November 1, 2022 Issue of JAMA

November 1, 2022, Vol 328, No. 17, Pages 1665-1780 | Health Care Access and Reproductive Rights

This Week in JAMA

Audio Highlights

Abstract Full Text

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JAMA. 2022;328(17):e2117194. doi:10.1001/jama.2021.17194

Podcast: Health Care Access and Reproductive Rights: Research, Viewpoints, Editorials, and more.

Original Investigation

Associations of Unintended Pregnancy With Maternal and Infant Health Outcomes: A Systematic Review and Meta-analysis

Heidi D. Nelson, MD, MPH; Blair G. Darney, PhD; Katherine Ahrens, PhD; et al.

Abstract Full Text

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JAMA. 2022;328(17):1714-1729. doi:10.1001/jama.2022.19097

This systematic review and meta-analysis uses online databases and manual review of reference lists to evaluate associations of unintended pregnancy with maternal and infant health outcomes during pregnancy and post partum in the US.

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

Viral Shedding 1 Year Following First-Episode Genital HSV-1 Infection

Christine Johnston, MD; Amalia Magaret, PhD; Hyunju Son, MSc; et al.

Abstract Full Text

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JAMA. 2022;328(17):1730-1739. doi:10.1001/jama.2022.19061

This study examines genital HSV-1 transmission and oral and genital viral shedding patterns among persons with first-episode genital HSV-1 infection.

Editorial
Shedding Patterns of Genital Herpes Simplex Virus Infections
Richard J. Whitley, MD; Edward W. Hook III, MD

JAMA
Reducing HSV-2 Morbidity and Mortality: Routine Serologic Screening Still Not the Best Answer
Mark D. Pearlman, MD

JAMA
- Podcast: USPSTF Recommendation: Serologic Screening for Genital Herpes Infection

Research Letter

Adverse Maternal and Delivery Outcomes in Children and Very Young (Age 鈮�13 Years) US Adolescents Compared With Older Adolescents and Adults

Beth L. Pineles, MD, PhD; Anthony D. Harris, MD, MPH; Katherine E. Goodman, JD, PhD

Abstract Full Text

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JAMA. 2022;328(17):1766-1768. doi:10.1001/jama.2022.18340

This study uses a US claims database to compare morbidity and delivery outcomes among pregnant 10- to 13-year-olds vs 14- to 17-year-olds and 18- to 19-year-olds.

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

Requests for Self-managed Medication Abortion Provided Using Online Telemedicine in 30 US States Before and After the Dobbs v Jackson Women鈥檚 Health Organization Decision

Abigail R. A. Aiken, PhD; Jennifer E. Starling, PhD; James G. Scott, PhD; et al.

Abstract Full Text

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JAMA. 2022;328(17):1768-1770. doi:10.1001/jama.2022.18865

This study assesses changes in online telemedicine requests to self-manage abortions with medications before vs after the Dobbs v Jackson Women鈥檚 Health Organization Supreme Court decision overturning Roe v Wade.

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

US Preventive Services Task Force

Recommendation Statement

Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force

Abstract Full Text

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JAMA. 2022;328(17):1740-1746. doi:10.1001/jama.2022.18625

This 2022 Recommendation Statement from the US Preventive Services Task Force recommends against the use of combined estrogen and progestin for the primary prevention of chronic conditions in postmenopausal persons (D recommendation) and against the use of estrogen alone for the primary prevention of chronic conditions in postmenopausal persons who have had a hysterectomy. (D recommendation).

Podcast: USPSTF Recommendation: Hormone Therapy for Prevention of Postmenopausal Chronic Conditions

Editorial
Menopausal Hormone Therapy for Prevention of Chronic Conditions: When Is Enough, Enough?
Alison J. Huang, MD, MAS; Deborah Grady, MD, MPH

JAMA

Evidence Report

Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Gerald Gartlehner, MD, MPH; Sheila V. Patel, PhD; Shivani Reddy, MD, MS; et al.

Abstract Full Text

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JAMA. 2022;328(17):1747-1765. doi:10.1001/jama.2022.18324

This systematic review to support the 2022 US Preventive Services Task Force Recommendation Statement on hormone therapy for primary prevention of chronic conditions summarizes published evidence on the benefits and harms of estrogen only or estrogen plus progestin for the primary prevention of chronic conditions in generally healthy perimenopausal and postmenopausal persons eligible for hormone therapy.

Podcast: USPSTF Recommendation: Hormone Therapy for Prevention of Postmenopausal Chronic Conditions

Editorial
Menopausal Hormone Therapy for Prevention of Chronic Conditions: When Is Enough, Enough?
Alison J. Huang, MD, MAS; Deborah Grady, MD, MPH

JAMA

Viewpoint

Advancing Birth Equity in a Post-Dobbs US

Joia Crear-Perry, MD; Asha Hassan, MPH; Sara Daniel, MPH

Abstract Full Text

JAMA. 2022;328(17):1689-1690. doi:10.1001/jama.2022.19468

This Viewpoint discusses the US Supreme Court鈥檚 decision in Dobbs v Jackson Women鈥檚 Health Organization, describes how that decision threatens birth equity for some racial and social groups, and suggests a reproductive justice approach to address racial and social inequalities and ensure reproductive freedom and autonomy for all people.

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

The Challenge of Emergency Abortion Care Following the Dobbs Ruling

Andrea MacDonald, MD; Hayley B. Gershengorn, MD; Deepshikha Charan Ashana, MD, MBA, MS

Abstract Full Text

has multimedia has audio

JAMA. 2022;328(17):1691-1692. doi:10.1001/jama.2022.17197

This Viewpoint discusses how limited or blocked access to legal abortion will affect the provision of emergency and critical care, including negative effects on patient health, legal intrusion into the patient-physician decision-making process, and concerns about legal jeopardy.

Video: Medical Indications for Abortion

Podcast: The Future of Ob-Gyn Training in the US Post-Dobbs

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

Self-managed Abortion in the US

Daniel Grossman, MD; Nisha Verma, MD, MPH

Abstract Full Text

JAMA. 2022;328(17):1693-1694. doi:10.1001/jama.2022.19057

This Viewpoint details how clinicians can treat patients who have self-managed an abortion without putting the patient at risk for criminalization.

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

Legal Risks and Ethical Dilemmas for Clinicians in the Aftermath of Dobbs

Rebecca B. Reingold, JD; Lawrence O. Gostin, JD; Michele Bratcher Goodwin, JD, LLM, SJD

Abstract Full Text

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JAMA. 2022;328(17):1695-1696. doi:10.1001/jama.2022.18453

This Viewpoint discusses the ways in which the Supreme Court鈥檚 ruling in Dobbs v Jackson Women鈥檚 Health Organization, which triggered abortion bans or restrictions in half of states, presents serious legal risks to clinicians and major ethical dilemmas.

Video: Medical Indications for Abortion

Podcast: The Future of Ob-Gyn Training in the US Post-Dobbs
Podcast: Clinical and Legal Dilemmas of Providing Reproductive Health Care After the Dobbs Decision

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

Implications of the Dobbs Decision for Medical Education: Inadequate Training and Moral Distress

Biftu Mengesha, MD, MAS; Nikki Zite, MD, MPH; Jody Steinauer, MD, PhD

Abstract Full Text

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JAMA. 2022;328(17):1697-1698. doi:10.1001/jama.2022.19544

This Viewpoint discusses how states鈥� restrictions on abortion will affect medical students鈥� training in providing reproductive health care and also create moral distress by being forced to provide care that may harm patients.

Video: Medical Indications for Abortion

Podcast: The Future of Ob-Gyn Training in the US Post-Dobbs

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

The Shift From Criminalization to Legalization of Abortion in Argentina

Mariana Romero, MD, MSc; Agustina Ramón Michel, JD

Abstract Full Text

JAMA. 2022;328(17):1699-1700. doi:10.1001/jama.2022.18971

This Viewpoint discusses passage and implementation of Law 27.610, which legalized abortion in Argentina under certain circumstances, and examines the ongoing clinical issues and legal challenges to the law.

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

Confronting the Medical Community鈥檚 Complicity in Marginalizing Abortion Care

Sonya Borrero, MD, MS; Mehret Birru Talabi, MD, PhD; Christine Dehlendorf, MD, MAS

Abstract Full Text

JAMA. 2022;328(17):1701-1702. doi:10.1001/jama.2022.18328

This Viewpoint discusses the exclusion of abortion care from many established medical sources (such as hospitals) and from coverage by many major payers and how the health care system should legitimize and ensure clinician training in safe abortion care.

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

Interoperability in a Post-Roe Era: Sustaining Progress While Protecting Reproductive Health Information

Daniel M. Walker, PhD, MPH; Sharona Hoffman, JD, LLM, SJD; Julia Adler-Milstein, PhD

Abstract Full Text

JAMA. 2022;328(17):1703-1704. doi:10.1001/jama.2022.17204

This Viewpoint proposes a solution to better safeguard reproductive health information in patient records that are now more complete owing to the interoperability of health information exchange networks.

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

A Piece of My Mind

Ask Me Anything

Caroline Wellbery, MD, PhD

Abstract Full Text

JAMA. 2022;328(17):1705-1706. doi:10.1001/jama.2022.19456

In this narrative medicine essay, a retired family physician considers whether it is appropriate to offer medical advice to friends and family and ultimately decides that these consults are fine as long as the individual talks with their physician.

Editorial

Health Care Access and Reproductive Rights

Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

Abstract Full Text

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JAMA. 2022;328(17):1707-1709. doi:10.1001/jama.2022.19172

Editorial
Looking Back and Moving Forward鈥�JAMA 2022 Year in Review
Kirsten Bibbins-Domingo, PhD, MD, MAS; Annette Flanagin, MA, RN; Stacy L. Christiansen, MA; Greg Curfman, MD

JAMA

Shedding Patterns of Genital Herpes Simplex Virus Infections

Richard J. Whitley, MD; Edward W. Hook III, MD

Abstract Full Text

free access

JAMA. 2022;328(17):1710-1711. doi:10.1001/jama.2022.18930

Menopausal Hormone Therapy for Prevention of Chronic Conditions: When Is Enough, Enough?

Alison J. Huang, MD, MAS; Deborah Grady, MD, MPH

Abstract Full Text

JAMA. 2022;328(17):1712-1713. doi:10.1001/jama.2022.19098

Medical News & Perspectives

Dobbs Decision Threatens Full Breadth of Ob-Gyn Training

Rachel Rabkin Peachman

Abstract Full Text

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JAMA. 2022;328(17):1668-1670. doi:10.1001/jama.2022.13662

This Medical News article discusses how the overturning of Roe v Wade will change training for future obstetrician-gynecologists in states where abortion is banned or severely restricted.

Video: Medical Indications for Abortion

Podcast: The Future of Ob-Gyn Training in the US Post-Dobbs
Podcast: October 2022 Medical News Summary

Threats to Evidence-Based Care With Teratogenic Medications in States With Abortion Restrictions

Rita Rubin, MA

Abstract Full Text

has multimedia has audio

JAMA. 2022;328(17):1671-1673. doi:10.1001/jama.2022.11489

This Medical News article discusses how abortion bans could affect patients for whom teratogenic drugs are the standard of care.

Video: Medical Indications for Abortion

Podcast: The Future of Ob-Gyn Training in the US Post-Dobbs
Podcast: October 2022 Medical News Summary

Treating Cancer in Pregnant Patients After Roe v Wade Overturned

Melissa Suran, PhD, MSJ

Abstract Full Text

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JAMA. 2022;328(17):1674-1676. doi:10.1001/jama.2022.13668

This medical news feature discusses the challenges of treating pregnant patients diagnosed with cancer following the reversal of Roe v Wade.

Video: Medical Indications for Abortion

Podcast: The Future of Ob-Gyn Training in the US Post-Dobbs
Podcast: October 2022 Medical News Summary

News From the 糖心vlog

Monkeypox Neurologic Complications May Be Similar to Smallpox

Anita Slomski

Abstract Full Text

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JAMA. 2022;328(17):1677. doi:10.1001/jama.2022.18441

Almost All 鈥淣atural鈥� Skin Care Products Contain Contact Allergens

Anita Slomski

Abstract Full Text

JAMA. 2022;328(17):1677. doi:10.1001/jama.2022.18440

Perioperative Gabapentin Linked to Harms for Older Adults

Anita Slomski

Abstract Full Text

JAMA. 2022;328(17):1677-1678. doi:10.1001/jama.2022.18442

Earlier Bedtimes Help Kids Get More Sleep

Anita Slomski

Abstract Full Text

JAMA. 2022;328(17):1678. doi:10.1001/jama.2022.18443

News From the Food and Drug Administration

Selpercatinib Receives Regular Approval for Non鈥揝mall Cell Lung Cancer

Howard D. Larkin

Abstract Full Text

JAMA. 2022;328(17):1679. doi:10.1001/jama.2022.18445

Cybersecurity Risk for Medtronic Insulin Pump

Howard D. Larkin

Abstract Full Text

JAMA. 2022;328(17):1679. doi:10.1001/jama.2022.18444

New Guidance Aims to Improve Community Access to Naloxone

Howard D. Larkin

Abstract Full Text

JAMA. 2022;328(17):1679. doi:10.1001/jama.2022.18446

Autologous Gene Therapy Approved for Childhood CALD

Howard D. Larkin

Abstract Full Text

JAMA. 2022;328(17):1679-1680. doi:10.1001/jama.2022.19800

New Research Partnership for ALS, Rare Neurodegenerative Diseases

Howard D. Larkin

Abstract Full Text

JAMA. 2022;328(17):1680. doi:10.1001/jama.2022.19801

Poetry and Medicine

Being Receptive

Michael Wynn, DO

Abstract Full Text

JAMA. 2022;328(17):1773. doi:10.1001/jama.2022.18772

JAMA Revisited

Experimental Epidemiology

Abstract Full Text

JAMA. 2022;328(17):1774. doi:10.1001/jama.2021.17195

JAMA Patient Page

Medication Abortion

Rebecca H. Cohen, MD, MPH; Stephanie B. Teal, MD, MPH

Abstract Full Text

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JAMA. 2022;328(17):1779. doi:10.1001/jama.2022.14805

This JAMA Patient Page describes medication abortion and its risks and effectiveness.

Podcast: Medication Abortion Using Mifepristone and Misoprostol

Editorial
Health Care Access and Reproductive Rights
Linda Brubaker, MD, MS; Kirsten Bibbins-Domingo, MD, PhD, MAS

JAMA

Menopausal Hormone Therapy for Prevention of Chronic Conditions

Jill Jin, MD, MPH

Abstract Full Text

free access has audio

JAMA. 2022;328(17):1780. doi:10.1001/jama.2022.19855

This JAMA Patient Page summarizes the US Preventive Services Task Force鈥檚 recommendations on use of hormone therapy for prevention of chronic conditions in postmenopausal individuals.

Podcast: USPSTF Recommendation: Hormone Therapy for Prevention of Postmenopausal Chronic Conditions
Podcast: Menopausal Hormone Therapy for Prevention of Chronic Conditions