To the Editor I read the article by Ramo et al1 titled 鈥淐ardiovascular Significance and Genetics of Epicardial and Pericardial Adiposity鈥� that was recently published in JAMA Cardiology with great interest.
The authors1 showed that the combined area of epicardial adipose tissue (EAT) and pericardial adipose tissue (PAT), named EPAT, was associated with incident cardiovascular diseases. The authors suggested this association was the result of unhealthy adiposity phenotype鈥搇ike abdominal visceral adipose tissue (VAT), rather than a local paracrine effect of EPAT.