A 41-year-old man with diabetes presented with a nonpruritic erythematous eruption on his penis. The eruption had been well controlled with topical corticosteroids and intermittent oral fluconazole. After 6 months, the eruption became resistant to therapy, and the patient developed dysuria without penile discharge, vague arthralgias involving his left ankle and right knee, and a new rash. On physical examination, moist, erythematous plaques without scale were present on the glans and penile shaft (Figure 1). His feet revealed multiple translucent vesicles and raised flesh-colored papules on the plantar surface bilaterally (Figure 2). He also had multiple, brown, raised plaques covering the dorsal aspect of his tongue.