July 1, 2019 Issue of JAMA Dermatology

This cross-sectional study examines the histopathological features found with a partial biopsy of lentigo maligna tumors that are associated with an invasive component.

Localization, Morphologic Features, and Chemical Composition of Calciphylaxis-Related Skin Deposits in Patients With Calcific Uremic Arteriolopathy

Hester Colboc, MD; Philippe Moguelet, MD; Dominique Bazin, MD; et al.

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JAMA Dermatol. 2019;155(7):789-796. doi:10.1001/jamadermatol.2019.0381

This multicenter cohort study compares skin calcium deposits from adult patients with calcific uremic arteriolopathy with specimens from control participants to characterize localization, morphologic features, and composition of cutaneous calcium deposits and identify mortality-associated factors.

Comparative Overall Comorbidity Burden Among Patients With Hidradenitis Suppurativa

Sarah Reddy, BA; Andrew Strunk, MA; Amit Garg, MD

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JAMA Dermatol. 2019;155(7):797-802. doi:10.1001/jamadermatol.2019.0164

This cross-sectional study investigates the standardized overall comorbidity burden among patients with hidradenitis suppurativa and compares it with the comorbidity burden in patients with psoriasis and a control group.

Podcast: Comparative Overall Comorbidity Burden Among Patients With Hidradenitis Suppurativa

Evaluation of Lymph Node Ratio Association With Long-term Patient Survival After Surgery for Node-Positive Merkel Cell Carcinoma

Shayan Cheraghlou, BA; George O. Agogo, PhD; Michael Girardi, MD

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JAMA Dermatol. 2019;155(7):803-811. doi:10.1001/jamadermatol.2019.0267

This cohort study of 1274 patients who underwent surgery for node-positive Merkel cell carcinoma evaluates the association between lymph node ratio and long-term survival.

Characteristics of State and Federal Malpractice Litigation of Medical Liability Claims for Keratinocyte Carcinoma, 1968 to 2018

Raghav Tripathi, MPH; Harib H. Ezaldein, MD; Krithika Rajkumar, JD; et al.

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JAMA Dermatol. 2019;155(7):812-818. doi:10.1001/jamadermatol.2019.0430

This study identifies state and federal appellate medical malpractice liability cases related to keratinocyte carcinoma and assesses the factors associated with the verdicts of the cases.

Performance of the American Joint Committee on Cancer Staging Manual, 8th Edition vs the Brigham and Women鈥檚 Hospital Tumor Classification System for Cutaneous Squamous Cell Carcinoma

Emily Stamell Ruiz, MD, MPH; Pritesh S. Karia, MPH; Robert Besaw, MPH; et al.

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JAMA Dermatol. 2019;155(7):819-825. doi:10.1001/jamadermatol.2019.0032

This cohort study compares the performance of American Joint Committee on Cancer, 8th edition and the Brigham and Women鈥檚 Hospital tumor classification systems in patients diagnosed with head and neck cutaneous squamous cell carcinomas.

Association of Leukemia Cutis With Survival in Acute Myeloid Leukemia

Cynthia X. Wang, MPHS; Iskra Pusic, MD; Milan J. Anadkat, MD

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JAMA Dermatol. 2019;155(7):826-832. doi:10.1001/jamadermatol.2019.0052

This matched-cohort study of patients with acute myeloid leukemia with and without leukemia cutis assesses the association of leukemia cutis with survival.

Brief Report

Interrater Reliability of Clinical Grading Measures for Cutaneous Chronic Graft-vs-Host Disease

Adela R. Cardones, MD, MHSc; Keith M. Sullivan, MD; Cindy Green, PhD; et al.

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JAMA Dermatol. 2019;155(7):833-837. doi:10.1001/jamadermatol.2018.5459

This study evaluates the interrater agreement and reliability of skin-specific and range of motion variables of the 2014 National Institutes of Health response criteria for patients with chronic graft-vs-host disease as well as a skin sclerosis grading scale.

Assessment of Topical Corticosteroid Prescribing, Counseling, and Communication Among Dermatologists and Pharmacists

Ashley N. Millard, MD; Erik J. Stratman, MD

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JAMA Dermatol. 2019;155(7):838-843. doi:10.1001/jamadermatol.2018.5353

This survey study compares the practices of dermatologists and pharmacists in counseling patients regarding the use of topical corticosteroids.

Images in Dermatology

Vulvar Squamous Cell Carcinoma in a Patient With Vulvar Lichen Sclerosus

Lauren M. Sadowsky, BA; Bethanee J. Schlosser, MD, PhD

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JAMA Dermatol. 2019;155(7):844. doi:10.1001/jamadermatol.2019.0323

This case report describes a woman with vulvar lichen sclerosus who developed vulvar squamous cell carcinoma.

Porokeratosis Ptychotropica

Wei Liu, MD; Jia-wei Liu, MD; Dong-lai Ma, MD, PhD

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JAMA Dermatol. 2019;155(7):845. doi:10.1001/jamadermatol.2019.0602

This case report describes a man diagnosed as having porokeratosis ptychotropica after a 10-year history of pruritic eruption with hyperkeratotic plaques that had gradually become more extensive and verrucous.

JAMA Dermatology Clinicopathological Challenge

Perforating Papules in a Patient With Acute Myeloid Leukemia

Dana Malajian, MD; Sameera Husain, MD; Stephanie Gallitano, MD

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JAMA Dermatol. 2019;155(7):846-847. doi:10.1001/jamadermatol.2019.0827

A woman in her 50s with refractory acute myeloid leukemia and a history of breast cancer presented with new pulmonary nodules, elevated serum 尾-D-glucan levels, and subsequent pink papules on trunk and extremities. What is your diagnosis?

JAMA Dermatology Patient Page

Do I Have Calciphylaxis?

Jesse J. Keller, MD; Alex G. Ortega-Loayza, MD

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JAMA Dermatol. 2019;155(7):872. doi:10.1001/jamadermatol.2019.0458

This Patient Page describes the symptoms, diagnosis, and treatment of calciphylaxis, a serious, sometimes life-threatening skin disease that is difficult to treat.

Research Letter

Association of Antibiotic Resistance With Antibiotic Use for Epidermal Growth Factor Receptor Inhibitor鈥揜elated Papulopustular Eruption

Kelsey Hirotsu, MD; Timothy M. Dang, BA; Shufeng Li, MS; et al.

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JAMA Dermatol. 2019;155(7):848-850. doi:10.1001/jamadermatol.2019.0063

This medical record review investigates whether use of topical clindamycin and/or oral tetracyclines during management of epidermal growth factor receptor (EGFR) inhibitor鈥搑elated papulopustular eruption is associated with antibiotic-resistant bacterial infection.

Assessment of the Development of New Regional Dermatoses in Patients Treated for Atopic Dermatitis With Dupilumab

Gefei Alex Zhu, MD; Jennifer K. Chen, MD; Albert Chiou, MD; et al.

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JAMA Dermatol. 2019;155(7):850-852. doi:10.1001/jamadermatol.2019.0109

This cohort study describes the epidemiology, clinical features, and treatment of patients with moderate-to-severe atopic dermatitis and the association of developing new regional dermatoses with dupilumab treatment.

Knowledge, Motivations, and Practices Regarding Indoor Tanning Among Men Who Have Sex With Men in the San Francisco Bay Area

Lily Morrison, MPH; Henry F. Raymond, DrPH; Kenneth A. Katz, MD, MSc, MSCE; et al.

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JAMA Dermatol. 2019;155(7):852-854. doi:10.1001/jamadermatol.2019.0121

This study assesses knowledge, motivations, and practices regarding indoor tanning among men who have sex with men in the San Francisco Bay Area using data from the National HIV Behavioral Surveillance survey.

Variance of Basal Cell Carcinoma Subtype Reporting by Practice Setting

Deborah J. Moon, BA; Shauna Higgins, MD; Shera Feinstein, BA; et al.

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JAMA Dermatol. 2019;155(7):854-856. doi:10.1001/jamadermatol.2019.0066

This study compares the reporting of histologic subtype by the type of institution that performed the initial biopsy of histologically confirmed basal cell carcinomas.

Observation