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Mission Statement:JAMA Cardiology publishes exceptional original research, state-of-the-art reviews, and informative opinions that advance the science and practice of cardiology, enhance cardiovascular health, and inform health care policy. JAMA Cardiology is the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine worldwide. JAMA Cardiology focuses on all aspects of cardiovascular medicine, including epidemiology and prevention, diagnostic testing, interventional and pharmacologic therapeutics, translational research, health care policy and outcomes, and global health.

• Editor Robert O. Bonow, MD, MS

• Robert A. Harrington, MD, Stanford, California

• Marc S. Sabatine, MD, MPH, Boston, Massachusetts

• Clyde W. Yancy, MD, MSc, Chicago, Illinois

• Michael J. Pencina, PhD, Durham, North Carolina

• Adrian F. Hernandez, MD, MHS, Durham, North Carolina

• Mark D. Huffman, MD, MPH, Chicago, Illinois

• Ajay J. Kirtane, MD, SM, New York, New York

• Christopher J. O’Donnell, MD, MPH, Boston, Massachusetts

• Patrick T. O’Gara, MD, Boston, Massachusetts

• Sanjiv J. Shah, MD, Chicago, Illinois

• Daniel Lowden, Chicago, Illinois

• JAMA Cardiology, c/o Department of Medicine

• 251 E. Huron St, Galter 3-150

• Chicago, IL 60611

• Phone: (312) 926-7252

• jamacardio@jamanetwork.org

• Gregg C. Fonarow, MD, Los Angeles, California

• Elizabeth M. McNally, MD, PhD, Chicago, Illinois

• Mintu Turakhia, MD, MAS, Palo Alto, California

• Laine Elliott Thomas, PhD, Durham, North Carolina

• Eugene Braunwald, MD, Boston, Massachusetts

• Judith S. Hochman, MD, New York, New York

• Donald M. Lloyd-Jones, MD, ScM, Chicago, Illinois

• Michael S. Parmacek, MD, Philadelphia, Pennsylvania

• Daniel I. Simon, MD, Cleveland, Ohio

• Sidney C. Smith Jr, MD, Chapel Hill, North Carolina

• Douglas E. Vaughan, MD, Chicago, Illinois

• Myron L. Weisfeldt, MD, Baltimore, Maryland

• Douglas P. Zipes, MD, Indianapolis, Indiana

• Paul W. Armstrong, MD, Edmonton, Alberta, Canada

• Shinya Goto, MD, PhD, Isehara, Japan

• Peter Liu, MD, Ottawa, Ontario, Canada

• Renato D. Lopes MD, MHS, PhD, Durham, North Carolina

• Attilio Maseri, MD, Firenze, Italy

• Dorairaj Prabhakaran, MD, DM, MSc, Haryana, India

• Hugh C. Watkins, MD, PhD, Oxford, England

• Harvey D. White, MB, ChB, DSc, Auckland, New Zealand

• Sir Magdi Habib Yacoub, OM, FRS, London, England

• Offices 330 N Wabash Ave, Chicago, IL 60611

• Editor in Chief, The ÌÇÐÄvlog Howard Bauchner, MD

• Executive Editor Phil B. Fontanarosa, MD, MBA

• Executive Managing Editor Annette Flanagin

• Managing Editor Brenda Gregoline

• Deputy Managing Editor Tracy Frey

• Senior Manuscript Editors Miriam Y. Cintron, Shannon L. Sparenga

• Manuscript Editors Kevin Brown, Paul Ruich, Suzanne Walker

• Freelance Manuscript Editing Manager Diane L. Cannon

• Freelance Manuscript Editing Coordinator Connie L. Manno

• Freelance Copy Editors and Copyreaders Catherine A. Alden, Stephanie Lang Beckmeyer, Jan Clavey, Mary Coerver-Connolly, Paula Glitman, Laura King, Brandy Y. Patton, Denise M. Shaffer, Donna J. Thordsen

• Editorial Assistant Wanda Hill

• Directors Larry Bryant, Monica Mungle, Elaine Williams

• Managers and Staff Fanny L. Brown, Lenette Gardner-Gullens, Erin Kato, Peter K. Kim, Rachell Lozano, Michaela Mark, Elizabeth Zak

• Deputy Editor and Director Michael Berkwits, MD

• Director, Development and Design Michelle Kurzynski

• Staff Eric Butkus, Will English IV, Mustafa Ishaq, Daniel Morrow, Reuben Rios

• Deputy Editor and Director Ronna Henry, MD

• Staff Karen Bucher, Samantha Welker, David Song

• Deputy Editor Edward H. Livingston, MD

• CME Editor Thomas B. Cole, MD, MPH

• Director Marla A. Hall

• Staff Deanna Willis, Yolanda Davis

• Editorial Counsel Joseph P. Thornton, JD

• Staff Preeti Malani, MD, MSJ, Deanna Bellandi, Jim Michalski

• Senior Vice President and Publisher, Periodical Publications Thomas J. Easley

• Vice President, Publishing Business Operations Brian Shields

• Vice President, Publishing Production Operations Karen Adams-Taylor

• Staff Monica Smith

• Director Jeffery J. Bonistalli

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• Staff Mirna Monal

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• Managers Rick Bell, Fergus Clare, Lindsay Dawson, Ellen Gibson, Craig McCaffrey, Michael McGraw, Daniel Pickhardt, Romando Rossini, Stacy Tucker

• Staff Millette Jackson-Bates

• Directors Karl Elvin, Nancy Essex, Jaye Mize, Sean O’Donnell, Sue Sherrill

• Managers David Antos, Chris Borden, Debbie Camp, Lydia Cruz, Scott Curl, Diane Darnell, Colleen Kelly, Chris Meyer, Annemarie Neff, J.D. Neff, Sean Ohlson, Phil O'Leary, Bill Pedone, Susan Price, Binita Shah, Denise Steinhauser, Joe Wixted

• Advertising and Production Services Kim Boler, Rhonda Bailey Brown, Daniel DeGroot, Jordynn Farrar, Shawn Hansen, Euwanaha Joiner-Smith, Tiffany Jones, Joshua Lane, Cindy Rendlen, Ellen Yoshihara

• Circulation Services Julie Burton, Dexter Golden, Erin Hinchcliff, Noemi Rivera, Geneine Van Someren

• Composition and New Media Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Teri Hutchison, Mary Ann Kuranda, Joshua Lampinen, Nathan Mitre, Patricia E. Panek, La'son Diggs Sledge, George T. Thomson

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• Executive Vice President, Chief Executive Officer James L. Madara, MD

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The ÌÇÐÄvlog is a consortium of peer-reviewed print and online medical publications that includes JAMA®, JAMA Cardiology, and other specialty journals. JAMA Cardiology does not hold itself responsible for statements made by any contributor. All articles published, including opinion articles, represent the views of the authors and do not reflect the policy of the Journal, the ÌÇÐÄvlog, or the institution with which the author is affiliated, unless otherwise indicated.

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