic Dermatitis and Treatment With Janus Kinase Inhibitors: A Systematic Review and Meta-analysis

Tai-Li Chen, MD; Ling-Ling Lee, PhD, RN; Huei-Kai Huang, MD; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1254-1261. doi:10.1001/jamadermatol.2022.3516

This systematic review and meta-analysis examines the risk of incident venous thromboembolism among patients with atopic dermatitis who were receiving treatment with Janus kinase inhibitors.

Association Between Inflammatory Bowel Disease and Both Psoriasis and Psoriatic Arthritis: A Bidirectional 2-Sample Mendelian Randomization Study

Dennis Freuer, PhD; Jakob Linseisen, PhD; Christa Meisinger, MD

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1262-1268. doi:10.1001/jamadermatol.2022.3682

This mendelian randomization study investigates the associations between inflammatory bowel disease, particularly Crohn disease and ulcerative colitis, and psoriasis and psoriatic arthritis.

Effect of Different Itraconazole Dosing Regimens on Cure Rates, Treatment Duration, Safety, and Relapse Rates in Adult Patients With Tinea Corporis/Cruris: A Randomized Clinical Trial

Ananta Khurana, MD; Aastha Agarwal, MD; Diksha Agrawal, MD; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1269-1278. doi:10.1001/jamadermatol.2022.3745

This randomized clinical trial compares cure rates, treatment durations, safety profiles, and relapse rates of itraconazole, 100, 200, and 400 mg/d, for the treatment of tinea corporis/cruris in adult patients.

Reevaluating Corticosteroid Classification Models in Patient Patch Testing

Joyce Y. Chen, BS; James A. Yiannias, MD; Matthew R. Hall, MD; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1279-1286. doi:10.1001/jamadermatol.2022.3774

This qualitative study uses Mayo Clinic patient data to determine copositivity patterns between corticosteroids and to evaluate against previous corticosteroid classification models.

Differences in Skin Cancer Rates by Transplanted Organ Type and Patient Age After Organ Transplant in White Patients

Lee Wheless, MD, PhD; Nimay Anand, BS; Allison Hanlon, MD, PhD; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1287-1292. doi:10.1001/jamadermatol.2022.3878

This cohort study compares the rates of development of a second or third skin cancer among transplant recipients and whether those rates vary by type of organ transplant received and age at the time of transplant.

Brief Report

Clinical Presentation and Outcome Differences Between Black Patients and Patients of Other Races and Ethnicities With Mycosis Fungoides and S茅zary Syndrome

Pamela B. Allen, MD; Subir Goyal, PhD; Tim Niyogusaba, BS; et al.

Abstract Full Text

JAMA Dermatol. 2022;158(11):1293-1299. doi:10.1001/jamadermatol.2022.3601

This cohort study assesses racial differences in presentation and outcome and identifies drivers for racial disparities among patients with mycosis fungoides and S茅zary syndrome.

Comparison of Work Relative Value Units for Outpatient Pediatric and Adult Dermatology Encounters

Krittin J. Supapannachart, MD, MPH; Zachary Wolner, MD; Allison E. Miller, MD; et al.

Abstract Full Text

JAMA Dermatol. 2022;158(11):1300-1303. doi:10.1001/jamadermatol.2022.3609

This cross-sectional study compares work relative value units generated for pediatric vs adult outpatient dermatology encounters.

Review

Credibility and Generalization of the Minimally Important Difference Concept in Dermatology: A Scoping Review

Reinhart Speeckaert, MD, PhD; Arno Belpaire, MD; Sandrine Herbelet, PhD; et al.

Abstract Full Text

has active quiz

JAMA Dermatol. 2022;158(11):1304-1314. doi:10.1001/jamadermatol.2022.3511

This scoping review evaluates the credibility and generalization of minimally important differences for patient-reported outcome measures in skin disorders.

Images in Dermatology

Netherton Syndrome

Jakob Lillemoen Drivenes, MD; Anette Bygum, DMSc

Abstract Full Text

has active quiz

JAMA Dermatol. 2022;158(11):1315. doi:10.1001/jamadermatol.2022.3796

This case report describes dry skin with marked redness of the face and hands as well as trichorrhexis invaginata.

Peutz-Jeghers Syndrome

Eri Sato, MD; Takao Goto, MD; Hitoshi Honda, MD

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1316. doi:10.1001/jamadermatol.2022.3979

This case report describes multiple dark-brown 1- to 2-mm hyperpigmented macules on the lips, nose, and conjunctivae.

JAMA Dermatology Clinicopathological Challenge

Generalized Nodules in an Older Adult Man

Jiang-Wei Cheng, MD; Ling-Xi Liu, MD; Jiu-Hong Li, MD, PhD

Abstract Full Text

has active quiz

JAMA Dermatol. 2022;158(11):1317-1318. doi:10.1001/jamadermatol.2022.4297

A man in his 60s presented with an 8-month history of pruritic papulonodular lesions on his extremities and trunk, with no significant improvement with steroids and antihistamines. What is your diagnosis?

Numerous Angiomatous Lesions in an Infant

Catherine Reilly, BS; Nidhi Shah, MD; Kaiane Habeshian, MD

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1319-1320. doi:10.1001/jamadermatol.2022.4378

A 3-month-old infant presented with bright red macules, papules, and plaques that appeared at birth and grew in size and number. What is your diagnosis?

Research Letter

Incidence of Dermatomyositis in a Nationwide Cohort Study of US Veterans

Caitlin M. Bolender, MD; Amber Jimenez, BS; Jennie T. Clarke, MD; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1321-1323. doi:10.1001/jamadermatol.2022.3112

This cohort study evaluates the incidence of dermatomyositis and its trend over time in the US Department of Veterans Affairs health care system.

Prevalence of Contact Allergens in Natural Skin Care Products From US Commercial Retailers

Peter A. Young, MPAS; Haiwen Gui, BS; Gordon H. Bae, MD

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1323-1325. doi:10.1001/jamadermatol.2022.3180

This quality improvement study assesses the prevalence of contact allergens in personal care products classified as clean or natural among 3 national retailers in the US.

Optimized User Experience, Efficiency, and Resource Use in Online Self-Management of Atopic Dermatitis

Dorian Kern, MSc; Brjánn Ljótsson, PhD; Louise Lönndahl, MD, PhD; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1325-1327. doi:10.1001/jamadermatol.2022.3434

This quality improvement study describes the revision of an internet-delivered, self-guided psychological treatment for atopic dermatitis.

Outcomes of COVID-19 and Vaccination in Patients With Moderate to Severe Atopic Dermatitis Treated With Tralokinumab

Andrew Blauvelt, MD, MBA; Andrew Pink, PhD; Margitta Worm, MD; et al.

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1327-1330. doi:10.1001/jamadermatol.2022.3488

This case series describes the outcomes of COVID-19 and SARS-CoV-2 vaccination in patients with atopic dermatitis who have been treated with tralokinumab.

Observation

Treatment of Warts With Needle-Free Injection of Fluorouracil

Yue Wu, BM; Fei Wang, MD

Abstract Full Text

JAMA Dermatol. 2022;158(11):1330-1331. doi:10.1001/jamadermatol.2022.3318

This case report describes 2 men in their 20s who presented with warts that were treated with a needle-free injection of fluorouracil.

Treatment With Topical Sirolimus for Recurrent Lymphatic Malformation of the External Urethral Meatus

Satoru Yonekura, MD, PhD; Takaya Komori, MD, PhD; Yoshihiro Ishida, MD, PhD; et al.

Abstract Full Text

JAMA Dermatol. 2022;158(11):1331-1332. doi:10.1001/jamadermatol.2022.2793

This case report describes a 17-year-old male patient with frog spawn鈥搇ike vesicles around the urethra.

Comment & Response

Melanoma Screening

Mark Elwood, MD; Joanne Aitken, PhD; Peter Soyer, MD

Abstract Full Text

JAMA Dermatol. 2022;158(11):1332-1333. doi:10.1001/jamadermatol.2022.3907

Melanoma Screening鈥擱eply

Robert A. Swerlick, MD

Abstract Full Text

JAMA Dermatol. 2022;158(11):1333. doi:10.1001/jamadermatol.2022.3906

Correction

Updated Link and Survey Tool Added to Supplement

Abstract Full Text

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JAMA Dermatol. 2022;158(11):1333. doi:10.1001/jamadermatol.2022.4185

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Issue

November 2022, Vol 158, No. 11, Pages 1235-1333

Resurgence of Syphilis in the US鈥擴SPSTF Reaffirms Screening Guidelines

Difficult Dermatophytosis

Assessment of the Genetic Spectrum of Uncombable Hair Syndrome in a Cohort of 107 Individuals

Association of Risk of Incident Venous Thromboembolism With Atopic Dermatitis and Treatment With Janus Kinase Inhibitors: A Systematic Review and Meta-analysis

Association Between Inflammatory Bowel Disease and Both Psoriasis and Psoriatic Arthritis: A Bidirectional 2-Sample Mendelian Randomization Study

Effect of Different Itraconazole Dosing Regimens on Cure Rates, Treatment Duration, Safety, and Relapse Rates in Adult Patients With Tinea Corporis/Cruris: A Randomized Clinical Trial

Reevaluating Corticosteroid Classification Models in Patient Patch Testing

Differences in Skin Cancer Rates by Transplanted Organ Type and Patient Age After Organ Transplant in White Patients

Clinical Presentation and Outcome Differences Between Black Patients and Patients of Other Races and Ethnicities With Mycosis Fungoides and S茅zary Syndrome

Comparison of Work Relative Value Units for Outpatient Pediatric and Adult Dermatology Encounters

Credibility and Generalization of the Minimally Important Difference Concept in Dermatology: A Scoping Review

Netherton Syndrome

Peutz-Jeghers Syndrome

Generalized Nodules in an Older Adult Man

Numerous Angiomatous Lesions in an Infant

Incidence of Dermatomyositis in a Nationwide Cohort Study of US Veterans

Prevalence of Contact Allergens in Natural Skin Care Products From US Commercial Retailers

Optimized User Experience, Efficiency, and Resource Use in Online Self-Management of Atopic Dermatitis

Outcomes of COVID-19 and Vaccination in Patients With Moderate to Severe Atopic Dermatitis Treated With Tralokinumab

Treatment of Warts With Needle-Free Injection of Fluorouracil

Treatment With Topical Sirolimus for Recurrent Lymphatic Malformation of the External Urethral Meatus

Melanoma Screening

Melanoma Screening鈥擱eply

Updated Link and Survey Tool Added to Supplement

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