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What is Alzheimer's disease and how is it detected?

What is Alzheimer's disease and how is it detected?
SEVEN NEWS. MORE THAN 53,000 NEW MEXICANS ARE EXPECTED TO HAVE ALZHEIMER’S DISEASE BY 2025. THE ALZHEIMER’S ASSOCIATION SAYS THAT’S AN INCREASE OF 2000 PEOPLE PER YEAR. WE ASKED KOAT, UNM HEALTH EXPERT DOCTOR ASH ABOUT THIS. ALZHEIMER’S DISEASE IS A BRAIN DISORDER THAT SLOWLY DESTROYS MEMORY AND THINKING SKILLS, AND EVENTUALLY THE ABILITY TO CARRY OUT THE SIMPLEST TASKS. IT’S THE MOST COMMON CAUSE OF DEMENTIA AMONG OLDER ADULTS. LATE ONSET TYPE SYMPTOMS FIRST APPEAR IN THEIR MID 60S, BUT THERE’S EARLY ONSET ALZHEIMER’S THAT OCCURS BETWEEN A PERSON’S AGE OF 30 TO 60. AND THIS IS ALSO VERY RARE. THE MAIN FEATURES ARE PLAQUES AND TANGLES IN THE BRAIN. ANOTHER FEATURE IS A LOSS OF CONNECTION BETWEEN NERVE CELLS OR NEURONS IN THE BRAIN. SO THE BIG QUESTION IS HOW DO WE DIAGNOSE THE DISEASE? DOCTORS USE MEDICAL HISTORY, MENTAL STATUS TESTS, PHYSICAL AND NEUROLOGICAL EXAMINATIONS, DIAGNOSTIC TESTS, AND FINALLY SOME BRAIN IMAGING. BUT WE KNOW THERE’S THESE TOXIC AGGREGATES. THEY’RE CALLED OLIGOMERS. THEY CAN START TO FORM MORE THAN A DECADE BEFORE SYMPTOMS APPEAR AND BEFORE OTHER KNOWN DISEASE MARKERS FORM. THE ABILITY TO DETECT THESE OLIGOMERS WOULD ALLOW DOCTORS TO INTERVENE BEFORE IRREPARABLE BRAIN DAMAGE OCCURS. DOCTOR ASH ALSO SAYS RESEARCHERS ARE WORKING TO DEVELOP A BLOOD TEST THAT COULD DETECT ALZH
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What is Alzheimer's disease and how is it detected?
Investigators released the cause of death for Gene Hackman and his wife Betsy Arakawa on Friday.The New Mexico Office of the Medical Investigator says Hackman died from a cardiovascular disease with Alzheimer's being a contributing factor. What is Alzheimer's disease?Sister station KOAT and University of New Mexico health expert Dr. Abinash Achrekar explained what the disease is."Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks," Achrekar said. "It is the most common cause of dementia among older adults."Diagnoses of the memory-loss disease normally happens after the age of 60."Late-onset type symptoms first appear in their mid-60s," Achrekar said. "Early onset Alzheimer's occurs between a person's 30s and mid-60s and is very rare. "The main features of Alzheimer's disease include plaques and tangles in the brain. Another feature is the loss of connections between nerve cells (neurons) in the brain."How do medical professionals diagnose the disease?"Doctors use medical history, mental status tests, physical and neurological exams, diagnostic tests and brain imaging," Achrekar said. "But we know toxic aggregates, called oligomers, can start to form more than a decade before symptoms appear and before other known disease markers form."Achrekar explains how the knowledge and detection of oligomers can assist in the long-term health care treatment of Alzheimer's disease."The ability to detect these oligomers would allow doctors to intervene before irreparable brain damage occurs possible," Achrekar said.Achrekar also said researchers are working to create a blood test that can detect the disease. This test could hypothetically detect Alzheimer's disease long before any late-onset symptoms occur.

Investigators released the cause of death for Gene Hackman and his wife Betsy Arakawa on Friday.

The New Mexico Office of the Medical Investigator says Hackman died from a cardiovascular disease with Alzheimer's being a contributing factor.

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What is Alzheimer's disease?

Sister station KOAT and University of New Mexico health expert Dr. Abinash Achrekar explained what the disease is.

"Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks," Achrekar said. "It is the most common cause of dementia among older adults."

Diagnoses of the memory-loss disease normally happens after the age of 60.

"Late-onset type symptoms first appear in their mid-60s," Achrekar said. "Early onset Alzheimer's occurs between a person's 30s and mid-60s and is very rare.

"The main features of Alzheimer's disease include plaques and tangles in the brain. Another feature is the loss of connections between nerve cells (neurons) in the brain."

How do medical professionals diagnose the disease?

"Doctors use medical history, mental status tests, physical and neurological exams, diagnostic tests and brain imaging," Achrekar said. "But we know toxic aggregates, called oligomers, can start to form more than a decade before symptoms appear and before other known disease markers form."

Achrekar explains how the knowledge and detection of oligomers can assist in the long-term health care treatment of Alzheimer's disease.

"The ability to detect these oligomers would allow doctors to intervene before irreparable brain damage occurs possible," Achrekar said.

Achrekar also said researchers are working to create a blood test that can detect the disease. This test could hypothetically detect Alzheimer's disease long before any late-onset symptoms occur.