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November 2024 - July 1883

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May 17, 2022, Vol 327, No. 19, Pages 1849-1936

This Week in JAMA

Audio Highlights

Abstract Full Text
free access online only has audio
JAMA. 2022;327(19):e2116973. doi:10.1001/jama.2021.16973
Original Investigation

Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial

Abstract Full Text
free access has multimedia
JAMA. 2022;327(19):1875-1887. doi:10.1001/jama.2022.5776

This randomized clinical trial assesses whether transcatheter aortic valve implantation (TAVI) is noninferior to surgical aortic valve replacement in patients at moderately increased operative risk.

Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2022;327(19):1888-1898. doi:10.1001/jama.2022.5368

This randomized clinical trial examines the effect of oral methylprednisolone on the risk of major kidney outcomes, including 40% decline in eGFR, kidney failure (dialysis, transplant), or death due to kidney disease, and adverse effects in individuals with IgA nephropathy and proteinuria.

Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial

Abstract Full Text
free access
JAMA. 2022;327(19):1899-1909. doi:10.1001/jama.2022.4798

This multicenter clinical trial investigated potential benefits of early vs standard tracheostomy in patients with severe stroke receiving mechanical ventilation.

Research Letter

Association Between SARS-CoV-2 Viral Load in Wastewater and Reported Cases, Hospitalizations, and Vaccinations in Milan, March 2020 to November 2021

Abstract Full Text
free access has active quiz
JAMA. 2022;327(19):1922-1924. doi:10.1001/jama.2022.4908

This study evaluates the association between SARS-CoV-2 load in urban wastewater and surveillance indicators of infection prevalence and severity in Milan, Italy.

Prediabetes and Diabetes Screening Eligibility and Detection in US Adults After Changes to US Preventive Services Task Force and American Diabetes Association Recommendations

Abstract Full Text
free access
JAMA. 2022;327(19):1924-1925. doi:10.1001/jama.2022.5185

This cross-sectional study using NHANES data assesses the proportion of asymptomatic US adults eligible for screening based on new vs current US Preventive Services Task Force and American Diabetes Association screening guidelines, overall and among those with prediabetes or undiagnosed diabetes.

Special Communication

Ethical Considerations for the Inclusion of Patient-Reported Outcomes in Clinical Research: The PRO Ethics Guidelines

Abstract Full Text
free access has active quiz has audio
JAMA. 2022;327(19):1910-1919. doi:10.1001/jama.2022.6421

These international, consensus-based, patient-reported outcomes (PRO)鈥搒pecific guidelines aim to lay out the ethical considerations that researchers, research ethics committees, and funders should take into account when conducting or reviewing PRO clinical research.

Viewpoint

COVID-19 Vaccination鈥擝ecoming Part of the New Normal

Abstract Full Text
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JAMA. 2022;327(19):1863-1864. doi:10.1001/jama.2022.7469

In this Viewpoint, authors from the FDA discuss how COVID-19 vaccination is an integral part of establishing a new normal, now that SARS-CoV-2, the virus that causes COVID-19, will likely circulate worldwide for the foreseeable future.

Getting Serious About Producing Health: The Ten Teams Challenge

Abstract Full Text
JAMA. 2022;327(19):1865-1866. doi:10.1001/jama.2022.6921

In this Viewpoint, Berwick proposes the 鈥淭en Teams鈥 approach to improving social influences on health, with hospitals and health systems working to improve health care coverage, food insecurity, housing, education, and related factors.

Firearm Homicide and Suicide During the COVID-19 Pandemic: Implications for Clinicians and Health Care Systems

Abstract Full Text
free access
JAMA. 2022;327(19):1867-1868. doi:10.1001/jama.2022.6924

This Viewpoint discusses the COVID-19 pandemic, community鈥搇aw enforcement tensions, and social and structural factors that have potentially contributed to increased risks for homicide and suicide in the US.

A Piece of My Mind

The Pandemic Determinants of Health

Abstract Full Text
free access
JAMA. 2022;327(19):1869. doi:10.1001/jama.2022.7204

In this narrative medicine essay, a primary care physician relates the complexity of routine patient visits that have been distrupted by the 2-year COVID-19 pandemic and shares how she has adapted her medical advice to addressing the stress and sorrow patients experience.

Editorial

Treatment of Aortic Stenosis With Transcatheter Aortic Valve Implantation

Abstract Full Text
has multimedia
JAMA. 2022;327(19):1870-1871. doi:10.1001/jama.2022.5424

Oral Glucocorticoids for IgA Nephropathy

Abstract Full Text
JAMA. 2022;327(19):1872-1874. doi:10.1001/jama.2022.4638
JAMA Clinical Challenge

Ulcerated Plaques on the Scalp and Dorsal Hands of an Older Man

Abstract Full Text
has active quiz
JAMA. 2022;327(19):1920-1921. doi:10.1001/jama.2022.6315

A man in his 60s had 4 months of fatigue, night sweats, weight loss, and tender, nonfluctuant plaques on his scalp and hands, with overlying hemorrhagic crust and necrosis on an erythematous indurated base; clinical evaluation showed pancytopenia, and an acute deep vein thrombosis involving the left common and external iliac veins and distal inferior vena cava. What is the diagnosis and what would you do next?

Medical News & Perspectives

The COVID-19 Pandemic Rages on for People Who Are Immunocompromised

Abstract Full Text
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JAMA. 2022;327(19):1853-1855. doi:10.1001/jama.2022.7281

This Medical News feature discusses the status of people with compromised immune systems more than 2 years into the pandemic.

Resolving Payment Issues Is Essential to Realize Telehealth鈥檚 Promise

Abstract Full Text
JAMA. 2022;327(19):1856-1858. doi:10.1001/jama.2022.7460

This Medical News article discusses telehealth payment issues that extend beyond the COVID-19 public health emergency, which is set to expire in mid-July.

News From the Food and Drug Administration

First Breathalyzer Test to Diagnose COVID-19

Abstract Full Text
free access
JAMA. 2022;327(19):1860. doi:10.1001/jama.2022.7700

More Diversity in Clinical Trials

Abstract Full Text
JAMA. 2022;327(19):1860. doi:10.1001/jama.2022.7172

Websites Selling Controlled Drugs Without a Prescription

Abstract Full Text
JAMA. 2022;327(19):1860. doi:10.1001/jama.2022.7701
Global Health

WHO Program May Eliminate Active Trachoma鈥檚 Blindness Risk by 2030

Abstract Full Text
JAMA. 2022;327(19):1859. doi:10.1001/jama.2022.7383

One-third of English GPs Plan to Quit Within 5 Years

Abstract Full Text
JAMA. 2022;327(19):1859. doi:10.1001/jama.2022.7732

Ukraine War Could Push an Additional 47 Million Into Acute Hunger

Abstract Full Text
JAMA. 2022;327(19):1859. doi:10.1001/jama.2022.7733
The Arts and Medicine

Asclepius Revisited鈥擜ncient Myth and 21st-Century Psychedelic Medicine

Abstract Full Text
JAMA. 2022;327(19):1851-1852. doi:10.1001/jama.2022.6528

This Arts and Medicine essay reviews how 21st-century evidence-based approaches to the use of psychedelic medicine replicate the ancient practices of Asclepian medicine.

Poetry and Medicine

Scenes From the Children鈥檚 Hospital

Abstract Full Text
JAMA. 2022;327(19):1931. doi:10.1001/jama.2022.3867
JAMA Revisited
JAMA Patient Page

Psoriasis

Abstract Full Text
free access
JAMA. 2022;327(19):1936. doi:10.1001/jama.2022.5270

This JAMA Patient Page describes the skin condition psoriasis and its diagnosis, risk factors, and treatment.

Comment & Response

Rapid Antigen Tests for SARS-CoV-2

Abstract Full Text
JAMA. 2022;327(19):1925-1926. doi:10.1001/jama.2022.4466

Rapid Antigen Tests for SARS-CoV-2鈥擱eply

Abstract Full Text
JAMA. 2022;327(19):1926. doi:10.1001/jama.2022.4469

Penetrance of Deleterious Clinical Variants

Abstract Full Text
JAMA. 2022;327(19):1926-1927. doi:10.1001/jama.2022.4631

Penetrance of Deleterious Clinical Variants鈥擱eply

Abstract Full Text
JAMA. 2022;327(19):1927. doi:10.1001/jama.2022.4634

Moderate Hypothermia vs Normothermia and 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial ECMO

Abstract Full Text
JAMA. 2022;327(19):1927-1928. doi:10.1001/jama.2022.5043

Moderate Hypothermia vs Normothermia and 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial ECMO

Abstract Full Text
JAMA. 2022;327(19):1928. doi:10.1001/jama.2022.5040

Moderate Hypothermia vs Normothermia and 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial ECMO鈥擱eply

Abstract Full Text
JAMA. 2022;327(19):1928-1929. doi:10.1001/jama.2022.5046
Correction

Incorrect y-Axis and Panel Labels in Figure

Abstract Full Text
free access
JAMA. 2022;327(19):1929. doi:10.1001/jama.2022.7048
JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2022;327(19):1849-1850. doi:10.1001/jama.2021.16971
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