Explore the latest in research, methods, and statistics, including topics in clinical research infrastructure, design, conduct, and analysis.
This randomized clinical trial examines the use of a culturally tailored video for Black parents as a messaging tool to increase enrollment in pediatric clinical trials.
This cohort study assesses changes in parental decisions to donate fetal tissue after pregnancy termination since the introduction of the Dutch Fetal Biobank and factors associated with consent.
This cross-sectional study evaluates longitudinal cancer mortality trends among Asian American and Pacific Islander populations in the US by demographic characteristics.
This qualitative study engages with clinicians, patients, and care partners to better understand the experience of collecting, documenting, and sharing social determinant of health data.
This cross-sectional study evaluates representation of Native Hawaiian and Pacific Islander Individuals in clinical trials that led to the first US Food and Drug Administration approval for 10 widely used drugs.
This systematic review assesses participant flow in neonatal clinical trials and reasons for noninclusion of eligible participants.
This JAMA Special Communication presents the 2024 revision of the World Medical Association鈥檚 Declaration of Helsinki, a set of principles to guide the ethical treatment of participants in medical research.
This Special Communication examines ethical oversight of clinical research in the US and offers practical recommendations that are consistent with current regulations and that could help to make research oversight better fit for purpose for different types of studies.
This Viewpoint discusses significant revisions in the Declaration of Helsinki in response to changing ethical norms and technologies.
This Viewpoint explores the 2024 update to the Declaration of Helsinki from the perspective of the Americas and how countries in this region can implement the Declaration鈥檚 guidance to ethically govern scientific health research.
This Viewpoint discusses key revisions of the Declaration of Helsinki 2024 in the context of internationally accepted ethical guidance for human research.
This Viewpoint contextualizes the history of the Declaration of Helsinki, analyzes the implications of its latest revision, and emphasizes the need for patient-centricity in research ethics.
This Viewpoint discusses the 2024 revisions made to the Declaration of Helsinki as it continues to work toward ensuring research is subject to ethical standards that promote respect for all human participants and protect their rights and interests.
This Viewpoint summarizes recent updates to the Declaration of Helsinki, discusses its relevance in the context of artificial intelligence (AI) in health research, and highlights issues that could affect its future implementation as the use of AI in research increases.
This cross-sectional study uses network analysis methods to identify emergency general surgery (EGS) care regions in New York and California and compares this method of identification with Dartmouth health referral regions.
This survey study examines the opinions of US Food and Drug Administration (FDA) panel members regarding the premarket approval process for devices.
This cohort study estimates disparities in doses of opioid agonist medication to treat opioid use disorder among Black, Hispanic, and White patients in 3 clinical trials.
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