September 1, 2019 Issue of JAMA Dermatology

This cross-sectional study uses investment and acquisition data from financial databases, news outlets, and press releases to describe the annual trends and geographic scope of private equity鈥揵acked acquisitions of dermatology practices in the United States through May 31, 2018.

Podcast: Trends in Private Equity Acquisition of US Dermatology Practices

Association of Hidradenitis Suppurativa With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

Wei-Ti Chen, MD; Ching-Chi Chi, MD, MMS, DPhil

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JAMA Dermatol. 2019;155(9):1022-1027. doi:10.1001/jamadermatol.2019.0891

This systematic review and meta-analysis investigates the associated risk of inflammatory bowel disease in patients with hidradenitis suppurativa.

Prevalence of Advanced Liver Fibrosis in Patients With Severe Psoriasis

Catriona M. Maybury, MRCP(Derm); Heather F. Porter, PhD; Ewa Kloczko, MBBS; et al.

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JAMA Dermatol. 2019;155(9):1028-1032. doi:10.1001/jamadermatol.2019.0721

This cohort study describes the prevalence of and evaluates clinical factors associated with advanced liver fibrosis in patients with severe psoriasis.

Assessment of Antibiotic Treatment of Cellulitis and Erysipelas: A Systematic Review and Meta-analysis

Richard Brindle, DM, FRCP; O. Martin Williams, PhD, FRCP, FRCPath; Edward Barton, BM, FRCPath; et al.

Abstract Full Text

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JAMA Dermatol. 2019;155(9):1033-1040. doi:10.1001/jamadermatol.2019.0884

This systematic review and meta-analysis reports on randomized clinical trials to identify evidence-based treatment agents and methods for patients with cellulitis.

Incidence and Risk Factors of Keratinocyte Carcinoma After First Solid Organ Transplant in Ontario, Canada

Christina K. Park, MSc; Kinwah Fung, MSc; Peter C. Austin, PhD; et al.

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JAMA Dermatol. 2019;155(9):1041-1048. doi:10.1001/jamadermatol.2019.0692

This population-based cohort study examines insurance claims data and linked province-wide health databases to identify the presence or likelihood of keratinocyte carcinoma among residents of Ontario, Canada, who had undergone a solid organ transplant.

Comparison of Survival Between Patients With Single vs Multiple Primary Cutaneous Melanomas

Mary-Ann El Sharouni, MD; Arjen J. Witkamp, MD, PhD; Vigfús Sigurdsson, MD, PhD; et al.

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JAMA Dermatol. 2019;155(9):1049-1056. doi:10.1001/jamadermatol.2019.1134

This cohort study evaluates incidence, time to subsequent melanomas, difference in staging, and survival among patients with single vs multiple primary melanomas in the Netherlands.

Review

Evidence-Based Clinical Practice Guidelines for Microcystic Adnexal Carcinoma: Informed by a Systematic Review

Brandon Worley, MD, MSc; Joshua L. Owen, MD, PhD; Christopher A. Barker, MD; et al.

Abstract Full Text

JAMA Dermatol. 2019;155(9):1059-1068. doi:10.1001/jamadermatol.2019.1251

These evidence-based clinical practice guidelines informed by a systematic review provide recommendations for the care of adults with microcystic adnexal carcinoma.

Images in Dermatology

Acanthosis Nigricans Maligna

Margarida Moura Valejo Coelho, MD, MSc; Joanna Prokop, MD; Cândida Fernandes, MD

Abstract Full Text

JAMA Dermatol. 2019;155(9):1069. doi:10.1001/jamadermatol.2019.1127

This case report describes a woman in her 60s who presented with acanthosis nigricans maligna.

Nonfamilial Multiple Trichoepithelioma

Isadora Zago Miotto, MD; Ricardo Romiti, MD, PhD

Abstract Full Text

JAMA Dermatol. 2019;155(9):1070. doi:10.1001/jamadermatol.2019.1650

This case report describes a woman in her 30s who presented with multiple papules and nodules on the face that first appeared in childhood and were progressive into early adult age.

JAMA Dermatology Clinicopathological Challenge

A Firm Plaque on the Occipital Scalp

Qiong Wu, MD; Hongxiao Chen, MD; Dirk M. Elston, MD

Abstract Full Text

JAMA Dermatol. 2019;155(9):1071-1072. doi:10.1001/jamadermatol.2019.1972

A man in his 20s presented with a firm plaque on the scalp with superimposed papules. What is your diagnosis?

Painful Indurated Plaques on the Vulva

Zhen Zhang, MS; Hong Yu, MD; Zhirong Yao, MD

Abstract Full Text

JAMA Dermatol. 2019;155(9):1073-1074. doi:10.1001/jamadermatol.2019.1979

A woman in her 60s presented with a painful skin eruption on the vulva of 2 months鈥� duration and a history of rectal carcinoma with lymph node metastasis. What is your diagnosis?

Multiple Atrophic Papules and Plaques on the Trunk and Extremities of a Young Man

Kimberly A. Huerth, MD, MEd; Dominique C. Pichard, MD; Scott A. Norton, MD, MPH

Abstract Full Text

JAMA Dermatol. 2019;155(9):1075-1076. doi:10.1001/jamadermatol.2019.2239

A young man with a history of adenosine deaminase鈥揹eficient severe combined immunodeficiency presented with atrophic papules and plaques on the trunk and extremities. What is your diagnosis?

JAMA Dermatology Patient Page

Merkel Cell Carcinoma

Allison Hanlon, MD, PhD

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JAMA Dermatol. 2019;155(9):1096. doi:10.1001/jamadermatol.2019.2068

This Patient Page describes the characteristics of Merkel cell carcinoma and outlines the diagnosis and treatment of this rare skin cancer.

Research Letter

Association of the Severity of Alopecia With the Severity of Ichthyosis

Elana Putterman, BS; Theodore Zaki, BS; Leonard Milstone, MD; et al.

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JAMA Dermatol. 2019;155(9):1077-1078. doi:10.1001/jamadermatol.2019.1520

This study assesses the association between the severity of alopecia and ichthyosis disease severity and characterizes the severity of alopecia by genotype.

Topical Itraconazole for the Treatment of Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome or High-Frequency Basal Cell Carcinomas: A Phase 2, Open-Label, Placebo-Controlled Trial

Grace K. Sohn, MD; Gina P. Kwon, MD; Irene Bailey-Healy, BS; et al.

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JAMA Dermatol. 2019;155(9):1078-1080. doi:10.1001/jamadermatol.2019.1541

This phase 2, open-label, placebo-controlled examines topical itraconazole as a treatment for basal cell carcinoma.

Distinct Histopathologic Patterns of Finger Eruptions in Dermatomyositis Based on Myositis-Specific Autoantibody Profiles

Naoko Okiyama, MD, PhD; Yukie Yamaguchi, MD, PhD; Masanari Kodera, MD, PhD; et al.

Abstract Full Text

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JAMA Dermatol. 2019;155(9):1080-1082. doi:10.1001/jamadermatol.2019.1668

This histologic analysis of cutaneous manifestations of dermatomyositis examines whether skin eruptions can be histopathologically classified into myositis-specific autoantibodies-associated groups.

Observation

Morphologic Switch From Psoriasiform to Eczematous Dermatitis After Anti-IL-17 Therapy: A Case Series

Francis Yi Xing Lai, MBBS (Hons); Eleanor Higgins, MRCPI; Catherine H. Smith, FRCP; et al.

Abstract Full Text

JAMA Dermatol. 2019;155(9):1082-1084. doi:10.1001/jamadermatol.2019.1268

This case report describes a series of patients who developed eczema after being treated for psoriasis with secukinumab.

Severe Lipodystrophy Following Prolonged Subcutaneous Administration of Antisense Oligonucleotides

Anh Ly Nguyen, MD; Marie-Anne Morren, MD, PhD; Remco van Doorn, MD, PhD

Abstract Full Text

JAMA Dermatol. 2019;155(9):1084-1086. doi:10.1001/jamadermatol.2019.1404

This case report describes a severe adverse event following antisense oligonucleotide treatment for muscular dystrophy that occurred in 6 pediatric patients.