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November 2024 - July 1883

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December 13, 2022, Vol 328, No. 22, Pages 2183-2280

This Week in JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2022;328(22):e2117244. doi:10.1001/jama.2021.17244
  • Podcast: Mindfulness Training and Exercise for Cognitive Function in Older Adults, Lifestyle Interventions in Adults With Obesity, Guidelines for Reporting Outcomes in Trial Reports, and more
Original Investigation

Effects of Mindfulness Training and Exercise on Cognitive Function in Older Adults: A Randomized Clinical Trial

Eric J. Lenze, MD; Michelle Voegtle; J. Philip Miller, AB; et al.
Abstract Full Text
free access
JAMA. 2022;328(22):2218-2229. doi:10.1001/jama.2022.21680

This randomized clinical trial examines whether mindfulness-based stress reduction, exercise, or a combination of both interventions improves cognitive function in older adults with subjective cognitive concerns.

Effect of a Remotely Delivered Self-directed Behavioral Intervention on Body Weight and Physical Health Status Among Adults With Obesity: The D-ELITE Randomized Clinical Trial

Katherine D. Hoerster, PhD, MPH; Rachel Hunter-Merrill, MA; Tanya Nguyen, BA; et al.
Abstract Full Text
free access
JAMA. 2022;328(22):2230-2241. doi:10.1001/jama.2022.21177

This clinical trial evaluates the effect of a remotely delivered and self-directed intervention for weight management vs usual care among adults in Veterans Health Administration clinics.

Effect of Diet and Exercise on Knee Pain in Patients With Osteoarthritis and Overweight or Obesity: A Randomized Clinical Trial

Stephen P. Messier, PhD; Daniel P. Beavers, PhD; Kate Queen, MD; et al.
Abstract Full Text
free access
JAMA. 2022;328(22):2242-2251. doi:10.1001/jama.2022.21893

This randomized clinical trial assesses the effect of a diet and exercise intervention vs an attention control condition on knee pain at 18-month follow-up among individuals aged 50 years or older with knee osteoarthritis and overweight or obesity.

Research Letter

Cervical Cancer Incidence Among US Women, 2001-2019

Zahed Shahmoradi, PhD; Haluk Damgacioglu, PhD; Megan A. Clarke, PhD, MHS; et al.
Abstract Full Text
free access
JAMA. 2022;328(22):2267-2269. doi:10.1001/jama.2022.17806

This study uses national cancer incidence data to evaluate calendar trends in cervical cancer incidence by age at diagnosis.

Association Between Sublingual Buprenorphine-Naloxone Exposure and Dental Disease

Mahyar Etminan, PharmD, MSc; Ramin Rezaeianzadeh, BSc; Abbas Kezouh, PhD; et al.
Abstract Full Text
free access
JAMA. 2022;328(22):2269-2271. doi:10.1001/jama.2022.17485

This study examines the association of sublingual buprenorphine/naloxone and dental adverse events using the IQVIA health claims database.

Special Communication

Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension

Nancy J. Butcher, PhD; Andrea Monsour, MPH; Emma J. Mew, MPH, MPhil; et al.
Abstract Full Text
free access has active quiz
JAMA. 2022;328(22):2252-2264. doi:10.1001/jama.2022.21022

This report, the Consolidated Standards of Reporting Trials (CONSORT)鈥揙utcomes 2022 extension, is a consensus statement on the standards for reporting outcomes in clinical trial reports and contains recommendations to be integrated with the CONSORT 2010 statement.

Viewpoint

Ending the HIV Epidemic: We Have the Tools, Do We Have the Will?

Marwan Haddad, MD, MPH; Anna K. Person, MD; Hansel E. Tookes, MD, MPH
Abstract Full Text
has audio
JAMA. 2022;328(22):2207-2208. doi:10.1001/jama.2022.22569

This Viewpoint identifies several barriers to ending the HIV epidemic and urges increasing expertise in HIV medicine in underserved areas like the South challenging legislation designed to keep students ignorant.

  • Podcast: Advances in Treatment and Prevention of HIV

Are Patient Satisfaction Instruments Harming Both Patients and Physicians?

Barak D. Richman, JD, PhD; Kevin A. Schulman, MD
Abstract Full Text
JAMA. 2022;328(22):2209-2210. doi:10.1001/jama.2022.21677

In this Viewpoint, Richman and Schulman argue that patient satisfaction surveys may not actually reflect clinical performance or assist efforts to improve patient experience and are not useful tools to measure physician performance.

A Piece of My Mind

Craniotomy, a Love Story

Christine Benvenuto, BA
Abstract Full Text
JAMA. 2022;328(22):2211-2212. doi:10.1001/jama.2022.21519

In this narrative medicine essay, a mother describes the process of diagnosis, craniotomy, and recovery her child experienced as a tribute to her child鈥檚 courage.

Editorial

The Challenge of Defining the Optimal Lifestyle Weight Loss Intervention for Real-world Settings

Rena R. Wing, PhD
Abstract Full Text
JAMA. 2022;328(22):2213-2214. doi:10.1001/jama.2022.21908

COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World

Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; et al.
Abstract Full Text
free access has audio
JAMA. 2022;328(22):2215-2216. doi:10.1001/jama.2022.20637
  • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
  • Editor's Note
    Climate Justice and Health
    Kirsten Bibbins-Domingo, PhD, MD, MAS
    JAMA
    • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
  • Editorial
    COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
    Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; Abraham Haileamlak; Jean-Marie Kayembe Ntumba; James Kigera; Laurie Laybourn-Langton; Bob Mash; Joy Muhia; Fhumulani Mavis Mulaudzi; David Ofori-Adjei; Friday Okonofua; Arash Rashidian; Maha El-Adawy; Siaka Sidibé; Abdelmadjid Snouber; James Tumwine; Mohammad Sahar Yassien; Paul Yonga; Lilia Zakhama; Chris Zielinski
    JAMA Netw Open
    • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
  • COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
    Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; Abraham Haileamlak; Jean-Marie Kayembe Ntumba; James Kigera; Laurie Laybourn-Langton; Bob Mash; Joy Muhia; Fhumulani Mavis Mulaudzi; David Ofori-Adjei; Friday Okonofua; Arash Rashidian; Maha El-Adawy; Siaka Sidibé; Abdelmadjid Snouber; James Tumwine; Mohammad Sahar Yassien; Paul Yonga; Lilia Zakhama; Chris Zielinski
    JAMA Cardiol
    • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
  • COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
    Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; Abraham Haileamlak; Jean-Marie Kayembe Ntumba; James Kigera; Laurie Laybourn-Langton; Bob Mash; Joy Muhia; Fhumulani Mavis Mulaudzi; David Ofori-Adjei; Friday Okonofua; Arash Rashidian; Maha El-Adawy; Siaka Sidibé; Abdelmadjid Snouber; James Tumwine; Mohammad Sahar Yassien; Paul Yonga; Lilia Zakhama; Chris Zielinski
    JAMA Intern Med
    • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
  • COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
    Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; Abraham Haileamlak; Jean-Marie Kayembe Ntumba; James Kigera; Laurie Laybourn-Langton; Bob Mash; Joy Muhia; Fhumulani Mavis Mulaudzi; David Ofori-Adjei; Friday Okonofua; Arash Rashidian; Maha El-Adawy; Siaka Sidibé; Abdelmadjid Snouber; James Tumwine; Mohammad Sahar Yassien; Paul Yonga; Lilia Zakhama; Chris Zielinski
    JAMA Oncol
    • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
  • The Climate Crisis Affects Us All
    Misha Rosenbach, MD; John S. Barbieri, MD, MBA
    JAMA Dermatol
    • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
JAMA Clinical Challenge

A 6-Year-Old Boy With Cough, Mucositis, and Vesiculobullous Skin Lesions

Jing Tian, MM; Teng Zhu, PhD; Yuanyuan Xiao, MD
Abstract Full Text
has active quiz
JAMA. 2022;328(22):2265-2266. doi:10.1001/jama.2022.19628

A 6-year-old boy taking no regular medications had persistent fever and cough for 15 days. Physical examination revealed eyelid swelling; vesiculobullous lesions on the palms and soles; vesicles and erosions on the face, trunk, and limbs; erosions on the lips and oral mucosa; and blisters on the anal mucosa. Laboratory testing revealed leukocytosis, and lung auscultation revealed bilateral crackles. What is the diagnosis and what would you do next?

Editor's Note

Climate Justice and Health

Kirsten Bibbins-Domingo, PhD, MD, MAS
Abstract Full Text
free access has audio
JAMA. 2022;328(22):2217. doi:10.1001/jama.2022.21104
  • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
  • Editorial
    COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
    Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; Abraham Haileamlak; Jean-Marie Kayembe Ntumba; James Kigera; Laurie Laybourn-Langton; Bob Mash; Joy Muhia; Fhumulani Mavis Mulaudzi; David Ofori-Adjei; Friday Okonofua; Arash Rashidian; Maha El-Adawy; Siaka Sidibé; Abdelmadjid Snouber; James Tumwine; Mohammad Sahar Yassien; Paul Yonga; Lilia Zakhama; Chris Zielinski
    JAMA
    • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
Medical News & Perspectives

Highlights From the American Heart Association鈥檚 Scientific Sessions 2022鈥擟OVID-19鈥檚 Ripple Effects, a Triglyceride Disappointment, Gene Editing Advances, and More

Jennifer Abbasi
Abstract Full Text
has audio
JAMA. 2022;328(22):2195-2197. doi:10.1001/jama.2022.17757

This Medical News article is an interview with conference chair Manesh Patel, MD, chief of cardiology at the Duke University School of Medicine.

  • Podcast: Highlights From the American Heart Association鈥檚 Scientific Sessions 2022
  • Podcast: November 2022 Medical News Summary

Climate Change and Health

Conflict and Climate Collide to Create an Acute Hunger Crisis for an Unprecedented 345 Million People

Howard Larkin
Abstract Full Text
has audio
JAMA. 2022;328(22):2198-2200. doi:10.1001/jama.2022.19235

This Medical News article discusses increasing global food insecurity linked to political conflict and climate change.

  • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
  • Podcast: November 2022 Medical News Summary
  • Editorial
    COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
    Lukoye Atwoli; Gregory E. Erhabor; Aiah A. Gbakima; Abraham Haileamlak; Jean-Marie Kayembe Ntumba; James Kigera; Laurie Laybourn-Langton; Bob Mash; Joy Muhia; Fhumulani Mavis Mulaudzi; David Ofori-Adjei; Friday Okonofua; Arash Rashidian; Maha El-Adawy; Siaka Sidibé; Abdelmadjid Snouber; James Tumwine; Mohammad Sahar Yassien; Paul Yonga; Lilia Zakhama; Chris Zielinski
    JAMA
    • Podcast: COP27 Climate Change Conference鈥擴rgent Action Needed for Africa and the World
News From the Centers for Disease Control and Prevention

Early Treatment Recommended for Patients With HIV and Monkeypox

Bridget M. Kuehn, MSJ
Abstract Full Text
free access
JAMA. 2022;328(22):2203. doi:10.1001/jama.2022.20035

Inequity in Paxlovid Prescribing

Bridget M. Kuehn, MSJ
Abstract Full Text
free access
JAMA. 2022;328(22):2203-2204. doi:10.1001/jama.2022.20036
Biotech Innovations

鈥淥ff-the-Shelf鈥� CAR T-Cell Therapy Tested in Pediatric B-Cell Leukemia

Howard Larkin
Abstract Full Text
JAMA. 2022;328(22):2201. doi:10.1001/jama.2022.20033

Investigational RSV Vaccine Given During Pregnancy Protects Newborns

Howard Larkin
Abstract Full Text
JAMA. 2022;328(22):2201. doi:10.1001/jama.2022.20032

Researchers Use Plasmid Gene Editing to Personalize Solid Tumor T-Cell Therapy

Howard Larkin
Abstract Full Text
JAMA. 2022;328(22):2201-2202. doi:10.1001/jama.2022.20034
Poetry and Medicine

Miscarriage

Sarah N. Cross, MD
Abstract Full Text
JAMA. 2022;328(22):2275. doi:10.1001/jama.2022.21174
JAMA Revisited

Smallpox: A Test of Civilization

Abstract Full Text
JAMA. 2022;328(22):2276. doi:10.1001/jama.2021.17245
JAMA Patient Page

What Is an Abdominal Aortic Aneurysm?

Jayson R. Baman, MD; Mark K. Eskandari, MD
Abstract Full Text
free access
JAMA. 2022;328(22):2280. doi:10.1001/jama.2022.18638

This JAMA Patient Page describes abdominal aortic aneurysms and their symptoms, risk factors, diagnosis, and treatment.

Comment & Response

Trends in Adverse Event Rates Among Hospitalized Patients From 2010 to 2019

Ruth Ann Dorrill, MPA; Amy Ashcraft, MPA; Julie Taitsman, MD, JD
Abstract Full Text
JAMA. 2022;328(22):2271-2272. doi:10.1001/jama.2022.18169

Trends in Adverse Event Rates Among Hospitalized Patients From 2010 to 2019鈥擱eply

Noel Eldridge, MS; Mark Metersky, MD; Erin Grace, MHA
Abstract Full Text
JAMA. 2022;328(22):2272-2273. doi:10.1001/jama.2022.18172

Dual Antiplatelet Therapy With Ticagrelor and Vein Graft Failure After Coronary Artery Bypass Graft Surgery

Bing-Yan Zeng, MD; Ping-Tao Tseng, MD, PhD; Chih-Sung Liang, MD
Abstract Full Text
JAMA. 2022;328(22):2273. doi:10.1001/jama.2022.18751

Dual Antiplatelet Therapy With Ticagrelor and Vein Graft Failure After Coronary Artery Bypass Graft Surgery鈥擱eply

Sigrid Sandner, MD; Björn Redfors, MD, PhD; Mario Gaudino, MD, PhD
Abstract Full Text
JAMA. 2022;328(22):2273-2274. doi:10.1001/jama.2022.18756
Correction

Error in Table

Abstract Full Text
free access
JAMA. 2022;328(22):2274. doi:10.1001/jama.2022.21078

Incorrect Data

Abstract Full Text
free access
JAMA. 2022;328(22):2274. doi:10.1001/jama.2022.21727
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2022;328(22):2183-2184. doi:10.1001/jama.2021.17242

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