This conversation is part of a series of interviews in which JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and expert guests explore issues surrounding the rapidly evolving intersection of artificial intelligence (AI) and medicine.

As a specialist in advanced brain mapping methods, Edward Chang, MD, set out to understand the mechanisms that turn our thoughts into words. Now, with the help of AI, his team at the University of California, San Francisco (UCSF) Weill Institute for Neurosciences has demonstrated that the brain signals associated with speech-related sensory and motor processes could grant a new voice to patients who have lost the ability to speak.