March 8, 2022 Issue of JAMA

March 8, 2022, Vol 327, No. 10, Pages 897-1003

This Week in JAMA

Audio Highlights

Abstract Full Text

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JAMA. 2022;327(10):e2116883. doi:10.1001/jama.2021.16883

Podcast: Cardiac Arrest Outcomes in Pediatric ICUs, Tropical Cyclones and County-Level Mortality, Acute Kidney Injury After Cardiac Surgery, and more

Original Investigation

Caring for the Critically Ill Patient

Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial

The ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health; and Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups

Abstract Full Text

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JAMA. 2022;327(10):934-945. doi:10.1001/jama.2022.1738

This randomized trial evaluated whether physiologically structured debriefings and cardiopulmonary resuscitation training available in pediatric intensive care units improved survival with favorable neurologic results at discharge.

Association of Tropical Cyclones With County-Level Mortality in the US

Robbie M. Parks, PhD; Jaime Benavides, PhD; G. Brooke Anderson, PhD; et al.

Abstract Full Text

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JAMA. 2022;327(10):946-955. doi:10.1001/jama.2022.1682

This study uses data on tropical cyclones in the US and mortality data from the National Center for Health Statistics to evaluate the association of county-level tropical cyclone exposure and mortality rates from various causes in the US from 1998-2018.

Editorial
Advances in Estimating Mortality Associated With Tropical Cyclones in the US
James M. Shultz, MS, PhD; Lori Peek, PhD; Sandro Galea, MD, DrPH

JAMA

Predictive Accuracy of a Perioperative Laboratory Test鈥揃ased Prediction Model for Moderate to Severe Acute Kidney Injury After Cardiac Surgery

Sevag Demirjian, MD; C. Allen Bashour, MD; Andrew Shaw, MB; et al.

Abstract Full Text

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JAMA. 2022;327(10):956-964. doi:10.1001/jama.2022.1751

This study examines the predictive accuracy of models including early changes in serum creatinine and postsurgery laboratory parameters from the basic metabolic profile to predict postoperative moderate to severe acute kidney injury and acute kidney injury requiring dialysis in patients undergoing cardiac surgery.

Editorial
Predictive Models for Acute Kidney Injury Following Cardiac Surgery: The Importance of Accurate and Actionable Prediction
Marlies Ostermann, PhD, MD; Nuttha Lumlertgul, PhD; Francis Perry Wilson, MD, MSCE

JAMA
Acute Kidney Injury and the Field of Dreams鈥擨f We Predict It, Maybe They鈥檒l Come
John A. Kellum, MD; Faisal G. Bakaeen, MD; Danny Chu, MD

JAMA Surg

Research Letter

SARS-CoV-2 Infections in Close Contacts of Positive Cases in the Olympic and Paralympic Village at the 2021 Tokyo Olympic and Paralympic Games

Hidechika Akashi, MD, PhD, MPH, DTM&H; Satoshi Shimada, MD, PhD; Toyomitsu Tamura, MSc, RN; et al.

Abstract Full Text

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JAMA. 2022;327(10):978-980. doi:10.1001/jama.2022.0818

This study examines SARS-CoV-2 infections detected in close contacts of confirmed cases within the Olympic Village at the 2021 Tokyo Olympic and Paralympic Games.

Anti鈥揝ARS-CoV-2 Monoclonal Antibody Distribution to High-risk Medicare Beneficiaries, 2020-2021

Caroline L. Behr, AB; Karen E. Joynt Maddox, MD, MPH; Ellen Meara, PhD; et al.

Abstract Full Text

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JAMA. 2022;327(10):980-983. doi:10.1001/jama.2022.1243

This study assesses how a limited supply of monoclonal antibody therapy was allocated to patients at highest risk of severe disease among a population of fee-for-service Medicare beneficiaries with a new COVID-19 diagnosis or confirmed exposure between November 2020 and August 2021.

Viewpoint

Diagnostic Excellence

Achieving Diagnostic Excellence for Older Patients

Christine Cassel, MD; Terry Fulmer, PhD, RN

Abstract Full Text

JAMA. 2022;327(10):919-920. doi:10.1001/jama.2022.1813

This Viewpoint discusses the differences in disease expression, communication challenges, how complexity confounds the diagnostic process, the risks of ageism, and what defines diagnostic excellence for older adults.

Long-Acting Cabotegravir for HIV Prevention: Issues of Access, Cost, and Equity

Joshua M. Sharfstein, MD; Amy Killelea, JD; Derek Dangerfield, PhD

Abstract Full Text

JAMA. 2022;327(10):921-922. doi:10.1001/jama.2022.0420

This Viewpoint discusses the recent FDA approval of cabotegravir, the first injectable medication to help prevent HIV infection, and how its effectiveness may be complicated by the cost and complexity of the US health care system.

Updating the Bayh-Dole Act: March-in Rights and Transparency

Robert Cook-Deegan, MD; Aaron S. Kesselheim, MD, JD, MPH; Ameet Sarpatwari, PhD, JD

Abstract Full Text

JAMA. 2022;327(10):923-924. doi:10.1001/jama.2022.0895

This Viewpoint investigates how products developed from taxpayer investment should be managed and made accessible, and how updating the Bayh-Dole Act could help accomplish these goals.

A Piece of My Mind

The Labor of Story Telling

Megan Ann Brandeland, MD

Abstract Full Text

JAMA. 2022;327(10):925-926. doi:10.1001/jama.2022.2355

In this narrative medicine essay, a palliative care fellow shares the story of her father鈥檚 premature death and struggle with addiction that stemmed from an early-career catastrophic event to encourage physicians to tell their stories and break the stigma around mental health, trauma, and addiction.

Editorial

Predictive Models for Acute Kidney Injury Following Cardiac Surgery: The Importance of Accurate and Actionable Prediction

Marlies Ostermann, PhD, MD; Nuttha Lumlertgul, PhD; Francis Perry Wilson, MD, MSCE

Abstract Full Text

JAMA. 2022;327(10):927-929. doi:10.1001/jama.2022.1823

Advances in Estimating Mortality Associated With Tropical Cyclones in the US

James M. Shultz, MS, PhD; Lori Peek, PhD; Sandro Galea, MD, DrPH

Abstract Full Text

JAMA. 2022;327(10):929-931. doi:10.1001/jama.2022.0069

With Sincere Thanks and Appreciation to JAMA Authors and Reviewers

Phil B. Fontanarosa, MD, MBA; Robert M. Golub, MD; Annette Flanagin, RN, MA

Abstract Full Text

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JAMA. 2022;327(10):931-933. doi:10.1001/jama.2022.2791

Review

Acute Cholecystitis: A Review

Jared R. Gallaher, MD, MPH; Anthony Charles, MD, MPH

Abstract Full Text

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JAMA. 2022;327(10):965-975. doi:10.1001/jama.2022.2350

This Review summarizes the risk factors, pathogenesis, diagnosis, types of diagnostic studies, and treatment for patients with acute cholecystitis.

Podcast: Acute Cholecystitis

JAMA Clinical Guidelines Synopsis

Screening for Anxiety in Adolescent and Adult Women

Tiffany I. Leung, MD, MPH; Adam S. Cifu, MD; Wei Wei Lee, MD, MPH

Abstract Full Text

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JAMA. 2022;327(10):976-977. doi:10.1001/jama.2022.1647

This JAMA Clinical Guidelines Synopsis summarizes the 2020 Women鈥檚 Preventive Services Initiative recommendation on screening for anxiety in adolescent and adult women.

Medical News & Perspectives