Explore the latest in antibiotic use, overuse, resistance, and stewardship, including evolving antimicrobial susceptibility patterns and more.
This Medical News article discusses the first high-level meeting on antimicrobial resistance at the United Nations since 2016 and a new report on the global burden of bacterial antimicrobial resistance.
This cohort study evaluates the performance of a risk stratification model for resistant gram-negative bacilli infection among patients with sepsis.
This systematic review and meta-analysis investigates the prevalence of colonization with antibiotic-resistant bacterial pathogens in the first 3 months of life in low- and middle-income countries (LMICs).
This consensus statement creates a clinical guideline for the diagnosis and management of urinary tract infections that addresses the gap between the evidence and recommendation strength.
This cohort study examines the frequency with which children diagnosed with pneumonia in outpatient settings do not receive antibiotics and compares the risk of treatment failure and severe outcomes between children who receive antibiotics and those who do not.
This Viewpoint discusses the shortage of penicillin G benzathine during a surge in congenital syphilis cases in the US.
This cross-sectional study examined clinic characteristics associated with antibiotic prescribing for acute respiratory infections in primary care in Japan.
This JAMA Insights examines antibiotic selection for the treatment of acute bacterial rhinosinusitis in US pediatric patients, specifically amoxicillin vs amoxicillin-clavulanate.
A child aged 4 years presented with a 3-day history of worsening redness, pain, and swelling over the left lower eyelid and nose. Visual acuity was normal, and systemic examination revealed cervical lymphadenopathy and hepatosplenomegaly. The patient showed no improvement after 3 days of intravenous ceftriaxone, and a computed tomography scan showed a collection in the lacrimal sac. What would you do next?
This cross-sectional study examines the factors associated with optimal antibiotic choice, duration, and both choice and duration among outpatients younger than 20 years in Tennessee.
This cohort study examines whether treatment with nirmatrelvir and remdesivir is associated with emergent antiviral resistance in SARS-CoV-2 strains.
This meta-analysis assesses the antimicrobial susceptibility of Staphylococcus aureus in individuals with atopic dermatitis and analyzes differences according to the income level of country of origin and the data collection period.
This prognostic study explores the optimal frequency and timing of point prevalence surveys to collect data on antibiotic use among the pediatric population in inpatient and outpatient settings.
This Review summarizes current evidence on pathogenesis, epidemiology, diagnosis, and treatment of community-acquired pneumonia and focuses on adults without immune-compromising conditions.
This systematic review and meta-analysis evaluates the frequency of reactions to direct penicillin challenges in individuals with penicillin allergy labels across diverse patient populations.
This narrative review outlines diagnostic and treatment approaches to necrotizing soft tissue infections and suggests future directions while mentioning promising developments in their management.
This JAMA Clinical Guidelines Synopsis summarizes the 2022 recommendations on evaluation of suspected antibiotic allergies from the American Academy of Allergy, Asthma & Immunology and American College of Allergy, Asthma & Immunology.
This cross-sectional study assesses whether short-term exposures to ambient air pollution are associated with an increase in antimicrobial consumption among the general population seeking primary care consultations for acute respiratory symptoms.
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