March 15, 2022 Issue of JAMA

March 15, 2022, Vol 327, No. 11, Pages 1011-1100

This Week in JAMA

Audio Highlights

Abstract Full Text

free access online only has audio

JAMA. 2022;327(11):e2116893. doi:10.1001/jama.2021.16893

Podcast: PTSD in Family Members After COVID-19 ICU Stay, Extended Anticoagulation for Venous Thromboembolism, Screening for Eating Disorders in Adolescents and Adults, and more

Original Investigation

Association of COVID-19 Vaccination With Symptomatic SARS-CoV-2 Infection by Time Since Vaccination and Delta Variant Predominance

Amadea Britton, MD; Katherine E. Fleming-Dutra, MD; Nong Shang, PhD; et al.

Abstract Full Text

free access has active quiz

JAMA. 2022;327(11):1032-1041. doi:10.1001/jama.2022.2068

This study estimates the associations between symptomatic SARS-CoV-2 infection and receipt of BNT162b2, mRNA-1273, and Ad26.COV2.S by day since vaccination before and during Delta variant predominance.

Caring for the Critically Ill Patient

Association of COVID-19 Acute Respiratory Distress Syndrome With Symptoms of Posttraumatic Stress Disorder in Family Members After ICU Discharge

Elie Azoulay, MD, PhD; Matthieu Resche-Rigon, MD, PhD; Bruno Megarbane, MD, PhD; et al.

Abstract Full Text

free access has active quiz

JAMA. 2022;327(11):1042-1050. doi:10.1001/jama.2022.2017

This prospective cohort study compares the risk of posttraumatic stress disorder among family members of patients with COVID-19-related acute respiratory distress syndrome (ARDS) vs ARDS from other causes.

Association of Type of Oral Anticoagulant Dispensed With Adverse Clinical Outcomes in Patients Extending Anticoagulation Therapy Beyond 90 Days After Hospitalization for Venous Thromboembolism

Ajinkya Pawar, PhD; Joshua J. Gagne, PharmD, ScD; Chandrasekar Gopalakrishnan, MD, MPH; et al.

Abstract Full Text

free access

JAMA. 2022;327(11):1051-1060. doi:10.1001/jama.2022.1920

This retrospective cohort study uses data from fee-for-service Medicare (2009-2017) and from 2 commercial health insurance (2004-2018) databases to compare extended prescription dispenses for apixaban, rivaroxaban, and warfarin after hospitalization for venous thromboembolism.

Research Letter

Prevalence and Durability of SARS-CoV-2 Antibodies Among Unvaccinated US Adults by History of COVID-19

Jennifer L. Alejo, MD; Jonathan Mitchell, MBBS; Amy Chang, MD; et al.

Abstract Full Text

free access has active quiz

JAMA. 2022;327(11):1085-1087. doi:10.1001/jama.2022.1393

This study uses serologic testing to characterize natural immunity and the long-term durability of SARS-CoV-2 antibodies among unvaccinated US adults by history of COVID-19 infection.

Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection

Lydia L. Shook, MD; Caroline G. Atyeo, BS; Lael M. Yonker, MD; et al.

Abstract Full Text

free access has active quiz

JAMA. 2022;327(11):1087-1089. doi:10.1001/jama.2022.1206

This study compares the persistence of anti-spike IgG titers in infants of vaccinated mothers vs mothers who had been naturally infected with COVID-19.

US Preventive Services Task Force

Recommendation Statement

Screening for Eating Disorders in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force

Abstract Full Text

free access has active quiz has audio

JAMA. 2022;327(11):1061-1067. doi:10.1001/jama.2022.1806

This 2022 Recommendation Statement from the US Preventive Services Task Force concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for eating disorders in adolescents and adults (I statement).

Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults

Editorial
Prevention and Early Identification of Eating Disorders
Evelyn Attia, MD; Angela S. Guarda, MD

JAMA
- Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults
New US Preventive Services Task Force Recommendations on Screening for Eating Disorders
Jason M. Nagata, MD, MSc; Neville H. Golden, MD

JAMA Intern Med
- Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults

Evidence Report

Screening for Eating Disorders in Adolescents and Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force

Cynthia Feltner, MD, MPH; Christine Peat, PhD; Shivani Reddy, MD, MS; et al.

Abstract Full Text

free access has active quiz has audio

JAMA. 2022;327(11):1068-1082. doi:10.1001/jama.2022.1807

This systematic review to support the 2022 US Preventive Services Task Force Recommendation Statement on screening for eating disorders summarizes published evidence on the benefits and harms of screening for eating disorders among adolescents and adults and of intervention for eating disorders among adolescent and adult populations with screen-detected or previously untreated eating disorders.

Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults

Editorial
Prevention and Early Identification of Eating Disorders
Evelyn Attia, MD; Angela S. Guarda, MD

JAMA
- Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults
New US Preventive Services Task Force Recommendations on Screening for Eating Disorders
Jason M. Nagata, MD, MSc; Neville H. Golden, MD

JAMA Intern Med
- Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults

Viewpoint

Switching to Over-the-Counter Availability of Rescue Inhalers for Asthma

William B. Feldman, MD, DPhil, MPH; Jerry Avorn, MD; Aaron S. Kesselheim, MD, JD, MPH

Abstract Full Text

JAMA. 2022;327(11):1021-1022. doi:10.1001/jama.2022.1160

This Viewpoint reviews the history of over-the-counter rescue inhalers and outlines why they again should be made available to patients with asthma without prescription from a physician.

Respiratory Protection for the Nation: A Report From the National Academies of Sciences, Engineering, and Medicine

Jonathan M. Samet, MD, MS; Stephanie M. Holm, MD, PhD, MPH; Sundaresan Jayaraman, PhD

Abstract Full Text

free access

JAMA. 2022;327(11):1023-1024. doi:10.1001/jama.2022.1318

This Viewpoint describes a report from the National Academies of Sciences, Engineering, and Medicine that proposes a framework for respiratory protection for individuals not provided with work-related equipment, including members of the public.

Navigating Clinical and Business Ethics While Sharing Patient Data

Kelly N. Michelson, MD, MPH; James G. Adams, MD; Joshua M. M. Faber, BA

Abstract Full Text

JAMA. 2022;327(11):1025-1026. doi:10.1001/jama.2022.1942

This Viewpoint discusses the gap between clinical medical ethics and some business practices related to patient data sharing and secondary use of data by corporations.

A Piece of My Mind

I Love You

Cara Anne Poland, MD, MEd

Abstract Full Text

JAMA. 2022;327(11):1027-1028. doi:10.1001/jama.2022.2668

In this narrative medicine essay, an addiction medicine physician describes her devastation in the wake of the deaths of her mother, brother, and grandfather and after the births of her children and longs for physicians to learn how to care for themselves and give space to colleagues when life happens.

Editorial

Prevention and Early Identification of Eating Disorders

Evelyn Attia, MD; Angela S. Guarda, MD

Abstract Full Text

free access has audio

JAMA. 2022;327(11):1029-1031. doi:10.1001/jama.2022.2458

Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults

Editorial
New US Preventive Services Task Force Recommendations on Screening for Eating Disorders
Jason M. Nagata, MD, MSc; Neville H. Golden, MD

JAMA Intern Med
- Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults

JAMA Guide to Statistics and Methods

Causal Directed Acyclic Graphs

Ari M. Lipsky, MD, PhD; Sander Greenland, MA, MS, DrPH

Abstract Full Text

has active quiz

JAMA. 2022;327(11):1083-1084. doi:10.1001/jama.2022.1816

This JAMA Guide to Statistics and Methods discusses the basics of causal directed acyclic graphs, which are useful tools for communicating researchers鈥� understanding of the potential interplay among variables and are commonly used for mediation analysis.

Medical News & Perspectives

Widespread Misinformation About Infertility Continues to Create COVID-19 Vaccine Hesitancy

Jennifer Abbasi

Abstract Full Text

free access has multimedia has audio

JAMA. 2022;327(11):1013-1015. doi:10.1001/jama.2022.2404

This Medical News article discusses ongoing misinformation that COVID-19 vaccines affect fertility and pregnancy outcomes.

Video: COVID-19 Vaccination During Pregnancy: Maternal Protection and Neonatal Immunity

Podcast: COVID-19 and Pregnancy: Disease Outcomes and Prevention With Vaccination

Highlights From the International Stroke Conference 2022鈥擳hrombectomy and Alteplase, Access to Stroke Centers, and Warfarin vs Direct Oral Anticoagulants

Melissa Suran, PhD, MSJ

Abstract Full Text

has audio

JAMA. 2022;327(11):1016-1018. doi:10.1001/jama.2022.2096

Timely topics discussed at the AHA/ASA鈥檚 International Stroke Conference included giving stroke patients intra-arterial alteplase following successful thrombectomy.

Podcast: Highlights From the International Stroke Conference

News From the Food and Drug Administration

Guidance for Development of Nonopioid Analgesics

Rita Rubin, MA

Abstract Full Text

JAMA. 2022;327(11):1020. doi:10.1001/jama.2022.3279

First Generic to Treat Dry Eye

Rita Rubin, MA

Abstract Full Text

JAMA. 2022;327(11):1020. doi:10.1001/jama.2022.2980

Another Step Toward Improving Nutrition by Reducing Sodium

Rita Rubin, MA

Abstract Full Text

JAMA. 2022;327(11):1020. doi:10.1001/jama.2022.3280

Global Health

Missing Child Mortality Targets Could Cost 11 Million Lives by 2030

Howard D. Larkin

Abstract Full Text

JAMA. 2022;327(11):1019. doi:10.1001/jama.2022.1871

Humanitarian Need Jumps in 2022

Howard D. Larkin

Abstract Full Text

JAMA. 2022;327(11):1019. doi:10.1001/jama.2022.3217

WHO Releases Report on Maintaining Health Services During COVID-19

Howard D. Larkin

Abstract Full Text

free access

JAMA. 2022;327(11):1019. doi:10.1001/jama.2022.3218

Poetry and Medicine

De Motu Cordis: On the Motion of the Heart

James M. Dowaliby II, MD

Abstract Full Text

JAMA. 2022;327(11):1094. doi:10.1001/jama.2021.22073

JAMA Revisited

鈥淭he Future Independence and Progress of American Medicine in the Age of Chemistry鈥�

Abstract Full Text

JAMA. 2022;327(11):1095. doi:10.1001/jama.2021.16894

JAMA Patient Page

Screening for Eating Disorders in Adolescents and Adults

Jill Jin, MD, MPH

Abstract Full Text

free access has audio

JAMA. 2022;327(11):1100. doi:10.1001/jama.2022.2428

This JAMA Patient Page summarizes the US Preventive Services Task Force鈥檚 recommendations on screening for eating disorders in adolescents and adults.

Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults

Editorial
Prevention and Early Identification of Eating Disorders
Evelyn Attia, MD; Angela S. Guarda, MD

JAMA
- Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults
New US Preventive Services Task Force Recommendations on Screening for Eating Disorders
Jason M. Nagata, MD, MSc; Neville H. Golden, MD

JAMA Intern Med
- Podcast: USPSTF Recommendation: Screening for Eating Disorders in Adolescents and Adults