May 3, 2022 Issue of JAMA

May 3, 2022, Vol 327, No. 17, Pages 1637-1716

This Week in JAMA

Audio Highlights

Abstract Full Text

free access online only has audio

JAMA. 2022;327(17):e2116953. doi:10.1001/jama.2021.16953

Podcast: Self-monitoring Blood Pressure During Pregnancy, Treating Elevated Lipoprotein(a) Levels, Diagnosis and Management of Lumbar Spinal Stenosis, and more

Original Investigation

Effect of Self-monitoring of Blood Pressure on Diagnosis of Hypertension During Higher-Risk Pregnancy: The BUMP 1 Randomized Clinical Trial

Katherine L. Tucker, PhD; Sam Mort, PGCert; Ly-Mee Yu, DPhil; et al.

Abstract Full Text

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JAMA. 2022;327(17):1656-1665. doi:10.1001/jama.2022.4712

This randomized clinical trial compares the efficacy of self-monitoring of blood pressure with telemonitoring vs usual antenatal care in detecting hypertension among pregnant individuals at higher risk of preeclampsia.

Podcast: Effect of Self-monitoring of Blood Pressure on Detection and Assessment of Hypertension During Higher-Risk Pregnancy: The BUMP 1 and BUMP 2 Trials

Editorial
Self-monitoring of Blood Pressure During Pregnancy
Malavika Prabhu, MD; Line Malha, MD; Laura E. Riley, MD

JAMA
- Podcast: Effect of Self-monitoring of Blood Pressure on Detection and Assessment of Hypertension During Higher-Risk Pregnancy: The BUMP 1 and BUMP 2 Trials

Effect of Self-monitoring of Blood Pressure on Blood Pressure Control in Pregnant Individuals With Chronic or Gestational Hypertension: The BUMP 2 Randomized Clinical Trial

Lucy C. Chappell, MB BChir, PhD; Katherine L. Tucker, PhD; Ushma Galal, MSc; et al.

Abstract Full Text

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JAMA. 2022;327(17):1666-1678. doi:10.1001/jama.2022.4726

This clinical trial compares the effectiveness of blood pressure (BP) self-monitoring vs usual care alone on BP control and other related maternal and infant outcomes in pregnant individuals with hypertension.

Podcast: Effect of Self-monitoring of Blood Pressure on Detection and Assessment of Hypertension During Higher-Risk Pregnancy: The BUMP 1 and BUMP 2 Trials

Editorial
Self-monitoring of Blood Pressure During Pregnancy
Malavika Prabhu, MD; Line Malha, MD; Laura E. Riley, MD

JAMA
- Podcast: Effect of Self-monitoring of Blood Pressure on Detection and Assessment of Hypertension During Higher-Risk Pregnancy: The BUMP 1 and BUMP 2 Trials

Preliminary Communication

Single Ascending Dose Study of a Short Interfering RNA Targeting Lipoprotein(a) Production in Individuals With Elevated Plasma Lipoprotein(a) Levels

Steven E. Nissen, MD; Kathy Wolski, MPH; Craig Balog, BS; et al.

Abstract Full Text

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JAMA. 2022;327(17):1679-1687. doi:10.1001/jama.2022.5050

This phase 1 study evaluated the safety and tolerability of 4 different doses of a short interfering RNA designed to reduce hepatic production of apolipoprotein(a) and assessed associated changes in plasma concentrations of lipoprotein(a), compared with placebo, among individuals with elevated lipoprotein(a) levels and no known cardiovascular disease.

Podcast: Highlights From the American College of Cardiology鈥檚 Scientific Sessions: New Heart Failure Management Guidelines and more

Editorial
The Potential Clinical Benefit of Lowering Lipoprotein(a)
Brian A. Ference, MD, MPhil, MSc

JAMA
- Podcast: Highlights From the American College of Cardiology鈥檚 Scientific Sessions: New Heart Failure Management Guidelines and more

Research Letter

Alcohol-Related Deaths During the COVID-19 Pandemic

Aaron M. White, PhD; I-Jen P. Castle, PhD; Patricia A. Powell, PhD; et al.

Abstract Full Text

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JAMA. 2022;327(17):1704-1706. doi:10.1001/jama.2022.4308

This study uses mortality data from the National Center for Health Statistics to assess whether alcohol-related deaths increased during the COVID-19 pandemic.

Viewpoint

Implementation of a Standardized Clinical Definition of Opioid Withdrawal in the Neonate: Challenges and Opportunities

Shahla M. Jilani, MD; Hendrée E. Jones, PhD; Jonathan M. Davis, MD

Abstract Full Text

JAMA. 2022;327(17):1643-1644. doi:10.1001/jama.2022.5406

This Viewpoint discusses increases in opioid use disorder among pregnant people during the US opioid crisis and recommendations to define, diagnose, and treat neonatal abstinence syndrome and neonatal opioid withdrawal syndrome.

American Board of Medical Specialties and New Standards for Continuing Certification

Richard E. Hawkins, MD; Greg Ogrinc, MD, MS; Susan M. Ramin, MD

Abstract Full Text

JAMA. 2022;327(17):1645-1646. doi:10.1001/jama.2022.6053

This Viewpoint discusses the ways in which the updated Standards for Continuing Certification reflect foundational changes in how the American Board of Medical Specialties and the member boards perform professional self-regulation, including the intent of the Standards to bring value to both the public and the profession.

Risks to the 340B Drug Pricing Program Related to Manufacturer Restrictions on Drug Availability

Ryan P. Knox, JD; Aaron S. Kesselheim, MD, JD, MPH; Ameet Sarpatwari, PhD, JD

Abstract Full Text

JAMA. 2022;327(17):1647-1648. doi:10.1001/jama.2022.5959

This Viewpoint documents the history, value, and success of the 340B Pricing Program, which is under threat from pharmaceutical corporations鈥� withdrawal and from a pending Supreme Court decision and offers 2 legislative fixes to address the concerns raised by the pharmaceutical companies.

A Piece of My Mind

Unmasked Facies

Emily Anne Ferenczi, BMBCh, PhD

Abstract Full Text

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JAMA. 2022;327(17):1649-1650. doi:10.1001/jama.2022.6307

In this narrative medicine essay, a movement disorders neurologist, whose examinations rely on gauging facial expressions, contemplates the complexities of day-to-day lost connectivity while wearing masks during the COVID-19 pandemic and savors now the renewed intimacies experienced face to face.

Editorial

Self-monitoring of Blood Pressure During Pregnancy

Malavika Prabhu, MD; Line Malha, MD; Laura E. Riley, MD

Abstract Full Text

has audio

JAMA. 2022;327(17):1651-1652. doi:10.1001/jama.2022.2802

Podcast: Effect of Self-monitoring of Blood Pressure on Detection and Assessment of Hypertension During Higher-Risk Pregnancy: The BUMP 1 and BUMP 2 Trials

The Potential Clinical Benefit of Lowering Lipoprotein(a)

Brian A. Ference, MD, MPhil, MSc

Abstract Full Text

has audio

JAMA. 2022;327(17):1653-1655. doi:10.1001/jama.2022.5333

Podcast: Highlights From the American College of Cardiology鈥檚 Scientific Sessions: New Heart Failure Management Guidelines and more

Review

Diagnosis and Management of Lumbar Spinal Stenosis: A Review

Jeffrey N. Katz, MD, MSc; Zoe E. Zimmerman, BS; Hanna Mass, BA; et al.

Abstract Full Text

has active quiz has audio

JAMA. 2022;327(17):1688-1699. doi:10.1001/jama.2022.5921

This review summarizes current evidence regarding diagnosis and treatment of acquired, degenerative, lumbar spinal stenosis.

Podcast: Lumbar Spinal Stenosis: A Review

JAMA Insights

Women's Health

Management of Chronic Hypertension During Pregnancy

Suchitra Chandrasekaran, MD, MSCE; Martina L. Badell, MD; Denise J. Jamieson, MD, MPH

Abstract Full Text

has active quiz has audio

JAMA. 2022;327(17):1700-1701. doi:10.1001/jama.2022.3919

This JAMA Insights discusses the importance of effectively diagnosing and managing chronic hypertension before, during, and after pregnancy for optimal maternal and child health.

Podcast: Effect of Self-monitoring of Blood Pressure on Detection and Assessment of Hypertension During Higher-Risk Pregnancy: The BUMP 1 and BUMP 2 Trials

JAMA Clinical Challenge

Urticaria 12 Days After COVID-19 mRNA Booster Vaccination

Anna R. Wolfson, MD; Esther E. Freeman, MD, PhD; Kimberly G. Blumenthal, MD, MSc

Abstract Full Text

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JAMA. 2022;327(17):1702-1703. doi:10.1001/jama.2022.5247

A woman developed pruritic wheals on her face and bilateral, transient eyelid swelling 12 days after receiving a COVID-19 mRNA booster vaccine (Moderna). During examination, wheal and flare lesions developed on her upper eyelids and resolved after 30 minutes; light pressure applied to her skin with a tongue depressor elicited wheal and flare lesions within 3 to 5 minutes. What is the diagnosis and what would you do next?

Medical News & Perspectives

Aging Out of Childhood Insomnia? Not Some Kids

Anita Slomski

Abstract Full Text

JAMA. 2022;327(17):1639-1640. doi:10.1001/jama.2022.5111

This Medical News article discusses insomnia in children.

News From the 糖心vlog

Studies Examine Risk of Hearing Loss After COVID-19 Vaccination

Anita Slomski

Abstract Full Text

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JAMA. 2022;327(17):1641. doi:10.1001/jama.2022.6719

Mindfulness-Based Therapy Reduces Chronic Pain and Opioid Misuse

Anita Slomski

Abstract Full Text

JAMA. 2022;327(17):1641. doi:10.1001/jama.2022.5330

Greater Excess Mortality in 2020 for People With Dementia

Anita Slomski

Abstract Full Text

JAMA. 2022;327(17):1641. doi:10.1001/jama.2022.6720

Antidepressant Combinations Compared With Monotherapy

Anita Slomski

Abstract Full Text

JAMA. 2022;327(17):1641. doi:10.1001/jama.2022.6721

News From the Food and Drug Administration

Targeted Radioligand Approved for Metastatic Prostate Cancer

Howard D. Larkin

Abstract Full Text

JAMA. 2022;327(17):1642. doi:10.1001/jama.2022.6661

First Amphetamine Transdermal Patch Approved for ADHD

Howard D. Larkin

Abstract Full Text

JAMA. 2022;327(17):1642. doi:10.1001/jama.2022.5727

First Donepezil Transdermal Patch Approved for Alzheimer Disease

Howard D. Larkin

Abstract Full Text

JAMA. 2022;327(17):1642. doi:10.1001/jama.2022.6662

Poetry and Medicine

Trauma Surgeon Ars Poetica

Maya J. Sorini, MS

Abstract Full Text

JAMA. 2022;327(17):1711. doi:10.1001/jama.2022.2843

JAMA Revisited

The Physiologic and Therapeutic Action of Light

Abstract Full Text

JAMA. 2022;327(17):1712. doi:10.1001/jama.2021.16954

JAMA Patient Page

Treatment of Menopause Symptoms With Hormone Therapy

Jill Jin, MD, MPH

Abstract Full Text

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JAMA. 2022;327(17):1716. doi:10.1001/jama.2022.5105

This JAMA Patient Page describes types of hormone therapy for treatment of menopause and the effectiveness and risk profiles of menopausal hormone therapies.

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