By generating bioengineered organoids of the liver, heart, and lungs and connecting them in a closed system with a nutrient-rich liquid to mimic the body鈥檚 circulatory system, researchers have created a 鈥渂ody-on-a-chip鈥� that may help reveal interorgan responses to drug or toxic chemical exposure. The potential to do so has implications for drug development, considering that many drugs have progressed through years of preclinical studies, clinical trials, and market availability before being recalled.