June 1, 2019 Issue of JAMA Dermatology

This cohort study examines the use of screening in Chinese patients with leprosy before dapsone treatment for the HLA-B*13:01 allele associated with dapsone hypersensitivity syndrome.

Association of Time From Primary Diagnosis to First Distant Relapse of Metastatic Melanoma With Progression of Disease and Survival

Anaïs Vallet, MD; Bastien Oriano, MS; Laurent Mortier, MD, PhD; et al.

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JAMA Dermatol. 2019;155(6):673-678. doi:10.1001/jamadermatol.2019.0425

This cohort study examines whether progression of metastatic disease and survival are associated with the time to the first distant recurrence of melanoma.

Risk Factors for Lymphatic and Hematogenous Dissemination in Patients With Stages I to II Cutaneous Melanoma

Laura Calomarde-Rees, MD; Rosario García-Calatayud, MD; Celia Requena Caballero, MD, PhD; et al.

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JAMA Dermatol. 2019;155(6):679-687. doi:10.1001/jamadermatol.2019.0069

This cohort study identifies risk factors associated with lymphatic and hematogenous metastasis among patients with malignant stages I to II melanoma.

Risk of Melanoma Recurrence After Diagnosis of a High-Risk Primary Tumor

Lena A. von Schuckmann, MBBS, MPH; Maria Celia B. Hughes, MMedSci; Reza Ghiasvand, PhD; et al.

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JAMA Dermatol. 2019;155(6):688-693. doi:10.1001/jamadermatol.2019.0440

This cohort study examines the risk of melanoma recurrence in patients who have undergone treatment for localized melanoma at high risk of metastasis.

Incremental Health Care Expenditure of Chronic Cutaneous Ulcers in the United States

Raghav Tripathi, MPH; Konrad D. Knusel, MS; Harib H. Ezaldein, MD; et al.

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JAMA Dermatol. 2019;155(6):694-699. doi:10.1001/jamadermatol.2018.5942

This analysis of data from the US Medical Expenditure Panel Survey estimates the incremental health care costs among patients with chronic cutaneous ulcers.

Association of Ustekinumab vs TNF Inhibitor Therapy With Risk of Atrial Fibrillation and Cardiovascular Events in Patients With Psoriasis or Psoriatic Arthritis

Moa P. Lee, PharmD, MPH; Rishi J. Desai, PhD; Yinzhu Jin, MS, MPH; et al.

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JAMA Dermatol. 2019;155(6):700-707. doi:10.1001/jamadermatol.2019.0001

This cohort study compares the risk of developing atrial fibrillation or major adverse cardiovascular events associated with ustekinumab vs a tumor necrosis factor (TNF) inhibitor therapy among patients with psoriasis or psoriatic arthritis.

Association of HLA-C06:02* Status With Differential Response to Ustekinumab in Patients With Psoriasis: A Systematic Review and Meta-analysis

Lieke J. van Vugt, MD; Juul M. P. A. van den Reek, MD, PhD; Gerjon Hannink, PhD; et al.

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JAMA Dermatol. 2019;155(6):708-715. doi:10.1001/jamadermatol.2019.0098

This systematic review and meta-analysis assesses whether HLA-C*06:02 status is associated with a differential response in patients with psoriasis after 6 months of ustekinumab therapy.

Brief Report

Nonmelanoma Skin Cancer Frequency and Risk Factors in Australian Heart and Lung Transplant Recipients

Nicholas De Rosa, BMBS; Vanessa L. Paddon, MMed; Zhixin Liu, PhD; et al.

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JAMA Dermatol. 2019;155(6):716-719. doi:10.1001/jamadermatol.2018.4789

This cohort study examines the risk factors for and frequency of nonmelanoma skin cancer in Australian recipients of heart and/or lung transplant recipients over 10 years.

Analysis of Readmissions Following Hospitalization for Cellulitis in the United States

Jonathan M. Fisher, MPH; Jeremy Y. Feng, MD; Sally Y. Tan, MD, MPH; et al.

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JAMA Dermatol. 2019;155(6):720-723. doi:10.1001/jamadermatol.2018.4650

This nationally weighted cohort analysis assesses the association of hospitalization for treatment of cellulitis with readmission among patients in the US National Readmissions Database.

Assessment of Quality of Life and Treatment Outcomes of Patients With Persistent Postchemotherapy Alopecia

Azael Freites-Martinez, MD; Donald Chan, EdM; Vincent Sibaud, MD; et al.

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JAMA Dermatol. 2019;155(6):724-728. doi:10.1001/jamadermatol.2018.5071

This cohort study assesses the quality of life and treatment outcomes of patients with persistent chemotherapy-induced alopecia or endocrine therapy鈥搃nduced alopecia after chemotherapy.

JAMA Dermatology Clinical Evidence Synopsis

Evaluation of Ivermectin vs Permethrin for Treating Scabies鈥擲ummary of a Cochrane Review

Stefanie Rosumeck, MA; Alexander Nast, MD; Corinna Dressler, MSc, PhD

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JAMA Dermatol. 2019;155(6):730-732. doi:10.1001/jamadermatol.2019.0279

This clinical evidence synopsis summarizes the findings of 15 randomized clinical trials that evaluate the differences in outcome when treating scabies with ivermectin vs with permethrin.

Images in Dermatology

Capillary Malformation鈥揂rteriovenous Malformation Syndrome

Christopher D. Sibley, MD, PhD; Michele L. Ramien, MDCM

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JAMA Dermatol. 2019;155(6):733. doi:10.1001/jamadermatol.2019.0319

This case report describes a 6-year-old boy with multiple erythematous geographic patches, many with a surrounding halo of pallor.

Erosive Pustular Dermatosis of the Scalp

Irina Elena Nasturica, MD; Iuliana Busila, MD; Aimilios Lallas, MD, MSc, PhD

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JAMA Dermatol. 2019;155(6):734. doi:10.1001/jamadermatol.2018.5868

This case report describes a patient with erosive pustular dermatosis of the scalp.

JAMA Dermatology Clinicopathological Challenge

Abrupt Onset of Dysphagia, Arthritis, Joint Contractures, and Sheets of Monomorphous Waxy Papules

Traci Pawlitschek, BA; Tamar Hajar, MD; Nicole Fett, MD, MSCE

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JAMA Dermatol. 2019;155(6):737-738. doi:10.1001/jamadermatol.2018.5627

A man presents with dysphagia, arthritis, joint contractures, waxy, skin-colored papules, but normal levels of thyroid-stimulating hormone. What is your diagnosis?

Unilateral Asymptomatic Progressive Eruption of Hyperkeratotic Papules

Jaime Matarredona, MD; Javier García-Abellán, MD; Isabel Valencia Ramírez, MD

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JAMA Dermatol. 2019;155(6):739-740. doi:10.1001/jamadermatol.2019.0308

A man in his 60s with diabetes presents with a 10-year history of a slowly progressing cutaneous eruption of hyperkaratotic papules on his left leg. What is your diagnosis?

Research Letter

Influence of 鈥淣ot Relevant鈥� Responses on the Dermatology Life Quality Index (DLQI) for Patients With Psoriasis in the United States

John S. Barbieri, MD, MBA; Joel M. Gelfand, MD, MSCE

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JAMA Dermatol. 2019;155(6):743-745. doi:10.1001/jamadermatol.2018.5655

This cross-sectional study examines the overall subjective and objective evaluation of disease severity between patients with psoriasis who responded 鈥渘ot relevant鈥� vs those who responded 鈥渘ot at all鈥� on the Dermatology Life Quality Index.

Psoriasis and Risk of Mental Disorders in Denmark

Michelle Z. Leisner, MPH; Jette L. Riis, MD, PhD; Sara Schwartz, BS; et al.

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JAMA Dermatol. 2019;155(6):745-747. doi:10.1001/jamadermatol.2019.0039

This study examines the association between psoriasis and subsequent development of mental disorder using data on individuals with at least 2 hospital- or outpatient-based diagnoses of psoriasis from population-based registries covering all Danish hospitals.

Association of Psoriasis With Mental Health Disorders in South Korea

Chul Hwan Bang, MD; Jae Woong Yoon, MS; Jae Heon Chun, MS; et al.

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JAMA Dermatol. 2019;155(6):747-749. doi:10.1001/jamadermatol.2019.0315

This case-control study uses population-based data to examine the association of psoriasis with mental health disorders, and to identify trends in their rates of occurrence and times to onset after diagnosis of psoriasis.