PSORIASIS IS a life-disabling disorder in which 8% to 10% of patients aged 18 to 54 years actively contemplate suicide because of their disease.1 Treatments for moderate to severe psoriasis such as UV-B phototherapy, psoralen plus UV-A (PUVA), methotrexate, acitretin, and cyclosporine are generally used only intermittently owing to their toxic effects and/or inconvenience.2 Therefore, patients experience cycles of remission and flare, which they dislike.